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The map label for this gene is dinB [H]

Identifier: 169823974

GI number: 169823974

Start: 327244

End: 328287

Strand: Direct

Name: dinB [H]

Synonym: FMG_0277

Alternate gene names: 169823974

Gene position: 327244-328287 (Clockwise)

Preceding gene: 169823973

Following gene: 169823975

Centisome position: 18.2

GC content: 32.28

Gene sequence:

>1044_bases
ATGGATTTAAATTTTTTGCATTTTGATTTGGATGCTTTCTTTGCGTCTTGTGAAATTCTCGATAATCCAAAATTGAAACA
CGTCCCTATGGTTGTTGGTGGAAGAAGTCAGAGAGGGATTATTACTACTGCAAATTACGAAGCAAGAAAATACGGTCTAC
ATTCTGCGATGCCAATATTTCAAGCGAAAAAAATTGTTCCAAACCTTGTTATAGTTGCTCCTGATTTCGAGAAATACAGA
AGAAATAGCGAGAAAGTTTTCAAGGTATTGTCGAGCTTTTCTAATAAGATTCAAAAAATGAGTATAGATGAAGGTTGCAT
GGATATTTCTCATATTAGAATGGATAGATTAGAATTGGCAAACTTAATCCAAGAAAATGTTAGGATAAAAACAGGACTAT
CTATTTCAATTGGAATTAGCTACAACATGAGCCTTGCAAAGCTTGCGTCAGATTGGAACAAGCCTCATGGAATCAAAATC
ATCACACAAGATGATATTCCAAATATTTTGTTGGATTTAAAGGTTGGTAAGATTCAAGGAATCGGGAGAAAATCTGAAGA
AAAATTAAATAAAATTGGCATTAAAAAAGTAAGTGATTTGTACGATTTATCCAGAAATAATTTGAGAGAATTGTTCGGTA
AGTTTGGTGAAGTAATCTACGATAGAATTCGAGGCATTGATGAAAGACAGTTGGATTTGTCGAGAATTAGAAAATCTATC
GGAGTGGAGTATACTTTTGAACGTGATTTGAAAAATTACAATGAATTATTAAATAAAGCTAGTGAGTTCAGCGAAGAATT
AAGTGATGATCTTCATAAGAAAAATATTAAAGCAAAAACTATTAGAATTAAAATAAAACTCAATGATTTTTCCGTGATTA
CAAAATCGATGACTTTAGAAGAATACATTAGTGATTCTAGCGATATTTTTAGGATTGTAAAGTATCTTGTGGTTAATACG
AAGATAGAAAAGTCTGTGAGGCTTTTCGGAATTACGGCGGCAAACCTGAGCGACACGACTTTTGAGCAATTAAAATTTTT
GTAG

Upstream 100 bases:

>100_bases
TTCACTAAAATCGTACGATGCATGGATATCATCAAACAACTTAGAAATTAACGATTAAGCTCTCAATAATGAGAGCTTTT
TTAGTAGAAAGGGGTGTGTT

Downstream 100 bases:

>100_bases
TAAAAAACTTTACACAATACCTTGCAATATATACTACCGTGTATTATAATATAATCAGGAGGTAAGATATGAACACACAA
TTAAAAAAAGGGATTTTAGA

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MDLNFLHFDLDAFFASCEILDNPKLKHVPMVVGGRSQRGIITTANYEARKYGLHSAMPIFQAKKIVPNLVIVAPDFEKYR
RNSEKVFKVLSSFSNKIQKMSIDEGCMDISHIRMDRLELANLIQENVRIKTGLSISIGISYNMSLAKLASDWNKPHGIKI
ITQDDIPNILLDLKVGKIQGIGRKSEEKLNKIGIKKVSDLYDLSRNNLRELFGKFGEVIYDRIRGIDERQLDLSRIRKSI
GVEYTFERDLKNYNELLNKASEFSEELSDDLHKKNIKAKTIRIKIKLNDFSVITKSMTLEEYISDSSDIFRIVKYLVVNT
KIEKSVRLFGITAANLSDTTFEQLKFL

Sequences:

>Translated_347_residues
MDLNFLHFDLDAFFASCEILDNPKLKHVPMVVGGRSQRGIITTANYEARKYGLHSAMPIFQAKKIVPNLVIVAPDFEKYR
RNSEKVFKVLSSFSNKIQKMSIDEGCMDISHIRMDRLELANLIQENVRIKTGLSISIGISYNMSLAKLASDWNKPHGIKI
ITQDDIPNILLDLKVGKIQGIGRKSEEKLNKIGIKKVSDLYDLSRNNLRELFGKFGEVIYDRIRGIDERQLDLSRIRKSI
GVEYTFERDLKNYNELLNKASEFSEELSDDLHKKNIKAKTIRIKIKLNDFSVITKSMTLEEYISDSSDIFRIVKYLVVNT
KIEKSVRLFGITAANLSDTTFEQLKFL
>Mature_347_residues
MDLNFLHFDLDAFFASCEILDNPKLKHVPMVVGGRSQRGIITTANYEARKYGLHSAMPIFQAKKIVPNLVIVAPDFEKYR
RNSEKVFKVLSSFSNKIQKMSIDEGCMDISHIRMDRLELANLIQENVRIKTGLSISIGISYNMSLAKLASDWNKPHGIKI
ITQDDIPNILLDLKVGKIQGIGRKSEEKLNKIGIKKVSDLYDLSRNNLRELFGKFGEVIYDRIRGIDERQLDLSRIRKSI
GVEYTFERDLKNYNELLNKASEFSEELSDDLHKKNIKAKTIRIKIKLNDFSVITKSMTLEEYISDSSDIFRIVKYLVVNT
KIEKSVRLFGITAANLSDTTFEQLKFL

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=337, Percent_Identity=26.1127596439169, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI7706681, Length=338, Percent_Identity=26.0355029585799, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI154350220, Length=324, Percent_Identity=27.4691358024691, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI7705344, Length=105, Percent_Identity=42.8571428571429, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI5729982, Length=393, Percent_Identity=23.9185750636132, Blast_Score=94, Evalue=3e-19,
Organism=Escherichia coli, GI1786425, Length=345, Percent_Identity=32.7536231884058, Blast_Score=204, Evalue=6e-54,
Organism=Escherichia coli, GI1787432, Length=299, Percent_Identity=26.0869565217391, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI193205700, Length=403, Percent_Identity=29.5285359801489, Blast_Score=150, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI193205702, Length=350, Percent_Identity=28, Blast_Score=103, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI17537959, Length=297, Percent_Identity=25.5892255892256, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI115534089, Length=124, Percent_Identity=33.8709677419355, Blast_Score=71, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6324921, Length=203, Percent_Identity=28.5714285714286, Blast_Score=73, Evalue=6e-14,
Organism=Drosophila melanogaster, GI19923006, Length=334, Percent_Identity=24.251497005988, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI21355641, Length=284, Percent_Identity=26.056338028169, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24644984, Length=284, Percent_Identity=26.056338028169, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24668444, Length=249, Percent_Identity=27.3092369477912, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 39834; Mature: 39834

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLNFLHFDLDAFFASCEILDNPKLKHVPMVVGGRSQRGIITTANYEARKYGLHSAMPIF
CCCCEEEEEHHHHHHHHHCCCCCCCEECCEEECCCCCCCEEEECCCCHHHHCCHHCCHHH
QAKKIVPNLVIVAPDFEKYRRNSEKVFKVLSSFSNKIQKMSIDEGCMDISHIRMDRLELA
HHHHHCCCEEEECCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
NLIQENVRIKTGLSISIGISYNMSLAKLASDWNKPHGIKIITQDDIPNILLDLKVGKIQG
HHHHHCCEEEECCEEEEEEEECCHHHHHHHHCCCCCCEEEEECCCCCCEEEEEEEHHCCC
IGRKSEEKLNKIGIKKVSDLYDLSRNNLRELFGKFGEVIYDRIRGIDERQLDLSRIRKSI
CCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
GVEYTFERDLKNYNELLNKASEFSEELSDDLHKKNIKAKTIRIKIKLNDFSVITKSMTLE
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCHHHHHHHHHHH
EYISDSSDIFRIVKYLVVNTKIEKSVRLFGITAANLSDTTFEQLKFL
HHHCCCHHHHHHHHHHHHCCHHHCCEEEEEEEECCCCCHHHHHHHCC
>Mature Secondary Structure
MDLNFLHFDLDAFFASCEILDNPKLKHVPMVVGGRSQRGIITTANYEARKYGLHSAMPIF
CCCCEEEEEHHHHHHHHHCCCCCCCEECCEEECCCCCCCEEEECCCCHHHHCCHHCCHHH
QAKKIVPNLVIVAPDFEKYRRNSEKVFKVLSSFSNKIQKMSIDEGCMDISHIRMDRLELA
HHHHHCCCEEEECCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
NLIQENVRIKTGLSISIGISYNMSLAKLASDWNKPHGIKIITQDDIPNILLDLKVGKIQG
HHHHHCCEEEECCEEEEEEEECCHHHHHHHHCCCCCCEEEEECCCCCCEEEEEEEHHCCC
IGRKSEEKLNKIGIKKVSDLYDLSRNNLRELFGKFGEVIYDRIRGIDERQLDLSRIRKSI
CCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
GVEYTFERDLKNYNELLNKASEFSEELSDDLHKKNIKAKTIRIKIKLNDFSVITKSMTLE
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCHHHHHHHHHHH
EYISDSSDIFRIVKYLVVNTKIEKSVRLFGITAANLSDTTFEQLKFL
HHHCCCHHHHHHHHHHHHCCHHHCCEEEEEEEECCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]