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The map label for this gene is lytA [H]

Identifier: 169833684

GI number: 169833684

Start: 452082

End: 453104

Strand: Direct

Name: lytA [H]

Synonym: SPH_0501

Alternate gene names: 169833684

Gene position: 452082-453104 (Clockwise)

Preceding gene: 169834068

Following gene: 169833737

Centisome position: 20.13

GC content: 40.57

Gene sequence:

>1023_bases
ATGAAGCTTTTGAAAAAAATGATGCAAGTCGCACTAGCCACATTTTTCTTCGGTTTGCTAGGGACCAGTACAGTATTTGC
AGATGATTCTGAAGGATGGCAGTTTGTCCAAGAAAATGGTAGAACCTACTACAAAAAGGGGGATCTAAAAGAAACCTACT
GGAGAGTGATAGATGGGAAGTACTATTATTTTGATCCTTTATCCGGAGAGATGGTTGTCGGCTGGCAATATATACCTGCT
CCACACAAGGGGGTTACGATTGGTCCTTCTCCAAGAATAGAGATTGCTCTTAGACCAGATTGGTTTTATTTTGGTCAAGA
TGGTGTCTTACAAGAATTTGTTGGCAAGCAAGTTTTAGAAGCAAAAACTGCTACGAATACCAACAAACATCATGGGGAAG
AATATGATAGCCCAGCAGAGAAACGAGTCTATTATTTTGAAGATCAGCGTAGTTATCATACTTTAAAAACTGGTTGGATT
TATGAAGAGGGTCATTGGTATTATTTACAGAAGGATGGTGGCTTTGATTCGCGCATCAACAGATTGACGGTTGGAGAGCT
AGCACGTGGTTGGGTTAAGGATTACCCTCTTACCTATGATGAAGAGAAGCTAAAAGCAGCTCCATGGTACTATCTAGATC
CAACAACTGGCATTATGCAAACTGGTTGGCAACATCTTGGTAATAAATGGTACTATCTCCGTTCATCAGGAGCTATGGCA
ACTGGCTGGTATCAAGATGGTTCAACTTGGTACTATTTAGATGCTGAAAATGGCGATATGAAAACTGGTTGGCAAAACCT
TGGGAACAAATGGTACTATCTCCGTTCATCAGGAGCTATGGCAACTGGTTGGTATCAGGAAGGTTCGACTTGGTACTATC
TAAATGCAAGTAATGGAGATATGAAAACAGGCTGGTTCCAAGTCAATGGTAACTGGTACTATGCCTATGATTCAGGTGCT
TTAGCTGTTAATACCACAGTAGGTGGTTACTACTTAAACTATAATGGTGAATGGGTTAAGTAA

Upstream 100 bases:

>100_bases
TTCAAATGGAGCAATGGTTACAGGTAGCCAAACTATCGATGGTAAAGTTTATAACTTCGCTTCATCTGGTGAGTGGATTT
AATGTTGGAGGATATATAAA

Downstream 100 bases:

>100_bases
TGAAGGCTAATTGTAAACTGTGATGGATACTTAACTTTGTATAATAGGTGGATAAAAGTCTTCACAATCAAAAAACGCAT
AGTATCAGGTGTTGAATATG

Product: choline binding protein F

Products: NA

Alternate protein names: Cell wall hydrolase; Mucopeptide aminohydrolase; Murein hydrolase; N-acetylmuramoyl-L-alanine amidase [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MKLLKKMMQVALATFFFGLLGTSTVFADDSEGWQFVQENGRTYYKKGDLKETYWRVIDGKYYYFDPLSGEMVVGWQYIPA
PHKGVTIGPSPRIEIALRPDWFYFGQDGVLQEFVGKQVLEAKTATNTNKHHGEEYDSPAEKRVYYFEDQRSYHTLKTGWI
YEEGHWYYLQKDGGFDSRINRLTVGELARGWVKDYPLTYDEEKLKAAPWYYLDPTTGIMQTGWQHLGNKWYYLRSSGAMA
TGWYQDGSTWYYLDAENGDMKTGWQNLGNKWYYLRSSGAMATGWYQEGSTWYYLNASNGDMKTGWFQVNGNWYYAYDSGA
LAVNTTVGGYYLNYNGEWVK

Sequences:

>Translated_340_residues
MKLLKKMMQVALATFFFGLLGTSTVFADDSEGWQFVQENGRTYYKKGDLKETYWRVIDGKYYYFDPLSGEMVVGWQYIPA
PHKGVTIGPSPRIEIALRPDWFYFGQDGVLQEFVGKQVLEAKTATNTNKHHGEEYDSPAEKRVYYFEDQRSYHTLKTGWI
YEEGHWYYLQKDGGFDSRINRLTVGELARGWVKDYPLTYDEEKLKAAPWYYLDPTTGIMQTGWQHLGNKWYYLRSSGAMA
TGWYQDGSTWYYLDAENGDMKTGWQNLGNKWYYLRSSGAMATGWYQEGSTWYYLNASNGDMKTGWFQVNGNWYYAYDSGA
LAVNTTVGGYYLNYNGEWVK
>Mature_340_residues
MKLLKKMMQVALATFFFGLLGTSTVFADDSEGWQFVQENGRTYYKKGDLKETYWRVIDGKYYYFDPLSGEMVVGWQYIPA
PHKGVTIGPSPRIEIALRPDWFYFGQDGVLQEFVGKQVLEAKTATNTNKHHGEEYDSPAEKRVYYFEDQRSYHTLKTGWI
YEEGHWYYLQKDGGFDSRINRLTVGELARGWVKDYPLTYDEEKLKAAPWYYLDPTTGIMQTGWQHLGNKWYYLRSSGAMA
TGWYQDGSTWYYLDAENGDMKTGWQNLGNKWYYLRSSGAMATGWYQEGSTWYYLNASNGDMKTGWFQVNGNWYYAYDSGA
LAVNTTVGGYYLNYNGEWVK

Specific function: Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transformation, formation of the flagella and sporulation. Autolysin strictly depends on the presence of choline-containing

COG id: COG5263

COG function: function code R; FOG: Glucan-binding domain (YG repeat)

Gene ontology:

Cell location: Secreted (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 6 cell wall-binding repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002502
- InterPro:   IPR018337 [H]

Pfam domain/function: PF01510 Amidase_2; PF01473 CW_binding_1 [H]

EC number: =3.5.1.28 [H]

Molecular weight: Translated: 39618; Mature: 39618

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLKKMMQVALATFFFGLLGTSTVFADDSEGWQFVQENGRTYYKKGDLKETYWRVIDGK
CHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHCCCEEEECCCCHHHHHEEECCE
YYYFDPLSGEMVVGWQYIPAPHKGVTIGPSPRIEIALRPDWFYFGQDGVLQEFVGKQVLE
EEEECCCCCCEEEEEEECCCCCCCEEECCCCCEEEEECCCEEEECCCCHHHHHHHHHHHH
AKTATNTNKHHGEEYDSPAEKRVYYFEDQRSYHTLKTGWIYEEGHWYYLQKDGGFDSRIN
HHHCCCCCCCCCCCCCCCHHCEEEEEECCCCEEEEEECEEEECCEEEEEEECCCCHHHHC
RLTVGELARGWVKDYPLTYDEEKLKAAPWYYLDPTTGIMQTGWQHLGNKWYYLRSSGAMA
EEEHHHHHHHHHHCCCCCCCHHHHCCCCEEEECCCCHHHHHHHHHHCCEEEEEECCCCEE
TGWYQDGSTWYYLDAENGDMKTGWQNLGNKWYYLRSSGAMATGWYQEGSTWYYLNASNGD
EEEEECCCEEEEEECCCCCCCCCHHHCCCEEEEEECCCCEEEEEEECCCEEEEEECCCCC
MKTGWFQVNGNWYYAYDSGALAVNTTVGGYYLNYNGEWVK
CEEEEEEECCEEEEEECCCCEEEEEEECEEEEECCCCEEC
>Mature Secondary Structure
MKLLKKMMQVALATFFFGLLGTSTVFADDSEGWQFVQENGRTYYKKGDLKETYWRVIDGK
CHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHCCCEEEECCCCHHHHHEEECCE
YYYFDPLSGEMVVGWQYIPAPHKGVTIGPSPRIEIALRPDWFYFGQDGVLQEFVGKQVLE
EEEECCCCCCEEEEEEECCCCCCCEEECCCCCEEEEECCCEEEECCCCHHHHHHHHHHHH
AKTATNTNKHHGEEYDSPAEKRVYYFEDQRSYHTLKTGWIYEEGHWYYLQKDGGFDSRIN
HHHCCCCCCCCCCCCCCCHHCEEEEEECCCCEEEEEECEEEECCEEEEEEECCCCHHHHC
RLTVGELARGWVKDYPLTYDEEKLKAAPWYYLDPTTGIMQTGWQHLGNKWYYLRSSGAMA
EEEHHHHHHHHHHCCCCCCCHHHHCCCCEEEECCCCHHHHHHHHHHCCEEEEEECCCCEE
TGWYQDGSTWYYLDAENGDMKTGWQNLGNKWYYLRSSGAMATGWYQEGSTWYYLNASNGD
EEEEECCCEEEEEECCCCCCCCCHHHCCCEEEEEECCCCEEEEEEECCCEEEEEECCCCC
MKTGWFQVNGNWYYAYDSGALAVNTTVGGYYLNYNGEWVK
CEEEEEEECCEEEEEECCCCEEEEEEECEEEEECCCCEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2875013; 11463916 [H]