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The map label for this gene is mdtA [H]

Identifier: 170023574

GI number: 170023574

Start: 1466769

End: 1468103

Strand: Reverse

Name: mdtA [H]

Synonym: YPK_1332

Alternate gene names: 170023574

Gene position: 1468103-1466769 (Counterclockwise)

Preceding gene: 170023575

Following gene: 170023573

Centisome position: 31.31

GC content: 54.16

Gene sequence:

>1335_bases
ATGAAATCTCAATCCAAACGCACTTCCCGATTATTCGTATTCGTGGGGGTAGTGGTGGCGATCATTATTGCGGTGCTTAG
TTGGCGCTACTTTGGTACCGGCTCCGATAACAATACGTCAGGTGCTCAGCAGAGTGCCCGTGGTCAGGACACTAGCCATG
GTGGCCGCCGTAATACACCGCTGGCACCGGTGCAAGCCGCAACCGCAACCGAGCAGGAAGTGCCACGTTATCTCACTGGC
TTAGGGACGGTCATTGCCGCCAATACTGTCACGGTAACCAGCCGAGTTGATGGTGAATTGATGGCCCTTCATTTCACTGA
AGGGCAGCAGGTTAAGGCTGGCGACTTACTGGCAGAGATCGACCCCCGCCCTTACGAAGTCCAACTGACGCAGGCTCAGG
GGCAGTTGGCCAAAGATCAGGCCACGCTGGATAACGCCCGTCGTGATCTGGCCCGTTATCAGAAATTGTCCAAAACTGGC
CTGATTTCGCAACAGGAACTGGATACGCAATCTTCGCTGGTACGCCAGAGCGAGGGCAGTGTGAAAGCCGATCAGGGCGC
TATCGACAGCGCCAAATTGCAACTGACGTATAGCCGTATTACCGCGCCTATCTCCGGTAGAGTGGGCCTGAAACAAGTGG
ATGTCGGCAATTACATTACCAGCGGCACGGCCACACCGATTGTGGTGATCACCCAGACACATCCCGTTGATGTGGTCTTT
ACCCTGCCAGAAAGCGATATTCCCGCCATTATGCAAGCACAGAAAAATGCGGAGAAGACTCACGCCATCGTGCCCGTTGA
AGCGTGGGATCGGACGAATAAACAGATGCTGGCACAGGGCTACCTGCTCAGTATTGATAACCAGATTGATACCACGACGG
GCACCATTAAACTGAAAGCCCGCTTTAATAATGAAGATGATGTGCTGTTCCCTAATCAGTTTGTTAACGCCCGTATCAAG
GTCGATTTGCTGCAAAATGCTGTCGTGGTGCCCACCGCAGCGGTACAAATGGGCAGCGAAGGTAACTTTGTCTGGACGTT
AGATGATGCAAATAAAGTCAGCAAACATCTGGTCACCACCGGGATTCAGAATAGCCAACAAGTGGTTATCGACGCAGGCC
TGAACGCTGGGCAACGCGTGGTCACGGATGGTATTGATCGCCTGACCGAGGGAGTACAGGTTGAAGTGGTGACACCACGC
AGCGCCAATACTGACACTAATCCAGCCAGTGCAGAGAAAGCGGCTGCAGAAGCAGAAGGCAGCACCCCGCATCAAGGCCG
AGGGCGTCCGGCCAATGCGCCTGCACGTAGCACCACGGCTGCGGAGAAATCCTGA

Upstream 100 bases:

>100_bases
TATCCGGTAATTGCCCGTTAAACTAGTAGCATATCCGAAAACTCAGAGACTGCGCCCATGTGGTGCAGGTAGCCACGATA
AAAAAGGACGCTTCGCCATC

Downstream 100 bases:

>100_bases
TGCAAGTGATGCCTCCAACACCCGGTGGCGGGCCGTCACGGCTGTTTATTCTGCGCCCGGTCGCCACCACATTATTTATG
ATCGCGATTTTACTGGCCGG

Product: multidrug efflux system subunit MdtA

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 444; Mature: 444

Protein sequence:

>444_residues
MKSQSKRTSRLFVFVGVVVAIIIAVLSWRYFGTGSDNNTSGAQQSARGQDTSHGGRRNTPLAPVQAATATEQEVPRYLTG
LGTVIAANTVTVTSRVDGELMALHFTEGQQVKAGDLLAEIDPRPYEVQLTQAQGQLAKDQATLDNARRDLARYQKLSKTG
LISQQELDTQSSLVRQSEGSVKADQGAIDSAKLQLTYSRITAPISGRVGLKQVDVGNYITSGTATPIVVITQTHPVDVVF
TLPESDIPAIMQAQKNAEKTHAIVPVEAWDRTNKQMLAQGYLLSIDNQIDTTTGTIKLKARFNNEDDVLFPNQFVNARIK
VDLLQNAVVVPTAAVQMGSEGNFVWTLDDANKVSKHLVTTGIQNSQQVVIDAGLNAGQRVVTDGIDRLTEGVQVEVVTPR
SANTDTNPASAEKAAAEAEGSTPHQGRGRPANAPARSTTAAEKS

Sequences:

>Translated_444_residues
MKSQSKRTSRLFVFVGVVVAIIIAVLSWRYFGTGSDNNTSGAQQSARGQDTSHGGRRNTPLAPVQAATATEQEVPRYLTG
LGTVIAANTVTVTSRVDGELMALHFTEGQQVKAGDLLAEIDPRPYEVQLTQAQGQLAKDQATLDNARRDLARYQKLSKTG
LISQQELDTQSSLVRQSEGSVKADQGAIDSAKLQLTYSRITAPISGRVGLKQVDVGNYITSGTATPIVVITQTHPVDVVF
TLPESDIPAIMQAQKNAEKTHAIVPVEAWDRTNKQMLAQGYLLSIDNQIDTTTGTIKLKARFNNEDDVLFPNQFVNARIK
VDLLQNAVVVPTAAVQMGSEGNFVWTLDDANKVSKHLVTTGIQNSQQVVIDAGLNAGQRVVTDGIDRLTEGVQVEVVTPR
SANTDTNPASAEKAAAEAEGSTPHQGRGRPANAPARSTTAAEKS
>Mature_444_residues
MKSQSKRTSRLFVFVGVVVAIIIAVLSWRYFGTGSDNNTSGAQQSARGQDTSHGGRRNTPLAPVQAATATEQEVPRYLTG
LGTVIAANTVTVTSRVDGELMALHFTEGQQVKAGDLLAEIDPRPYEVQLTQAQGQLAKDQATLDNARRDLARYQKLSKTG
LISQQELDTQSSLVRQSEGSVKADQGAIDSAKLQLTYSRITAPISGRVGLKQVDVGNYITSGTATPIVVITQTHPVDVVF
TLPESDIPAIMQAQKNAEKTHAIVPVEAWDRTNKQMLAQGYLLSIDNQIDTTTGTIKLKARFNNEDDVLFPNQFVNARIK
VDLLQNAVVVPTAAVQMGSEGNFVWTLDDANKVSKHLVTTGIQNSQQVVIDAGLNAGQRVVTDGIDRLTEGVQVEVVTPR
SANTDTNPASAEKAAAEAEGSTPHQGRGRPANAPARSTTAAEKS

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=390, Percent_Identity=66.6666666666667, Blast_Score=514, Evalue=1e-147,
Organism=Escherichia coli, GI1789665, Length=362, Percent_Identity=30.939226519337, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1789929, Length=330, Percent_Identity=28.4848484848485, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1786668, Length=403, Percent_Identity=30.7692307692308, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI87081951, Length=168, Percent_Identity=33.9285714285714, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI87081796, Length=345, Percent_Identity=25.5072463768116, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1790519, Length=235, Percent_Identity=25.1063829787234, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 47563; Mature: 47563

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSQSKRTSRLFVFVGVVVAIIIAVLSWRYFGTGSDNNTSGAQQSARGQDTSHGGRRNTP
CCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCHHHCCCCCCCCCCCCCCC
LAPVQAATATEQEVPRYLTGLGTVIAANTVTVTSRVDGELMALHFTEGQQVKAGDLLAEI
CCCCHHHCCCHHHHHHHHHHHHHEEEECEEEEEEECCCEEEEEEECCCCEEECCCCCEEC
DPRPYEVQLTQAQGQLAKDQATLDNARRDLARYQKLSKTGLISQQELDTQSSLVRQSEGS
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHCCCC
VKADQGAIDSAKLQLTYSRITAPISGRVGLKQVDVGNYITSGTATPIVVITQTHPVDVVF
CCCCCCCCCCEEEEEEEHHCCCCCCCCCCCEEEECCCEECCCCCCEEEEEEECCCEEEEE
TLPESDIPAIMQAQKNAEKTHAIVPVEAWDRTNKQMLAQGYLLSIDNQIDTTTGTIKLKA
ECCCCCCCHHHHHHHCCCCCEEEEEEHHCCCCCHHHHHCCEEEEECCCCCCCCEEEEEEE
RFNNEDDVLFPNQFVNARIKVDLLQNAVVVPTAAVQMGSEGNFVWTLDDANKVSKHLVTT
EECCCCCEECCHHHCCCEEEEEECCCEEEEEEHHEEECCCCCEEEEECCHHHHHHHHHHH
GIQNSQQVVIDAGLNAGQRVVTDGIDRLTEGVQVEVVTPRSANTDTNPASAEKAAAEAEG
CCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHCCC
STPHQGRGRPANAPARSTTAAEKS
CCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKSQSKRTSRLFVFVGVVVAIIIAVLSWRYFGTGSDNNTSGAQQSARGQDTSHGGRRNTP
CCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCHHHCCCCCCCCCCCCCCC
LAPVQAATATEQEVPRYLTGLGTVIAANTVTVTSRVDGELMALHFTEGQQVKAGDLLAEI
CCCCHHHCCCHHHHHHHHHHHHHEEEECEEEEEEECCCEEEEEEECCCCEEECCCCCEEC
DPRPYEVQLTQAQGQLAKDQATLDNARRDLARYQKLSKTGLISQQELDTQSSLVRQSEGS
CCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHCCCC
VKADQGAIDSAKLQLTYSRITAPISGRVGLKQVDVGNYITSGTATPIVVITQTHPVDVVF
CCCCCCCCCCEEEEEEEHHCCCCCCCCCCCEEEECCCEECCCCCCEEEEEEECCCEEEEE
TLPESDIPAIMQAQKNAEKTHAIVPVEAWDRTNKQMLAQGYLLSIDNQIDTTTGTIKLKA
ECCCCCCCHHHHHHHCCCCCEEEEEEHHCCCCCHHHHHCCEEEEECCCCCCCCEEEEEEE
RFNNEDDVLFPNQFVNARIKVDLLQNAVVVPTAAVQMGSEGNFVWTLDDANKVSKHLVTT
EECCCCCEECCHHHCCCEEEEEECCCEEEEEEHHEEECCCCCEEEEECCHHHHHHHHHHH
GIQNSQQVVIDAGLNAGQRVVTDGIDRLTEGVQVEVVTPRSANTDTNPASAEKAAAEAEG
CCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHCCC
STPHQGRGRPANAPARSTTAAEKS
CCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA