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The map label for this gene is clpB [H]

Identifier: 169824032

GI number: 169824032

Start: 388362

End: 390782

Strand: Direct

Name: clpB [H]

Synonym: FMG_0335

Alternate gene names: 169824032

Gene position: 388362-390782 (Clockwise)

Preceding gene: 169824031

Following gene: 169824033

Centisome position: 21.6

GC content: 36.93

Gene sequence:

>2421_bases
TTGAGAAAATCAGATATTTATAATTTGAGAACAGAAGCTGTGTATGAGGCGATTAGTTTGAAGCATGCTGATCTTGGAGT
GGAGCATGTTTTACTTGCGATGTTCAAGTTTGACTTCAAGGCGTCTCAATATTTGAAAAAACACGGTGGAAATTACGAAA
AAATTAGAAATTTAATTATAGATGAGTTGGGTTATGGAGATAGCGATGAGACTAACCAAAGAATTAGCCCGAAACTTGAG
GAGATAATCACTCAAGCTGTACAATTGTCCAACACTTATGGCGAAAGGACGATTACTCCGGAACATATTATGGCAGCTTT
ATGCTTGGATAGTTCGAACTACGCTAATCATTTGATGAAGAGAACAGGCGTGGATATTATGAAATTGACAGCGGAACTTC
GTAAATATTTCTTCATGAAGATGAAGAGAGAACGAGGAGATGTCAACGACAATTCAGCTAATTCTTCCAAGCCAAATGAG
ATTGAAAAGTACACTAAGAATTTGAATGAAATGGCGAAAGAAGGAAAGATTGATCCATGTATCGGTCGTGAGGAAGAAAT
CGAAAGAATTATTCAAGTACTTCTTAGACGTAAGAAAAATAATCCTGTGTTGATTGGAAATCCTGGTGTCGGAAAGACTG
CTATCGTGGAAGGCTTAGCTGTCAAGATTGTCAAGGGAGATGTGAATGATATTTTCAAGGACAAGGAGATTTTGTCATTG
GATTTGGCGGCGTTGTTGGCAGGGACAAAATACAGAGGAGATTTTGAAGAAAGAATTAAAAAAGTTATCGATACTTTGTC
AAATTCCGAAAACAAAATTTTATTTATAGATGAACTTCATTCGTTGATGGGCGCAGGTGGTGCAGAGGGTGCGCTGGATG
CATCAAATATTTTGAAACCATCATTGGCGAGAGGCGATTTGCAAATAATCGGAGCTACAACTATCAATGAATACAGAAAA
ACTATCGAAAAGGACCAAGCTTTTGAAAGAAGACTTCAAACTATTATGGTAGATGAGCCTTCTGTTTCGGATTCTATTCA
AGTTATTGAAGGATTGAAGGACAAATACGAATCACATCACCACGTTCTAATCAGTGATGAAGCAATCAAAGCGAGTGTTG
AATTATCGCACAGATATTTGAATGATAGATATTTGCCAGATAAGGCGATAGATTTGATAGATGAAGCTCAATCGATGGTT
AGAGTAAAAAACTTCACTGGTGGCAAAAATTATGCGAAAATTCTAGAAGAATTAGAAGAAGAAAAGCAAGAAGCTATTCA
AAATTCCGACTTTTTGCTTGCAGCAGAAAAAAGAGATGCCATCAAGGAAGTAGAAGCAGAAATGGAAGAAGAAGACCAAG
ACGAAAACAAATTGGAAATTGGATTCGATGAAATAGCGAATATTGTGTCACGCTGGGCGAAGGTTCCGGTGTCCAAGCTA
ACAGAATCAGAATCACAAAAATATTTGTTCTTGGCTGACAATTTGAAAAAAGTTGTCATCGGTCAAGACAAGGCTATCGA
TTCTATTTCTAATGCAATTAAAAGAGCGCGTGTCGGACTCAAAAATCCGAACAAACCAATCGGTTCATTTGTATTTGTTG
GACCAACTGGTGTCGGTAAAACATACTTGGCGAAGAAACTTGCCAAAGAATTGTTCAATGATGAAAATGCGATGATTAGA
ATCGACATGACAGAATATATGGAAAAACATTCCGTTTCCAAATTGATAGGATCTCCTCCAGGATATGTTGGCCACGATGA
TGGCGGACAATTAACTGATATGGTGCGTACGAAACCATATTCTGTAATATTGTTTGACGAAATCGAAAAAGCCCATCCAG
ATGTTTTCAACACACTTTTACAAGTTTTGGATGACGGTAGACTTACAGATTCCAAAGGACGCGTGGTTAATTTCAAAGAT
ACTGTAATCATAATGACCTCAAACATTGGCGCAAGTGAACTTGAAAGCAAAAATGTAATTGGTTTTAATACTGCAGAAGA
TGTTGAGGTTGATGAATACAACAGAAACAAAGAAACTATAAACAATGCAATGAAGTCAATGTTCAAGCCAGAATTTATGA
ATAGATTAGACGATGTGATCGTGTTTAGCAATTTGAACAAGGAAAATGTAAAAGAAATTGCAGGACTTATGATGGATGAA
TTGGTCGATAGAATGGCGAAGAATGATTTGATAATTTCTTACGACGAAAAAATCTTGGATTATCTTGTGGACAAGGGATA
CGACAAGAAATTTGGAGCAAGACCTCTTGAAAGACTCATCAGGACAGATATTGAAAACGAACTTGCAGACAAGATTTTGA
ACGGAGATATCGACAATAACAGAAAAACGACTATAACTGTGGTTAACGACAAGGTTAGCTTCAGAAGATATGTAAGACGC
AAAAAGACTGTGAAACAATAA

Upstream 100 bases:

>100_bases
TGAAGCTTGAAAAATTTCGCGAAAACAATAATTTGAATCAAAACATTGGCGTTTTGAGAAGCGAAATTATCAAGGATACT
TTGGAAAGACAGGTGAAAAA

Downstream 100 bases:

>100_bases
TATGAAAAAGAAAACAAAATACGTGTGCAAAAATTGTGGCTATGAACAGGCCATGTGGATAGGAAAATGCCCCAGTTGTA
ACAGCTGGGGTTCTATGCAA

Product: ATP-dependent protease Clp ATP-binding subunit ClpC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 806; Mature: 806

Protein sequence:

>806_residues
MRKSDIYNLRTEAVYEAISLKHADLGVEHVLLAMFKFDFKASQYLKKHGGNYEKIRNLIIDELGYGDSDETNQRISPKLE
EIITQAVQLSNTYGERTITPEHIMAALCLDSSNYANHLMKRTGVDIMKLTAELRKYFFMKMKRERGDVNDNSANSSKPNE
IEKYTKNLNEMAKEGKIDPCIGREEEIERIIQVLLRRKKNNPVLIGNPGVGKTAIVEGLAVKIVKGDVNDIFKDKEILSL
DLAALLAGTKYRGDFEERIKKVIDTLSNSENKILFIDELHSLMGAGGAEGALDASNILKPSLARGDLQIIGATTINEYRK
TIEKDQAFERRLQTIMVDEPSVSDSIQVIEGLKDKYESHHHVLISDEAIKASVELSHRYLNDRYLPDKAIDLIDEAQSMV
RVKNFTGGKNYAKILEELEEEKQEAIQNSDFLLAAEKRDAIKEVEAEMEEEDQDENKLEIGFDEIANIVSRWAKVPVSKL
TESESQKYLFLADNLKKVVIGQDKAIDSISNAIKRARVGLKNPNKPIGSFVFVGPTGVGKTYLAKKLAKELFNDENAMIR
IDMTEYMEKHSVSKLIGSPPGYVGHDDGGQLTDMVRTKPYSVILFDEIEKAHPDVFNTLLQVLDDGRLTDSKGRVVNFKD
TVIIMTSNIGASELESKNVIGFNTAEDVEVDEYNRNKETINNAMKSMFKPEFMNRLDDVIVFSNLNKENVKEIAGLMMDE
LVDRMAKNDLIISYDEKILDYLVDKGYDKKFGARPLERLIRTDIENELADKILNGDIDNNRKTTITVVNDKVSFRRYVRR
KKTVKQ

Sequences:

>Translated_806_residues
MRKSDIYNLRTEAVYEAISLKHADLGVEHVLLAMFKFDFKASQYLKKHGGNYEKIRNLIIDELGYGDSDETNQRISPKLE
EIITQAVQLSNTYGERTITPEHIMAALCLDSSNYANHLMKRTGVDIMKLTAELRKYFFMKMKRERGDVNDNSANSSKPNE
IEKYTKNLNEMAKEGKIDPCIGREEEIERIIQVLLRRKKNNPVLIGNPGVGKTAIVEGLAVKIVKGDVNDIFKDKEILSL
DLAALLAGTKYRGDFEERIKKVIDTLSNSENKILFIDELHSLMGAGGAEGALDASNILKPSLARGDLQIIGATTINEYRK
TIEKDQAFERRLQTIMVDEPSVSDSIQVIEGLKDKYESHHHVLISDEAIKASVELSHRYLNDRYLPDKAIDLIDEAQSMV
RVKNFTGGKNYAKILEELEEEKQEAIQNSDFLLAAEKRDAIKEVEAEMEEEDQDENKLEIGFDEIANIVSRWAKVPVSKL
TESESQKYLFLADNLKKVVIGQDKAIDSISNAIKRARVGLKNPNKPIGSFVFVGPTGVGKTYLAKKLAKELFNDENAMIR
IDMTEYMEKHSVSKLIGSPPGYVGHDDGGQLTDMVRTKPYSVILFDEIEKAHPDVFNTLLQVLDDGRLTDSKGRVVNFKD
TVIIMTSNIGASELESKNVIGFNTAEDVEVDEYNRNKETINNAMKSMFKPEFMNRLDDVIVFSNLNKENVKEIAGLMMDE
LVDRMAKNDLIISYDEKILDYLVDKGYDKKFGARPLERLIRTDIENELADKILNGDIDNNRKTTITVVNDKVSFRRYVRR
KKTVKQ
>Mature_806_residues
MRKSDIYNLRTEAVYEAISLKHADLGVEHVLLAMFKFDFKASQYLKKHGGNYEKIRNLIIDELGYGDSDETNQRISPKLE
EIITQAVQLSNTYGERTITPEHIMAALCLDSSNYANHLMKRTGVDIMKLTAELRKYFFMKMKRERGDVNDNSANSSKPNE
IEKYTKNLNEMAKEGKIDPCIGREEEIERIIQVLLRRKKNNPVLIGNPGVGKTAIVEGLAVKIVKGDVNDIFKDKEILSL
DLAALLAGTKYRGDFEERIKKVIDTLSNSENKILFIDELHSLMGAGGAEGALDASNILKPSLARGDLQIIGATTINEYRK
TIEKDQAFERRLQTIMVDEPSVSDSIQVIEGLKDKYESHHHVLISDEAIKASVELSHRYLNDRYLPDKAIDLIDEAQSMV
RVKNFTGGKNYAKILEELEEEKQEAIQNSDFLLAAEKRDAIKEVEAEMEEEDQDENKLEIGFDEIANIVSRWAKVPVSKL
TESESQKYLFLADNLKKVVIGQDKAIDSISNAIKRARVGLKNPNKPIGSFVFVGPTGVGKTYLAKKLAKELFNDENAMIR
IDMTEYMEKHSVSKLIGSPPGYVGHDDGGQLTDMVRTKPYSVILFDEIEKAHPDVFNTLLQVLDDGRLTDSKGRVVNFKD
TVIIMTSNIGASELESKNVIGFNTAEDVEVDEYNRNKETINNAMKSMFKPEFMNRLDDVIVFSNLNKENVKEIAGLMMDE
LVDRMAKNDLIISYDEKILDYLVDKGYDKKFGARPLERLIRTDIENELADKILNGDIDNNRKTTITVVNDKVSFRRYVRR
KKTVKQ

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=300, Percent_Identity=36, Blast_Score=199, Evalue=6e-51,
Organism=Escherichia coli, GI1788943, Length=854, Percent_Identity=40.9836065573771, Blast_Score=608, Evalue=1e-175,
Organism=Escherichia coli, GI1787109, Length=787, Percent_Identity=38.1194409148666, Blast_Score=546, Evalue=1e-156,
Organism=Saccharomyces cerevisiae, GI6320464, Length=731, Percent_Identity=42.4076607387141, Blast_Score=567, Evalue=1e-162,
Organism=Saccharomyces cerevisiae, GI6323002, Length=391, Percent_Identity=39.6419437340153, Blast_Score=275, Evalue=2e-74,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 91320; Mature: 91320

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS50151 UVR ; PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKSDIYNLRTEAVYEAISLKHADLGVEHVLLAMFKFDFKASQYLKKHGGNYEKIRNLII
CCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
DELGYGDSDETNQRISPKLEEIITQAVQLSNTYGERTITPEHIMAALCLDSSNYANHLMK
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHH
RTGVDIMKLTAELRKYFFMKMKRERGDVNDNSANSSKPNEIEKYTKNLNEMAKEGKIDPC
HHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
IGREEEIERIIQVLLRRKKNNPVLIGNPGVGKTAIVEGLAVKIVKGDVNDIFKDKEILSL
CCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHEEEEEECCHHHHHCCHHHHHH
DLAALLAGTKYRGDFEERIKKVIDTLSNSENKILFIDELHSLMGAGGAEGALDASNILKP
HHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEHHHHHHHHCCCCCCCCCCHHHHCCC
SLARGDLQIIGATTINEYRKTIEKDQAFERRLQTIMVDEPSVSDSIQVIEGLKDKYESHH
CCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCC
HVLISDEAIKASVELSHRYLNDRYLPDKAIDLIDEAQSMVRVKNFTGGKNYAKILEELEE
EEEEECHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
EKQEAIQNSDFLLAAEKRDAIKEVEAEMEEEDQDENKLEIGFDEIANIVSRWAKVPVSKL
HHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCEEECHHHHHHHHHHHHHCCHHHH
TESESQKYLFLADNLKKVVIGQDKAIDSISNAIKRARVGLKNPNKPIGSFVFVGPTGVGK
HHCCCCCEEEEECCCHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCH
TYLAKKLAKELFNDENAMIRIDMTEYMEKHSVSKLIGSPPGYVGHDDGGQLTDMVRTKPY
HHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCC
SVILFDEIEKAHPDVFNTLLQVLDDGRLTDSKGRVVNFKDTVIIMTSNIGASELESKNVI
EEEEEHHHHHCCHHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEECCCCHHHHCCCCEE
GFNTAEDVEVDEYNRNKETINNAMKSMFKPEFMNRLDDVIVFSNLNKENVKEIAGLMMDE
CCCCCCCCCCHHCCCCHHHHHHHHHHHCCHHHHHHHHHEEEECCCCHHHHHHHHHHHHHH
LVDRMAKNDLIISYDEKILDYLVDKGYDKKFGARPLERLIRTDIENELADKILNGDIDNN
HHHHHHCCCEEEEEHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
RKTTITVVNDKVSFRRYVRRKKTVKQ
CEEEEEEECCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRKSDIYNLRTEAVYEAISLKHADLGVEHVLLAMFKFDFKASQYLKKHGGNYEKIRNLII
CCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
DELGYGDSDETNQRISPKLEEIITQAVQLSNTYGERTITPEHIMAALCLDSSNYANHLMK
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHH
RTGVDIMKLTAELRKYFFMKMKRERGDVNDNSANSSKPNEIEKYTKNLNEMAKEGKIDPC
HHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
IGREEEIERIIQVLLRRKKNNPVLIGNPGVGKTAIVEGLAVKIVKGDVNDIFKDKEILSL
CCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHEEEEEECCHHHHHCCHHHHHH
DLAALLAGTKYRGDFEERIKKVIDTLSNSENKILFIDELHSLMGAGGAEGALDASNILKP
HHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCEEEHHHHHHHHCCCCCCCCCCHHHHCCC
SLARGDLQIIGATTINEYRKTIEKDQAFERRLQTIMVDEPSVSDSIQVIEGLKDKYESHH
CCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCC
HVLISDEAIKASVELSHRYLNDRYLPDKAIDLIDEAQSMVRVKNFTGGKNYAKILEELEE
EEEEECHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
EKQEAIQNSDFLLAAEKRDAIKEVEAEMEEEDQDENKLEIGFDEIANIVSRWAKVPVSKL
HHHHHHCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCEEECHHHHHHHHHHHHHCCHHHH
TESESQKYLFLADNLKKVVIGQDKAIDSISNAIKRARVGLKNPNKPIGSFVFVGPTGVGK
HHCCCCCEEEEECCCHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCH
TYLAKKLAKELFNDENAMIRIDMTEYMEKHSVSKLIGSPPGYVGHDDGGQLTDMVRTKPY
HHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCC
SVILFDEIEKAHPDVFNTLLQVLDDGRLTDSKGRVVNFKDTVIIMTSNIGASELESKNVI
EEEEEHHHHHCCHHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEECCCCHHHHCCCCEE
GFNTAEDVEVDEYNRNKETINNAMKSMFKPEFMNRLDDVIVFSNLNKENVKEIAGLMMDE
CCCCCCCCCCHHCCCCHHHHHHHHHHHCCHHHHHHHHHEEEECCCCHHHHHHHHHHHHHH
LVDRMAKNDLIISYDEKILDYLVDKGYDKKFGARPLERLIRTDIENELADKILNGDIDNN
HHHHHHCCCEEEEEHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
RKTTITVVNDKVSFRRYVRRKKTVKQ
CEEEEEEECCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]