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The map label for this gene is ccmC [H]

Identifier: 16767102

GI number: 16767102

Start: 4016528

End: 4017265

Strand: Reverse

Name: ccmC [H]

Synonym: STM3817

Alternate gene names: 16767102

Gene position: 4017265-4016528 (Counterclockwise)

Preceding gene: 16767103

Following gene: 16767101

Centisome position: 82.7

GC content: 65.45

Gene sequence:

>738_bases
ATGTGGAAAACCCTTCATCAGCTGGCGGCGCCGCCCCGGCTGTATCAGATTTGCGGCAGGCTCGTGCCGTGGCTGGCGGC
GGCCGGCATCATTGTGCTGGCCACGGGCTGGGTCCGGGGCTTTGGTTTCGCCCCGGCGGACTACCAGCAGGGGGAGGGCT
ACCGCATTATGTACCTGCATGTCCCGGCGGCCATCTGGTCGATGGGTATCTATGCGGCGATGGCGGTGGCGGCGTTCACC
GGGCTGGTCTGGCAGATGAAAATGGCCAGCCTTGCCGTCGCGGCGATGGCGCCGGTGGGGGCGGTGTACACCTTCATCGC
GCTGGTCACCGGCGCGGCGTGGGGCAAACCGATGTGGGGCACCTGGTGGGTGTGGGACGCGCGCCTGACCTCGGAGCTGG
TGCTGCTGTTTCTCTACGCCGGGGTCATCGCCCTGTGGCACGCCTTTGACGACCGTAAAATGGCCGGGCGCGCGGCGGGC
ATTCTGGTGCTGGTCGGCGTGGTGAACCTGCCGGTTATCCACTATTCCGTCGAGTGGTGGAACACCCTGCACCAGGGCTC
GACGCGGATGCAGCAGAGTATCGACCCGGCGATGCGCTCGCCGCTGCGCTGGGCCATCGCCGGCTACCTGCTGCTCTTTA
TGACGCTTTCGCTGATGCGGATGCGCAACCTGATTTTACTGATGGAAAAACGCCGCCCGTGGGTGAGCGAACTGATACTG
AAAAGGGGGCACCGGTGA

Upstream 100 bases:

>100_bases
GTTAAGCCCGTTCGCCACCGCGGCGGCGCTGCGCCTCAGCGTGCAGTAGCGCCCCGGCGCGACGGACATTTTACTGGTTT
CAGGAGGTCAGGTGACGACT

Downstream 100 bases:

>100_bases
GTCCGGCATTTTCATCGTGGAGCGATTTTTTCGCCATGGGCGGGTACGCCTTTTTTGTCTGGCTGGCGGTGGCGATGACC
GTGGCGCCGCTGGCGCTGCT

Product: heme exporter protein

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CcmC [H]

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MWKTLHQLAAPPRLYQICGRLVPWLAAAGIIVLATGWVRGFGFAPADYQQGEGYRIMYLHVPAAIWSMGIYAAMAVAAFT
GLVWQMKMASLAVAAMAPVGAVYTFIALVTGAAWGKPMWGTWWVWDARLTSELVLLFLYAGVIALWHAFDDRKMAGRAAG
ILVLVGVVNLPVIHYSVEWWNTLHQGSTRMQQSIDPAMRSPLRWAIAGYLLLFMTLSLMRMRNLILLMEKRRPWVSELIL
KRGHR

Sequences:

>Translated_245_residues
MWKTLHQLAAPPRLYQICGRLVPWLAAAGIIVLATGWVRGFGFAPADYQQGEGYRIMYLHVPAAIWSMGIYAAMAVAAFT
GLVWQMKMASLAVAAMAPVGAVYTFIALVTGAAWGKPMWGTWWVWDARLTSELVLLFLYAGVIALWHAFDDRKMAGRAAG
ILVLVGVVNLPVIHYSVEWWNTLHQGSTRMQQSIDPAMRSPLRWAIAGYLLLFMTLSLMRMRNLILLMEKRRPWVSELIL
KRGHR
>Mature_245_residues
MWKTLHQLAAPPRLYQICGRLVPWLAAAGIIVLATGWVRGFGFAPADYQQGEGYRIMYLHVPAAIWSMGIYAAMAVAAFT
GLVWQMKMASLAVAAMAPVGAVYTFIALVTGAAWGKPMWGTWWVWDARLTSELVLLFLYAGVIALWHAFDDRKMAGRAAG
ILVLVGVVNLPVIHYSVEWWNTLHQGSTRMQQSIDPAMRSPLRWAIAGYLLLFMTLSLMRMRNLILLMEKRRPWVSELIL
KRGHR

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG0755

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmC/CycZ/HelC family [H]

Homologues:

Organism=Escherichia coli, GI1788527, Length=245, Percent_Identity=86.1224489795918, Blast_Score=436, Evalue=1e-124,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003557 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 27556; Mature: 27556

Theoretical pI: Translated: 10.69; Mature: 10.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
6.1 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWKTLHQLAAPPRLYQICGRLVPWLAAAGIIVLATGWVRGFGFAPADYQQGEGYRIMYLH
CCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEE
VPAAIWSMGIYAAMAVAAFTGLVWQMKMASLAVAAMAPVGAVYTFIALVTGAAWGKPMWG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
TWWVWDARLTSELVLLFLYAGVIALWHAFDDRKMAGRAAGILVLVGVVNLPVIHYSVEWW
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHEEEHHHH
NTLHQGSTRMQQSIDPAMRSPLRWAIAGYLLLFMTLSLMRMRNLILLMEKRRPWVSELIL
HHHHHHHHHHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
KRGHR
HCCCC
>Mature Secondary Structure
MWKTLHQLAAPPRLYQICGRLVPWLAAAGIIVLATGWVRGFGFAPADYQQGEGYRIMYLH
CCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEE
VPAAIWSMGIYAAMAVAAFTGLVWQMKMASLAVAAMAPVGAVYTFIALVTGAAWGKPMWG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
TWWVWDARLTSELVLLFLYAGVIALWHAFDDRKMAGRAAGILVLVGVVNLPVIHYSVEWW
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHEEEHHHH
NTLHQGSTRMQQSIDPAMRSPLRWAIAGYLLLFMTLSLMRMRNLILLMEKRRPWVSELIL
HHHHHHHHHHHHHCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
KRGHR
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]