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The map label for this gene is obg

Identifier: 169824064

GI number: 169824064

Start: 419518

End: 420783

Strand: Direct

Name: obg

Synonym: FMG_0367

Alternate gene names: 169824064

Gene position: 419518-420783 (Clockwise)

Preceding gene: 169824063

Following gene: 169824065

Centisome position: 23.34

GC content: 34.91

Gene sequence:

>1266_bases
ATGTTTATAGATGTAGCAAAGATAGAACTTAAAGCTGGAAAAGGTGGAGACGGTTCTGTTGCATTTAGAAGAGAAAAATA
CGAACCATCAGGTGGTCCTGCAGGTGGCGACGGCGGAGATGGCGGTAGTATTATAATTGTCGGAGACAAAGACATTAAAA
CTTTGATGGATTACAGTTATCGATCCATTTACAAAGCTGAAAGTGGCGGCGACGGCAGAAATAAAAAACAATTTGGTAAA
AAAGGTGAAGATTTAATTCTTAAAGTTCCAGTTGGGACTTTGGTTAAAGATTACGATACAGATACGGTTATCTACGATGT
AAAACACGATAAGGAAGAGTTTGTAATTTGCAAAGGTGGCAAAGGCGGAAAGGGAAATGTTCATTTCAAATCATCTATAA
GACAAGCACCAAGATTTGCAGAGCCTGGAGAAAAAGGCGAAGAAAAAACAATTAAGTTAGAATTGAAACTTCTAGCTGAT
GTTGGATTAATTGGTCTTCCTAACGTTGGGAAATCTACACTGTTGTCTATAATGTCAAACGCAAGACCTAAAATTGCAAA
TTATCATTTTACAACACTTGAGCCAAATCTTGGAGTGTGCAAAGTTGGAGAAAAAAGTTTCGTACTTGCAGATATTCCTG
GGTTAATTGAAGGAGCAAGTGAAGGGCTGGGACTTGGTCATGATTTCTTGAAACACATTGAAAGAACTAAAATTTTAGTT
CACGTGTTGGATATTTCAGGAAGTGAAGGTAGAAATCCAATCGAAGATTTTGAACTTATCAATAGTGAATTGTCTTCATA
CAATATCAAATTGAATGATAAAAAAATGCTTGTGGTTTTGAATAAAACAGACCTAGGAGCAGAAGATAATATAAAAGAAT
TTAGGGAAAAATATTCTGACAAAGTTGATGAAATCGTAGAGATAAGTGCTGCTACAACTGAAAATGTAGACAAGCTTATG
TATTTGATTGCAGATACTTTGGACAGTATAGAAGATGATTATTCTACATTGGATGAACAATACGTTTACTTTGAAGAAGA
AAAAGAGCCTGATTTCAAAGTTAGAAGAGAAAACGAAAACTACATCGTAGAAGGTCCGTTGATTGAAAACTTAATTTACA
GAACAAACTTTGAAGTGTATGAATCTGTTAATCACTTGCAAAAAGTTCTTGAAGACAAGGGAGTTATCCAACAATTAAAA
GATCTTGGAATTCAAGATGGAGACAACGTAGTTATCGGTGATGTAGAATTTGATTTTTACGAATAG

Upstream 100 bases:

>100_bases
TATAAATCGGATTTCCTTTTTATAATCGTAAGGTGTTGCTTTTTTAGTGGAAAATAATGTAAACTTACAAGTATAGTGGG
CATTAATAAAGAGGTGAAAA

Downstream 100 bases:

>100_bases
GAGATAAAATGATAACACCAAAACAAAGAGCAAAATTAAAAAAGATTTCTCATGGTTACAAACCACTTGTAAACATCGGT
AAAGGTGGAATTTCAGAAAA

Product: putative GTP-binding protein

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MFIDVAKIELKAGKGGDGSVAFRREKYEPSGGPAGGDGGDGGSIIIVGDKDIKTLMDYSYRSIYKAESGGDGRNKKQFGK
KGEDLILKVPVGTLVKDYDTDTVIYDVKHDKEEFVICKGGKGGKGNVHFKSSIRQAPRFAEPGEKGEEKTIKLELKLLAD
VGLIGLPNVGKSTLLSIMSNARPKIANYHFTTLEPNLGVCKVGEKSFVLADIPGLIEGASEGLGLGHDFLKHIERTKILV
HVLDISGSEGRNPIEDFELINSELSSYNIKLNDKKMLVVLNKTDLGAEDNIKEFREKYSDKVDEIVEISAATTENVDKLM
YLIADTLDSIEDDYSTLDEQYVYFEEEKEPDFKVRRENENYIVEGPLIENLIYRTNFEVYESVNHLQKVLEDKGVIQQLK
DLGIQDGDNVVIGDVEFDFYE

Sequences:

>Translated_421_residues
MFIDVAKIELKAGKGGDGSVAFRREKYEPSGGPAGGDGGDGGSIIIVGDKDIKTLMDYSYRSIYKAESGGDGRNKKQFGK
KGEDLILKVPVGTLVKDYDTDTVIYDVKHDKEEFVICKGGKGGKGNVHFKSSIRQAPRFAEPGEKGEEKTIKLELKLLAD
VGLIGLPNVGKSTLLSIMSNARPKIANYHFTTLEPNLGVCKVGEKSFVLADIPGLIEGASEGLGLGHDFLKHIERTKILV
HVLDISGSEGRNPIEDFELINSELSSYNIKLNDKKMLVVLNKTDLGAEDNIKEFREKYSDKVDEIVEISAATTENVDKLM
YLIADTLDSIEDDYSTLDEQYVYFEEEKEPDFKVRRENENYIVEGPLIENLIYRTNFEVYESVNHLQKVLEDKGVIQQLK
DLGIQDGDNVVIGDVEFDFYE
>Mature_421_residues
MFIDVAKIELKAGKGGDGSVAFRREKYEPSGGPAGGDGGDGGSIIIVGDKDIKTLMDYSYRSIYKAESGGDGRNKKQFGK
KGEDLILKVPVGTLVKDYDTDTVIYDVKHDKEEFVICKGGKGGKGNVHFKSSIRQAPRFAEPGEKGEEKTIKLELKLLAD
VGLIGLPNVGKSTLLSIMSNARPKIANYHFTTLEPNLGVCKVGEKSFVLADIPGLIEGASEGLGLGHDFLKHIERTKILV
HVLDISGSEGRNPIEDFELINSELSSYNIKLNDKKMLVVLNKTDLGAEDNIKEFREKYSDKVDEIVEISAATTENVDKLM
YLIADTLDSIEDDYSTLDEQYVYFEEEKEPDFKVRRENENYIVEGPLIENLIYRTNFEVYESVNHLQKVLEDKGVIQQLK
DLGIQDGDNVVIGDVEFDFYE

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=321, Percent_Identity=39.8753894080997, Blast_Score=188, Evalue=7e-48,
Organism=Homo sapiens, GI111955139, Length=303, Percent_Identity=36.6336633663366, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI111955063, Length=189, Percent_Identity=39.6825396825397, Blast_Score=118, Evalue=8e-27,
Organism=Homo sapiens, GI58761500, Length=141, Percent_Identity=33.3333333333333, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI4557537, Length=117, Percent_Identity=37.6068376068376, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI4758796, Length=128, Percent_Identity=35.15625, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1789574, Length=355, Percent_Identity=44.5070422535211, Blast_Score=245, Evalue=3e-66,
Organism=Escherichia coli, GI1787454, Length=158, Percent_Identity=33.5443037974684, Blast_Score=82, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17508313, Length=289, Percent_Identity=39.4463667820069, Blast_Score=154, Evalue=9e-38,
Organism=Caenorhabditis elegans, GI17552324, Length=378, Percent_Identity=31.2169312169312, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17509631, Length=137, Percent_Identity=32.8467153284672, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71981008, Length=116, Percent_Identity=37.0689655172414, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17555344, Length=116, Percent_Identity=34.4827586206897, Blast_Score=72, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6321962, Length=165, Percent_Identity=46.6666666666667, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6321612, Length=128, Percent_Identity=35.15625, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6321649, Length=141, Percent_Identity=30.4964539007092, Blast_Score=71, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6319281, Length=129, Percent_Identity=32.5581395348837, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI20129375, Length=334, Percent_Identity=37.125748502994, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24585318, Length=367, Percent_Identity=32.6975476839237, Blast_Score=162, Evalue=4e-40,
Organism=Drosophila melanogaster, GI24640873, Length=128, Percent_Identity=32.8125, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24640877, Length=128, Percent_Identity=32.8125, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24640875, Length=128, Percent_Identity=32.8125, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21356473, Length=117, Percent_Identity=38.4615384615385, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17981711, Length=128, Percent_Identity=35.15625, Blast_Score=72, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_FINM2 (B0S3Z4)

Other databases:

- EMBL:   AP008971
- RefSeq:   YP_001691675.1
- ProteinModelPortal:   B0S3Z4
- SMR:   B0S3Z4
- GeneID:   6019274
- GenomeReviews:   AP008971_GR
- KEGG:   fma:FMG_0367
- HOGENOM:   HBG716038
- OMA:   HFTTLVP
- ProtClustDB:   PRK12297
- BioCyc:   FMAG334413:FMG_0367-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR015349
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR03595
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF09269 DUF1967; PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF102741 GTP-bd_prot_GTP1/OBG_C; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 46781; Mature: 46781

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIDVAKIELKAGKGGDGSVAFRREKYEPSGGPAGGDGGDGGSIIIVGDKDIKTLMDYSY
CEEEEEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHH
RSIYKAESGGDGRNKKQFGKKGEDLILKVPVGTLVKDYDTDTVIYDVKHDKEEFVICKGG
HHHEECCCCCCCCCHHHHCCCCCCEEEECCHHHHHHCCCCCEEEEEEECCCCEEEEEECC
KGGKGNVHFKSSIRQAPRFAEPGEKGEEKTIKLELKLLADVGLIGLPNVGKSTLLSIMSN
CCCCCCEEEHHHHHCCCCCCCCCCCCCCCEEEEEEEEEECCCEEECCCCCHHHHHHHHHC
ARPKIANYHFTTLEPNLGVCKVGEKSFVLADIPGLIEGASEGLGLGHDFLKHIERTKILV
CCCCCCCEEEEEECCCCCEEEECCCCEEEECCCHHHHCCCCCCCCCHHHHHHHHHHEEEE
HVLDISGSEGRNPIEDFELINSELSSYNIKLNDKKMLVVLNKTDLGAEDNIKEFREKYSD
EEEECCCCCCCCCHHHHHHHHHHHHHEEEEECCCEEEEEEECCCCCCCCCHHHHHHHHHH
KVDEIVEISAATTENVDKLMYLIADTLDSIEDDYSTLDEQYVYFEEEKEPDFKVRRENEN
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCEEEECCCC
YIVEGPLIENLIYRTNFEVYESVNHLQKVLEDKGVIQQLKDLGIQDGDNVVIGDVEFDFY
EEEECHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCC
E
C
>Mature Secondary Structure
MFIDVAKIELKAGKGGDGSVAFRREKYEPSGGPAGGDGGDGGSIIIVGDKDIKTLMDYSY
CEEEEEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHH
RSIYKAESGGDGRNKKQFGKKGEDLILKVPVGTLVKDYDTDTVIYDVKHDKEEFVICKGG
HHHEECCCCCCCCCHHHHCCCCCCEEEECCHHHHHHCCCCCEEEEEEECCCCEEEEEECC
KGGKGNVHFKSSIRQAPRFAEPGEKGEEKTIKLELKLLADVGLIGLPNVGKSTLLSIMSN
CCCCCCEEEHHHHHCCCCCCCCCCCCCCCEEEEEEEEEECCCEEECCCCCHHHHHHHHHC
ARPKIANYHFTTLEPNLGVCKVGEKSFVLADIPGLIEGASEGLGLGHDFLKHIERTKILV
CCCCCCCEEEEEECCCCCEEEECCCCEEEECCCHHHHCCCCCCCCCHHHHHHHHHHEEEE
HVLDISGSEGRNPIEDFELINSELSSYNIKLNDKKMLVVLNKTDLGAEDNIKEFREKYSD
EEEECCCCCCCCCHHHHHHHHHHHHHEEEEECCCEEEEEEECCCCCCCCCHHHHHHHHHH
KVDEIVEISAATTENVDKLMYLIADTLDSIEDDYSTLDEQYVYFEEEKEPDFKVRRENEN
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCEEEECCCC
YIVEGPLIENLIYRTNFEVYESVNHLQKVLEDKGVIQQLKDLGIQDGDNVVIGDVEFDFY
EEEECHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCC
E
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA