Click here to switch to the map view.

The map label for this gene is hsdM [H]

Identifier: 169824025

GI number: 169824025

Start: 383675

End: 383902

Strand: Direct

Name: hsdM [H]

Synonym: FMG_0328

Alternate gene names: 169824025

Gene position: 383675-383902 (Clockwise)

Preceding gene: 169824024

Following gene: 169824026

Centisome position: 21.34

GC content: 36.4

Gene sequence:

>228_bases
TTGATATCCAATTATGCAAGTAATGCAGGAAAATCAGGGGGAGAATTCTTCACTCCACAAACAGTGTCCAAATTATTGGC
AAAGCTTGTAATGGACGGCAAAACAAGCATTAAAAAGGTATATGATCTGACATGTGAGGAACGTGTCATAATAGTGATGG
GTGCAGTTTGTGCTAATAAATCAACGGTTTCAGGAACTTTAACTAAATATATTTCGTACATTGCTTAG

Upstream 100 bases:

>100_bases
CCCAAAGGCAAAATGAAATAATTTCCAAAATAATGCTGACCCTGGCACACTTAACTTTGCAAAAACAAATGGAGACGTCA
TAGGAGATGCATACGAATAC

Downstream 100 bases:

>100_bases
AGTAATTAGGGTCTAATTGCTGTGAGCAGTGCATGAGAGGTAAGGACATTATCTCTTGAATAGTTGATAATTATCTAATA
CAATCATATTTAAGGTGATA

Product: putative type I site-specific deoxyribonuclease

Products: NA

Alternate protein names: M.EcoR124II [H]

Number of amino acids: Translated: 75; Mature: 75

Protein sequence:

>75_residues
MISNYASNAGKSGGEFFTPQTVSKLLAKLVMDGKTSIKKVYDLTCEERVIIVMGAVCANKSTVSGTLTKYISYIA

Sequences:

>Translated_75_residues
MISNYASNAGKSGGEFFTPQTVSKLLAKLVMDGKTSIKKVYDLTCEERVIIVMGAVCANKSTVSGTLTKYISYIA
>Mature_75_residues
MISNYASNAGKSGGEFFTPQTVSKLLAKLVMDGKTSIKKVYDLTCEERVIIVMGAVCANKSTVSGTLTKYISYIA

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities. The EcoR124/3 I enzyme recognizes 5'-GAAN(7)RTCG-3' [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022749
- InterPro:   IPR003356
- InterPro:   IPR002052
- InterPro:   IPR002296
- InterPro:   IPR004546 [H]

Pfam domain/function: PF12161 HsdM_N; PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 8044; Mature: 8044

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISNYASNAGKSGGEFFTPQTVSKLLAKLVMDGKTSIKKVYDLTCEERVIIVMGAVCANK
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEECCHHCCC
STVSGTLTKYISYIA
CCCHHHHHHHHHHHC
>Mature Secondary Structure
MISNYASNAGKSGGEFFTPQTVSKLLAKLVMDGKTSIKKVYDLTCEERVIIVMGAVCANK
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEECCHHCCC
STVSGTLTKYISYIA
CCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2784505 [H]