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The map label for this gene is soxR [H]

Identifier: 169629395

GI number: 169629395

Start: 2361184

End: 2361636

Strand: Reverse

Name: soxR [H]

Synonym: MAB_2309c

Alternate gene names: 169629395

Gene position: 2361636-2361184 (Counterclockwise)

Preceding gene: 169629400

Following gene: 169629393

Centisome position: 46.61

GC content: 65.56

Gene sequence:

>453_bases
ATGAAGGGCAAGACCGAGCTGCTGCCGATCGGCGAGGTGGCCAGGCGTAGCGGAATCGCAGTGTCCGCCGTCCGCTACTA
CGCCGATATCGGACTGGTTCCGGCCGAACGCACCTCCGGGAACGTGCGGGTCTTCCGCCGCCACGCCCTACGGCGCATCT
CGTTGATCCGGGTGGCAACAGGGTTCGGTATCCCGCTATCGGAAGTCGCTGAGGTGCTGTCGACCCTGCCGGACTATCGC
GCCCCCAGCACCCGCGATTGGCAGCGCATCTCCCGCCGCTGGCACGCACACCTAGAAGCGCGCAAGAACGCCATCGCCGA
TATGCAGGAGAAGCTCACGGGATGCATCGGTTGCGGCTGCCTGTCGATGACGAAATGCGCCCTGTTCAACCCTGCGGACA
TCCTGGCCGACGACGGCTCGACCGGCGCACTGTTGCTTGCCGATCTCGGCTGA

Upstream 100 bases:

>100_bases
CCACCGGCGCCCAACTCGCGAACCATGCCGATACCGTATGAGCTAAAGTTCACTTGAGATCAACTCTGGGCGGCGAACAT
CTCTTCATAGAGGAGGCCTC

Downstream 100 bases:

>100_bases
CTACTTCAGGCCCGCGGCATCCATGCCGCGCAATTCCTTTTTGAGATCGGCGATCTCGTCGCGGAACCGGGCCGCCAACT
CAAACTGCAGATCGCGTGCC

Product: putative transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MKGKTELLPIGEVARRSGIAVSAVRYYADIGLVPAERTSGNVRVFRRHALRRISLIRVATGFGIPLSEVAEVLSTLPDYR
APSTRDWQRISRRWHAHLEARKNAIADMQEKLTGCIGCGCLSMTKCALFNPADILADDGSTGALLLADLG

Sequences:

>Translated_150_residues
MKGKTELLPIGEVARRSGIAVSAVRYYADIGLVPAERTSGNVRVFRRHALRRISLIRVATGFGIPLSEVAEVLSTLPDYR
APSTRDWQRISRRWHAHLEARKNAIADMQEKLTGCIGCGCLSMTKCALFNPADILADDGSTGALLLADLG
>Mature_150_residues
MKGKTELLPIGEVARRSGIAVSAVRYYADIGLVPAERTSGNVRVFRRHALRRISLIRVATGFGIPLSEVAEVLSTLPDYR
APSTRDWQRISRRWHAHLEARKNAIADMQEKLTGCIGCGCLSMTKCALFNPADILADDGSTGALLLADLG

Specific function: Activates the transcription of the soxS gene which itself controls the superoxide response regulon. SoxR contains a 2Fe-2S iron-sulfur cluster that may act as a redox sensor system that recognizes superoxide. The variable redox state of the Fe-S cluster i

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790498, Length=142, Percent_Identity=43.6619718309859, Blast_Score=131, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR010211
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 16333; Mature: 16333

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGKTELLPIGEVARRSGIAVSAVRYYADIGLVPAERTSGNVRVFRRHALRRISLIRVAT
CCCCCCCCCHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
GFGIPLSEVAEVLSTLPDYRAPSTRDWQRISRRWHAHLEARKNAIADMQEKLTGCIGCGC
CCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSMTKCALFNPADILADDGSTGALLLADLG
HHHHHHHCCCCHHHEECCCCCCEEEEEECC
>Mature Secondary Structure
MKGKTELLPIGEVARRSGIAVSAVRYYADIGLVPAERTSGNVRVFRRHALRRISLIRVAT
CCCCCCCCCHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHC
GFGIPLSEVAEVLSTLPDYRAPSTRDWQRISRRWHAHLEARKNAIADMQEKLTGCIGCGC
CCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSMTKCALFNPADILADDGSTGALLLADLG
HHHHHHHCCCCHHHEECCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9045804; 10984043 [H]