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The map label for this gene is csrD [H]

Identifier: 170022715

GI number: 170022715

Start: 504783

End: 506699

Strand: Direct

Name: csrD [H]

Synonym: YPK_0464

Alternate gene names: 170022715

Gene position: 504783-506699 (Clockwise)

Preceding gene: 170022708

Following gene: 170022716

Centisome position: 10.76

GC content: 48.36

Gene sequence:

>1917_bases
ATGCGATTTACCACCAAACTTTCTGCGTTTATGACGCTGCTGGTCGTATTGGCTATGTGTTTAGTCTTATTGGGCAGCAC
GATCAGCTTCTTCTATTTGTGCCAGAAGAAAATGGAACAACGGCTCCAAAGTATTGTGACCGCTTACGATCAGTCACTGC
TGCTGCAACCCATCAATAAAAAACGTGAATGGCTGCCACTGATGATGCAGACCCTTGGTGTGGTCGATGTCAGTGTCAAA
AATAGCACCAGTACCCTCTATCAACTCCACATTCCTGCAGTTTATACGCCTTGGAACAGCAACAGTCGTTACCGTCAGAT
GGTATTGCCTCTGTTGCATCAGCCAGGGGCGGAGATGCATTTCAACTATATTGACCCGTTGGGCAGCTATGCCCGTTCTA
TTTATGCCGCGGCCATTTTATCGCTGGTGGTGGTGGTCATTGCGTTAACGTTGTTGTTGAGTTTTCGCTGGCTACGTGAC
CAGACGGTGGGGCAGGAAAAACTTGAACGGCGAGCAAGGCGCATTCTCAATGGTGAACGTGAACATGCGGTGCGCAGCGA
GGATTACGAATGGCCACCTTGTGCCAGCAGGGCTATTGACCATTTATTATCTGAGTTGATGGAGGTGCGGGCAGAACGCA
ATCGGGTAGATACGTTAATCCGCACGTTTGCGGCTCAAGATGCTCAGACTGGCCTCAGTAACCGTCAGTTTTTTGATAAC
CAACTGACCACACAACTTGAAGAGACCGGCGCGCACGGCGTGGTCATGATGGTGCAACTGCCCGATTTTGAAGCCTTAAA
TGAAACGCATGATCAGCAGCAAGTACAGGAATTGATGAGTTCACTGGTTAACCTGCTGTCAACTTTTGTGGCCCGCTACC
CCTCAGCACTCTTGGCCCGCTACCTTAATAGTGACATCGCGATATTACTGCCCCACAAAACCCTGAAAGATGCCGATGTG
ATGGCCGCACAGTTGGTGAATGCGGTGAGAACCTTACCGGAGCCTCATATTATTGATCGCGAATCACTGTTGCATATTGG
CATCGTGGCTTACCGGAGTGGTGAGTCAGTCGAACAAATTATGGACAATGCTGGGCAGGCGACCAAAAGTGCGGCGCTGT
ATGGTGGCAACGGTTGGTATGTGTTCGACACTCAGGTACCAGAGCGCGGGCGTGGCAGTGTTAAATGGCGCACATTACTG
GAACAGACTCTGGCGAGCGGAGGCCCAAGGCTTTATCAAAAACCCGTTATTACTGTTGATGGCAAAATAAGCCATCGTGA
AATAATTAGCCGCATATATGATGGTGAGCAGGAGCTACTGGCGGCCGAGTTTATGCCCTTGGTACAATTGCTCGGATTGG
GTGAACGTTATGATCGGCAAAAGATTGATAAGATAATTCCTTTATTATCTTTATGGCCGGATGAAACGCTGGCATTTTCT
ATCAGCGTTGATTCATTATTACATCGTCCTTTCCAGCGCTGGTTGCGTGACACGCTATTACAGTGCAAAAAATCTGACCG
AATGCGAATTATCTTTGAACTTGCAGAGGCAGATGTGTGTCAACATATCGAAGAAATCCGCCAAATGGTCCGTTTATTGC
GTGGCGTAGGCTGCAAAGTGATGGCATCACAGGCTGGATTGACGGTTGTCAGCACCTCGTATATTAAGTCTTTGCAGGTT
GAAATGATAAAGCTTCATCCCGGTGTGGTAAGAAGCATTAATTTTCGCTATGAAAACCAGTTATTTGTAGAAAGTCTGAC
CGGTGCCTGTGCAGGGACGCAGACGAAAGTTTTTGCGGCAGAAGTGCGTACCCGTGAAGAATGGCAAACGCTGCAAGAGA
AAGGCGTTTACGGCGGACAGGGCAATTTCTTTGCTCCACCGACCCCATTAAACTCCGGAAAGAAAAAATATTCGTAA

Upstream 100 bases:

