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The map label for this gene is secY [H]

Identifier: 170022564

GI number: 170022564

Start: 328537

End: 329868

Strand: Direct

Name: secY [H]

Synonym: YPK_0303

Alternate gene names: 170022564

Gene position: 328537-329868 (Clockwise)

Preceding gene: 170022563

Following gene: 170022565

Centisome position: 7.01

GC content: 46.02

Gene sequence:

>1332_bases
ATGGCTAAGCAACCAGGATTAGATTTTCAAAGTGCTAAAGGCGGATTAGGCGAGCTGAAGCGCAGACTTTTGTTTGTTAT
CGGTGCGCTTATTGTTTTCCGTATCGGCTCTTTTATTCCGATTCCTGGTATCGATGCCACTGTGCTTGCCAAATTGCTTG
AGCAGCAGAGAGGCACCATCATTGAAATGTTTAACATGTTTTCTGGTGGTGCTCTCAGTCGTGCTTCTATCTTTGCCTTG
GGTATCATGCCGTATATTTCGGCATCAATTATTATCCAACTGTTAACGGTGGTACATCCAGCGTTAGCAGAAATAAAGAA
AGAAGGGGAAGCTGGCCGTCGTAAGATTAGCCAGTACACCCGTTATGGCACGTTGGTATTGGCTATATTCCAATCGATCG
GTATTGCTACCGGTCTTCCGAATATGCCTGGGATGCAAGGTCTGGTAATCAATCCAGGCTTTGCTTTCTATTTTACCGCT
GTTGTTAGCTTAGTCACAGGGACTATGTTCCTGATGTGGCTGGGTGAACAGATTACTGAACGGGGTATCGGAAACGGTAT
TTCAATCATAATCTTTGCTGGTATTGTTGCGGGGCTTCCTCCTGCAATTGCCCATACCATCGAGCAAGCTCGGCAAGGCG
ACCTGCACTTCCTCCTGTTGCTGTTGGTTGCAGTATTAGTGTTTGCAGTAACCTTCTTCGTTGTTTTCATTGAACGTGGT
CAACGTCGTATTGTCGTTAACTATGCAAAACGTCAACAAGGTCGTCGTGTTTATGCAGCACAGAGCACACACTTACCGTT
GAAAGTGAATATGGCTGGGGTTATCCCTGCAATCTTCGCTTCCAGCATAATTCTGTTTCCTGCCACGATTGCATCATGGT
TTGGGGGCGGAACAGGTTGGAACTGGCTGACGACTATTTCGATGTATTTGCAGCCGGGACAGCCGCTTTATGTGTTACTC
TATGCGTCTGCAATCATCTTCTTCTGTTTCTTCTACACGGCGTTAGTGTTCAACCCGCGTGAAACAGCAGATAACCTGAA
GAAGTCCGGTGCATTCGTGCCAGGAATTCGTCCGGGAGAGCAAACGGCGAAGTACATCGATAAAGTAATGACACGTCTAA
CCTTAATTGGTGCGATGTATATTACTTTCATCTGCCTGATCCCGGAGTTCATGCGTGACGCGATGAAAGTACCATTTTAC
TTTGGTGGTACCTCCCTACTTATTGTAGTGGTGGTCATCATGGACTTTATGGCTCAAGTGCAAACTCTGATGATGTCTAG
TCAGTACGAGTCTGCATTGAAGAAAGCAAACCTGAAAGGCTATAACCGCTAA

Upstream 100 bases:

>100_bases
GAAGTCAATCGTGCGGTAACTCTTCGTGGTCTGCGAGTCACCAAAGGCGCTCGTGCTGCTATCGAAGCTGCTGGCGGTAA
AATTGAGGAATAAGTAGCAG

Downstream 100 bases:

>100_bases
TCAGGGATGTTTGAGAAGTTACGGAGAGTAAAAATGAAAGTTCGTGCTTCCGTCAAGAAATTATGTCGTAACTGCAAAAT
TGTTAAGCGTAACGGTGTCG

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MAKQPGLDFQSAKGGLGELKRRLLFVIGALIVFRIGSFIPIPGIDATVLAKLLEQQRGTIIEMFNMFSGGALSRASIFAL
GIMPYISASIIIQLLTVVHPALAEIKKEGEAGRRKISQYTRYGTLVLAIFQSIGIATGLPNMPGMQGLVINPGFAFYFTA
VVSLVTGTMFLMWLGEQITERGIGNGISIIIFAGIVAGLPPAIAHTIEQARQGDLHFLLLLLVAVLVFAVTFFVVFIERG
QRRIVVNYAKRQQGRRVYAAQSTHLPLKVNMAGVIPAIFASSIILFPATIASWFGGGTGWNWLTTISMYLQPGQPLYVLL
YASAIIFFCFFYTALVFNPRETADNLKKSGAFVPGIRPGEQTAKYIDKVMTRLTLIGAMYITFICLIPEFMRDAMKVPFY
FGGTSLLIVVVVIMDFMAQVQTLMMSSQYESALKKANLKGYNR

