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The map label for this gene is bah [H]

Identifier: 169629162

GI number: 169629162

Start: 2075164

End: 2076129

Strand: Direct

Name: bah [H]

Synonym: MAB_2076

Alternate gene names: 169629162

Gene position: 2075164-2076129 (Clockwise)

Preceding gene: 169629161

Following gene: 169629163

Centisome position: 40.95

GC content: 62.84

Gene sequence:

>966_bases
ATGACCAGGATGGATGCCCCCGACTGGCAGCCCAGTCTTGCCAGTCATCTCGTCGCGATGTCCTCGCGAACCACGCTGCG
GCCACTGGCGCAGCTGATGCCATCAAACGCCTACGGACTTGCGGTGATGGATCGCGTGCTTCGAACAGCGCTCGTAGCCT
CACGGCCTCGGCGCGGCGTCACAGTGCGCAAGGTTGACACTGTATTCGCCGGAGGCCCGGTTCGTGGGGACTGGATCACC
ACGCCTGCCATTAATCCGCATGCCAACCCTTTGCTGTACATCCACGGCGGCGCCTATTCTATGTGCTCGCCGGAGACGCA
CCGCGGTCTTCTCGGTGAACTCGCCTCGGCGAGCGGGCGCCCCATCTTCGCAGTGAAGTATCGTCTTGCCCCGCGGTATC
CCTATCCCGCAGCCGCGGACGATGCGCTGAATGCGTATCGCTGGCTTACCAGCGGAGGGTCCCCGGGTTCTTGTCAGCGC
ACCGTCGCGGTTGCCGGCGATTCAGCGGGCGGTCAGCTCACGATGGCCACGGCCTTGGGCGCACGTGCAGTTGGATTGCC
GCTCCCTGATGCGATGCTGCTGATGTCTCCCGTCCTGGATCTCAGGTGCGAACTTGCCAGAGCGCGTGAAATTCGCCGCC
GGGATCCTTTTGCCTCCGCTCAATCAGCGGCGCGCGCTCTTGACCTCTACGTAGGTGGCGCAGATCGCGGAGATCCGCGC
CTCAGCGTGCTTGACGCGGACCTCACCTCGATGCCGCCGATCCTCATTCAGGTGGGCGGGAGAGAAATGTTGATCGATGA
CTCGCGCCGTCTCGCCGAGCGACTTCAATCAGCTGGATCCCACGTCGAGATCCAGGTATACCGGGGACAGATCCATGTAT
TCCAGGCTATGTTCCGGATTCTTCCCGAAGCCCGAGACGCGATTCATCGAGCGGGACGCTTCCTTGAAGCCTCGGAAGTC
AGGTGA

Upstream 100 bases:

>100_bases
CACTGCGTCCCTCAACGACTTTTGAGACGTATTGGCGAAGCCGCACCTTTCGCCTCTCGGATTACCAATTCGAGAATCGG
GCCGAGGTGGTGGGTGCCCG

Downstream 100 bases:

>100_bases
AAGTGTCCGAACAGGCAATGCTCCTACACCTACACCACCTCGACCGCCGCAGCGTGAAGTCAGTCGTCTCTGCCTCATGA
GCAGCAACTTCGCGACGGCC

Product: putative esterase/acetyl hydrolase

Products: alcohol; a carboxylate [C]

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MTRMDAPDWQPSLASHLVAMSSRTTLRPLAQLMPSNAYGLAVMDRVLRTALVASRPRRGVTVRKVDTVFAGGPVRGDWIT
TPAINPHANPLLYIHGGAYSMCSPETHRGLLGELASASGRPIFAVKYRLAPRYPYPAAADDALNAYRWLTSGGSPGSCQR
TVAVAGDSAGGQLTMATALGARAVGLPLPDAMLLMSPVLDLRCELARAREIRRRDPFASAQSAARALDLYVGGADRGDPR
LSVLDADLTSMPPILIQVGGREMLIDDSRRLAERLQSAGSHVEIQVYRGQIHVFQAMFRILPEARDAIHRAGRFLEASEV
R

Sequences:

>Translated_321_residues
MTRMDAPDWQPSLASHLVAMSSRTTLRPLAQLMPSNAYGLAVMDRVLRTALVASRPRRGVTVRKVDTVFAGGPVRGDWIT
TPAINPHANPLLYIHGGAYSMCSPETHRGLLGELASASGRPIFAVKYRLAPRYPYPAAADDALNAYRWLTSGGSPGSCQR
TVAVAGDSAGGQLTMATALGARAVGLPLPDAMLLMSPVLDLRCELARAREIRRRDPFASAQSAARALDLYVGGADRGDPR
LSVLDADLTSMPPILIQVGGREMLIDDSRRLAERLQSAGSHVEIQVYRGQIHVFQAMFRILPEARDAIHRAGRFLEASEV
R
>Mature_320_residues
TRMDAPDWQPSLASHLVAMSSRTTLRPLAQLMPSNAYGLAVMDRVLRTALVASRPRRGVTVRKVDTVFAGGPVRGDWITT
PAINPHANPLLYIHGGAYSMCSPETHRGLLGELASASGRPIFAVKYRLAPRYPYPAAADDALNAYRWLTSGGSPGSCQRT
VAVAGDSAGGQLTMATALGARAVGLPLPDAMLLMSPVLDLRCELARAREIRRRDPFASAQSAARALDLYVGGADRGDPRL
SVLDADLTSMPPILIQVGGREMLIDDSRRLAERLQSAGSHVEIQVYRGQIHVFQAMFRILPEARDAIHRAGRFLEASEVR

Specific function: This protein removes the N-acetyl group from bialaphos as one of the final steps of the bialaphos biosynthetic pathway [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDXG' lipolytic enzyme family [H]

Homologues:

Organism=Homo sapiens, GI21328446, Length=143, Percent_Identity=30.0699300699301, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1786682, Length=232, Percent_Identity=26.2931034482759, Blast_Score=78, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI115533410, Length=146, Percent_Identity=28.7671232876712, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI115533412, Length=146, Percent_Identity=28.7671232876712, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24656084, Length=112, Percent_Identity=35.7142857142857, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24656076, Length=112, Percent_Identity=35.7142857142857, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI20130169, Length=112, Percent_Identity=35.7142857142857, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013094
- InterPro:   IPR002168 [H]

Pfam domain/function: PF07859 Abhydrolase_3 [H]

EC number: 3.1.1.- [C]

Molecular weight: Translated: 34714; Mature: 34583

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: PS01173 LIPASE_GDXG_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRMDAPDWQPSLASHLVAMSSRTTLRPLAQLMPSNAYGLAVMDRVLRTALVASRPRRGV
CCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCE
TVRKVDTVFAGGPVRGDWITTPAINPHANPLLYIHGGAYSMCSPETHRGLLGELASASGR
EEEEEEEEEECCCCCCCEEECCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCC
PIFAVKYRLAPRYPYPAAADDALNAYRWLTSGGSPGSCQRTVAVAGDSAGGQLTMATALG
EEEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEEEEEEHHC
ARAVGLPLPDAMLLMSPVLDLRCELARAREIRRRDPFASAQSAARALDLYVGGADRGDPR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEEEEEECCCCCCCCC
LSVLDADLTSMPPILIQVGGREMLIDDSRRLAERLQSAGSHVEIQVYRGQIHVFQAMFRI
EEEEECCHHHCCCEEEEECCCEEEECCHHHHHHHHHHCCCEEEEEEEECHHHHHHHHHHH
LPEARDAIHRAGRFLEASEVR
HHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TRMDAPDWQPSLASHLVAMSSRTTLRPLAQLMPSNAYGLAVMDRVLRTALVASRPRRGV
CCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCE
TVRKVDTVFAGGPVRGDWITTPAINPHANPLLYIHGGAYSMCSPETHRGLLGELASASGR
EEEEEEEEEECCCCCCCEEECCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCC
PIFAVKYRLAPRYPYPAAADDALNAYRWLTSGGSPGSCQRTVAVAGDSAGGQLTMATALG
EEEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEEEEEEHHC
ARAVGLPLPDAMLLMSPVLDLRCELARAREIRRRDPFASAQSAARALDLYVGGADRGDPR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEEEEEECCCCCCCCC
LSVLDADLTSMPPILIQVGGREMLIDDSRRLAERLQSAGSHVEIQVYRGQIHVFQAMFRI
EEEEECCHHHCCCEEEEECCCEEEECCHHHHHHHHHHCCCEEEEEEEECHHHHHHHHHHH
LPEARDAIHRAGRFLEASEVR
HHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Carboxylic ester; H2O [C]

Specific reaction: Carboxylic ester + H2O = an alcohol + carboxylate [C]

General reaction: Hydrolase; Acting on ester bonds; Carboxylic ester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2066341 [H]