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The map label for this gene is mlaC [H]

Identifier: 170022766

GI number: 170022766

Start: 565518

End: 566141

Strand: Direct

Name: mlaC [H]

Synonym: YPK_0515

Alternate gene names: 170022766

Gene position: 565518-566141 (Clockwise)

Preceding gene: 170022765

Following gene: 170022767

Centisome position: 12.06

GC content: 48.4

Gene sequence:

>624_bases
ATGTTTAAACGTCTATTCATGGTCGCATTGTTGGCCATAGCACCACTGGTTCATGCTGTCGATCAAAGCAACCCTTATCG
TCTGATGGATGAGGCAGCGAAGAAAACCTTTACGCGTCTGAAAAATGAGCAGCCTAAGATTAAGCAAAATCCAGATTATC
TCCGCACCATTGTACGCGAAGAGCTGTTGCCGTTTGTTCAGATCAAATACGCCGGCGCGTTAGTACTGGGTAGCTATTAT
AAAGATGCTACACCTGCACAGCGTGAAGCGTATTTCAATGCATTCGGTAAATATCTGGAGCAGGCATACGGGCAGGCATT
GGCGCTGTATCACGGCCAAACTTACGATGTGGCACCAGACCAGCCTTTAGGGGATGCCAACATCGTTGCTATCCGCGTCA
CCATTCTCGATCCAAGTGGGCGTCCACCTGTCCGGTTAGATTTCCAATGGCGTAAAAATAGCCAAACCGGTAACTGGCAG
GCTTATGACATGATCGCCGAAGGGGTGAGCATGATTAGCACCAAACAGAATGAATGGGCCTCTATCCTGCGCCAAAAGGG
TGTGGATGGTTTGACCCAACAATTGCTGAGTGCGGCTAAACAGCCAATCACCTTAGATAAATAG

Upstream 100 bases:

>100_bases
TAGCCCGGCAGTAAGTGAAACGGCTCCGGCAACTGAAACTGCAGCTCCACAGGCTGCGGTACCTTCTCTTCCCGCTCAAC
ATCCTTAAGAGGGCATCTGA

Downstream 100 bases:

>100_bases
TCATTTTAGATAAATTATAGGGATAAACAGTCATTATGGCGGGTGAGCTAAGCTGGCAGTCTCTGCAGGAAACACTGGTA
CTGCAAGGTGAACTGGATCG

Product: toluene tolerance family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MFKRLFMVALLAIAPLVHAVDQSNPYRLMDEAAKKTFTRLKNEQPKIKQNPDYLRTIVREELLPFVQIKYAGALVLGSYY
KDATPAQREAYFNAFGKYLEQAYGQALALYHGQTYDVAPDQPLGDANIVAIRVTILDPSGRPPVRLDFQWRKNSQTGNWQ
AYDMIAEGVSMISTKQNEWASILRQKGVDGLTQQLLSAAKQPITLDK

Sequences:

>Translated_207_residues
MFKRLFMVALLAIAPLVHAVDQSNPYRLMDEAAKKTFTRLKNEQPKIKQNPDYLRTIVREELLPFVQIKYAGALVLGSYY
KDATPAQREAYFNAFGKYLEQAYGQALALYHGQTYDVAPDQPLGDANIVAIRVTILDPSGRPPVRLDFQWRKNSQTGNWQ
AYDMIAEGVSMISTKQNEWASILRQKGVDGLTQQLLSAAKQPITLDK
>Mature_207_residues
MFKRLFMVALLAIAPLVHAVDQSNPYRLMDEAAKKTFTRLKNEQPKIKQNPDYLRTIVREELLPFVQIKYAGALVLGSYY
KDATPAQREAYFNAFGKYLEQAYGQALALYHGQTYDVAPDQPLGDANIVAIRVTILDPSGRPPVRLDFQWRKNSQTGNWQ
AYDMIAEGVSMISTKQNEWASILRQKGVDGLTQQLLSAAKQPITLDK

Specific function: Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. May transfer phospholipid across the peripl

COG id: COG2854

COG function: function code Q; ABC-type transport system involved in resistance to organic solvents, auxiliary component

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaC/ttg2D family [H]

Homologues:

Organism=Escherichia coli, GI1789583, Length=209, Percent_Identity=77.511961722488, Blast_Score=343, Evalue=6e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023094
- InterPro:   IPR008869 [H]

Pfam domain/function: PF05494 Tol_Tol_Ttg2 [H]

EC number: NA

Molecular weight: Translated: 23409; Mature: 23409

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKRLFMVALLAIAPLVHAVDQSNPYRLMDEAAKKTFTRLKNEQPKIKQNPDYLRTIVRE
CHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
ELLPFVQIKYAGALVLGSYYKDATPAQREAYFNAFGKYLEQAYGQALALYHGQTYDVAPD
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHEEEHHCCCEECCCCC
QPLGDANIVAIRVTILDPSGRPPVRLDFQWRKNSQTGNWQAYDMIAEGVSMISTKQNEWA
CCCCCCEEEEEEEEEECCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCHHHHH
SILRQKGVDGLTQQLLSAAKQPITLDK
HHHHHCCCCHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MFKRLFMVALLAIAPLVHAVDQSNPYRLMDEAAKKTFTRLKNEQPKIKQNPDYLRTIVRE
CHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
ELLPFVQIKYAGALVLGSYYKDATPAQREAYFNAFGKYLEQAYGQALALYHGQTYDVAPD
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHEEEHHCCCEECCCCC
QPLGDANIVAIRVTILDPSGRPPVRLDFQWRKNSQTGNWQAYDMIAEGVSMISTKQNEWA
CCCCCCEEEEEEEEEECCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCHHHHH
SILRQKGVDGLTQQLLSAAKQPITLDK
HHHHHCCCCHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]