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The map label for this gene is mer [H]

Identifier: 169629517

GI number: 169629517

Start: 2487719

End: 2488702

Strand: Reverse

Name: mer [H]

Synonym: MAB_2431c

Alternate gene names: 169629517

Gene position: 2488702-2487719 (Counterclockwise)

Preceding gene: 169629518

Following gene: 169629516

Centisome position: 49.11

GC content: 64.53

Gene sequence:

>984_bases
GTGACCATTCGGCTCGGATATCAGATTCCCAACTTCTCCTACGGCACCGGTGTCGCCGAACTCTTCCCCACCGTTGTCAA
ACAGGTGCGCGAGGCAGAGGCGTCGGGCTTCGACACGGTCTTCGTGATGGATCACTTCTATCAGCTGCCCATGATCGGCA
CCCCAGACCAGCCCATGCTCGAGGCGTACACGGCGCTGGGCGCTCTCGCGAGTGCCACCAGCACCATCCAGCTCTCCACG
CTGGTCACCGGCAACACGTACCGCAACCCGGCCCTGCTCGCCAAGGCGGTCACCACGCTGGACGTCGTCAGCGGCGGGCG
CGCGATCCTGGGCATCGGTGCCGGATGGTTCGAACTGGAGCATCAGCAGCTCGGATTCGAGTTCGGCACCTTCACCGACC
GCTTCGAGCGGTTGACCGAGGCCTTGGAGATCATTCCGCCGATGCTCCGCGGGGAGCGTCCCACCTTCGAGGGCAAGTAC
TACCGCACCGAATCGGCGCTTAACGAGCCGCGGCTCCGGCCGAACATTCCGATCATGATCGGCGGCAGCGGCGAGAAGAA
GACCTTCGGTTTAGCGGTCAAGTACGCCGACCACCTGAACCTGCTCAGCTCGCTGGATGAGATTCCACACAAGCTGACGG
TGCTGCGGCAGCGCTGCGAAGAGGCCGGGCGCGATCCGTCGACGCTGGAAACGTCGGCCTTCTTCTCCGTCTTCATCGAT
GACGATTCGGCGACGGCATGGAAACTGGCTGCCTCGCAGCTGAGCCAGAACGGCATCGATCTGGACACCCTGCCGGACGA
GGCCCGGGCTCAGGTGCTCGGGCGCACCCTGGTGGGCAACCCCGAGGAGATCGCCGAGCAGGTGCAGACCCGGGTCCTGG
ACCAGGGCATCGACTCCGTCACCCTGAACGCGCCCGCCACCGGGCATCTGCCGGGTGTGGTGGAGCTGATCGGTAACACT
CTTCGCCCGCTGTTCAAGAACTAG

Upstream 100 bases:

>100_bases
AGCTGACTCAAGCTGGAGTGCACTCCAGCTTGATATGCCGAATTGCCTTGCAGGGCAAGACCGTAATGCCACACCGGCGG
ATCGGGCGTAGGCTGGCCGA

Downstream 100 bases:

>100_bases
TTGACGGCATCATCGCCCGCACCTCACCGGCCTTCGGGCAGGATGGGTGATGTGGAGATACCGTTCAGTTTGCGACCCGC
GGCCTCGGCCGTCGCAGCCC

Product: luciferase-like oxidoreductase

Products: NA

Alternate protein names: Coenzyme F420-dependent N(5),N(10)-methylenetetrahydromethanopterin reductase; Methylene-H(4)MPT reductase [H]

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MTIRLGYQIPNFSYGTGVAELFPTVVKQVREAEASGFDTVFVMDHFYQLPMIGTPDQPMLEAYTALGALASATSTIQLST
LVTGNTYRNPALLAKAVTTLDVVSGGRAILGIGAGWFELEHQQLGFEFGTFTDRFERLTEALEIIPPMLRGERPTFEGKY
YRTESALNEPRLRPNIPIMIGGSGEKKTFGLAVKYADHLNLLSSLDEIPHKLTVLRQRCEEAGRDPSTLETSAFFSVFID
DDSATAWKLAASQLSQNGIDLDTLPDEARAQVLGRTLVGNPEEIAEQVQTRVLDQGIDSVTLNAPATGHLPGVVELIGNT
LRPLFKN

Sequences:

>Translated_327_residues
MTIRLGYQIPNFSYGTGVAELFPTVVKQVREAEASGFDTVFVMDHFYQLPMIGTPDQPMLEAYTALGALASATSTIQLST
LVTGNTYRNPALLAKAVTTLDVVSGGRAILGIGAGWFELEHQQLGFEFGTFTDRFERLTEALEIIPPMLRGERPTFEGKY
YRTESALNEPRLRPNIPIMIGGSGEKKTFGLAVKYADHLNLLSSLDEIPHKLTVLRQRCEEAGRDPSTLETSAFFSVFID
DDSATAWKLAASQLSQNGIDLDTLPDEARAQVLGRTLVGNPEEIAEQVQTRVLDQGIDSVTLNAPATGHLPGVVELIGNT
LRPLFKN
>Mature_326_residues
TIRLGYQIPNFSYGTGVAELFPTVVKQVREAEASGFDTVFVMDHFYQLPMIGTPDQPMLEAYTALGALASATSTIQLSTL
VTGNTYRNPALLAKAVTTLDVVSGGRAILGIGAGWFELEHQQLGFEFGTFTDRFERLTEALEIIPPMLRGERPTFEGKYY
RTESALNEPRLRPNIPIMIGGSGEKKTFGLAVKYADHLNLLSSLDEIPHKLTVLRQRCEEAGRDPSTLETSAFFSVFIDD
DSATAWKLAASQLSQNGIDLDTLPDEARAQVLGRTLVGNPEEIAEQVQTRVLDQGIDSVTLNAPATGHLPGVVELIGNTL
RPLFKN

Specific function: Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mer family [H]

Homologues:

Organism=Escherichia coli, GI1787247, Length=201, Percent_Identity=26.865671641791, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011251
- InterPro:   IPR016048
- InterPro:   IPR019946 [H]

Pfam domain/function: PF00296 Bac_luciferase [H]

EC number: =1.5.99.11 [H]

Molecular weight: Translated: 35746; Mature: 35615

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIRLGYQIPNFSYGTGVAELFPTVVKQVREAEASGFDTVFVMDHFYQLPMIGTPDQPML
CEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHCCCCCCCCCHHH
EAYTALGALASATSTIQLSTLVTGNTYRNPALLAKAVTTLDVVSGGRAILGIGAGWFELE
HHHHHHHHHHHCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCEEEH
HQQLGFEFGTFTDRFERLTEALEIIPPMLRGERPTFEGKYYRTESALNEPRLRPNIPIMI
HHHHCCCCCHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCEEECHHHCCCCCCCCCCCEEE
GGSGEKKTFGLAVKYADHLNLLSSLDEIPHKLTVLRQRCEEAGRDPSTLETSAFFSVFID
CCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCEEEEEEEE
DDSATAWKLAASQLSQNGIDLDTLPDEARAQVLGRTLVGNPEEIAEQVQTRVLDQGIDSV
CCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEE
TLNAPATGHLPGVVELIGNTLRPLFKN
EECCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TIRLGYQIPNFSYGTGVAELFPTVVKQVREAEASGFDTVFVMDHFYQLPMIGTPDQPML
EEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHCCCCCCCCCHHH
EAYTALGALASATSTIQLSTLVTGNTYRNPALLAKAVTTLDVVSGGRAILGIGAGWFELE
HHHHHHHHHHHCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCEEEH
HQQLGFEFGTFTDRFERLTEALEIIPPMLRGERPTFEGKYYRTESALNEPRLRPNIPIMI
HHHHCCCCCHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCEEECHHHCCCCCCCCCCCEEE
GGSGEKKTFGLAVKYADHLNLLSSLDEIPHKLTVLRQRCEEAGRDPSTLETSAFFSVFID
CCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCEEEEEEEE
DDSATAWKLAASQLSQNGIDLDTLPDEARAQVLGRTLVGNPEEIAEQVQTRVLDQGIDSV
CCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEE
TLNAPATGHLPGVVELIGNTLRPLFKN
EECCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]