Click here to switch to the map view.

The map label for this gene is ykuT [H]

Identifier: 169824147

GI number: 169824147

Start: 507567

End: 508406

Strand: Direct

Name: ykuT [H]

Synonym: FMG_0450

Alternate gene names: 169824147

Gene position: 507567-508406 (Clockwise)

Preceding gene: 169824146

Following gene: 169824148

Centisome position: 28.24

GC content: 30.83

Gene sequence:

>840_bases
ATGTTATTTAGTATTCAAAAATTTAACGAAATATTTTATAATTCAGCCGGCCAACTAAATTTGTTGGCCAAGATTTTATT
GTCCTTGTTAATTATTGCGCTTACGCAAGTTGTCGTAAGCATTTTAACTACGAGCTTCGATAAATTATTAATGAAAAAAG
GAAGTTCCATCGAAGGAAGACAAATCACGGTTACCAAATTGTTGAACAATACAATAAAATATTTGATTTATTTTTTCTGT
GTAGTTCATGTCCTAGATTTATTCGGGGTTAAAACAGATAAAATATTGGCAACTGCTGGTATCGGTGGGGTTGCAATTGG
TTTTGGTGCGCAATTTATAATCAGGGATGTAATCAGTGGGCTTGCAATAATTCTTGAAAATCAATTCAAAGTGACAGATC
ATGTCATTATCAATGGAATTGAAGGAAATGTTCAAGAATTGGGACTTCGCGTTACAAAAATCAGAGGATTTGACGGAGCT
ATTCATTTGATTAGTAACGGTCAAATCAACACAGTGACTAATTTATCTAAAGAAAATCAAAGAATTGAAGTTAAAATGGA
AGTTCCAATTAAATATAGTTTGGATCAATACGCAGAAATTGTAAATGAAATTTCCAATGAATTGGTAGACAAGTATTCAG
ATATTGTAAAAAAACCAGAATTAATTGGAGTTACCAAAATGGACAAGAACTCCATGACTATTACGATTTGGGGAAGTTGC
AAACCAGAATCACAATATTTGTATCAAAGAGAAATTATTAAAAAATTCATAGAAAAAGCCAAATCAAAATCAATGGATTT
GAATTGTTATTTTGTAGCAGGTGATGAAAATGAAATATAA

Upstream 100 bases:

>100_bases
TGAAATGATAGCATTGAAAAAAGAACTTCCAATCTCAAAGATTTGGTCGTATCTTAAAGTAGATGGAGTAATTTTTGTGA
ATGAGGTAAAAGAATAATTA

Downstream 100 bases:

>100_bases
AGTAAATGATATTGTAACACTAAAAAAAGGTCATCCATGTGGCGAAAATAAATGGGAGATTTTGAGAACTGGAGCAGATA
TTAAATTAAAATGCTTGGGA

Product: mechanosensitive ion channel family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MLFSIQKFNEIFYNSAGQLNLLAKILLSLLIIALTQVVVSILTTSFDKLLMKKGSSIEGRQITVTKLLNNTIKYLIYFFC
VVHVLDLFGVKTDKILATAGIGGVAIGFGAQFIIRDVISGLAIILENQFKVTDHVIINGIEGNVQELGLRVTKIRGFDGA
IHLISNGQINTVTNLSKENQRIEVKMEVPIKYSLDQYAEIVNEISNELVDKYSDIVKKPELIGVTKMDKNSMTITIWGSC
KPESQYLYQREIIKKFIEKAKSKSMDLNCYFVAGDENEI

Sequences:

>Translated_279_residues
MLFSIQKFNEIFYNSAGQLNLLAKILLSLLIIALTQVVVSILTTSFDKLLMKKGSSIEGRQITVTKLLNNTIKYLIYFFC
VVHVLDLFGVKTDKILATAGIGGVAIGFGAQFIIRDVISGLAIILENQFKVTDHVIINGIEGNVQELGLRVTKIRGFDGA
IHLISNGQINTVTNLSKENQRIEVKMEVPIKYSLDQYAEIVNEISNELVDKYSDIVKKPELIGVTKMDKNSMTITIWGSC
KPESQYLYQREIIKKFIEKAKSKSMDLNCYFVAGDENEI
>Mature_279_residues
MLFSIQKFNEIFYNSAGQLNLLAKILLSLLIIALTQVVVSILTTSFDKLLMKKGSSIEGRQITVTKLLNNTIKYLIYFFC
VVHVLDLFGVKTDKILATAGIGGVAIGFGAQFIIRDVISGLAIILENQFKVTDHVIINGIEGNVQELGLRVTKIRGFDGA
IHLISNGQINTVTNLSKENQRIEVKMEVPIKYSLDQYAEIVNEISNELVDKYSDIVKKPELIGVTKMDKNSMTITIWGSC
KPESQYLYQREIIKKFIEKAKSKSMDLNCYFVAGDENEI

Specific function: May play a role in resistance to osmotic downshock [H]

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI1789291, Length=273, Percent_Identity=23.8095238095238, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787591, Length=251, Percent_Identity=24.3027888446215, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87081787, Length=250, Percent_Identity=25.6, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 31251; Mature: 31251

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFSIQKFNEIFYNSAGQLNLLAKILLSLLIIALTQVVVSILTTSFDKLLMKKGSSIEGR
CCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
QITVTKLLNNTIKYLIYFFCVVHVLDLFGVKTDKILATAGIGGVAIGFGAQFIIRDVISG
EEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHH
LAIILENQFKVTDHVIINGIEGNVQELGLRVTKIRGFDGAIHLISNGQINTVTNLSKENQ
HHHHHCCCCEEECEEEEECCCCCHHHHCEEEEEEECCCCEEEEEECCCEEEHCCCCCCCC
RIEVKMEVPIKYSLDQYAEIVNEISNELVDKYSDIVKKPELIGVTKMDKNSMTITIWGSC
EEEEEEECCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEECC
KPESQYLYQREIIKKFIEKAKSKSMDLNCYFVAGDENEI
CCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCC
>Mature Secondary Structure
MLFSIQKFNEIFYNSAGQLNLLAKILLSLLIIALTQVVVSILTTSFDKLLMKKGSSIEGR
CCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
QITVTKLLNNTIKYLIYFFCVVHVLDLFGVKTDKILATAGIGGVAIGFGAQFIIRDVISG
EEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHH
LAIILENQFKVTDHVIINGIEGNVQELGLRVTKIRGFDGAIHLISNGQINTVTNLSKENQ
HHHHHCCCCEEECEEEEECCCCCHHHHCEEEEEEECCCCEEEEEECCCEEEHCCCCCCCC
RIEVKMEVPIKYSLDQYAEIVNEISNELVDKYSDIVKKPELIGVTKMDKNSMTITIWGSC
EEEEEEECCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEEEECC
KPESQYLYQREIIKKFIEKAKSKSMDLNCYFVAGDENEI
CCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]