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The map label for this gene is ppe4 [H]

Identifier: 169629316

GI number: 169629316

Start: 2251963

End: 2253534

Strand: Reverse

Name: ppe4 [H]

Synonym: MAB_2230c

Alternate gene names: 169629316

Gene position: 2253534-2251963 (Counterclockwise)

Preceding gene: 169629317

Following gene: 169629315

Centisome position: 44.47

GC content: 67.81

Gene sequence:

>1572_bases
GTGTCGGCTCCGATTTGGATGGCTTCTCCCCCCGAGGTCCACTCGGCGCTGCTGAGCGCCGGACCCGGGCCGGGCGCACT
GCTGGCCGCTGCCGCGCAATGGCAGGCGCTCTCGGTGCAATACACCACTGCCGCAACGGAGCTGACACAACTGCTTGCCG
CCACCGGCTCCGGGTCCTGGCAGGGACCCAGCGCGGCACAATACGTTGCCAGTCACGCCCCTTACCTGGCCTGGCTGACC
CAGCAGAGTGCGATGAGCGCCACCAACGCCGTGCTGCACGAAACCAGCGCCGCTGCCTACACCACCGCCCTGGCGGCCAT
GCCCACCCTGGCCGAGCTGGCCGCCAACCACATGATCCACGGAGTGCTGCTGGCCACCAACTTCTTTGGTATCAACACCA
TTCCCATCGCGCTGAACGAGGCCGACTACATCCGGATGTGGATTCAGGCCGCCACCACCATGGGCGTCTACCAAGGTGTC
TCGACTGCCGCCGTCACATCGGTGGCGCCCACGCCGCCCGCCCCGACGATCATGGCACCCGGCGGCGAAATGTCCCGCAT
GTCGGCCGATATGTCGGGCATGGCCGCCCAGGCACAGGCCGCCGAATCCGGTATGGCGCTAGACGACAGCGAGAGCTTCT
TCGACAAGCTCATGCGGCAGATCCAGGAATTCTTCAGCGACCCACTGGGCACCCTGCAGAAGATCTTGCAGGACTTCATG
CGTAATCCGCTTGAGGCGCTGGTGGCCTGGGGCCCGTTGCTGTTCTTCATCGCATACGAGGCGTTCTTCATTCCCTTCGG
GTTCACCTTCTGGGGCGTCATGTTGTCGGCCCCACTGTGGCTGCCGCTACTCTTGGTGGGCTTGGCCCAGTTGGTTAATC
CGGTTCCAGTCGAGGCCGATGCACCCGCCGACGAACCCGCGCCGCAACAGGCGCGAGTGGAACGTAGTTCACCTCAGCAG
CAGCCATTTGCGATGGGCGGAATGCCCGGTGGCGGTGGCGCACCGGCCACACCTGCCAACGCACCGGCGACACCGGCCAA
CGCACCCGCTTCGCCGGCCGCGGCGGCCGCCACACCGGCTTACATGGTGTACGCGGTGCAGGAGGATCCACCGGCGGCAA
GGTTTGGGCCGACGCTCAATGAGGGCAGCGGCGCCAAGGCGCCGGCGGCCGGAATCTCTGCCGCCGCCGCGGCTGCCGCC
TCGGCACGCTCACGCGCGCGCCGCAAGCGCGGCGCCCGGATCAAAGATCCTGCACCGCAGTTCATGGACATGAACTCGCC
GGTGGACCCGGACTTTTCGGAGCCGGCGACCCGGCACACCGCCGGAGTCGGGGCCTCGGGCCGCGGGGCTGGACAGCTTG
GCTTCGCCGGCACGCTCCCCCGGACCACATCGACGACAAGCGCGGCCGGTTTGATCGAACGCGAGGCCGCCTCGGAGATG
GACGGAACTCGCACCGTGCCGATGCTTCCTACCAGCTGGGGCACCGACCCCGAGCCAGACCCCGATAGAGCCCCTTCCGT
GCCAGCACCGGATGAGGACTGGCCGCCCGGGGAAAGGGGGGCGAGCACCTGA

Upstream 100 bases:

>100_bases
TGGGCCGGGCCGGACTCGGTGTGTCGGAGTCCGCGGCCAGCTACACCACCGGGGACATGCAGGCCGCCGCGGCGTACATG
ATCGCGCGGGGTTAACACCG

Downstream 100 bases:

>100_bases
TCCGCCACAGAAGTACGACGCAATACACGACGAAGTAACAGAGAATAAGGAGAGCATCTTATGAGTTTGCTTGACGCACA
CATTCCCGCTCTGGTGGCCG

Product: PPE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 523; Mature: 522

Protein sequence:

>523_residues
MSAPIWMASPPEVHSALLSAGPGPGALLAAAAQWQALSVQYTTAATELTQLLAATGSGSWQGPSAAQYVASHAPYLAWLT
QQSAMSATNAVLHETSAAAYTTALAAMPTLAELAANHMIHGVLLATNFFGINTIPIALNEADYIRMWIQAATTMGVYQGV
STAAVTSVAPTPPAPTIMAPGGEMSRMSADMSGMAAQAQAAESGMALDDSESFFDKLMRQIQEFFSDPLGTLQKILQDFM
RNPLEALVAWGPLLFFIAYEAFFIPFGFTFWGVMLSAPLWLPLLLVGLAQLVNPVPVEADAPADEPAPQQARVERSSPQQ
QPFAMGGMPGGGGAPATPANAPATPANAPASPAAAAATPAYMVYAVQEDPPAARFGPTLNEGSGAKAPAAGISAAAAAAA
SARSRARRKRGARIKDPAPQFMDMNSPVDPDFSEPATRHTAGVGASGRGAGQLGFAGTLPRTTSTTSAAGLIEREAASEM
DGTRTVPMLPTSWGTDPEPDPDRAPSVPAPDEDWPPGERGAST

