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The map label for this gene is argF [H]

Identifier: 169824153

GI number: 169824153

Start: 512123

End: 513112

Strand: Direct

Name: argF [H]

Synonym: FMG_0456

Alternate gene names: 169824153

Gene position: 512123-513112 (Clockwise)

Preceding gene: 169824152

Following gene: 169824154

Centisome position: 28.49

GC content: 31.82

Gene sequence:

>990_bases
ATGTTAAAAGGAAGAGATTTTTTAACTTTAAAAGATTTCACTAAAGAAGAAATCGAACATTTACTAGATGTAAGTGCTGC
ATTAAAAGAAAAGAAAAGAATGGGTATTGTAGGAGAAACTTTAAAAGGCAAGAATATTGTTTTGTTATTTGAAAAAACTT
CTACTAGAACAAGATGTTCATTTGAAACAGCTTGTCACGATGAAGGTGGTAATGTAACATTCTTAGGTATGAATGATAGC
CAATTCGGTAAGAAAGAATCTGTAAGAGACTCTGCTTTAGTATTATCAAGATTCTACGATGGTATCGAATTTAGAGGATT
TGACCATGCAACTGTAGAAGAATTAGCAAAATATTCTTCAGTTCCAGTATGGAATGGTTTAACTGATATTTATCACCCAA
CACAAATCTTAGCAGACTTTTTAACTGTAAAAGAAAACATCCACAAAAACTTAGACCAAGTTAAATTCGTTTATGTTGGT
GATGGTAGAAACAACATGGCAAACTCTTTAATGATAGGAGCTGCTAAATTAGGTATGGAATTTGTAAATCTTGCTCCAAA
AGAATTACATCCATCAAATGAAATGATGAACACTATCCAAGAAATAGCTAAAGAATCTGGTGCAAAAATCACAGTAACTG
ATGATTTCAATAGCTTAAAAGGTGCAGATGTAATCTACACTGACGTTTGGGTATCAATGGGTGAAGAAGATCAATTCGAA
GAAAGAATCAATCTTCTTAAAGATTACCAAGTAGATATGAAGAAAATCGAAATGACTGAAAATCCTAACGTAATCTTCTT
ACATTGCTTACCATCTTTCCACAACTTAGAAACTAAAGTTGGTCGTGAAATCCACGAAAAATTTGGCTTGAGTGAAATGG
AAGTAACTGATGAAGTATTCTACAGCAAATATTCAAAAGTATTTGATGAAGCTGAAAATAGAATGCACACTATCAAAGCA
GTTATCGTTGAAACAATTGGTAATAAATAA

Upstream 100 bases:

>100_bases
AAGCTGATGTAAATATAAGAACTATTAAATCAGGCGAATTATCTAGAGGACGTGGGGGTCCAAGATGTATGAGTATGCCA
TTTGAAAGGGAGATGTAATT

Downstream 100 bases:

>100_bases
ATTTTAATTTTTAAGAGGTAACTTTCACGAGTTATCTCTTTTTTTACTGGAAAAATATTGCAATTTTCATGAATTTTTGG
TAAAATATCTTGTCATTGTC

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MLKGRDFLTLKDFTKEEIEHLLDVSAALKEKKRMGIVGETLKGKNIVLLFEKTSTRTRCSFETACHDEGGNVTFLGMNDS
QFGKKESVRDSALVLSRFYDGIEFRGFDHATVEELAKYSSVPVWNGLTDIYHPTQILADFLTVKENIHKNLDQVKFVYVG
DGRNNMANSLMIGAAKLGMEFVNLAPKELHPSNEMMNTIQEIAKESGAKITVTDDFNSLKGADVIYTDVWVSMGEEDQFE
ERINLLKDYQVDMKKIEMTENPNVIFLHCLPSFHNLETKVGREIHEKFGLSEMEVTDEVFYSKYSKVFDEAENRMHTIKA
VIVETIGNK

Sequences:

>Translated_329_residues
MLKGRDFLTLKDFTKEEIEHLLDVSAALKEKKRMGIVGETLKGKNIVLLFEKTSTRTRCSFETACHDEGGNVTFLGMNDS
QFGKKESVRDSALVLSRFYDGIEFRGFDHATVEELAKYSSVPVWNGLTDIYHPTQILADFLTVKENIHKNLDQVKFVYVG
DGRNNMANSLMIGAAKLGMEFVNLAPKELHPSNEMMNTIQEIAKESGAKITVTDDFNSLKGADVIYTDVWVSMGEEDQFE
ERINLLKDYQVDMKKIEMTENPNVIFLHCLPSFHNLETKVGREIHEKFGLSEMEVTDEVFYSKYSKVFDEAENRMHTIKA
VIVETIGNK
>Mature_329_residues
MLKGRDFLTLKDFTKEEIEHLLDVSAALKEKKRMGIVGETLKGKNIVLLFEKTSTRTRCSFETACHDEGGNVTFLGMNDS
QFGKKESVRDSALVLSRFYDGIEFRGFDHATVEELAKYSSVPVWNGLTDIYHPTQILADFLTVKENIHKNLDQVKFVYVG
DGRNNMANSLMIGAAKLGMEFVNLAPKELHPSNEMMNTIQEIAKESGAKITVTDDFNSLKGADVIYTDVWVSMGEEDQFE
ERINLLKDYQVDMKKIEMTENPNVIFLHCLPSFHNLETKVGREIHEKFGLSEMEVTDEVFYSKYSKVFDEAENRMHTIKA
VIVETIGNK

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=327, Percent_Identity=41.2844036697248, Blast_Score=235, Evalue=4e-62,
Organism=Homo sapiens, GI18105007, Length=341, Percent_Identity=25.2199413489736, Blast_Score=84, Evalue=1e-16,
Organism=Escherichia coli, GI1790703, Length=326, Percent_Identity=52.1472392638037, Blast_Score=348, Evalue=2e-97,
Organism=Escherichia coli, GI1786469, Length=327, Percent_Identity=51.6819571865443, Blast_Score=343, Evalue=8e-96,
Organism=Escherichia coli, GI48994908, Length=375, Percent_Identity=26.1333333333333, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI2367364, Length=306, Percent_Identity=28.4313725490196, Blast_Score=77, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322373, Length=342, Percent_Identity=32.4561403508772, Blast_Score=160, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6322331, Length=289, Percent_Identity=26.643598615917, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24642586, Length=341, Percent_Identity=24.633431085044, Blast_Score=78, Evalue=8e-15,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2066 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 37433; Mature: 37433

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKGRDFLTLKDFTKEEIEHLLDVSAALKEKKRMGIVGETLKGKNIVLLFEKTSTRTRCS
CCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCEEC
FETACHDEGGNVTFLGMNDSQFGKKESVRDSALVLSRFYDGIEFRGFDHATVEELAKYSS
CHHHCCCCCCCEEEEECCCHHCCCHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHCC
VPVWNGLTDIYHPTQILADFLTVKENIHKNLDQVKFVYVGDGRNNMANSLMIGAAKLGME
CCCCCCCHHHCCHHHHHHHHHHHHHHHHCCHHHEEEEEEECCCCCHHHHHHHHHHHHHHH
FVNLAPKELHPSNEMMNTIQEIAKESGAKITVTDDFNSLKGADVIYTDVWVSMGEEDQFE
HHHCCCHHCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEEHHHHCCCCHHHH
ERINLLKDYQVDMKKIEMTENPNVIFLHCLPSFHNLETKVGREIHEKFGLSEMEVTDEVF
HHHHHHHHHHHHHHHEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHH
YSKYSKVFDEAENRMHTIKAVIVETIGNK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLKGRDFLTLKDFTKEEIEHLLDVSAALKEKKRMGIVGETLKGKNIVLLFEKTSTRTRCS
CCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCEEC
FETACHDEGGNVTFLGMNDSQFGKKESVRDSALVLSRFYDGIEFRGFDHATVEELAKYSS
CHHHCCCCCCCEEEEECCCHHCCCHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHCC
VPVWNGLTDIYHPTQILADFLTVKENIHKNLDQVKFVYVGDGRNNMANSLMIGAAKLGME
CCCCCCCHHHCCHHHHHHHHHHHHHHHHCCHHHEEEEEEECCCCCHHHHHHHHHHHHHHH
FVNLAPKELHPSNEMMNTIQEIAKESGAKITVTDDFNSLKGADVIYTDVWVSMGEEDQFE
HHHCCCHHCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEEHHHHCCCCHHHH
ERINLLKDYQVDMKKIEMTENPNVIFLHCLPSFHNLETKVGREIHEKFGLSEMEVTDEVF
HHHHHHHHHHHHHHHEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHH
YSKYSKVFDEAENRMHTIKAVIVETIGNK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA