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The map label for this gene is mbtB [H]

Identifier: 169629210

GI number: 169629210

Start: 2131531

End: 2134998

Strand: Direct

Name: mbtB [H]

Synonym: MAB_2124

Alternate gene names: 169629210

Gene position: 2131531-2134998 (Clockwise)

Preceding gene: 169629209

Following gene: 169629212

Centisome position: 42.07

GC content: 64.88

Gene sequence:

>3468_bases
ATGGAAGCAATCAGTAGGGACGAGATCAAGCTGACGGTCGCCGACCTCATCGGGCTTACAGCCCAGGATATTTCGGATGG
CGATGACCTCATCACACTCGGATTGGACTCGATCCGCATGATGACTCTGGCCGGTGGATGGCGCAAACGGGGCAGCCGTG
TCACCTTCGCTCAGCTGGCGGCCGAGCCTTCGGTGGACTCCTGGTACGCGCTGCTGCGGGCGGATGACGAGGTGGCCCCG
GATGAGGAGGCCGCGGCGGACGAAACAGATGGTCAAGACGGCGAGGACGCGCCTTTCCCGCTGGCCACCATGCAACACGC
GTACTGGATCGGCCGATCGGAGGATCAGGAGCTCGGTGGGGTAGCGGCACACCTGTACGTCGAATTCGACGGAGGAGCAA
TCGATCCCGACCGACTCAAGGCTGCGGTAGAGCGCTTGGTGGCCGCCCATCCGATGTTACGCACCAAGTTTCTGCCCGAC
GGCACACAGCAGACCATGGCGGCTCCCGGCCGTGACGTGTTCACCGTGGTGGATCTGCGCGGACGTGCGGCCGGCGAAGT
TGACGCGGCACTTGCCGAACTGCGGGAGCATAAGACGCATCAGCGCCTGGCCATAGAGGACGGGCAGGTGCTCGACGTCA
CGCTGACCTTGCGTGATGACAACAACAGCAGATTGCATCTCGACGTCGACATGCTTGCCGGCGACGCGATGAGCTACCGG
GTCTTGATATCTGATTTGGCGGCGCTCTATCACGGTGGCGCGCAACCTGAATTGGGATATTCCTACCGGCGGTACCGCAC
CGAGGATCGTGGCGATGCGGCCGCGCACGAGCGTGACAGGCAATGGTGGCAGGACAGGCTGGCGGACCTGCCGGGTGCTC
CGGAACTGCCGGTTGTCCCGGTGAGCGAACGCACCGATCAGCACCGCACCGTCCGGTACAACTACTGGCTTGAACCTGAG
GCCAAGCAACAGCTGCTGGTCGCCGCCCACCAGCGCGGCATCACCCCCGCCATGGCGATGGCCGCTGTCTTCGCCGAAAC
CATCGGCGGATGGTCGGCGCAGAGCCGATTCTTGTTGAATGTCCCCCTATTTCATCGCGAGTCGGTGCATCCTGACATAG
ATCGGGTGATCGGTGACTTCACCTCCTCGATCATGCTCGACGTCGACCTGACCGAGGACATGTCGGTGGCCGACCGGGCC
CGTGCGTTGCAGCGCACCATGTATGAGAGCGGGGCGCACTCGGCGTACCCGGGATTGAATGTGCTGCGCGACCTGGGTAG
GCACCGGGGCGAACCGGTGCTGGCACCGATCGTGTACACCAGCGCGCTAAATCTGGGGGAACTGTTCGCCGAGCCGGTCA
TGCAGACCTTCGGGGAACCGGTATGGATCATCTCGCAGGGACCGCAGGTGCTACTGGACGCTCAGGTCACCGAGGTGCGG
GGAGGCTTGCTGTTGAACTGGGACGTTCGCGAATCAGCGTTCCCGCACGGCATGGTGGCCGCGATGTTCGAGCGGTACAC
CGATGCGGTGGCCGCCTTGTGCACGGGAGCGGACGGCTGGAACAGCGATGCGGCTGTGCGACTGCCTGCTTCCCAGGAAC
GGGTGCGGCGCGCCGTCAACGCGACGGCTGGCCCGGTAACCGGCCGGCGACTGCATGAAGGCTTCTTCGACTTCGCCCAG
TCGAACCCCGGGATGCCCGCGGTGGTCTGGGGTTTTGGCGACGAGGATGGTGTGTGGTCCTACCGCGATGTGGCGGCCCA
GGCCCTGGCGGTGGCGGGCGCCTTGCGGGAGCGGGGGGTACGCCCGGGTGATTGTGTTGCCGTGCAGTTGCCCAAGGGGC
GCGACCAGATTCCCGCGGTGCTCGGTGTGCTGGCGGCCGGCGCCACGTATGTACCGATCGGATTCGATCAGCCGGCCCAG
CGCCGCGCGGCGATCCTTGAAACCGGCGGAATCTCCGTGGCGTTGACCACCGCTGACTCCGATATGCCGATTGATCATCT
GTCGATTGACGCGGCCCGTCAATATCCGGAACCGCTCCGGGAGCCGGTGCTGCCGGATGCTTCGCAGATCGCATACGTCC
TTTTCACATCGGGCTCTACCGGAACCCCGAAGGGTGTCGATGTCTCACATGCGGCCGCTATGAACACGATTGACGCCTTG
AACGATGAGTTCGAAGTGGTCACCTCGGATCGTGCGCTCGGACTGTCGGCCCTCGAGTTCGATCTGTCCGTATACGACAT
CTTCGGCATGTTCTCTGTCGGCGCCGCCGTGGTTGCGGTGGACGCCGCGCAGCGGGCCGAGGCCACCACATGGGTGGAAT
TGATACGGCGACATAGGGTTTCGATTATCAACTGTGTGCCGGGACTGCTCGACATGATTCTGGCAATGGGCGGGGGTGAG
CTGGGCGATTCCCTGCGCGCGGTCATCCTGGGAGGTGACTGGGTAAGTTCGGATCTGGCGCGCAGGCTCGCCGCGCAAGT
CCCGGGCTGTCGCTTCACCGGCCTGGGTGGGGCGACCGAGGCCGCCATACACAGCACGATTTGTGAGGTGCTGGGTGACC
CGCCGCAGCACTGGGCCACAATTCCTTTCGGTGTGCCGCTGCGCAACGTACGGTGCCGTGTCGTTTCGCAGGCAGGTCGT
GACTGTCTGGACTGGGTGCCCGGCGAACTGTGGATCGGTGGCGACAGCGTCGCGTCCGGTTACCGCAATGACCCGGAGCG
CACGGCAGAGCGTTTCGTCGAGCACGACGGTCTACGTTGGTACCGGACGGGCGATATGGCGCGCTACTGGCCCGATGGCA
CCATCGAATTCCTGGGCCGCGCCGACCATCAGGTGAAGATCCGCGGGTACCGCGTGGAACTGGGCGAAGTCGAGAGCGCG
CTGCGCTTGATACCGGGCATACGGCACGCGGTCGCCGCCGTCGTGGGGGCGGATGCTCCGAATCTTGTTGCCGCGGTGGC
GGGTACGCCCGACCCGGCGGCCGACTATGCGGCGCTGCTCGGCGACTTACTGCCCGGCTACATGATTCCCGCCCGGATCG
AGCTTCTTGAGCAGATGCCACTGACGTCGAACGGCAAGATGGATCGACGTGCGGTGACTGCGCTCCTGGAGCAAGTGGCT
GTTGGGGGTGCCGATGCGGGGCCGCGGCACGACCTCGATGCGGCTCTTGTCGATCTGGTTTCCGGTGTACTTGGCATCGA
ATCGATGGGCGTACATGACGATTTCTTCGCTCGCGGTGGCGATTCGGTGTTGGCGACCGCTGTGATCGCCCGAGTACGAG
ACTGGCTGTCGGTCGACCACGCGCTCGTCGGGGACTTCTTCGCCACCCGCACCGTCGCGGGGCTGGCCGACAGGTTGTTG
CAGCGTGAAGCCGACCGCGGTACGCCGGACCGGCTGGCCGTCGTCGCGGGCCACTATCTCGAGATCGCGGCGATGACCGA
CGAGGAGGTCTTGGCCGGGACCGTCTGA

Upstream 100 bases:

>100_bases
TGTTCACCCCGGCGGATGCCAGCCGGCTGGCGCAGTTGTGGCAGCGCAGCGTGGCCGCACTGGCCGGGGCACTCGACGGA
TAGCGACGGGAAGAATACGG

Downstream 100 bases:

>100_bases
TAGGTCAGGAGGCAGCGGGTGTGCCGAGCACCATGCTGCCCACGCTGCACTCCTGTAGCTCGGGCACGGCGGCGGCCGCG
GTGAATGCCGCGGTATCGCC

Product: putative phenyloxazoline synthase MbtB

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: Mycobactin synthetase protein B [H]

Number of amino acids: Translated: 1155; Mature: 1155

Protein sequence:

>1155_residues
MEAISRDEIKLTVADLIGLTAQDISDGDDLITLGLDSIRMMTLAGGWRKRGSRVTFAQLAAEPSVDSWYALLRADDEVAP
DEEAAADETDGQDGEDAPFPLATMQHAYWIGRSEDQELGGVAAHLYVEFDGGAIDPDRLKAAVERLVAAHPMLRTKFLPD
GTQQTMAAPGRDVFTVVDLRGRAAGEVDAALAELREHKTHQRLAIEDGQVLDVTLTLRDDNNSRLHLDVDMLAGDAMSYR
VLISDLAALYHGGAQPELGYSYRRYRTEDRGDAAAHERDRQWWQDRLADLPGAPELPVVPVSERTDQHRTVRYNYWLEPE
AKQQLLVAAHQRGITPAMAMAAVFAETIGGWSAQSRFLLNVPLFHRESVHPDIDRVIGDFTSSIMLDVDLTEDMSVADRA
RALQRTMYESGAHSAYPGLNVLRDLGRHRGEPVLAPIVYTSALNLGELFAEPVMQTFGEPVWIISQGPQVLLDAQVTEVR
GGLLLNWDVRESAFPHGMVAAMFERYTDAVAALCTGADGWNSDAAVRLPASQERVRRAVNATAGPVTGRRLHEGFFDFAQ
SNPGMPAVVWGFGDEDGVWSYRDVAAQALAVAGALRERGVRPGDCVAVQLPKGRDQIPAVLGVLAAGATYVPIGFDQPAQ
RRAAILETGGISVALTTADSDMPIDHLSIDAARQYPEPLREPVLPDASQIAYVLFTSGSTGTPKGVDVSHAAAMNTIDAL
NDEFEVVTSDRALGLSALEFDLSVYDIFGMFSVGAAVVAVDAAQRAEATTWVELIRRHRVSIINCVPGLLDMILAMGGGE
LGDSLRAVILGGDWVSSDLARRLAAQVPGCRFTGLGGATEAAIHSTICEVLGDPPQHWATIPFGVPLRNVRCRVVSQAGR
DCLDWVPGELWIGGDSVASGYRNDPERTAERFVEHDGLRWYRTGDMARYWPDGTIEFLGRADHQVKIRGYRVELGEVESA
LRLIPGIRHAVAAVVGADAPNLVAAVAGTPDPAADYAALLGDLLPGYMIPARIELLEQMPLTSNGKMDRRAVTALLEQVA
VGGADAGPRHDLDAALVDLVSGVLGIESMGVHDDFFARGGDSVLATAVIARVRDWLSVDHALVGDFFATRTVAGLADRLL
QREADRGTPDRLAVVAGHYLEIAAMTDEEVLAGTV

Sequences:

>Translated_1155_residues
MEAISRDEIKLTVADLIGLTAQDISDGDDLITLGLDSIRMMTLAGGWRKRGSRVTFAQLAAEPSVDSWYALLRADDEVAP
DEEAAADETDGQDGEDAPFPLATMQHAYWIGRSEDQELGGVAAHLYVEFDGGAIDPDRLKAAVERLVAAHPMLRTKFLPD
GTQQTMAAPGRDVFTVVDLRGRAAGEVDAALAELREHKTHQRLAIEDGQVLDVTLTLRDDNNSRLHLDVDMLAGDAMSYR
VLISDLAALYHGGAQPELGYSYRRYRTEDRGDAAAHERDRQWWQDRLADLPGAPELPVVPVSERTDQHRTVRYNYWLEPE
AKQQLLVAAHQRGITPAMAMAAVFAETIGGWSAQSRFLLNVPLFHRESVHPDIDRVIGDFTSSIMLDVDLTEDMSVADRA
RALQRTMYESGAHSAYPGLNVLRDLGRHRGEPVLAPIVYTSALNLGELFAEPVMQTFGEPVWIISQGPQVLLDAQVTEVR
GGLLLNWDVRESAFPHGMVAAMFERYTDAVAALCTGADGWNSDAAVRLPASQERVRRAVNATAGPVTGRRLHEGFFDFAQ
SNPGMPAVVWGFGDEDGVWSYRDVAAQALAVAGALRERGVRPGDCVAVQLPKGRDQIPAVLGVLAAGATYVPIGFDQPAQ
RRAAILETGGISVALTTADSDMPIDHLSIDAARQYPEPLREPVLPDASQIAYVLFTSGSTGTPKGVDVSHAAAMNTIDAL
NDEFEVVTSDRALGLSALEFDLSVYDIFGMFSVGAAVVAVDAAQRAEATTWVELIRRHRVSIINCVPGLLDMILAMGGGE
LGDSLRAVILGGDWVSSDLARRLAAQVPGCRFTGLGGATEAAIHSTICEVLGDPPQHWATIPFGVPLRNVRCRVVSQAGR
DCLDWVPGELWIGGDSVASGYRNDPERTAERFVEHDGLRWYRTGDMARYWPDGTIEFLGRADHQVKIRGYRVELGEVESA
LRLIPGIRHAVAAVVGADAPNLVAAVAGTPDPAADYAALLGDLLPGYMIPARIELLEQMPLTSNGKMDRRAVTALLEQVA
VGGADAGPRHDLDAALVDLVSGVLGIESMGVHDDFFARGGDSVLATAVIARVRDWLSVDHALVGDFFATRTVAGLADRLL
QREADRGTPDRLAVVAGHYLEIAAMTDEEVLAGTV
>Mature_1155_residues
MEAISRDEIKLTVADLIGLTAQDISDGDDLITLGLDSIRMMTLAGGWRKRGSRVTFAQLAAEPSVDSWYALLRADDEVAP
DEEAAADETDGQDGEDAPFPLATMQHAYWIGRSEDQELGGVAAHLYVEFDGGAIDPDRLKAAVERLVAAHPMLRTKFLPD
GTQQTMAAPGRDVFTVVDLRGRAAGEVDAALAELREHKTHQRLAIEDGQVLDVTLTLRDDNNSRLHLDVDMLAGDAMSYR
VLISDLAALYHGGAQPELGYSYRRYRTEDRGDAAAHERDRQWWQDRLADLPGAPELPVVPVSERTDQHRTVRYNYWLEPE
AKQQLLVAAHQRGITPAMAMAAVFAETIGGWSAQSRFLLNVPLFHRESVHPDIDRVIGDFTSSIMLDVDLTEDMSVADRA
RALQRTMYESGAHSAYPGLNVLRDLGRHRGEPVLAPIVYTSALNLGELFAEPVMQTFGEPVWIISQGPQVLLDAQVTEVR
GGLLLNWDVRESAFPHGMVAAMFERYTDAVAALCTGADGWNSDAAVRLPASQERVRRAVNATAGPVTGRRLHEGFFDFAQ
SNPGMPAVVWGFGDEDGVWSYRDVAAQALAVAGALRERGVRPGDCVAVQLPKGRDQIPAVLGVLAAGATYVPIGFDQPAQ
RRAAILETGGISVALTTADSDMPIDHLSIDAARQYPEPLREPVLPDASQIAYVLFTSGSTGTPKGVDVSHAAAMNTIDAL
NDEFEVVTSDRALGLSALEFDLSVYDIFGMFSVGAAVVAVDAAQRAEATTWVELIRRHRVSIINCVPGLLDMILAMGGGE
LGDSLRAVILGGDWVSSDLARRLAAQVPGCRFTGLGGATEAAIHSTICEVLGDPPQHWATIPFGVPLRNVRCRVVSQAGR
DCLDWVPGELWIGGDSVASGYRNDPERTAERFVEHDGLRWYRTGDMARYWPDGTIEFLGRADHQVKIRGYRVELGEVESA
LRLIPGIRHAVAAVVGADAPNLVAAVAGTPDPAADYAALLGDLLPGYMIPARIELLEQMPLTSNGKMDRRAVTALLEQVA
VGGADAGPRHDLDAALVDLVSGVLGIESMGVHDDFFARGGDSVLATAVIARVRDWLSVDHALVGDFFATRTVAGLADRLL
QREADRGTPDRLAVVAGHYLEIAAMTDEEVLAGTV

