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The map label for this gene is efp

Identifier: 169824232

GI number: 169824232

Start: 595911

End: 596468

Strand: Direct

Name: efp

Synonym: FMG_0535

Alternate gene names: 169824232

Gene position: 595911-596468 (Clockwise)

Preceding gene: 169824231

Following gene: 169824233

Centisome position: 33.15

GC content: 32.97

Gene sequence:

>558_bases
ATGATACAAGCAGGAGATTTTAGAAAAGGCACAACTTTTGAAATGGATGGAGATGTATGGCAAATTATAGATTTCCAACA
CGTTAAACCAGGTAAAGGTGCAGCTTTTGTAAGAACAAAAATCAGATCAGTTATGACTGGTTCAAACAGAGACATGACTT
TCAATCCTAACGAAAAATATGAAGAAGCTAGAATTGAAACAAGAGAAATGCAATACTTATACAACGACGGAACTTTATAT
TATTTCATGGACCCAGATTCTTATGAACAATTACCAATTGATAAAGCTAGTGTAGAAGAAGCTATTCTTTACATAAAGGA
AAATGATATGGCAACAATTAAATTTTTCAAAGGTAAAGCATTCCAAGTTTCTCCACCAAACTTTGTTGAGTTAGAAATCA
CTCAAACAGAACCTGGAATTAAAGGTAACACTGCAACAGGAGCTACAAAACCAGCCACTGTAGAAACAGGAGCTACAGTT
AATGTACCTTTATTTGTAAATGAAGGAGATAAAATTAAAATAGATACAAGAACTGGAGAATATTTATCAAGAGTTTAG

Upstream 100 bases:

>100_bases
GAAAATTTTACAAGGCGATGCATCAGAATGTGCGAGAAAATAGTTGTTCATAATTAATTAGTAATGTATAATATATGATA
GATAATTGTAGGAGGTATAT

Downstream 100 bases:

>100_bases
TATTTGTTGACTTTTCAACGCGTTTATGATAAAGTAGTACGGTGGATTTTGTCCATACTAATAGAGGAGGTCTAATATGA
GAGATAAAGTAATTTTAGAA

Product: translation elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MIQAGDFRKGTTFEMDGDVWQIIDFQHVKPGKGAAFVRTKIRSVMTGSNRDMTFNPNEKYEEARIETREMQYLYNDGTLY
YFMDPDSYEQLPIDKASVEEAILYIKENDMATIKFFKGKAFQVSPPNFVELEITQTEPGIKGNTATGATKPATVETGATV
NVPLFVNEGDKIKIDTRTGEYLSRV

Sequences:

>Translated_185_residues
MIQAGDFRKGTTFEMDGDVWQIIDFQHVKPGKGAAFVRTKIRSVMTGSNRDMTFNPNEKYEEARIETREMQYLYNDGTLY
YFMDPDSYEQLPIDKASVEEAILYIKENDMATIKFFKGKAFQVSPPNFVELEITQTEPGIKGNTATGATKPATVETGATV
NVPLFVNEGDKIKIDTRTGEYLSRV
>Mature_185_residues
MIQAGDFRKGTTFEMDGDVWQIIDFQHVKPGKGAAFVRTKIRSVMTGSNRDMTFNPNEKYEEARIETREMQYLYNDGTLY
YFMDPDSYEQLPIDKASVEEAILYIKENDMATIKFFKGKAFQVSPPNFVELEITQTEPGIKGNTATGATKPATVETGATV
NVPLFVNEGDKIKIDTRTGEYLSRV

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=182, Percent_Identity=42.8571428571429, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI87082061, Length=188, Percent_Identity=29.2553191489362, Blast_Score=95, Evalue=3e-21,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_FINM2 (B0S053)

Other databases:

- EMBL:   AP008971
- RefSeq:   YP_001691843.1
- ProteinModelPortal:   B0S053
- SMR:   B0S053
- GeneID:   6019809
- GenomeReviews:   AP008971_GR
- KEGG:   fma:FMG_0535
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- BioCyc:   FMAG334413:FMG_0535-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20920; Mature: 20920

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQAGDFRKGTTFEMDGDVWQIIDFQHVKPGKGAAFVRTKIRSVMTGSNRDMTFNPNEKY
CCCCCCCCCCCEEEECCCEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCH
EEARIETREMQYLYNDGTLYYFMDPDSYEQLPIDKASVEEAILYIKENDMATIKFFKGKA
HHHHCCCEEEEEEEECCEEEEEECCCCCCCCCCCHHCCCEEEEEEECCCEEEEEEECCCE
FQVSPPNFVELEITQTEPGIKGNTATGATKPATVETGATVNVPLFVNEGDKIKIDTRTGE
EEECCCCEEEEEEECCCCCCCCCCCCCCCCCCEEECCCEEEEEEEECCCCEEEEECCCCH
YLSRV
HHHCC
>Mature Secondary Structure
MIQAGDFRKGTTFEMDGDVWQIIDFQHVKPGKGAAFVRTKIRSVMTGSNRDMTFNPNEKY
CCCCCCCCCCCEEEECCCEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCH
EEARIETREMQYLYNDGTLYYFMDPDSYEQLPIDKASVEEAILYIKENDMATIKFFKGKA
HHHHCCCEEEEEEEECCEEEEEECCCCCCCCCCCHHCCCEEEEEEECCCEEEEEEECCCE
FQVSPPNFVELEITQTEPGIKGNTATGATKPATVETGATVNVPLFVNEGDKIKIDTRTGE
EEECCCCEEEEEEECCCCCCCCCCCCCCCCCCEEECCCEEEEEEEECCCCEEEEECCCCH
YLSRV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA