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The map label for this gene is phoP [H]

Identifier: 169628810

GI number: 169628810

Start: 1751067

End: 1751750

Strand: Direct

Name: phoP [H]

Synonym: MAB_1720

Alternate gene names: 169628810

Gene position: 1751067-1751750 (Clockwise)

Preceding gene: 169628809

Following gene: 169628811

Centisome position: 34.56

GC content: 68.42

Gene sequence:

>684_bases
GTGCCCAGCCAGCGAAGAATCTTGGTCGTTGACGACGAACCCACGATCTGTGCGTCCATTTCCGCACGGCTGCGCGCCGA
GGGGTATGCGGTAGACACCGAGGACAACGGCCTGGACGCGGTGCGGCATTGCCGCGAAAACCCGCCGGACCTGATGGTGC
TGGATGTCATGCTGCCCGGACTCGACGGGCTGGAGGTGTGCCGCCAGGTGCAGGCCCACGCACCCATCCCGGTGCTGATG
CTCACCGCGCGGGGCACCGAAACCGACATGCTGGTGGGCCTGGGGGTGGGGGCCGACGACTACCTGCCCAAGCCCTTCAG
CATGCGGGTGCTGGTGGCCCGGGTGGCCGCGCTGCTGCGCCGCACCCATCGGATCGCGCCGCCGAGCACCGATGTGCGCA
TCGGGCAGGTACGCATCGACGTGTCCGAGCGCCGCGTATATCACCGCGACGACGAGGTGCACCTGACCCGCACCGAATTC
GACCTACTGGCCTACCTGGCCGACAACCCGCGGGTGGCCATCAGTCGTGATCGTCTGCTCGATCAGGTGTGGGGCTGGAG
CGCGGGGCTGCCCTCGGGGCGGCGCACCGTGGACAGTCACATCAAGGCGCTGCGCCGCAAGCTCGGTCAGGAGCTGATCC
GCACCGTCCACGGCATCGGATACGCGTTGGAGGCACCGCGATGA

Upstream 100 bases:

>100_bases
CGTCGGTCAGCGCGGCGCAGTAAGGGGGCCGGGAAGGGTCTCCACAGAACCTTCACAAAAGGCTCCAGCCATCCCCACAA
CCGTCAAATAACCTGTTCAT

Downstream 100 bases:

>100_bases
GCCAACTGCTGGAACTGCTGCCGCGCCCGCTGGATCCGTTGCGCTCGTTCAAGTTCAAAACGGCGGTGCTGGTGGGGGTG
GCGCTGCTGATCGCCACCTG

Product: putative two-component system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MPSQRRILVVDDEPTICASISARLRAEGYAVDTEDNGLDAVRHCRENPPDLMVLDVMLPGLDGLEVCRQVQAHAPIPVLM
LTARGTETDMLVGLGVGADDYLPKPFSMRVLVARVAALLRRTHRIAPPSTDVRIGQVRIDVSERRVYHRDDEVHLTRTEF
DLLAYLADNPRVAISRDRLLDQVWGWSAGLPSGRRTVDSHIKALRRKLGQELIRTVHGIGYALEAPR

Sequences:

>Translated_227_residues
MPSQRRILVVDDEPTICASISARLRAEGYAVDTEDNGLDAVRHCRENPPDLMVLDVMLPGLDGLEVCRQVQAHAPIPVLM
LTARGTETDMLVGLGVGADDYLPKPFSMRVLVARVAALLRRTHRIAPPSTDVRIGQVRIDVSERRVYHRDDEVHLTRTEF
DLLAYLADNPRVAISRDRLLDQVWGWSAGLPSGRRTVDSHIKALRRKLGQELIRTVHGIGYALEAPR
>Mature_226_residues
PSQRRILVVDDEPTICASISARLRAEGYAVDTEDNGLDAVRHCRENPPDLMVLDVMLPGLDGLEVCRQVQAHAPIPVLML
TARGTETDMLVGLGVGADDYLPKPFSMRVLVARVAALLRRTHRIAPPSTDVRIGQVRIDVSERRVYHRDDEVHLTRTEFD
LLAYLADNPRVAISRDRLLDQVWGWSAGLPSGRRTVDSHIKALRRKLGQELIRTVHGIGYALEAPR

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=42.6008968609865, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=40.4444444444444, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI1789809, Length=234, Percent_Identity=36.7521367521368, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=39.2070484581498, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=34.5132743362832, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1789402, Length=219, Percent_Identity=36.986301369863, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1790552, Length=221, Percent_Identity=36.6515837104072, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1786911, Length=220, Percent_Identity=35.4545454545455, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI87082012, Length=226, Percent_Identity=33.6283185840708, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=36.4444444444444, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=32.15859030837, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=33.6244541484716, Blast_Score=110, Evalue=9e-26,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=32.1428571428571, Blast_Score=107, Evalue=4e-25,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=32.2033898305085, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790437, Length=135, Percent_Identity=36.2962962962963, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790299, Length=139, Percent_Identity=30.9352517985612, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1788713, Length=128, Percent_Identity=31.25, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788550, Length=109, Percent_Identity=29.3577981651376, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25349; Mature: 25217

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSQRRILVVDDEPTICASISARLRAEGYAVDTEDNGLDAVRHCRENPPDLMVLDVMLPG
CCCCCEEEEECCCCCEEHHHHHHHEECCEEECCCCCCHHHHHHHHCCCCCEEEEEECCCC
LDGLEVCRQVQAHAPIPVLMLTARGTETDMLVGLGVGADDYLPKPFSMRVLVARVAALLR
CCHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
RTHRIAPPSTDVRIGQVRIDVSERRVYHRDDEVHLTRTEFDLLAYLADNPRVAISRDRLL
HHHCCCCCCCCEEEEEEEEEHHHCEEEECCCCEEEEHHHHHHHEEECCCCCEEEEHHHHH
DQVWGWSAGLPSGRRTVDSHIKALRRKLGQELIRTVHGIGYALEAPR
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCC
>Mature Secondary Structure 
PSQRRILVVDDEPTICASISARLRAEGYAVDTEDNGLDAVRHCRENPPDLMVLDVMLPG
CCCCEEEEECCCCCEEHHHHHHHEECCEEECCCCCCHHHHHHHHCCCCCEEEEEECCCC
LDGLEVCRQVQAHAPIPVLMLTARGTETDMLVGLGVGADDYLPKPFSMRVLVARVAALLR
CCHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHH
RTHRIAPPSTDVRIGQVRIDVSERRVYHRDDEVHLTRTEFDLLAYLADNPRVAISRDRLL
HHHCCCCCCCCEEEEEEEEEHHHCEEEECCCCEEEEHHHHHHHEEECCCCCEEEEHHHHH
DQVWGWSAGLPSGRRTVDSHIKALRRKLGQELIRTVHGIGYALEAPR
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]