>100_bases
AGTAAAAAATCAGCGTTACGGGTTATTTTTGTCATATAGTACTTGCCCCCATGGATTTGAGGGACTCTATTCATTTAATT
GCACTAGGCAAGGCTAAGTA

Downstream 100 bases:

>100_bases
TAGGGCCATGTTAGCCTGATCGTTGAGCAAAAATTAACGTAGAATGTGTCAGTCATTACCGTGAATCGTTGGTGTGCACT
TACTTTCAACGAGAATCAGG

Product: regulatory protein CsrD

Products: NA

Alternate protein names: Regulator of CsrB and CsrC decay CsrD [H]

Number of amino acids: Translated: 638; Mature: 638

Protein sequence:

>638_residues
MRFTTKLSAFMTLLVVLAMCLVLLGSTISFFYLCQKKMEQRLQSIVTAYDQSLLLQPINKKREWLPLMMQTLGVVDVSVK
NSTSTLYQLHIPAVYTPWNSNSRYRQMVLPLLHQPGAEMHFNYIDPLGSYARSIYAAAILSLVVVVIALTLLLSFRWLRD
QTVGQEKLERRARRILNGEREHAVRSEDYEWPPCASRAIDHLLSELMEVRAERNRVDTLIRTFAAQDAQTGLSNRQFFDN
QLTTQLEETGAHGVVMMVQLPDFEALNETHDQQQVQELMSSLVNLLSTFVARYPSALLARYLNSDIAILLPHKTLKDADV
MAAQLVNAVRTLPEPHIIDRESLLHIGIVAYRSGESVEQIMDNAGQATKSAALYGGNGWYVFDTQVPERGRGSVKWRTLL
EQTLASGGPRLYQKPVITVDGKISHREIISRIYDGEQELLAAEFMPLVQLLGLGERYDRQKIDKIIPLLSLWPDETLAFS
ISVDSLLHRPFQRWLRDTLLQCKKSDRMRIIFELAEADVCQHIEEIRQMVRLLRGVGCKVMASQAGLTVVSTSYIKSLQV
EMIKLHPGVVRSINFRYENQLFVESLTGACAGTQTKVFAAEVRTREEWQTLQEKGVYGGQGNFFAPPTPLNSGKKKYS

Sequences:

>Translated_638_residues
MRFTTKLSAFMTLLVVLAMCLVLLGSTISFFYLCQKKMEQRLQSIVTAYDQSLLLQPINKKREWLPLMMQTLGVVDVSVK
NSTSTLYQLHIPAVYTPWNSNSRYRQMVLPLLHQPGAEMHFNYIDPLGSYARSIYAAAILSLVVVVIALTLLLSFRWLRD
QTVGQEKLERRARRILNGEREHAVRSEDYEWPPCASRAIDHLLSELMEVRAERNRVDTLIRTFAAQDAQTGLSNRQFFDN
QLTTQLEETGAHGVVMMVQLPDFEALNETHDQQQVQELMSSLVNLLSTFVARYPSALLARYLNSDIAILLPHKTLKDADV
MAAQLVNAVRTLPEPHIIDRESLLHIGIVAYRSGESVEQIMDNAGQATKSAALYGGNGWYVFDTQVPERGRGSVKWRTLL
EQTLASGGPRLYQKPVITVDGKISHREIISRIYDGEQELLAAEFMPLVQLLGLGERYDRQKIDKIIPLLSLWPDETLAFS
ISVDSLLHRPFQRWLRDTLLQCKKSDRMRIIFELAEADVCQHIEEIRQMVRLLRGVGCKVMASQAGLTVVSTSYIKSLQV
EMIKLHPGVVRSINFRYENQLFVESLTGACAGTQTKVFAAEVRTREEWQTLQEKGVYGGQGNFFAPPTPLNSGKKKYS
>Mature_638_residues
MRFTTKLSAFMTLLVVLAMCLVLLGSTISFFYLCQKKMEQRLQSIVTAYDQSLLLQPINKKREWLPLMMQTLGVVDVSVK
NSTSTLYQLHIPAVYTPWNSNSRYRQMVLPLLHQPGAEMHFNYIDPLGSYARSIYAAAILSLVVVVIALTLLLSFRWLRD
QTVGQEKLERRARRILNGEREHAVRSEDYEWPPCASRAIDHLLSELMEVRAERNRVDTLIRTFAAQDAQTGLSNRQFFDN
QLTTQLEETGAHGVVMMVQLPDFEALNETHDQQQVQELMSSLVNLLSTFVARYPSALLARYLNSDIAILLPHKTLKDADV
MAAQLVNAVRTLPEPHIIDRESLLHIGIVAYRSGESVEQIMDNAGQATKSAALYGGNGWYVFDTQVPERGRGSVKWRTLL
EQTLASGGPRLYQKPVITVDGKISHREIISRIYDGEQELLAAEFMPLVQLLGLGERYDRQKIDKIIPLLSLWPDETLAFS
ISVDSLLHRPFQRWLRDTLLQCKKSDRMRIIFELAEADVCQHIEEIRQMVRLLRGVGCKVMASQAGLTVVSTSYIKSLQV
EMIKLHPGVVRSINFRYENQLFVESLTGACAGTQTKVFAAEVRTREEWQTLQEKGVYGGQGNFFAPPTPLNSGKKKYS

