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The map label for this gene is pfp [H]

Identifier: 169824183

GI number: 169824183

Start: 546170

End: 547297

Strand: Direct

Name: pfp [H]

Synonym: FMG_0486

Alternate gene names: 169824183

Gene position: 546170-547297 (Clockwise)

Preceding gene: 169824182

Following gene: 169824184

Centisome position: 30.38

GC content: 33.51

Gene sequence:

>1128_bases
TTGGGATTTGACAATGTGTACGGAGCTTTATACGGAGTACAAGGATTATTGGATTCCAAAATCATAGACTTGAAGTCGCA
AATCAAAACAGATAAAGATTTGAACAGATTAAAAATCACTCCTGCAAGTGCATTGGGTTCTTGCAGATACAAAGTAGATA
GCGAAGAGAAACTTGCCAAAATCGTAGAAATTTTGAAATCATTTAATATTAATTATTTTATCTACATTGGTGGCAATGAT
TCAATGGACACTGTGTATCAATTATCCAAATACATCGAAAAAATTGGAGAAGATATTAATGTAATGGGATCTCCAAAAAC
AATTGACAATGATTTGTTTGGAACAGATCACACTCCAGGGTTTGGTTCTGCAGCAAAATTTGTGGCGAATTCTGTTTATG
AAATAGCAAAGGATGTCGAAATCTACGACTATAGAACGATAACTATTGTAGAAATTATGGGACGATACGCTGGATGGTTA
ACAGCAGCAGGAGCAATCTCCAAGAAACTTTGCAATCTTGGAGCAGATCTTGTGTATATAAGTGAAGATACATTTGAATT
TGATAACCTAGTCAAGGAAATCAATGAAAACTTCAAAAGGACAGATAATATTTTGATTTTAGTAAGTGAAGGTATTAAAG
ATTCTTCAAATAACTTCATATCCAAAACATCTGGCAAGAAAGACAAGTTCGGCCATGCACAATTGCAAGGACCATCGCAC
ATAATCAGAGATAAATTAAAAGAAATTTACGATATGCCAATTAGAAGTATTGAACTCAACATACTTCAACGATGTGATAT
GTCATTTGCATCCAAGACTGATATCGAAGAATCATTCGAAGTTGGAGAATTTTCTGTTGAGTGTGTAGAAAATCATTCAG
GTAAAATGGTTGGAATCAAAAGAATTTCCAACAAACCTTACAAGACAGAATTTGAACTTGTTGATATAGAAAAAGTTGCC
AACAAAACAAAAATGATAGTTCCAAAATACACAGACAGCCATTTCCAAATCGACGACGAATTTATGGACTACATTCTTCC
TTTAATCGAAGGAGAAATCGAAGTAGAATACAAAAATGGAATAGCACAATACTTTGCATTCGACAAAGAAGATATTGTGA
AATTGTAA

Upstream 100 bases:

>100_bases
AAGGAGTGGTATTATCAAAAACTTATTAATAGCACAATCAGGTGGACCAACTTGTGCCATCAATGCAACATTGGCTGGTT
GTTACAAGAAAGCAATTGAA

Downstream 100 bases:

>100_bases
AATCAAGAGCAGAGTTCGTAATAATTCTGCTCTTTTTTAAAAATTTGTAAAAAACACTTTACAAAACAATATTATTGTGC
TATCATAGAAAGGTAGTCGT

Product: 6-phosphofructokinase

Products: NA

Alternate protein names: 6-phosphofructokinase, pyrophosphate dependent; PPi-dependent phosphofructokinase; PPi-PFK; Pyrophosphate-dependent 6-phosphofructose-1-kinase [H]

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MGFDNVYGALYGVQGLLDSKIIDLKSQIKTDKDLNRLKITPASALGSCRYKVDSEEKLAKIVEILKSFNINYFIYIGGND
SMDTVYQLSKYIEKIGEDINVMGSPKTIDNDLFGTDHTPGFGSAAKFVANSVYEIAKDVEIYDYRTITIVEIMGRYAGWL
TAAGAISKKLCNLGADLVYISEDTFEFDNLVKEINENFKRTDNILILVSEGIKDSSNNFISKTSGKKDKFGHAQLQGPSH
IIRDKLKEIYDMPIRSIELNILQRCDMSFASKTDIEESFEVGEFSVECVENHSGKMVGIKRISNKPYKTEFELVDIEKVA
NKTKMIVPKYTDSHFQIDDEFMDYILPLIEGEIEVEYKNGIAQYFAFDKEDIVKL

Sequences:

>Translated_375_residues
MGFDNVYGALYGVQGLLDSKIIDLKSQIKTDKDLNRLKITPASALGSCRYKVDSEEKLAKIVEILKSFNINYFIYIGGND
SMDTVYQLSKYIEKIGEDINVMGSPKTIDNDLFGTDHTPGFGSAAKFVANSVYEIAKDVEIYDYRTITIVEIMGRYAGWL
TAAGAISKKLCNLGADLVYISEDTFEFDNLVKEINENFKRTDNILILVSEGIKDSSNNFISKTSGKKDKFGHAQLQGPSH
IIRDKLKEIYDMPIRSIELNILQRCDMSFASKTDIEESFEVGEFSVECVENHSGKMVGIKRISNKPYKTEFELVDIEKVA
NKTKMIVPKYTDSHFQIDDEFMDYILPLIEGEIEVEYKNGIAQYFAFDKEDIVKL
>Mature_374_residues
GFDNVYGALYGVQGLLDSKIIDLKSQIKTDKDLNRLKITPASALGSCRYKVDSEEKLAKIVEILKSFNINYFIYIGGNDS
MDTVYQLSKYIEKIGEDINVMGSPKTIDNDLFGTDHTPGFGSAAKFVANSVYEIAKDVEIYDYRTITIVEIMGRYAGWLT
AAGAISKKLCNLGADLVYISEDTFEFDNLVKEINENFKRTDNILILVSEGIKDSSNNFISKTSGKKDKFGHAQLQGPSHI
IRDKLKEIYDMPIRSIELNILQRCDMSFASKTDIEESFEVGEFSVECVENHSGKMVGIKRISNKPYKTEFELVDIEKVAN
KTKMIVPKYTDSHFQIDDEFMDYILPLIEGEIEVEYKNGIAQYFAFDKEDIVKL

Specific function: Key control step of glycolysis. [C]

COG id: COG0205

COG function: function code G; 6-phosphofructokinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphofructokinase family [H]

Homologues:

Organism=Escherichia coli, GI1790350, Length=248, Percent_Identity=29.8387096774194, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: 3981 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 950 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012003
- InterPro:   IPR012829
- InterPro:   IPR022953
- InterPro:   IPR015912
- InterPro:   IPR000023 [H]

Pfam domain/function: PF00365 PFK [H]

EC number: =2.7.1.90 [H]

Molecular weight: Translated: 42441; Mature: 42310

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFDNVYGALYGVQGLLDSKIIDLKSQIKTDKDLNRLKITPASALGSCRYKVDSEEKLAK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHCCCEEECCCHHHHHH
IVEILKSFNINYFIYIGGNDSMDTVYQLSKYIEKIGEDINVMGSPKTIDNDLFGTDHTPG
HHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCCC
FGSAAKFVANSVYEIAKDVEIYDYRTITIVEIMGRYAGWLTAAGAISKKLCNLGADLVYI
CCHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
SEDTFEFDNLVKEINENFKRTDNILILVSEGIKDSSNNFISKTSGKKDKFGHAQLQGPSH
ECCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEECCCCCCCCCCCCCCCCHHH
IIRDKLKEIYDMPIRSIELNILQRCDMSFASKTDIEESFEVGEFSVECVENHSGKMVGIK
HHHHHHHHHHHCCCHHHHHHHHHHCCCCHHCCCCCHHHHCCCCEEEEEECCCCCCEEEEE
RISNKPYKTEFELVDIEKVANKTKMIVPKYTDSHFQIDDEFMDYILPLIEGEIEVEYKNG
ECCCCCCCCEEEEEEHHHHCCCCEEEEECCCCCCEEECHHHHHHHHHHHCCCEEEEECCC
IAQYFAFDKEDIVKL
HHHHHCCCHHHHHCC
>Mature Secondary Structure 
GFDNVYGALYGVQGLLDSKIIDLKSQIKTDKDLNRLKITPASALGSCRYKVDSEEKLAK
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHCCCEEECCCHHHHHH
IVEILKSFNINYFIYIGGNDSMDTVYQLSKYIEKIGEDINVMGSPKTIDNDLFGTDHTPG
HHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCCC
FGSAAKFVANSVYEIAKDVEIYDYRTITIVEIMGRYAGWLTAAGAISKKLCNLGADLVYI
CCHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
SEDTFEFDNLVKEINENFKRTDNILILVSEGIKDSSNNFISKTSGKKDKFGHAQLQGPSH
ECCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCEECCCCCCCCCCCCCCCCHHH
IIRDKLKEIYDMPIRSIELNILQRCDMSFASKTDIEESFEVGEFSVECVENHSGKMVGIK
HHHHHHHHHHHCCCHHHHHHHHHHCCCCHHCCCCCHHHHCCCCEEEEEECCCCCCEEEEE
RISNKPYKTEFELVDIEKVANKTKMIVPKYTDSHFQIDDEFMDYILPLIEGEIEVEYKNG
ECCCCCCCCEEEEEEHHHHCCCCEEEEECCCCCCEEECHHHHHHHHHHHCCCEEEEECCC
IAQYFAFDKEDIVKL
HHHHHCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10913106 [H]