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The map label for this gene is baeS [H]

Identifier: 170023570

GI number: 170023570

Start: 1457693

End: 1459078

Strand: Reverse

Name: baeS [H]

Synonym: YPK_1328

Alternate gene names: 170023570

Gene position: 1459078-1457693 (Counterclockwise)

Preceding gene: 170023571

Following gene: 170023569

Centisome position: 31.11

GC content: 51.59

Gene sequence:

>1386_bases
ATGATAAGGATCGGCATTACCGGAAAACTGTTTATGGCTATTTTCGCCACTTGCATGTTGGTATTGATAACCATGCACTG
GGGCGTCAGGACCAGTTTTGAACGCGGTTTCATTGACTACATCAAGCAAAGTAATGAACAGCGGATCGCCATGCTAAGTC
ATGCGCTTGAAGGCGAATATCAGCACTACGGTAACTGGGATTTTCTGCGTAATAATGACCAAGTGATTTACCAGATCATG
CGATCCTTTGAGCAAAACCAAAACAGTGAGAGCAGACCCAGTATGCCGCCCCGTGGCTGGCGCGCCCAATTTTGGGTGGT
TGATCAAGACAATAATCTGCTGGTCGGGCACTCCGGGCATCTCCCCACAGAAGCTAGCCGCAGTGCCATAAAAGTCAATG
ATCAGGTTGTCGGCTGGGTGATTTCGACCCCATCGGAAAAACTGACCCGTAATGCAGATATCACCTTTGATCAACAACAG
CGCCGCACCAGTTGGTTTATTGTTGGCCTCTCGACGCTGCTGGCGGCCGCCGTCACATGGGTACTCTCACGCGGCATGTT
AGCCCCAGTAAAACGGCTGGTTGAAGGCACGCATCGGCTGGCCGCGGGGGATTTTAGCACCCGTGTTGCCGTCAGTAGCC
GCGATGAACTGGGCCACCTGGCACAAGATTTTAACCAGCTAGCCAGTTCACTGGAAAAAAATGAACAAATGCGCCGTGAT
TTTATGGCCGATGTCTCCCATGAACTCCGCACGCCACTGGCAGTATTACGCGGAGAACTGGAAGCCTTACAAGACGGCCT
GCGCCAACCCACCCCCGAGTCATTAAGTTCGCTCCAAGCCGAGGTGGCGATTTTGACAAAACTGGTCAATGACCTGCACC
AGTTATCACAGTCTGATCGCGGGGCGCTGGCTTACCGTAAAACCCAACTGGATGTGGTCCGGCTACTGCAAGTGGCGATT
GCCAGCTTTCATGGCCGCTTCCAGAACAAAAAGATGACCATCACCGCCCACCTGCCTGAACACGCGGTTATTTTTGGCGA
CCCTGACCGGCTCAATCAGTTATTTCACAATTTACTGGAAAACAGCCTGCGTTATACCAACGAGGGGGGGGCATTAGAAA
TTATCGCGTTGATCCAAGAAGAGACACTCACGCTGCACTGGCAAGACAGTAAACCGGGGGTCAGCGATGAACAGCTCGAG
CGTCTTTTTGAACGTTTTTATCGTACGGAAAGTTCACGTAATCGCGCCAGTGGCGGCTCTGGGTTGGGGTTGGCGATTTG
CCATAATATTGTCGATGCGCATAGTGGAAAAATCAGCGCTAAACATTCACCTTTGGGTGGCCTGCGGATTACGGTAGTAT
TCCCCCTATTTCATTCCATAGGGTAA

Upstream 100 bases:

>100_bases
CGCCCTACCCGCCCTGATATTTAACCGCGTTCCCCCGGATACAGGAGCCAATCGTCATTTGGCCCGCTAGATTGGCCGAC
TGATAAAGACAGGTGAAATT

Downstream 100 bases:

>100_bases
TCCATTGTAATGCACGAGTCGCTTCTGTCTGCCAGCCAGTCTGGCTCTGTATTGATCGTTGAAGATGAACCCAAACTTGG
CCAGCTACTCGTCGATTACC

Product: signal transduction histidine-protein kinase BaeS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MIRIGITGKLFMAIFATCMLVLITMHWGVRTSFERGFIDYIKQSNEQRIAMLSHALEGEYQHYGNWDFLRNNDQVIYQIM
RSFEQNQNSESRPSMPPRGWRAQFWVVDQDNNLLVGHSGHLPTEASRSAIKVNDQVVGWVISTPSEKLTRNADITFDQQQ
RRTSWFIVGLSTLLAAAVTWVLSRGMLAPVKRLVEGTHRLAAGDFSTRVAVSSRDELGHLAQDFNQLASSLEKNEQMRRD
FMADVSHELRTPLAVLRGELEALQDGLRQPTPESLSSLQAEVAILTKLVNDLHQLSQSDRGALAYRKTQLDVVRLLQVAI
ASFHGRFQNKKMTITAHLPEHAVIFGDPDRLNQLFHNLLENSLRYTNEGGALEIIALIQEETLTLHWQDSKPGVSDEQLE
RLFERFYRTESSRNRASGGSGLGLAICHNIVDAHSGKISAKHSPLGGLRITVVFPLFHSIG

Sequences:

>Translated_461_residues
MIRIGITGKLFMAIFATCMLVLITMHWGVRTSFERGFIDYIKQSNEQRIAMLSHALEGEYQHYGNWDFLRNNDQVIYQIM
RSFEQNQNSESRPSMPPRGWRAQFWVVDQDNNLLVGHSGHLPTEASRSAIKVNDQVVGWVISTPSEKLTRNADITFDQQQ
RRTSWFIVGLSTLLAAAVTWVLSRGMLAPVKRLVEGTHRLAAGDFSTRVAVSSRDELGHLAQDFNQLASSLEKNEQMRRD
FMADVSHELRTPLAVLRGELEALQDGLRQPTPESLSSLQAEVAILTKLVNDLHQLSQSDRGALAYRKTQLDVVRLLQVAI
ASFHGRFQNKKMTITAHLPEHAVIFGDPDRLNQLFHNLLENSLRYTNEGGALEIIALIQEETLTLHWQDSKPGVSDEQLE
RLFERFYRTESSRNRASGGSGLGLAICHNIVDAHSGKISAKHSPLGGLRITVVFPLFHSIG
>Mature_461_residues
MIRIGITGKLFMAIFATCMLVLITMHWGVRTSFERGFIDYIKQSNEQRIAMLSHALEGEYQHYGNWDFLRNNDQVIYQIM
RSFEQNQNSESRPSMPPRGWRAQFWVVDQDNNLLVGHSGHLPTEASRSAIKVNDQVVGWVISTPSEKLTRNADITFDQQQ
RRTSWFIVGLSTLLAAAVTWVLSRGMLAPVKRLVEGTHRLAAGDFSTRVAVSSRDELGHLAQDFNQLASSLEKNEQMRRD
FMADVSHELRTPLAVLRGELEALQDGLRQPTPESLSSLQAEVAILTKLVNDLHQLSQSDRGALAYRKTQLDVVRLLQVAI
ASFHGRFQNKKMTITAHLPEHAVIFGDPDRLNQLFHNLLENSLRYTNEGGALEIIALIQEETLTLHWQDSKPGVSDEQLE
RLFERFYRTESSRNRASGGSGLGLAICHNIVDAHSGKISAKHSPLGGLRITVVFPLFHSIG

