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The map label for this gene is hsdR [H]

Identifier: 169824028

GI number: 169824028

Start: 385249

End: 386145

Strand: Direct

Name: hsdR [H]

Synonym: FMG_0331

Alternate gene names: 169824028

Gene position: 385249-386145 (Clockwise)

Preceding gene: 169824027

Following gene: 169824029

Centisome position: 21.43

GC content: 32.55

Gene sequence:

>897_bases
GTGTGTTTCAGAGATTTGGAAAAGGCTACTGAAGATGCTATTAAAACATTTGGCGATGAAAATAGCGTGAATATTATTCT
TGAAAAAAGCTACGAAGAATATATGGAAGGTTTTACAGATGAGGAAACTGGCAAAGTAACCAGAGGATACAAGGATATTT
GTAATGAAATTGTTGCAAAATTCCCAGACACAACTGAGATTTTCTTGGAGGCTGATAAGAAGGAATTCGTACAACTTTTT
GGTGAATTGTTGAAATCGGAAAATATTCTGAAAAATTTCGATGAGTTTGAAAGTTTCGACAAAATTATTTCCGACAGATT
AATGCAAGACATGAAGAGTGTGTATGTTGATATTAGAGAAAATATCGTGAATTCAAGATGTTCAGGAGATTCTGAAGAAC
AACAGGTTGATTTCTCGGATGTAGAATTTCAAATTGATTTGTTGAAGACTGATGAGATAAACTTGGATTATATTTTGGCT
TTGATTTTGGAAAAATCCAAAGAACATGAGGATGTTGAAAACTTAAAAGCAGAAGTTCGTAGAGTTATAAGATCCAGTTT
GGGAACGAGAGCTAAGGAAGATTTGGTGATGGATTTTATTAACAAGACAAGATTATCAGAATTGAAAGATAATGATGATA
TATTGGAAACTTTCTATTCATTCGCAAGAAAAGAAAAAGAAAAGAAGGTTGAATCTCTTATCGAAGATGAAAAATTGAAA
GAAGGAGCATATCATTTTATCAACAAATCAATAGCGAAAGGTTTCGTGGATTACGCTGGTACTGGATTGGATAAAATTTT
GCCACCAACATCTCGTAGGCACGGTGCAAGAGAAAAGAAAAAACAAAATATTCTCGAAAAAATAGAAAAAATCGTAGAAG
TTTTTGTAGGAATATAA

Upstream 100 bases:

>100_bases
GCAAAGAATAGTTTGTGACACATAATTTATAAAGTACGTCACAACAGTAATAAAATTAAAAATAATAAAAAACTATAGAA
TTAAAACTTTTGGAAATATT

Downstream 100 bases:

>100_bases
TTTAATTGGGGAAGCTTTTTTAAGCTTTCCTTTTTCTTTTGAAAATATTAGAAATGTTGTAGGATTTTGTTGTTGAAGTG
AAAGGTCAAAGATGGTATAA

Product: hypothetical protein

Products: NA

Alternate protein names: R.EcoR124II [H]

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MCFRDLEKATEDAIKTFGDENSVNIILEKSYEEYMEGFTDEETGKVTRGYKDICNEIVAKFPDTTEIFLEADKKEFVQLF
GELLKSENILKNFDEFESFDKIISDRLMQDMKSVYVDIRENIVNSRCSGDSEEQQVDFSDVEFQIDLLKTDEINLDYILA
LILEKSKEHEDVENLKAEVRRVIRSSLGTRAKEDLVMDFINKTRLSELKDNDDILETFYSFARKEKEKKVESLIEDEKLK
EGAYHFINKSIAKGFVDYAGTGLDKILPPTSRRHGAREKKKQNILEKIEKIVEVFVGI

Sequences:

>Translated_298_residues
MCFRDLEKATEDAIKTFGDENSVNIILEKSYEEYMEGFTDEETGKVTRGYKDICNEIVAKFPDTTEIFLEADKKEFVQLF
GELLKSENILKNFDEFESFDKIISDRLMQDMKSVYVDIRENIVNSRCSGDSEEQQVDFSDVEFQIDLLKTDEINLDYILA
LILEKSKEHEDVENLKAEVRRVIRSSLGTRAKEDLVMDFINKTRLSELKDNDDILETFYSFARKEKEKKVESLIEDEKLK
EGAYHFINKSIAKGFVDYAGTGLDKILPPTSRRHGAREKKKQNILEKIEKIVEVFVGI
>Mature_298_residues
MCFRDLEKATEDAIKTFGDENSVNIILEKSYEEYMEGFTDEETGKVTRGYKDICNEIVAKFPDTTEIFLEADKKEFVQLF
GELLKSENILKNFDEFESFDKIISDRLMQDMKSVYVDIRENIVNSRCSGDSEEQQVDFSDVEFQIDLLKTDEINLDYILA
LILEKSKEHEDVENLKAEVRRVIRSSLGTRAKEDLVMDFINKTRLSELKDNDDILETFYSFARKEKEKKVESLIEDEKLK
EGAYHFINKSIAKGFVDYAGTGLDKILPPTSRRHGAREKKKQNILEKIEKIVEVFVGI

Specific function: The EcoR124/3 I enzyme recognizes 5'-GAAN(7)RTCG-3'. Subunit R is required for both nuclease and ATPase activities, but not for modification [H]

COG id: COG0610

COG function: function code V; Type I site-specific restriction-modification system, R (restriction) subunit and related helicases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase ATP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR014021
- InterPro:   IPR004473
- InterPro:   IPR006935
- InterPro:   IPR007409
- InterPro:   IPR022625 [H]

Pfam domain/function: PF12008 EcoR124_C; PF04313 HSDR_N; PF04851 ResIII [H]

EC number: =3.1.21.3 [H]

Molecular weight: Translated: 34614; Mature: 34614

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCFRDLEKATEDAIKTFGDENSVNIILEKSYEEYMEGFTDEETGKVTRGYKDICNEIVAK
CCHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
FPDTTEIFLEADKKEFVQLFGELLKSENILKNFDEFESFDKIISDRLMQDMKSVYVDIRE
CCCCHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NIVNSRCSGDSEEQQVDFSDVEFQIDLLKTDEINLDYILALILEKSKEHEDVENLKAEVR
HHHHHCCCCCCHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHH
RVIRSSLGTRAKEDLVMDFINKTRLSELKDNDDILETFYSFARKEKEKKVESLIEDEKLK
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EGAYHFINKSIAKGFVDYAGTGLDKILPPTSRRHGAREKKKQNILEKIEKIVEVFVGI
HHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MCFRDLEKATEDAIKTFGDENSVNIILEKSYEEYMEGFTDEETGKVTRGYKDICNEIVAK
CCHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
FPDTTEIFLEADKKEFVQLFGELLKSENILKNFDEFESFDKIISDRLMQDMKSVYVDIRE
CCCCHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NIVNSRCSGDSEEQQVDFSDVEFQIDLLKTDEINLDYILALILEKSKEHEDVENLKAEVR
HHHHHCCCCCCHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHH
RVIRSSLGTRAKEDLVMDFINKTRLSELKDNDDILETFYSFARKEKEKKVESLIEDEKLK
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EGAYHFINKSIAKGFVDYAGTGLDKILPPTSRRHGAREKKKQNILEKIEKIVEVFVGI
HHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2784505 [H]