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The map label for this gene is ppx [C]

Identifier: 169824137

GI number: 169824137

Start: 497120

End: 498019

Strand: Direct

Name: ppx [C]

Synonym: FMG_0440

Alternate gene names: 169824137

Gene position: 497120-498019 (Clockwise)

Preceding gene: 169824135

Following gene: 169824138

Centisome position: 27.66

GC content: 31.56

Gene sequence:

>900_bases
ATGATTTATGCAGTCATTGATATAGGATCAAATACAATTAGATTATCGGTTTATAAAGTTATAGGAGATGAAGTTAAGAA
TCTTTTTAACGAAAAATCAAGTGCTTCACTGGCATCATTCATAGAAAAAGGGATGATGAACGAACATGGGATTCAAAAGT
TGATTAATACACTAAAAGAATTTAAGAATTTGATTTCAAATTTTGAAGATATTTCAAAAACATATGCAATCGCTACTGCA
TCCATTAGAAATTCTTGTAATAGACGAGAAATCATTGAAAGAGTTCGAACAGAAGTAGGAATAGACATTGAACTTATTAG
CGGAGAAGAGGAAGCAAAGTTATCTTTTTTAGGATCTGGAATCGATTCTCAAAGCGGTATATTGACTGATATTGGTGGTG
GAAGCAGTGAGATTGTAGTATTTGAGCAGGGAAAAGTTGTGAAGACTTCTAGTTTGAATATAGGTTCACTAGTTGCTTTT
GATAATTTTGCAAGAGGATTATTCATTACTAAAGATGAGAAAAAATTATTGGAAGATGATATAAAGTTGATGCTTGCTTC
TAATAATCTCAACAGAGTTCAACACGATCTTGTGTGTGCTGTTGGTGGAAGTGCGAGAGCATGCCTTAAACTTTACAATG
AATATTATGACAAGGAAGCTGGTAATGTAATTATTACTATGGATGGTTTGAAAAATCTCATTAATACTCTTATAAATATG
GAAAACAGAGCAAAGATGAAATTGATTTTGAAAGTTAAGGCTGATAGAATTCACACATTGATTCCAGGAATGATAATTTT
GTATAGAATTGCAAAATATTTCTACGCAGACATTATAAGAGTTAGTATGACTGGTATTAGAGAAGGATTCGTTTACAGTA
AGATATTAGAAAGGGGATAA

Upstream 100 bases:

>100_bases
ACATTTTTTGTAAAAATAATGTAAATTAAACGAAAAATTATTGTAAATTTGACAATTTAACTGATAAAATATAGTAAAAT
TAAACTAAAGAGGTGTTTTT

Downstream 100 bases:

>100_bases
AATGAACGATATTTCATTCACCCAAAATAGGGAATTATCATGGTTAAAATTTAATGAAAGAGTGCTTGAGGAAGCAGCAG
ATAAAAGTGTAGAATTATTT

Product: exopolyphosphatase

Products: (polyphosphate)n-1; phosphate

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MIYAVIDIGSNTIRLSVYKVIGDEVKNLFNEKSSASLASFIEKGMMNEHGIQKLINTLKEFKNLISNFEDISKTYAIATA
SIRNSCNRREIIERVRTEVGIDIELISGEEEAKLSFLGSGIDSQSGILTDIGGGSSEIVVFEQGKVVKTSSLNIGSLVAF
DNFARGLFITKDEKKLLEDDIKLMLASNNLNRVQHDLVCAVGGSARACLKLYNEYYDKEAGNVIITMDGLKNLINTLINM
ENRAKMKLILKVKADRIHTLIPGMIILYRIAKYFYADIIRVSMTGIREGFVYSKILERG

Sequences:

>Translated_299_residues
MIYAVIDIGSNTIRLSVYKVIGDEVKNLFNEKSSASLASFIEKGMMNEHGIQKLINTLKEFKNLISNFEDISKTYAIATA
SIRNSCNRREIIERVRTEVGIDIELISGEEEAKLSFLGSGIDSQSGILTDIGGGSSEIVVFEQGKVVKTSSLNIGSLVAF
DNFARGLFITKDEKKLLEDDIKLMLASNNLNRVQHDLVCAVGGSARACLKLYNEYYDKEAGNVIITMDGLKNLINTLINM
ENRAKMKLILKVKADRIHTLIPGMIILYRIAKYFYADIIRVSMTGIREGFVYSKILERG
>Mature_299_residues
MIYAVIDIGSNTIRLSVYKVIGDEVKNLFNEKSSASLASFIEKGMMNEHGIQKLINTLKEFKNLISNFEDISKTYAIATA
SIRNSCNRREIIERVRTEVGIDIELISGEEEAKLSFLGSGIDSQSGILTDIGGGSSEIVVFEQGKVVKTSSLNIGSLVAF
DNFARGLFITKDEKKLLEDDIKLMLASNNLNRVQHDLVCAVGGSARACLKLYNEYYDKEAGNVIITMDGLKNLINTLINM
ENRAKMKLILKVKADRIHTLIPGMIILYRIAKYFYADIIRVSMTGIREGFVYSKILERG

Specific function: Degradation Of Inorganic Polyphosphates. Orthophosphate Is Released Progressively From The Ends Of Polyphosphate Of Circa 500 Residues Long, While Chains Of Circa 15 Residues Compete Poorly With Polyphosphate As Substrate. [C]

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI1788848, Length=296, Percent_Identity=23.9864864864865, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI48994966, Length=169, Percent_Identity=27.2189349112426, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003695 [H]

Pfam domain/function: PF02541 Ppx-GppA [H]

EC number: 3.6.1.11

Molecular weight: Translated: 33309; Mature: 33309

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYAVIDIGSNTIRLSVYKVIGDEVKNLFNEKSSASLASFIEKGMMNEHGIQKLINTLKE
CEEEEEEECCCEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHH
FKNLISNFEDISKTYAIATASIRNSCNRREIIERVRTEVGIDIELISGEEEAKLSFLGSG
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCEEEEECCCCHHHHHHHCCC
IDSQSGILTDIGGGSSEIVVFEQGKVVKTSSLNIGSLVAFDNFARGLFITKDEKKLLEDD
CCCCCCEEEECCCCCCEEEEEECCCEEEECCCCCCHHHHHHHHHCCEEEECHHHHHHHHH
IKLMLASNNLNRVQHDLVCAVGGSARACLKLYNEYYDKEAGNVIITMDGLKNLINTLINM
HEEEEECCCHHHHHHHHEEEECCCHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHCC
ENRAKMKLILKVKADRIHTLIPGMIILYRIAKYFYADIIRVSMTGIREGFVYSKILERG
CCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIYAVIDIGSNTIRLSVYKVIGDEVKNLFNEKSSASLASFIEKGMMNEHGIQKLINTLKE
CEEEEEEECCCEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHH
FKNLISNFEDISKTYAIATASIRNSCNRREIIERVRTEVGIDIELISGEEEAKLSFLGSG
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCEEEEECCCCHHHHHHHCCC
IDSQSGILTDIGGGSSEIVVFEQGKVVKTSSLNIGSLVAFDNFARGLFITKDEKKLLEDD
CCCCCCEEEECCCCCCEEEEEECCCEEEECCCCCCHHHHHHHHHCCEEEECHHHHHHHHH
IKLMLASNNLNRVQHDLVCAVGGSARACLKLYNEYYDKEAGNVIITMDGLKNLINTLINM
HEEEEECCCHHHHHHHHEEEECCCHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHCC
ENRAKMKLILKVKADRIHTLIPGMIILYRIAKYFYADIIRVSMTGIREGFVYSKILERG
CCCCEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (polyphosphate)n; H2O

Specific reaction: (polyphosphate)n + H2O = (polyphosphate)n-1 + phosphate

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]