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The map label for this gene is rsbU [H]

Identifier: 169823978

GI number: 169823978

Start: 330968

End: 332074

Strand: Direct

Name: rsbU [H]

Synonym: FMG_0281

Alternate gene names: 169823978

Gene position: 330968-332074 (Clockwise)

Preceding gene: 169823977

Following gene: 169823979

Centisome position: 18.41

GC content: 33.69

Gene sequence:

>1107_bases
TTGGAGAAGAAATCAAGAGAAGGTGTTAGTGATTTCAAAGGATCTGATTATCAAGTTCTAAATTCGATGAAGGATTTAGT
CAGAGTAATAGATAAAGATGGGGTTATAATATTTGCTAATAAAAGCATGATAAATTCAATGCCTATCAATCCTATAGGCG
TGAACTGCTACTTGGATTACAGTGAAGATTTTCCAAAATGTTTGGCAGATAGAAAATACCGTTTGAACAGCACTATCAAA
GAAAAAAGAAAAATAAATGGTGTGGACTATTCCATAACTTCTTCTCCAGTTAGAAATAAAGATGGAGAGGTTGTAAGTAC
CGTCGAGGTTTTCAGAGATATTTCAAAAGAGGTTAAAACTCAGATTGATTTGATTAATGCGAACAAGGACATTAAGGATG
AAATAATCTTTGCAAAACACATTCAAAACAAAACTTTGCCTAGTAAGGGCGAGCATGTTGGGTTGGATTTGGATTACAGA
TATATTTCATCTAGGGATTTGTCTGGAGATATCATTGATTGCATCGACATTGATGAAAGATTTGTAGGAATTTATATTGC
TGATGTTGTGGGCCATGGTATTGCGGCATCAATTCTTACGATGTTTATTAGACAGACAATGAGGTATTTGGTAAGTAGAA
TTACAGATTCTAGGCCAAAAAGAGTGTTGAAGGATTTAAACACAACATTTACCGAACTTAATTTATCTGTAGATAAGTAT
TTTACGATTTTTTACGGATTATACGATAGAAAACTAAAAATATTCTCGTATGCAAATGCTGGTCACAATGGGATTCCATT
TTTGATTTCAAATGAGAAATTAGAAGAGTTAAAGGTTACGGGTCATCCTATTTCTCCAATGTTTGAAGGAATTGGCTTTA
CTCAAAGAGATATATTGCTATCCAGTGGCGATGAATTAATCATGTACACTGATGGAATAACTGAAACTAGAGGATTTGGG
AACGAATTTTACGGCGAAGAAAGACTGAAAAGAGATTTAATGAAGGTTCCAGATAAAAGAATCGAATACGTGCTAAGCGA
AGTGAATTCTTTTAGATTTTTGGAGCAAGATGATGATATTGTTTTAGTGAGCTTGAAGGTTCTATAG

Upstream 100 bases:

>100_bases
CGGCAAAAAATCATCTAAAAATAGAAAGATGTACAACGGAAATATGAAGTGTTATTTGTATCAATATTTTGGTCCAAGAC
CTAAATAGGAGGAGATTTCC

Downstream 100 bases:

>100_bases
GAGGAAATATGTTTAAGCTAGATTTTTCAAATACGACAAGTCATAATTCTGTAGACACTTTAAAAACAGAATCCGTAAAT
GCTTTGGAAAAGCTTTTAAA

Product: putative sigma factor SigB regulation protein

Products: NA

Alternate protein names: Sigma factor sigB regulation protein rsbU [H]

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MEKKSREGVSDFKGSDYQVLNSMKDLVRVIDKDGVIIFANKSMINSMPINPIGVNCYLDYSEDFPKCLADRKYRLNSTIK
EKRKINGVDYSITSSPVRNKDGEVVSTVEVFRDISKEVKTQIDLINANKDIKDEIIFAKHIQNKTLPSKGEHVGLDLDYR
YISSRDLSGDIIDCIDIDERFVGIYIADVVGHGIAASILTMFIRQTMRYLVSRITDSRPKRVLKDLNTTFTELNLSVDKY
FTIFYGLYDRKLKIFSYANAGHNGIPFLISNEKLEELKVTGHPISPMFEGIGFTQRDILLSSGDELIMYTDGITETRGFG
NEFYGEERLKRDLMKVPDKRIEYVLSEVNSFRFLEQDDDIVLVSLKVL

Sequences:

>Translated_368_residues
MEKKSREGVSDFKGSDYQVLNSMKDLVRVIDKDGVIIFANKSMINSMPINPIGVNCYLDYSEDFPKCLADRKYRLNSTIK
EKRKINGVDYSITSSPVRNKDGEVVSTVEVFRDISKEVKTQIDLINANKDIKDEIIFAKHIQNKTLPSKGEHVGLDLDYR
YISSRDLSGDIIDCIDIDERFVGIYIADVVGHGIAASILTMFIRQTMRYLVSRITDSRPKRVLKDLNTTFTELNLSVDKY
FTIFYGLYDRKLKIFSYANAGHNGIPFLISNEKLEELKVTGHPISPMFEGIGFTQRDILLSSGDELIMYTDGITETRGFG
NEFYGEERLKRDLMKVPDKRIEYVLSEVNSFRFLEQDDDIVLVSLKVL
>Mature_368_residues
MEKKSREGVSDFKGSDYQVLNSMKDLVRVIDKDGVIIFANKSMINSMPINPIGVNCYLDYSEDFPKCLADRKYRLNSTIK
EKRKINGVDYSITSSPVRNKDGEVVSTVEVFRDISKEVKTQIDLINANKDIKDEIIFAKHIQNKTLPSKGEHVGLDLDYR
YISSRDLSGDIIDCIDIDERFVGIYIADVVGHGIAASILTMFIRQTMRYLVSRITDSRPKRVLKDLNTTFTELNLSVDKY
FTIFYGLYDRKLKIFSYANAGHNGIPFLISNEKLEELKVTGHPISPMFEGIGFTQRDILLSSGDELIMYTDGITETRGFG
NEFYGEERLKRDLMKVPDKRIEYVLSEVNSFRFLEQDDDIVLVSLKVL

Specific function: Positive regulator of sigma-B activity. Dephosphorylates rsbV in response to environmental stress conveyed from the rsbXST module [H]

COG id: COG2208

COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017944
- InterPro:   IPR001932
- InterPro:   IPR014787
- InterPro:   IPR010822
- ProDom:   PD685490 [H]

Pfam domain/function: PF08673 RsbU_N; PF07228 SpoIIE [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 42093; Mature: 42093

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKKSREGVSDFKGSDYQVLNSMKDLVRVIDKDGVIIFANKSMINSMPINPIGVNCYLDY
CCCCCCCCCHHCCCCHHHHHHHHHHHHHHHCCCCEEEEECCHHHCCCCCCCEEEEEEECC
SEDFPKCLADRKYRLNSTIKEKRKINGVDYSITSSPVRNKDGEVVSTVEVFRDISKEVKT
CCCHHHHHHCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHH
QIDLINANKDIKDEIIFAKHIQNKTLPSKGEHVGLDLDYRYISSRDLSGDIIDCIDIDER
HHEEECCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCCCCCCCEEEEEECCCH
FVGIYIADVVGHGIAASILTMFIRQTMRYLVSRITDSRPKRVLKDLNTTFTELNLSVDKY
HHHEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHEECCHHHH
FTIFYGLYDRKLKIFSYANAGHNGIPFLISNEKLEELKVTGHPISPMFEGIGFTQRDILL
HHHHHHHHCCEEEEEEECCCCCCCCCEEECCCCHHHHEECCCCCCHHHHCCCCCHHHEEE
SSGDELIMYTDGITETRGFGNEFYGEERLKRDLMKVPDKRIEYVLSEVNSFRFLEQDDDI
ECCCEEEEEECCCCCCCCCCCHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCE
VLVSLKVL
EEEEEEEC
>Mature Secondary Structure
MEKKSREGVSDFKGSDYQVLNSMKDLVRVIDKDGVIIFANKSMINSMPINPIGVNCYLDY
CCCCCCCCCHHCCCCHHHHHHHHHHHHHHHCCCCEEEEECCHHHCCCCCCCEEEEEEECC
SEDFPKCLADRKYRLNSTIKEKRKINGVDYSITSSPVRNKDGEVVSTVEVFRDISKEVKT
CCCHHHHHHCCCHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHH
QIDLINANKDIKDEIIFAKHIQNKTLPSKGEHVGLDLDYRYISSRDLSGDIIDCIDIDER
HHEEECCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCCCCCCCEEEEEECCCH
FVGIYIADVVGHGIAASILTMFIRQTMRYLVSRITDSRPKRVLKDLNTTFTELNLSVDKY
HHHEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHEECCHHHH
FTIFYGLYDRKLKIFSYANAGHNGIPFLISNEKLEELKVTGHPISPMFEGIGFTQRDILL
HHHHHHHHCCEEEEEEECCCCCCCCCEEECCCCHHHHEECCCCCCHHHHCCCCCHHHEEE
SSGDELIMYTDGITETRGFGNEFYGEERLKRDLMKVPDKRIEYVLSEVNSFRFLEQDDDI
ECCCEEEEEECCCCCCCCCCCHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCE
VLVSLKVL
EEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8002610; 8002609; 9384377; 8824586; 9786195; 12499568 [H]