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=456, Percent_Identity=65.5701754385965, Blast_Score=600, Evalue=1e-173,
Organism=Escherichia coli, GI1790346, Length=272, Percent_Identity=29.7794117647059, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1787894, Length=269, Percent_Identity=29.368029739777, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1786600, Length=283, Percent_Identity=30.0353356890459, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1786783, Length=289, Percent_Identity=26.9896193771626, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1786912, Length=274, Percent_Identity=30.2919708029197, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI145693157, Length=252, Percent_Identity=27.7777777777778, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1787374, Length=303, Percent_Identity=28.3828382838284, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI1788713, Length=243, Percent_Identity=28.8065843621399, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790861, Length=307, Percent_Identity=27.0358306188925, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1789149, Length=381, Percent_Identity=24.9343832020997, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI87081816, Length=340, Percent_Identity=24.7058823529412, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1788279, Length=282, Percent_Identity=24.822695035461, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1789403, Length=290, Percent_Identity=27.5862068965517, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1789808, Length=286, Percent_Identity=27.2727272727273, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1790551, Length=278, Percent_Identity=28.4172661870504, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1790436, Length=218, Percent_Identity=27.9816513761468, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082128, Length=276, Percent_Identity=26.8115942028986, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI48994928, Length=224, Percent_Identity=24.5535714285714, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788549, Length=222, Percent_Identity=25.2252252252252, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1790300, Length=232, Percent_Identity=28.8793103448276, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51941; Mature: 51941

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRIGITGKLFMAIFATCMLVLITMHWGVRTSFERGFIDYIKQSNEQRIAMLSHALEGEY
CEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCH
QHYGNWDFLRNNDQVIYQIMRSFEQNQNSESRPSMPPRGWRAQFWVVDQDNNLLVGHSGH
HHCCCCCEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCEEEECCCC
LPTEASRSAIKVNDQVVGWVISTPSEKLTRNADITFDQQQRRTSWFIVGLSTLLAAAVTW
CCCCCCCCEEEECCEEEEEEEECCHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHH
VLSRGMLAPVKRLVEGTHRLAAGDFSTRVAVSSRDELGHLAQDFNQLASSLEKNEQMRRD
HHHCCHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FMADVSHELRTPLAVLRGELEALQDGLRQPTPESLSSLQAEVAILTKLVNDLHQLSQSDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GALAYRKTQLDVVRLLQVAIASFHGRFQNKKMTITAHLPEHAVIFGDPDRLNQLFHNLLE
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEECCHHHHHHHHHHHHH
NSLRYTNEGGALEIIALIQEETLTLHWQDSKPGVSDEQLERLFERFYRTESSRNRASGGS
HHHCCCCCCCCEEEEEEEECCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
GLGLAICHNIVDAHSGKISAKHSPLGGLRITVVFPLFHSIG
CHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEHHHHHHHCC
>Mature Secondary Structure
MIRIGITGKLFMAIFATCMLVLITMHWGVRTSFERGFIDYIKQSNEQRIAMLSHALEGEY
CEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCH
QHYGNWDFLRNNDQVIYQIMRSFEQNQNSESRPSMPPRGWRAQFWVVDQDNNLLVGHSGH
HHCCCCCEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCEEEECCCC
LPTEASRSAIKVNDQVVGWVISTPSEKLTRNADITFDQQQRRTSWFIVGLSTLLAAAVTW
CCCCCCCCEEEECCEEEEEEEECCHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHH
VLSRGMLAPVKRLVEGTHRLAAGDFSTRVAVSSRDELGHLAQDFNQLASSLEKNEQMRRD
HHHCCHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FMADVSHELRTPLAVLRGELEALQDGLRQPTPESLSSLQAEVAILTKLVNDLHQLSQSDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GALAYRKTQLDVVRLLQVAIASFHGRFQNKKMTITAHLPEHAVIFGDPDRLNQLFHNLLE
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEECCHHHHHHHHHHHHH
NSLRYTNEGGALEIIALIQEETLTLHWQDSKPGVSDEQLERLFERFYRTESSRNRASGGS
HHHCCCCCCCCEEEEEEEECCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
GLGLAICHNIVDAHSGKISAKHSPLGGLRITVVFPLFHSIG
CHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]