Specific function: Serves as a specificity factor required for RNase E- mediated decay of the small global regulatory RNAs CsrB and CsrC, it is probably not a nuclease. Nor does its activity involve c-di- GMP, despite its domain composition. Positively modulates motility ge

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1789650, Length=641, Percent_Identity=50.7020280811232, Blast_Score=676, Evalue=0.0,
Organism=Escherichia coli, GI87081921, Length=440, Percent_Identity=22.5, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787541, Length=433, Percent_Identity=21.2471131639723, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 72364; Mature: 72364

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFTTKLSAFMTLLVVLAMCLVLLGSTISFFYLCQKKMEQRLQSIVTAYDQSLLLQPINK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KREWLPLMMQTLGVVDVSVKNSTSTLYQLHIPAVYTPWNSNSRYRQMVLPLLHQPGAEMH
HHHHHHHHHHHHCCEEEEECCCCCEEEEEEECEEECCCCCCHHHHHHHHHHHHCCCCCCC
FNYIDPLGSYARSIYAAAILSLVVVVIALTLLLSFRWLRDQTVGQEKLERRARRILNGER
CCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCH
EHAVRSEDYEWPPCASRAIDHLLSELMEVRAERNRVDTLIRTFAAQDAQTGLSNRQFFDN
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
QLTTQLEETGAHGVVMMVQLPDFEALNETHDQQQVQELMSSLVNLLSTFVARYPSALLAR
HHHHHHHHCCCCCEEEEEECCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLNSDIAILLPHKTLKDADVMAAQLVNAVRTLPEPHIIDRESLLHIGIVAYRSGESVEQI
HHCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHEEEECCCCHHHHH
MDNAGQATKSAALYGGNGWYVFDTQVPERGRGSVKWRTLLEQTLASGGPRLYQKPVITVD
HHCCCCHHHCCEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEC
GKISHREIISRIYDGEQELLAAEFMPLVQLLGLGERYDRQKIDKIIPLLSLWPDETLAFS
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEE
ISVDSLLHRPFQRWLRDTLLQCKKSDRMRIIFELAEADVCQHIEEIRQMVRLLRGVGCKV
EEHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
MASQAGLTVVSTSYIKSLQVEMIKLHPGVVRSINFRYENQLFVESLTGACAGTQTKVFAA
ECCCCCCCEEHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHH
EVRTREEWQTLQEKGVYGGQGNFFAPPTPLNSGKKKYS
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRFTTKLSAFMTLLVVLAMCLVLLGSTISFFYLCQKKMEQRLQSIVTAYDQSLLLQPINK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KREWLPLMMQTLGVVDVSVKNSTSTLYQLHIPAVYTPWNSNSRYRQMVLPLLHQPGAEMH
HHHHHHHHHHHHCCEEEEECCCCCEEEEEEECEEECCCCCCHHHHHHHHHHHHCCCCCCC
FNYIDPLGSYARSIYAAAILSLVVVVIALTLLLSFRWLRDQTVGQEKLERRARRILNGER
CCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCH
EHAVRSEDYEWPPCASRAIDHLLSELMEVRAERNRVDTLIRTFAAQDAQTGLSNRQFFDN
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
QLTTQLEETGAHGVVMMVQLPDFEALNETHDQQQVQELMSSLVNLLSTFVARYPSALLAR
HHHHHHHHCCCCCEEEEEECCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLNSDIAILLPHKTLKDADVMAAQLVNAVRTLPEPHIIDRESLLHIGIVAYRSGESVEQI
HHCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHEEEECCCCHHHHH
MDNAGQATKSAALYGGNGWYVFDTQVPERGRGSVKWRTLLEQTLASGGPRLYQKPVITVD
HHCCCCHHHCCEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEC
GKISHREIISRIYDGEQELLAAEFMPLVQLLGLGERYDRQKIDKIIPLLSLWPDETLAFS
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEEEE
ISVDSLLHRPFQRWLRDTLLQCKKSDRMRIIFELAEADVCQHIEEIRQMVRLLRGVGCKV
EEHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
MASQAGLTVVSTSYIKSLQVEMIKLHPGVVRSINFRYENQLFVESLTGACAGTQTKVFAA
ECCCCCCCEEHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHH
EVRTREEWQTLQEKGVYGGQGNFFAPPTPLNSGKKKYS
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 3049542 [H]