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The map label for this gene is napA [H]

Identifier: 169629371

GI number: 169629371

Start: 2333733

End: 2335052

Strand: Direct

Name: napA [H]

Synonym: MAB_2285

Alternate gene names: 169629371

Gene position: 2333733-2335052 (Clockwise)

Preceding gene: 169629370

Following gene: 169629372

Centisome position: 46.06

GC content: 64.24

Gene sequence:

>1320_bases
GTGAGTAACACAGCGGTGACCGCCGCGGCGGCCTTGTCCAAGGACGTATCCCTGATCTTCTTTGCAGACCTGGTCATCTT
GCTGGTGGCGGCCCTGGCGTGCGGTGCCGTCGCCGGCAAGATCGGACTACCCAAAATGGTCGGCGAGATCGCCGCAGGTG
TTCTCCTGGGCCCCACAGTGTTCGGCAGGTTGTTCCCCGAAACCAAAGATGCGCTGTTTCCCTCCGCCGGGACCGGCTCG
GAAATAATCTCCGGACTGTGCCTGCTGGCGGTGGTGTTGTTGGTCGGCGTCGCGGGCATGCACGTCGACGTCGATAAGCT
CAAACAACGGCTGGCCGGTATCGCCACGATCAGCGTGCTCGGGCTCGCCGTACCGCTGGCCGGGGGCATGGCCGTCGGAT
ATCTGGTTCCCGAGCCGTTGCGTCCGGCTGCCGTCGATCGCACCGTGTTCGCGTTGTTCTTGGGCACGGCGGTCGCGGTC
TCCGCGATACCGGTTATTGCCCGGATCCTGATGGACCTGGGCTTGGCATCGCACGAGATCGCTCAGGTGATCCTGGCCGC
CGCGATTGTCGATGATGTCGCCGGATGGCTGCTGCTGTCGGCAGTCACCGGCATGGCGTCCGACTCCGGAACTGGAGGCG
TTGCCGTGCTGAAAATGGCTGTCGCAGCCATCGTCGCGGTGGTCGCACTCACCGCACTTACCCGCCCTGCGCTACGAAAT
CGGTTGGCGCGCCGATGCTCTCGATGGAGTGCCCCAACATCCACCACCGTCACCGTGGCCACTATCATCGTGTGCGCCAC
CGCCGGACAACTGCTGGGTTTTGAACCCGTCATCGGAGCCTTCTTCGCGGGCATCCTGGTCATCGCGGCGACACCGGCCG
GAAGCCGAGTGCATAAACCGCTGCACGCCATGGCTGTTGCGTTCTTCGGACCGATCTTCTTCGCGACCATCGGGCTGCAA
CTGGACCTGGGAAGGCTGCTTTCCGGACCGGTGCTGGCGCTGACCGCCTCCATATGTGTGGTGGCGGTTTTCTCGAAATT
CCTGGGTGCGGGCATGGGCGCCAGAATCAGCGGATTCAGCTGGCCCGAGTCCGTAGCGGTGGGCGCAGGACTGAACACCC
GTGGCGTCATCCAGATCGTGATTGCCATGGTCGGGGTGCGATGCGGGGTGTTCAGCCCCGAGGTGTTCACCGCACTCGTC
GTCACCACCATCGCCACGACCGCGATTGCGGGCCCGGTCCTCAAACGCACACTGACACCCCGCCGACAGCTGCCGGCGGT
GATATCGAAACCCCCGCAAGAGCCCGCGCTCAACCGATAA

Upstream 100 bases:

>100_bases
AGTTCTACGGCGGTACCGTCAAATCCGGCGTCCGCGACGCGAACCACGCCATACGGGACATGGTGACCTCAAGAAACAGC
GACTGGAAGTAGCCCCGGTC

Downstream 100 bases:

>100_bases
ATGCCTGCAAAAAGGGAAGTGATAGCCGTGCCTGAGAAAACCGCCAACATCGGCGACCCTGTCGTCGCCATCGCCTCATA
TGCCGACCACCCCAGCGCCT

Product: Na+/H+ antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 438

Protein sequence:

>439_residues
MSNTAVTAAAALSKDVSLIFFADLVILLVAALACGAVAGKIGLPKMVGEIAAGVLLGPTVFGRLFPETKDALFPSAGTGS
EIISGLCLLAVVLLVGVAGMHVDVDKLKQRLAGIATISVLGLAVPLAGGMAVGYLVPEPLRPAAVDRTVFALFLGTAVAV
SAIPVIARILMDLGLASHEIAQVILAAAIVDDVAGWLLLSAVTGMASDSGTGGVAVLKMAVAAIVAVVALTALTRPALRN
RLARRCSRWSAPTSTTVTVATIIVCATAGQLLGFEPVIGAFFAGILVIAATPAGSRVHKPLHAMAVAFFGPIFFATIGLQ
LDLGRLLSGPVLALTASICVVAVFSKFLGAGMGARISGFSWPESVAVGAGLNTRGVIQIVIAMVGVRCGVFSPEVFTALV
VTTIATTAIAGPVLKRTLTPRRQLPAVISKPPQEPALNR

Sequences:

>Translated_439_residues
MSNTAVTAAAALSKDVSLIFFADLVILLVAALACGAVAGKIGLPKMVGEIAAGVLLGPTVFGRLFPETKDALFPSAGTGS
EIISGLCLLAVVLLVGVAGMHVDVDKLKQRLAGIATISVLGLAVPLAGGMAVGYLVPEPLRPAAVDRTVFALFLGTAVAV
SAIPVIARILMDLGLASHEIAQVILAAAIVDDVAGWLLLSAVTGMASDSGTGGVAVLKMAVAAIVAVVALTALTRPALRN
RLARRCSRWSAPTSTTVTVATIIVCATAGQLLGFEPVIGAFFAGILVIAATPAGSRVHKPLHAMAVAFFGPIFFATIGLQ
LDLGRLLSGPVLALTASICVVAVFSKFLGAGMGARISGFSWPESVAVGAGLNTRGVIQIVIAMVGVRCGVFSPEVFTALV
VTTIATTAIAGPVLKRTLTPRRQLPAVISKPPQEPALNR
>Mature_438_residues
SNTAVTAAAALSKDVSLIFFADLVILLVAALACGAVAGKIGLPKMVGEIAAGVLLGPTVFGRLFPETKDALFPSAGTGSE
IISGLCLLAVVLLVGVAGMHVDVDKLKQRLAGIATISVLGLAVPLAGGMAVGYLVPEPLRPAAVDRTVFALFLGTAVAVS
AIPVIARILMDLGLASHEIAQVILAAAIVDDVAGWLLLSAVTGMASDSGTGGVAVLKMAVAAIVAVVALTALTRPALRNR
LARRCSRWSAPTSTTVTVATIIVCATAGQLLGFEPVIGAFFAGILVIAATPAGSRVHKPLHAMAVAFFGPIFFATIGLQL
DLGRLLSGPVLALTASICVVAVFSKFLGAGMGARISGFSWPESVAVGAGLNTRGVIQIVIAMVGVRCGVFSPEVFTALVV
TTIATTAIAGPVLKRTLTPRRQLPAVISKPPQEPALNR

Specific function: This is a Na(+)/H(+) antiporter. It can mediate sodium uptake when a transmembrane pH gradient is applied [H]

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6322367, Length=422, Percent_Identity=28.1990521327014, Blast_Score=154, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 44496; Mature: 44365

Theoretical pI: Translated: 10.42; Mature: 10.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCHHHCCCCCCCCCCC
>Mature Secondary Structure 
SNTAVTAAAALSKDVSLIFFADLVILLVAALACGAVAGKIGLPKMVGEIAAGVLLGPTV
CCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH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HHHCCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1312090; 1325937 [H]