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The map label for this gene is zntR [H]

Identifier: 170022571

GI number: 170022571

Start: 333471

End: 333896

Strand: Direct

Name: zntR [H]

Synonym: YPK_0310

Alternate gene names: 170022571

Gene position: 333471-333896 (Clockwise)

Preceding gene: 170022570

Following gene: 170022572

Centisome position: 7.11

GC content: 45.31

Gene sequence:

>426_bases
ATGTTAAAAATCGGGCAGTTAGCTAAACTTGCTGATGTAACGCCGGATACTATCCGTTACTACGAAAAGCAGGGAATGAT
GGATCACGGTGAACGAACTGATGGTGGCTACCGGCTGTATACTGATCAGGACCTTCAGCGTTTACGGTTTATCCGCTACG
CCAAGCAACTAGGCTTTACATTGGATACTATCGCAGAATTATTGTCGATCCGGATAGATCCTGACCATCATACCTGCCAG
GAGTCCAAGTCTATTGTAGATTCACGGCTTAGTGATGTGGAAGGTAAGATCAGAGAATTAGAGAGAATGCGTGATTCCCT
AAAAAGACTCAGCGAGGCTTGTTGTGGCACTAGTCATGCGACGACATACTGCTCAATATTGGAAGCTTTGGAGCAGGGGG
CAACAGAAGAGTTAATTAAGGTATGA

Upstream 100 bases:

>100_bases
ATGAGATTTTTTCTTAATGAGGTCTGTAACATGATGACTTCCAACTCCTTATTTTATACGCTGTTGATTATCAACAGGAA
TTGGCTGGTAGGTGGACAAT

Downstream 100 bases:

>100_bases
ATTTCTCTACAGAGGGTTTAAATCGGCAGAGGACCACCGTATTATGTTCAGGATTTATCCATAGCGTCATTACTACGAGG
TAGCACCATGACAACATATC

Product: zinc-responsive transcriptional regulator

Products: NA

Alternate protein names: Zn(II)-responsive regulator of zntA [H]

Number of amino acids: Translated: 141; Mature: 141

Protein sequence:

>141_residues
MLKIGQLAKLADVTPDTIRYYEKQGMMDHGERTDGGYRLYTDQDLQRLRFIRYAKQLGFTLDTIAELLSIRIDPDHHTCQ
ESKSIVDSRLSDVEGKIRELERMRDSLKRLSEACCGTSHATTYCSILEALEQGATEELIKV

Sequences:

>Translated_141_residues
MLKIGQLAKLADVTPDTIRYYEKQGMMDHGERTDGGYRLYTDQDLQRLRFIRYAKQLGFTLDTIAELLSIRIDPDHHTCQ
ESKSIVDSRLSDVEGKIRELERMRDSLKRLSEACCGTSHATTYCSILEALEQGATEELIKV
>Mature_141_residues
MLKIGQLAKLADVTPDTIRYYEKQGMMDHGERTDGGYRLYTDQDLQRLRFIRYAKQLGFTLDTIAELLSIRIDPDHHTCQ
ESKSIVDSRLSDVEGKIRELERMRDSLKRLSEACCGTSHATTYCSILEALEQGATEELIKV

Specific function: Zinc-responsive transcriptional regulator of zntA [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789687, Length=135, Percent_Identity=69.6296296296296, Blast_Score=208, Evalue=9e-56,
Organism=Escherichia coli, GI1786695, Length=129, Percent_Identity=35.6589147286822, Blast_Score=89, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358
- InterPro:   IPR011788 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 16129; Mature: 16129

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKIGQLAKLADVTPDTIRYYEKQGMMDHGERTDGGYRLYTDQDLQRLRFIRYAKQLGFT
CCCCHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCC
LDTIAELLSIRIDPDHHTCQESKSIVDSRLSDVEGKIRELERMRDSLKRLSEACCGTSHA
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
TTYCSILEALEQGATEELIKV
HHHHHHHHHHHHCCHHHHHCC
>Mature Secondary Structure
MLKIGQLAKLADVTPDTIRYYEKQGMMDHGERTDGGYRLYTDQDLQRLRFIRYAKQLGFT
CCCCHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCC
LDTIAELLSIRIDPDHHTCQESKSIVDSRLSDVEGKIRELERMRDSLKRLSEACCGTSHA
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
TTYCSILEALEQGATEELIKV
HHHHHHHHHHHHCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]