Sequences:

>Translated_443_residues
MAKQPGLDFQSAKGGLGELKRRLLFVIGALIVFRIGSFIPIPGIDATVLAKLLEQQRGTIIEMFNMFSGGALSRASIFAL
GIMPYISASIIIQLLTVVHPALAEIKKEGEAGRRKISQYTRYGTLVLAIFQSIGIATGLPNMPGMQGLVINPGFAFYFTA
VVSLVTGTMFLMWLGEQITERGIGNGISIIIFAGIVAGLPPAIAHTIEQARQGDLHFLLLLLVAVLVFAVTFFVVFIERG
QRRIVVNYAKRQQGRRVYAAQSTHLPLKVNMAGVIPAIFASSIILFPATIASWFGGGTGWNWLTTISMYLQPGQPLYVLL
YASAIIFFCFFYTALVFNPRETADNLKKSGAFVPGIRPGEQTAKYIDKVMTRLTLIGAMYITFICLIPEFMRDAMKVPFY
FGGTSLLIVVVVIMDFMAQVQTLMMSSQYESALKKANLKGYNR
>Mature_442_residues
AKQPGLDFQSAKGGLGELKRRLLFVIGALIVFRIGSFIPIPGIDATVLAKLLEQQRGTIIEMFNMFSGGALSRASIFALG
IMPYISASIIIQLLTVVHPALAEIKKEGEAGRRKISQYTRYGTLVLAIFQSIGIATGLPNMPGMQGLVINPGFAFYFTAV
VSLVTGTMFLMWLGEQITERGIGNGISIIIFAGIVAGLPPAIAHTIEQARQGDLHFLLLLLVAVLVFAVTFFVVFIERGQ
RRIVVNYAKRQQGRRVYAAQSTHLPLKVNMAGVIPAIFASSIILFPATIASWFGGGTGWNWLTTISMYLQPGQPLYVLLY
ASAIIFFCFFYTALVFNPRETADNLKKSGAFVPGIRPGEQTAKYIDKVMTRLTLIGAMYITFICLIPEFMRDAMKVPFYF
GGTSLLIVVVVIMDFMAQVQTLMMSSQYESALKKANLKGYNR

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel [H]

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family [H]

Homologues:

Organism=Escherichia coli, GI1789696, Length=443, Percent_Identity=97.9683972911964, Blast_Score=811, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002208
- InterPro:   IPR023201 [H]

Pfam domain/function: PF00344 SecY [H]

EC number: NA

Molecular weight: Translated: 48632; Mature: 48501

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: PS00755 SECY_1 ; PS00756 SECY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AKQPGLDFQSAKGGLGELKRRLLFVIGALIVFRIGSFIPIPGIDATVLAKLLEQQRGTI
CCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHH
IEMFNMFSGGALSRASIFALGIMPYISASIIIQLLTVVHPALAEIKKEGEAGRRKISQYT
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
RYGTLVLAIFQSIGIATGLPNMPGMQGLVINPGFAFYFTAVVSLVTGTMFLMWLGEQITE
HHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGIGNGISIIIFAGIVAGLPPAIAHTIEQARQGDLHFLLLLLVAVLVFAVTFFVVFIERG
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
QRRIVVNYAKRQQGRRVYAAQSTHLPLKVNMAGVIPAIFASSIILFPATIASWFGGGTGW
CCEEEEEHHHHHCCCEEEEECCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
NWLTTISMYLQPGQPLYVLLYASAIIFFCFFYTALVFNPRETADNLKKSGAFVPGIRPGE
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCH
QTAKYIDKVMTRLTLIGAMYITFICLIPEFMRDAMKVPFYFGGTSLLIVVVVIMDFMAQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCHHHHHHHHHHHHHHHHH
QTLMMSSQYESALKKANLKGYNR
HHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]