Specific function: Involved in the initial steps of the mycobactin biosynthetic pathway. Putatively couples activated salicylic acid with serine or threonine and cyclizes this precursor to the hydroxyphenyloxazoline ring system present in this class of siderophores [H]

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=462, Percent_Identity=24.4588744588745, Blast_Score=91, Evalue=9e-18,
Organism=Homo sapiens, GI4758332, Length=193, Percent_Identity=31.6062176165803, Blast_Score=76, Evalue=2e-13,
Organism=Homo sapiens, GI12669909, Length=193, Percent_Identity=31.6062176165803, Blast_Score=76, Evalue=2e-13,
Organism=Homo sapiens, GI42794754, Length=198, Percent_Identity=32.8282828282828, Blast_Score=71, Evalue=6e-12,
Organism=Homo sapiens, GI42794752, Length=198, Percent_Identity=32.8282828282828, Blast_Score=71, Evalue=6e-12,
Organism=Escherichia coli, GI1786801, Length=769, Percent_Identity=28.2184655396619, Blast_Score=242, Evalue=1e-64,
Organism=Escherichia coli, GI1786810, Length=492, Percent_Identity=24.7967479674797, Blast_Score=90, Evalue=8e-19,
Organism=Escherichia coli, GI145693145, Length=527, Percent_Identity=22.3908918406072, Blast_Score=81, Evalue=4e-16,
Organism=Escherichia coli, GI1789201, Length=412, Percent_Identity=26.9417475728155, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17556356, Length=573, Percent_Identity=23.0366492146597, Blast_Score=95, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17550940, Length=419, Percent_Identity=23.6276849642005, Blast_Score=84, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71985884, Length=292, Percent_Identity=25.3424657534247, Blast_Score=70, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6319591, Length=686, Percent_Identity=24.7813411078717, Blast_Score=164, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6319699, Length=365, Percent_Identity=23.013698630137, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24648676, Length=567, Percent_Identity=27.5132275132275, Blast_Score=151, Evalue=3e-36,
Organism=Drosophila melanogaster, GI18859661, Length=504, Percent_Identity=24.4047619047619, Blast_Score=80, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24656500, Length=367, Percent_Identity=24.7956403269755, Blast_Score=77, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR013624
- InterPro:   IPR006163
- InterPro:   IPR006162
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF08415 NRPS; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 124721; Mature: 124721

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAISRDEIKLTVADLIGLTAQDISDGDDLITLGLDSIRMMTLAGGWRKRGSRVTFAQLA
CCCCCCCCEEEEHHHHHCCHHHCCCCCCCEEEECCCHHHHHHHCCCHHHCCCEEEHHHHH
AEPSVDSWYALLRADDEVAPDEEAAADETDGQDGEDAPFPLATMQHAYWIGRSEDQELGG
CCCCHHHHHHHHCCCCCCCCCCHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHCC
VAAHLYVEFDGGAIDPDRLKAAVERLVAAHPMLRTKFLPDGTQQTMAAPGRDVFTVVDLR
EEEEEEEEECCCCCCHHHHHHHHHHHHHHCHHHHHCCCCCCCHHHHCCCCCCEEEEEEEC
GRAAGEVDAALAELREHKTHQRLAIEDGQVLDVTLTLRDDNNSRLHLDVDMLAGDAMSYR
CCCCCHHHHHHHHHHHHHHHHEEEECCCCEEEEEEEEECCCCCEEEEEEHHHCCCHHHHH
VLISDLAALYHGGAQPELGYSYRRYRTEDRGDAAAHERDRQWWQDRLADLPGAPELPVVP
HHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEC
VSERTDQHRTVRYNYWLEPEAKQQLLVAAHQRGITPAMAMAAVFAETIGGWSAQSRFLLN
CCCCCCCCCEEEEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEEE
VPLFHRESVHPDIDRVIGDFTSSIMLDVDLTEDMSVADRARALQRTMYESGAHSAYPGLN
CCCCCCCCCCCHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCHH
VLRDLGRHRGEPVLAPIVYTSALNLGELFAEPVMQTFGEPVWIISQGPQVLLDAQVTEVR
HHHHHHHHCCCCEEEHHHHHHHCCHHHHHHHHHHHHCCCCEEEEECCCCEEEECHHHHHC
GGLLLNWDVRESAFPHGMVAAMFERYTDAVAALCTGADGWNSDAAVRLPASQERVRRAVN
CCEEEEECCHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHC
ATAGPVTGRRLHEGFFDFAQSNPGMPAVVWGFGDEDGVWSYRDVAAQALAVAGALRERGV
CCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCC
RPGDCVAVQLPKGRDQIPAVLGVLAAGATYVPIGFDQPAQRRAAILETGGISVALTTADS
CCCCEEEEECCCCCCHHHHHHHHHHCCCEEEECCCCCCHHHHHHHEECCCEEEEEEECCC
DMPIDHLSIDAARQYPEPLREPVLPDASQIAYVLFTSGSTGTPKGVDVSHAAAMNTIDAL
CCCCHHCCHHHHHCCCHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHC
NDEFEVVTSDRALGLSALEFDLSVYDIFGMFSVGAAVVAVDAAQRAEATTWVELIRRHRV
CCCEEEEECCCCCCCCCEECCHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHH
SIINCVPGLLDMILAMGGGELGDSLRAVILGGDWVSSDLARRLAAQVPGCRFTGLGGATE
HHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCEEECCCCHHH
AAIHSTICEVLGDPPQHWATIPFGVPLRNVRCRVVSQAGRDCLDWVPGELWIGGDSVASG
HHHHHHHHHHHCCCHHHCEECCCCCCCCHHHHHHHHHCCCHHHHCCCCEEEECCHHHHCC
YRNDPERTAERFVEHDGLRWYRTGDMARYWPDGTIEFLGRADHQVKIRGYRVELGEVESA
CCCCHHHHHHHHHHHCCCEEEEECCCCEECCCCHHHHCCCCCCEEEEEEEEEEHHHHHHH
LRLIPGIRHAVAAVVGADAPNLVAAVAGTPDPAADYAALLGDLLPGYMIPARIELLEQMP
HHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCC
LTSNGKMDRRAVTALLEQVAVGGADAGPRHDLDAALVDLVSGVLGIESMGVHDDFFARGG
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHCCC
DSVLATAVIARVRDWLSVDHALVGDFFATRTVAGLADRLLQREADRGTPDRLAVVAGHYL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCEE
EIAAMTDEEVLAGTV
EEEEECCCHHHCCCC
>Mature Secondary Structure
MEAISRDEIKLTVADLIGLTAQDISDGDDLITLGLDSIRMMTLAGGWRKRGSRVTFAQLA
CCCCCCCCEEEEHHHHHCCHHHCCCCCCCEEEECCCHHHHHHHCCCHHHCCCEEEHHHHH
AEPSVDSWYALLRADDEVAPDEEAAADETDGQDGEDAPFPLATMQHAYWIGRSEDQELGG
CCCCHHHHHHHHCCCCCCCCCCHHCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHCC
VAAHLYVEFDGGAIDPDRLKAAVERLVAAHPMLRTKFLPDGTQQTMAAPGRDVFTVVDLR
EEEEEEEEECCCCCCHHHHHHHHHHHHHHCHHHHHCCCCCCCHHHHCCCCCCEEEEEEEC
GRAAGEVDAALAELREHKTHQRLAIEDGQVLDVTLTLRDDNNSRLHLDVDMLAGDAMSYR
CCCCCHHHHHHHHHHHHHHHHEEEECCCCEEEEEEEEECCCCCEEEEEEHHHCCCHHHHH
VLISDLAALYHGGAQPELGYSYRRYRTEDRGDAAAHERDRQWWQDRLADLPGAPELPVVP
HHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEC
VSERTDQHRTVRYNYWLEPEAKQQLLVAAHQRGITPAMAMAAVFAETIGGWSAQSRFLLN
CCCCCCCCCEEEEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCEEEEE
VPLFHRESVHPDIDRVIGDFTSSIMLDVDLTEDMSVADRARALQRTMYESGAHSAYPGLN
CCCCCCCCCCCHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCHH
VLRDLGRHRGEPVLAPIVYTSALNLGELFAEPVMQTFGEPVWIISQGPQVLLDAQVTEVR
HHHHHHHHCCCCEEEHHHHHHHCCHHHHHHHHHHHHCCCCEEEEECCCCEEEECHHHHHC
GGLLLNWDVRESAFPHGMVAAMFERYTDAVAALCTGADGWNSDAAVRLPASQERVRRAVN
CCEEEEECCHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHC
ATAGPVTGRRLHEGFFDFAQSNPGMPAVVWGFGDEDGVWSYRDVAAQALAVAGALRERGV
CCCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCC
RPGDCVAVQLPKGRDQIPAVLGVLAAGATYVPIGFDQPAQRRAAILETGGISVALTTADS
CCCCEEEEECCCCCCHHHHHHHHHHCCCEEEECCCCCCHHHHHHHEECCCEEEEEEECCC
DMPIDHLSIDAARQYPEPLREPVLPDASQIAYVLFTSGSTGTPKGVDVSHAAAMNTIDAL
CCCCHHCCHHHHHCCCHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHC
NDEFEVVTSDRALGLSALEFDLSVYDIFGMFSVGAAVVAVDAAQRAEATTWVELIRRHRV
CCCEEEEECCCCCCCCCEECCHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHH
SIINCVPGLLDMILAMGGGELGDSLRAVILGGDWVSSDLARRLAAQVPGCRFTGLGGATE
HHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCEEECCCCHHH
AAIHSTICEVLGDPPQHWATIPFGVPLRNVRCRVVSQAGRDCLDWVPGELWIGGDSVASG
HHHHHHHHHHHCCCHHHCEECCCCCCCCHHHHHHHHHCCCHHHHCCCCEEEECCHHHHCC
YRNDPERTAERFVEHDGLRWYRTGDMARYWPDGTIEFLGRADHQVKIRGYRVELGEVESA
CCCCHHHHHHHHHHHCCCEEEEECCCCEECCCCHHHHCCCCCCEEEEEEEEEEHHHHHHH
LRLIPGIRHAVAAVVGADAPNLVAAVAGTPDPAADYAALLGDLLPGYMIPARIELLEQMP
HHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCC
LTSNGKMDRRAVTALLEQVAVGGADAGPRHDLDAALVDLVSGVLGIESMGVHDDFFARGG
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHCCC
DSVLATAVIARVRDWLSVDHALVGDFFATRTVAGLADRLLQREADRGTPDRLAVVAGHYL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCEE
EIAAMTDEEVLAGTV
EEEEECCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]