Click here to switch to the map view.

The map label for this gene is mmpL1 [H]

Identifier: 169629656

GI number: 169629656

Start: 2613452

End: 2615449

Strand: Reverse

Name: mmpL1 [H]

Synonym: MAB_2570c

Alternate gene names: 169629656

Gene position: 2615449-2613452 (Counterclockwise)

Preceding gene: 169629657

Following gene: 169629655

Centisome position: 51.62

GC content: 60.76

Gene sequence:

>1998_bases
GTGCGCAGCGTCGCGCACGTCGTCATCGGATCGGGTGTGGCGATCTCGGGTGCGTGCCTGTGCCTGAGCCTCACTACGCT
CGACTACTTCCGCACCCTGGGCCCGCCGTGCTTCGCAGCGATGGTGGTGGCTGTTATCTCGGCACTCACGCTGGGGCCGG
CGTTGTTGACGCTGGGCAGCAAGGTGCCGTGGCTGTCCGAGCCCGCAAAAACCAGCCCGGCCTGGCGCAAGCTGGGTACG
GCGATCGCCAAGTGGCCGGCGGCGATGATCGCGGTTGCGGCCCTGGTGATCCCACTGTGCATCGCCAACCTGGCCAACTA
CACGGTGAGCTACAACGATCGCGACTACGCGCCCAAGAGCGTCGAATCCTCCCAAGGCTATGCGGCAGCCGACCGGCATT
TCCAGCCGAGCCAGCTCTCCATCGACACCCTGTACATCAAGGCCGACCACGATATGCGCAACACCACCGACATGATCAGC
CTGGATCGCCTCGCCAAAAATATCGTGCGCACACCGGGTATTTCGATGGTGCAGAGCATCACCCGACCCAATGGACGGCC
GCTGGAACACGCGTCACTGCCGTATGCGATGGGTTCGATGGGAACCAAGATCGGTCAGAATCTCGGCTTCTTGAAAGACC
GCGTCGCCGATATCGACGCCATCGCCGCCCGCATGGGCGACATGATTGCCTCGACCGAAAAGATGGCGGGCCTCACACGG
CAGTTGGCTGAAGGCGCCCAGATCTCCACAGAGGCCGCTAAGGGGCTCAAGGAAGTAATGGAGAAGATGCGCGACAACAT
AGCCAACTTCGATGACTCCTTCCGCCCGATACGCAACTATCTGTATTGGGAGCCACACTGCTTCGACATCCCGATGTGTT
GGGCCATGCGCTCGCTGAACGAGTCGCTCGACAGCATCGACGAAACGACGCAATACTTAGGGCCGATGGTCGATGGTCTG
ACAAAGATCTCCACCGCCACCCCGCAGATGATCACCCAGCTCAACGCAATGGTGCAGAACATGACCGTCATGCAACGGCT
GACACTGACCACGCAGAGCCTGCTCCATGCAACCGTCACCCAGATGGAGCCGATGGTCAACCCGATGGTCGACATGGCGC
AGGCGTTCGACAACGCCAAGAACGACGATTTCTTCTTCCTGCCACCGGATTCCTTCAAAACCAAGGACTTTCAGTCTGGG
TTGAAATTCATGATGACACCCGATGGCAAGGGCGCCCGCATCATGATTTATCACCAGGGTGAAGCGATGAGCCCCGAGGG
CATCGATCAGATCCGGCGCGCCGATGCCGCCGCTCACGAGGCCATCAAGGGCACCTCGTTGTCGGGCGTAGAGCTTCTCA
TGGCCGGCTCATCCGCTAATTTCCGCGATGTTCAAGCGTTTTCCATGAACGACATCCTGACGATGATGCTGGCCACATTC
GGATTGGTGTTCCTGATCGTGATGGCCATCACCCGTACCCTGGCCGGTTCGGTGATCGTGCTGATCACTGTGGTGCTGTC
TTTTCTCGGCTCACTGGGACTGGCAGTCTTCATCTGGGAAACTCTGCTCGGTATCGAATTACATTGGCTCACACTGCCCA
TCGCCTTCATCGTGCTCGTCGGCGTGGGATGCGACTACAACCTGCTGCTGCTCTCCCGGTATCGGGAAGAGTTGTCGGCG
GGTATTCGCACGGGCCTGATCCGCACTATTGCAGGTTCGGGCAATGTCGCTGTCACCGCGGCGTTCGTACTCGCCGGCAC
CATGCTCGCCATGCTCTCCAGCGACGTGGTCAACATCGGCCAGGCCGGAGCAACCATCTGCATCGGACTGGTCTTCGACA
TGATGATCGTGCGCCTCTTCCTGGTCATGCCGCTGGCCCGGCTACTCGGCCCGTGGTTCTGGTGGCCGCAGAAACTACCC
CGGCGCCAGCCCGTTCAACTCAGGGGCACACCGGGCCCCGGGCCACAAGCCATCAGCGAGGCCGGCCCCCACGTGTAG

Upstream 100 bases:

>100_bases
TGGTTCTCGGTGTGGCCACCGATTACGGCATCTTCTATCTTGGTCGCTTTCAGGAGGCCCTCCGGTCCGGGAGGACCGTG
AGTCGGCGTACTACACCTCG

Downstream 100 bases:

>100_bases
ATGCACGGTCATGACCAAAGGCATCCACGTGCAAGGGCGAGCAGTCCCGACCGGCATCCGAACTTGAGCAACGTGATCTG
CGCACACTCCAGCGGATGTA

Product: MmpL family membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 665; Mature: 665

Protein sequence:

>665_residues
MRSVAHVVIGSGVAISGACLCLSLTTLDYFRTLGPPCFAAMVVAVISALTLGPALLTLGSKVPWLSEPAKTSPAWRKLGT
AIAKWPAAMIAVAALVIPLCIANLANYTVSYNDRDYAPKSVESSQGYAAADRHFQPSQLSIDTLYIKADHDMRNTTDMIS
LDRLAKNIVRTPGISMVQSITRPNGRPLEHASLPYAMGSMGTKIGQNLGFLKDRVADIDAIAARMGDMIASTEKMAGLTR
QLAEGAQISTEAAKGLKEVMEKMRDNIANFDDSFRPIRNYLYWEPHCFDIPMCWAMRSLNESLDSIDETTQYLGPMVDGL
TKISTATPQMITQLNAMVQNMTVMQRLTLTTQSLLHATVTQMEPMVNPMVDMAQAFDNAKNDDFFFLPPDSFKTKDFQSG
LKFMMTPDGKGARIMIYHQGEAMSPEGIDQIRRADAAAHEAIKGTSLSGVELLMAGSSANFRDVQAFSMNDILTMMLATF
GLVFLIVMAITRTLAGSVIVLITVVLSFLGSLGLAVFIWETLLGIELHWLTLPIAFIVLVGVGCDYNLLLLSRYREELSA
GIRTGLIRTIAGSGNVAVTAAFVLAGTMLAMLSSDVVNIGQAGATICIGLVFDMMIVRLFLVMPLARLLGPWFWWPQKLP
RRQPVQLRGTPGPGPQAISEAGPHV

Sequences:

>Translated_665_residues
MRSVAHVVIGSGVAISGACLCLSLTTLDYFRTLGPPCFAAMVVAVISALTLGPALLTLGSKVPWLSEPAKTSPAWRKLGT
AIAKWPAAMIAVAALVIPLCIANLANYTVSYNDRDYAPKSVESSQGYAAADRHFQPSQLSIDTLYIKADHDMRNTTDMIS
LDRLAKNIVRTPGISMVQSITRPNGRPLEHASLPYAMGSMGTKIGQNLGFLKDRVADIDAIAARMGDMIASTEKMAGLTR
QLAEGAQISTEAAKGLKEVMEKMRDNIANFDDSFRPIRNYLYWEPHCFDIPMCWAMRSLNESLDSIDETTQYLGPMVDGL
TKISTATPQMITQLNAMVQNMTVMQRLTLTTQSLLHATVTQMEPMVNPMVDMAQAFDNAKNDDFFFLPPDSFKTKDFQSG
LKFMMTPDGKGARIMIYHQGEAMSPEGIDQIRRADAAAHEAIKGTSLSGVELLMAGSSANFRDVQAFSMNDILTMMLATF
GLVFLIVMAITRTLAGSVIVLITVVLSFLGSLGLAVFIWETLLGIELHWLTLPIAFIVLVGVGCDYNLLLLSRYREELSA
GIRTGLIRTIAGSGNVAVTAAFVLAGTMLAMLSSDVVNIGQAGATICIGLVFDMMIVRLFLVMPLARLLGPWFWWPQKLP
RRQPVQLRGTPGPGPQAISEAGPHV
>Mature_665_residues
MRSVAHVVIGSGVAISGACLCLSLTTLDYFRTLGPPCFAAMVVAVISALTLGPALLTLGSKVPWLSEPAKTSPAWRKLGT
AIAKWPAAMIAVAALVIPLCIANLANYTVSYNDRDYAPKSVESSQGYAAADRHFQPSQLSIDTLYIKADHDMRNTTDMIS
LDRLAKNIVRTPGISMVQSITRPNGRPLEHASLPYAMGSMGTKIGQNLGFLKDRVADIDAIAARMGDMIASTEKMAGLTR
QLAEGAQISTEAAKGLKEVMEKMRDNIANFDDSFRPIRNYLYWEPHCFDIPMCWAMRSLNESLDSIDETTQYLGPMVDGL
TKISTATPQMITQLNAMVQNMTVMQRLTLTTQSLLHATVTQMEPMVNPMVDMAQAFDNAKNDDFFFLPPDSFKTKDFQSG
LKFMMTPDGKGARIMIYHQGEAMSPEGIDQIRRADAAAHEAIKGTSLSGVELLMAGSSANFRDVQAFSMNDILTMMLATF
GLVFLIVMAITRTLAGSVIVLITVVLSFLGSLGLAVFIWETLLGIELHWLTLPIAFIVLVGVGCDYNLLLLSRYREELSA
GIRTGLIRTIAGSGNVAVTAAFVLAGTMLAMLSSDVVNIGQAGATICIGLVFDMMIVRLFLVMPLARLLGPWFWWPQKLP
RRQPVQLRGTPGPGPQAISEAGPHV

Specific function: Unknown

COG id: COG2409

COG function: function code R; Predicted drug exporters of the RND superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mmpL family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004707
- InterPro:   IPR004869 [H]

Pfam domain/function: PF03176 MMPL [H]

EC number: NA

Molecular weight: Translated: 72227; Mature: 72227

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSVAHVVIGSGVAISGACLCLSLTTLDYFRTLGPPCFAAMVVAVISALTLGPALLTLGS
CCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
KVPWLSEPAKTSPAWRKLGTAIAKWPAAMIAVAALVIPLCIANLANYTVSYNDRDYAPKS
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCCCC
VESSQGYAAADRHFQPSQLSIDTLYIKADHDMRNTTDMISLDRLAKNIVRTPGISMVQSI
CCCCCCCCHHCCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHH
TRPNGRPLEHASLPYAMGSMGTKIGQNLGFLKDRVADIDAIAARMGDMIASTEKMAGLTR
HCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLAEGAQISTEAAKGLKEVMEKMRDNIANFDDSFRPIRNYLYWEPHCFDIPMCWAMRSLN
HHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHH
ESLDSIDETTQYLGPMVDGLTKISTATPQMITQLNAMVQNMTVMQRLTLTTQSLLHATVT
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QMEPMVNPMVDMAQAFDNAKNDDFFFLPPDSFKTKDFQSGLKFMMTPDGKGARIMIYHQG
HHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHCCCCEEECCCCCCCEEEEEECC
EAMSPEGIDQIRRADAAAHEAIKGTSLSGVELLMAGSSANFRDVQAFSMNDILTMMLATF
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
GLVFLIVMAITRTLAGSVIVLITVVLSFLGSLGLAVFIWETLLGIELHWLTLPIAFIVLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVGCDYNLLLLSRYREELSAGIRTGLIRTIAGSGNVAVTAAFVLAGTMLAMLSSDVVNIG
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
QAGATICIGLVFDMMIVRLFLVMPLARLLGPWFWWPQKLPRRQPVQLRGTPGPGPQAISE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCEEECCCCCCHHHHHH
AGPHV
CCCCC
>Mature Secondary Structure
MRSVAHVVIGSGVAISGACLCLSLTTLDYFRTLGPPCFAAMVVAVISALTLGPALLTLGS
CCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
KVPWLSEPAKTSPAWRKLGTAIAKWPAAMIAVAALVIPLCIANLANYTVSYNDRDYAPKS
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCCCC
VESSQGYAAADRHFQPSQLSIDTLYIKADHDMRNTTDMISLDRLAKNIVRTPGISMVQSI
CCCCCCCCHHCCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHH
TRPNGRPLEHASLPYAMGSMGTKIGQNLGFLKDRVADIDAIAARMGDMIASTEKMAGLTR
HCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLAEGAQISTEAAKGLKEVMEKMRDNIANFDDSFRPIRNYLYWEPHCFDIPMCWAMRSLN
HHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHH
ESLDSIDETTQYLGPMVDGLTKISTATPQMITQLNAMVQNMTVMQRLTLTTQSLLHATVT
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QMEPMVNPMVDMAQAFDNAKNDDFFFLPPDSFKTKDFQSGLKFMMTPDGKGARIMIYHQG
HHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCHHHCCCCEEECCCCCCCEEEEEECC
EAMSPEGIDQIRRADAAAHEAIKGTSLSGVELLMAGSSANFRDVQAFSMNDILTMMLATF
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
GLVFLIVMAITRTLAGSVIVLITVVLSFLGSLGLAVFIWETLLGIELHWLTLPIAFIVLV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVGCDYNLLLLSRYREELSAGIRTGLIRTIAGSGNVAVTAAFVLAGTMLAMLSSDVVNIG
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHC
QAGATICIGLVFDMMIVRLFLVMPLARLLGPWFWWPQKLPRRQPVQLRGTPGPGPQAISE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCEEECCCCCCHHHHHH
AGPHV
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]