Sequences:

>Translated_523_residues
MSAPIWMASPPEVHSALLSAGPGPGALLAAAAQWQALSVQYTTAATELTQLLAATGSGSWQGPSAAQYVASHAPYLAWLT
QQSAMSATNAVLHETSAAAYTTALAAMPTLAELAANHMIHGVLLATNFFGINTIPIALNEADYIRMWIQAATTMGVYQGV
STAAVTSVAPTPPAPTIMAPGGEMSRMSADMSGMAAQAQAAESGMALDDSESFFDKLMRQIQEFFSDPLGTLQKILQDFM
RNPLEALVAWGPLLFFIAYEAFFIPFGFTFWGVMLSAPLWLPLLLVGLAQLVNPVPVEADAPADEPAPQQARVERSSPQQ
QPFAMGGMPGGGGAPATPANAPATPANAPASPAAAAATPAYMVYAVQEDPPAARFGPTLNEGSGAKAPAAGISAAAAAAA
SARSRARRKRGARIKDPAPQFMDMNSPVDPDFSEPATRHTAGVGASGRGAGQLGFAGTLPRTTSTTSAAGLIEREAASEM
DGTRTVPMLPTSWGTDPEPDPDRAPSVPAPDEDWPPGERGAST
>Mature_522_residues
SAPIWMASPPEVHSALLSAGPGPGALLAAAAQWQALSVQYTTAATELTQLLAATGSGSWQGPSAAQYVASHAPYLAWLTQ
QSAMSATNAVLHETSAAAYTTALAAMPTLAELAANHMIHGVLLATNFFGINTIPIALNEADYIRMWIQAATTMGVYQGVS
TAAVTSVAPTPPAPTIMAPGGEMSRMSADMSGMAAQAQAAESGMALDDSESFFDKLMRQIQEFFSDPLGTLQKILQDFMR
NPLEALVAWGPLLFFIAYEAFFIPFGFTFWGVMLSAPLWLPLLLVGLAQLVNPVPVEADAPADEPAPQQARVERSSPQQQ
PFAMGGMPGGGGAPATPANAPATPANAPASPAAAAATPAYMVYAVQEDPPAARFGPTLNEGSGAKAPAAGISAAAAAAAS
ARSRARRKRGARIKDPAPQFMDMNSPVDPDFSEPATRHTAGVGASGRGAGQLGFAGTLPRTTSTTSAAGLIEREAASEMD
GTRTVPMLPTSWGTDPEPDPDRAPSVPAPDEDWPPGERGAST

Specific function: Unknown

COG id: COG5651

COG function: function code N; PPE-repeat proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial PPE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000030 [H]

Pfam domain/function: PF00823 PPE [H]

EC number: NA

Molecular weight: Translated: 53951; Mature: 53820

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPIWMASPPEVHSALLSAGPGPGALLAAAAQWQALSVQYTTAATELTQLLAATGSGSW
CCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHEEEEEEEHHHHHHHHHHHHHCCCCCC
QGPSAAQYVASHAPYLAWLTQQSAMSATNAVLHETSAAAYTTALAAMPTLAELAANHMIH
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVLLATNFFGINTIPIALNEADYIRMWIQAATTMGVYQGVSTAAVTSVAPTPPAPTIMAP
HHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCEEECC
GGEMSRMSADMSGMAAQAQAAESGMALDDSESFFDKLMRQIQEFFSDPLGTLQKILQDFM
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
RNPLEALVAWGPLLFFIAYEAFFIPFGFTFWGVMLSAPLWLPLLLVGLAQLVNPVPVEAD
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
APADEPAPQQARVERSSPQQQPFAMGGMPGGGGAPATPANAPATPANAPASPAAAAATPA
CCCCCCCCHHHHHHHCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCE
YMVYAVQEDPPAARFGPTLNEGSGAKAPAAGISAAAAAAASARSRARRKRGARIKDPAPQ
EEEEEECCCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
FMDMNSPVDPDFSEPATRHTAGVGASGRGAGQLGFAGTLPRTTSTTSAAGLIEREAASEM
HHCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
DGTRTVPMLPTSWGTDPEPDPDRAPSVPAPDEDWPPGERGAST
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SAPIWMASPPEVHSALLSAGPGPGALLAAAAQWQALSVQYTTAATELTQLLAATGSGSW
CCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHEEEEEEEHHHHHHHHHHHHHCCCCCC
QGPSAAQYVASHAPYLAWLTQQSAMSATNAVLHETSAAAYTTALAAMPTLAELAANHMIH
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVLLATNFFGINTIPIALNEADYIRMWIQAATTMGVYQGVSTAAVTSVAPTPPAPTIMAP
HHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCEEECC
GGEMSRMSADMSGMAAQAQAAESGMALDDSESFFDKLMRQIQEFFSDPLGTLQKILQDFM
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
RNPLEALVAWGPLLFFIAYEAFFIPFGFTFWGVMLSAPLWLPLLLVGLAQLVNPVPVEAD
HCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
APADEPAPQQARVERSSPQQQPFAMGGMPGGGGAPATPANAPATPANAPASPAAAAATPA
CCCCCCCCHHHHHHHCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCE
YMVYAVQEDPPAARFGPTLNEGSGAKAPAAGISAAAAAAASARSRARRKRGARIKDPAPQ
EEEEEECCCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHH
FMDMNSPVDPDFSEPATRHTAGVGASGRGAGQLGFAGTLPRTTSTTSAAGLIEREAASEM
HHCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
DGTRTVPMLPTSWGTDPEPDPDRAPSVPAPDEDWPPGERGAST
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]