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The map label for this gene is ectB [H]

Identifier: 169629352

GI number: 169629352

Start: 2312626

End: 2313906

Strand: Reverse

Name: ectB [H]

Synonym: MAB_2266c

Alternate gene names: 169629352

Gene position: 2313906-2312626 (Counterclockwise)

Preceding gene: 169629353

Following gene: 169629351

Centisome position: 45.66

GC content: 62.22

Gene sequence:

>1281_bases
ATGACCGCCACCATGCCCGCGCAGGAAGCCGGGCTACCCAAGGTCATCAACGAGCGCGAATCCGAGGTTCGGAGTTATTG
CCGCACCTGGCCCACCACCTTCGCCTCCGCCTCCGGATCCTGGCTCACCGATACCAGCGGTGAGCGCTACCTAGATTTCT
TCGCCGGTGCCGGCGCACTCAACTACGGGCACAACAATCCGGTACTGAAGACCGCTCTCATCGACTACCTGACCACCGAT
GGCGTGGTGCATGGCCTGGACATGGCCACCGTCGCTAAGCAACAGTTCCTCGAGGAATTCGAACGGACCATCCTGCTGCC
CCGCGGCATGGACTACAAGGTGCAGTTCCCCGGCCCCACCGGGACCAATGCCGTCGAGTCCGCACTCAAGCTGGCGCGGA
ACATCACCGGGCGCGAGTCGATCATCAGCTTTACCAACGCATTCCACGGGATGACGCTGGGGTCGCTCGCGGTAACCGGC
AATTCGATGAAGCGTGCCGGTGCCGGAGTGCCGCTCGTGCATTCGACGCCCATGCCCTACGACAACTACTTCGGAGGCGT
TACCGAGGACTTTCAATGGTTCGAGAAGGTGCTTGACGATGAGGGCGGTGGCCTCAACAAGCCCGCCGCCGTCATCGTCG
AGACCGTACAAGGTGAGGGCGGTGTGAATGTGGCGCGCGCGGAATGGCTGCAGGCGCTCGCAGACCTGTGCCGCAAGCGC
GAGATCATTCTTATCGTCGATGACGTCCAGATGGGTTGCGGCCGAACGGGTTCATTCTTTTCGTTCGAGGAAGCCGGAAT
CAAACCCGATATCGTGACGTTGTCGAAGTCCATCAGCGGATATGGCCTGCCCATGGCCCTGACGCTCATCAGGCCAGATC
TGGACCAGTGGACTCCCGGCGAGCACAACGGGACGTTCCGCGGCAACAATCCGGCCTTCGTCACCGCGACCGCGACATTG
CAAAAGTACTGGCAGGACAACACGTTCAGCGATGACGTGCGACGCAAGGGCGACAGGCTGCATGACGAACTCACTGCGCT
GGTCGCCGACGACGACTCGGTGTCGATACGCGGCCGCGGCATGGTGCAGGGCATCGCCTTCGCCGACGCCGAACGAGGAC
CGCGGGTAAGCCGGGCAGCGTTCGAGCGCGGACTGCTGGTAGAGACCTCCGGCCCCAAGGACGAGGTCGTCAAGCTGCTA
CCGGCCCTGACCACCACCGATGAGCAACTCGATATCGGTATAGCCACCCTGCGTGAAGCAATCACCGAATCGGCTCAGTA
A

Upstream 100 bases:

>100_bases
GCACACGAGGCCGAGCCGCTACTTCGGCTCATTCCACTGAAACCACATCAAGCGCCCAGAGAAAGTGCCTAAAAACATTA
GGCCGAAAGGGGATACAGAA

Downstream 100 bases:

>100_bases
CTCCCACACAGCCCCCGGGCACTCAACGAGAGAAAGGAAGTATCTTGATCGTCCGTACTACCCAACAGATCACGGGTACC
GAGCGCGATGTCAGCGGTGA

Product: diaminobutyrate--2-oxoglutarate aminotransferase

Products: NA

Alternate protein names: DABA aminotransferase; Diaminobutyrate--2-oxoglutarate aminotransferase; L-2,4-diaminobutyric acid transaminase [H]

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MTATMPAQEAGLPKVINERESEVRSYCRTWPTTFASASGSWLTDTSGERYLDFFAGAGALNYGHNNPVLKTALIDYLTTD
GVVHGLDMATVAKQQFLEEFERTILLPRGMDYKVQFPGPTGTNAVESALKLARNITGRESIISFTNAFHGMTLGSLAVTG
NSMKRAGAGVPLVHSTPMPYDNYFGGVTEDFQWFEKVLDDEGGGLNKPAAVIVETVQGEGGVNVARAEWLQALADLCRKR
EIILIVDDVQMGCGRTGSFFSFEEAGIKPDIVTLSKSISGYGLPMALTLIRPDLDQWTPGEHNGTFRGNNPAFVTATATL
QKYWQDNTFSDDVRRKGDRLHDELTALVADDDSVSIRGRGMVQGIAFADAERGPRVSRAAFERGLLVETSGPKDEVVKLL
PALTTTDEQLDIGIATLREAITESAQ

Sequences:

>Translated_426_residues
MTATMPAQEAGLPKVINERESEVRSYCRTWPTTFASASGSWLTDTSGERYLDFFAGAGALNYGHNNPVLKTALIDYLTTD
GVVHGLDMATVAKQQFLEEFERTILLPRGMDYKVQFPGPTGTNAVESALKLARNITGRESIISFTNAFHGMTLGSLAVTG
NSMKRAGAGVPLVHSTPMPYDNYFGGVTEDFQWFEKVLDDEGGGLNKPAAVIVETVQGEGGVNVARAEWLQALADLCRKR
EIILIVDDVQMGCGRTGSFFSFEEAGIKPDIVTLSKSISGYGLPMALTLIRPDLDQWTPGEHNGTFRGNNPAFVTATATL
QKYWQDNTFSDDVRRKGDRLHDELTALVADDDSVSIRGRGMVQGIAFADAERGPRVSRAAFERGLLVETSGPKDEVVKLL
PALTTTDEQLDIGIATLREAITESAQ
>Mature_425_residues
TATMPAQEAGLPKVINERESEVRSYCRTWPTTFASASGSWLTDTSGERYLDFFAGAGALNYGHNNPVLKTALIDYLTTDG
VVHGLDMATVAKQQFLEEFERTILLPRGMDYKVQFPGPTGTNAVESALKLARNITGRESIISFTNAFHGMTLGSLAVTGN
SMKRAGAGVPLVHSTPMPYDNYFGGVTEDFQWFEKVLDDEGGGLNKPAAVIVETVQGEGGVNVARAEWLQALADLCRKRE
IILIVDDVQMGCGRTGSFFSFEEAGIKPDIVTLSKSISGYGLPMALTLIRPDLDQWTPGEHNGTFRGNNPAFVTATATLQ
KYWQDNTFSDDVRRKGDRLHDELTALVADDDSVSIRGRGMVQGIAFADAERGPRVSRAAFERGLLVETSGPKDEVVKLLP
ALTTTDEQLDIGIATLREAITESAQ

Specific function: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate [H]

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=422, Percent_Identity=26.5402843601896, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI37574042, Length=446, Percent_Identity=27.1300448430493, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI13994255, Length=435, Percent_Identity=25.7471264367816, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI226442705, Length=445, Percent_Identity=26.9662921348315, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI284507298, Length=313, Percent_Identity=26.8370607028754, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI226442709, Length=398, Percent_Identity=27.8894472361809, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI24119277, Length=435, Percent_Identity=24.8275862068966, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI1789016, Length=425, Percent_Identity=30.3529411764706, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1787560, Length=405, Percent_Identity=31.358024691358, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI145693181, Length=394, Percent_Identity=30.4568527918782, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1789759, Length=395, Percent_Identity=30.126582278481, Blast_Score=148, Evalue=8e-37,
Organism=Escherichia coli, GI1788044, Length=391, Percent_Identity=28.9002557544757, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1786991, Length=410, Percent_Identity=25.1219512195122, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI1786349, Length=355, Percent_Identity=27.3239436619718, Blast_Score=88, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI25144271, Length=421, Percent_Identity=27.3159144893112, Blast_Score=148, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI32564660, Length=420, Percent_Identity=26.9047619047619, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI25144274, Length=292, Percent_Identity=27.7397260273973, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71992977, Length=449, Percent_Identity=24.7216035634744, Blast_Score=91, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6323470, Length=416, Percent_Identity=31.4903846153846, Blast_Score=162, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6324432, Length=419, Percent_Identity=29.8329355608592, Blast_Score=156, Evalue=5e-39,
Organism=Saccharomyces cerevisiae, GI6321456, Length=433, Percent_Identity=25.635103926097, Blast_Score=98, Evalue=3e-21,
Organism=Drosophila melanogaster, GI21357415, Length=403, Percent_Identity=27.7915632754342, Blast_Score=134, Evalue=9e-32,
Organism=Drosophila melanogaster, GI21356575, Length=430, Percent_Identity=27.2093023255814, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI161085790, Length=428, Percent_Identity=26.1682242990654, Blast_Score=114, Evalue=9e-26,
Organism=Drosophila melanogaster, GI28574759, Length=431, Percent_Identity=25.9860788863109, Blast_Score=112, Evalue=6e-25,
Organism=Drosophila melanogaster, GI281366494, Length=432, Percent_Identity=24.0740740740741, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24667139, Length=432, Percent_Identity=24.0740740740741, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24667143, Length=432, Percent_Identity=24.0740740740741, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR004637
- InterPro:   IPR012773
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.76 [H]

Molecular weight: Translated: 46268; Mature: 46136

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS00599 AA_TRANSFER_CLASS_2 ; PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTATMPAQEAGLPKVINERESEVRSYCRTWPTTFASASGSWLTDTSGERYLDFFAGAGAL
CCCCCCCHHCCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCEEECCCCCHHHHHHHCCCEE
NYGHNNPVLKTALIDYLTTDGVVHGLDMATVAKQQFLEEFERTILLPRGMDYKVQFPGPT
ECCCCCCHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHEECCCCCCEEEECCCCC
GTNAVESALKLARNITGRESIISFTNAFHGMTLGSLAVTGNSMKRAGAGVPLVHSTPMPY
CCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEECCEEECCCCHHHCCCCCCEEECCCCCC
DNYFGGVTEDFQWFEKVLDDEGGGLNKPAAVIVETVQGEGGVNVARAEWLQALADLCRKR
HHHCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCC
EIILIVDDVQMGCGRTGSFFSFEEAGIKPDIVTLSKSISGYGLPMALTLIRPDLDQWTPG
CEEEEEECCCCCCCCCCCCCCHHHCCCCCCEEEHHCCCCCCCCCEEEEEECCCCCCCCCC
EHNGTFRGNNPAFVTATATLQKYWQDNTFSDDVRRKGDRLHDELTALVADDDSVSIRGRG
CCCCCCCCCCCEEEEEHHHHHHHHCCCCCCHHHHHHHHHHHHHHHEEEECCCCEEEECCC
MVQGIAFADAERGPRVSRAAFERGLLVETSGPKDEVVKLLPALTTTDEQLDIGIATLREA
CEEEEEECCCCCCCCHHHHHHHCCEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHH
ITESAQ
HHHCCC
>Mature Secondary Structure 
TATMPAQEAGLPKVINERESEVRSYCRTWPTTFASASGSWLTDTSGERYLDFFAGAGAL
CCCCCCHHCCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCEEECCCCCHHHHHHHCCCEE
NYGHNNPVLKTALIDYLTTDGVVHGLDMATVAKQQFLEEFERTILLPRGMDYKVQFPGPT
ECCCCCCHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHEECCCCCCEEEECCCCC
GTNAVESALKLARNITGRESIISFTNAFHGMTLGSLAVTGNSMKRAGAGVPLVHSTPMPY
CCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEECCEEECCCCHHHCCCCCCEEECCCCCC
DNYFGGVTEDFQWFEKVLDDEGGGLNKPAAVIVETVQGEGGVNVARAEWLQALADLCRKR
HHHCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCC
EIILIVDDVQMGCGRTGSFFSFEEAGIKPDIVTLSKSISGYGLPMALTLIRPDLDQWTPG
CEEEEEECCCCCCCCCCCCCCHHHCCCCCCEEEHHCCCCCCCCCEEEEEECCCCCCCCCC
EHNGTFRGNNPAFVTATATLQKYWQDNTFSDDVRRKGDRLHDELTALVADDDSVSIRGRG
CCCCCCCCCCCEEEEEHHHHHHHHCCCCCCHHHHHHHHHHHHHHHEEEECCCCEEEECCC
MVQGIAFADAERGPRVSRAAFERGLLVETSGPKDEVVKLLPALTTTDEQLDIGIATLREA
CEEEEEECCCCCCCCHHHHHHHCCEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHH
ITESAQ
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA