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The map label for this gene is manX [C]

Identifier: 16767056

GI number: 16767056

Start: 3971905

End: 3972330

Strand: Reverse

Name: manX [C]

Synonym: STM3772

Alternate gene names: 16767056

Gene position: 3972330-3971905 (Counterclockwise)

Preceding gene: 16767057

Following gene: 16767055

Centisome position: 81.78

GC content: 59.62

Gene sequence:

>426_bases
TTGACTACCACACAACCGTTGCCCCACATCCTGCTGCTGACGCATGGCGGCTGGGGACAACCGCTTTGCAACAGCCTGCG
TATGGTCACGGGCGAAATTAAAGGCGTGACGGAAATCGCGCTAATGCCTGTCGATACGCTGGGCGAGTTTTATCAACGCG
TCGAGGCCGTGGTGAAAACGCTGCCGGAAGGCTCGCTGATCCTGACGGATTTTGTCGGCGGCACAACGTCCAACGTCGCG
GCGCGGCTAAGCGCCGATTATCCGGTGGCGGTGATTGCCGGACTGAATGCGTCGCTACTGCTGGAGGCGCTGGACAGGCG
CGAACAAGGGATGCTAACCGCCTGCGTGGACGAGTTAGTTGAGGCCGGGCGCAGTAGCTGCCTGGATGTGGTCGCCCATG
TACGTCAGCTACAACAATCACTCTAA

Upstream 100 bases:

>100_bases
CCTTATCCGGCCTACCGGGAGTGTCCTGTAGGCCCGGTAAGCGCAGTGCCACCGGGCAATATATGCCGGTGTCCTCATGT
AATTGCGCCAGGAGGCCATT

Downstream 100 bases:

>100_bases
GGAAAACATCATGGCCAATATCGTTTTATGCCGCATCGACAGCCGTCTCATTCATGGACAGGTTGTCACGAAGTGGGTCG
GACAATCTCAGGCGAACCGG

Product: phosphotransferase system enzyme IIA

Products: protein histidine; sugar phosphate

Alternate protein names: Phosphotransferase System IIA; Mannose-Specific PTS System Component IIA; PTS System Protein; PTS System IIA Component

Number of amino acids: Translated: 141; Mature: 140

Protein sequence:

>141_residues
MTTTQPLPHILLLTHGGWGQPLCNSLRMVTGEIKGVTEIALMPVDTLGEFYQRVEAVVKTLPEGSLILTDFVGGTTSNVA
ARLSADYPVAVIAGLNASLLLEALDRREQGMLTACVDELVEAGRSSCLDVVAHVRQLQQSL

Sequences:

>Translated_141_residues
MTTTQPLPHILLLTHGGWGQPLCNSLRMVTGEIKGVTEIALMPVDTLGEFYQRVEAVVKTLPEGSLILTDFVGGTTSNVA
ARLSADYPVAVIAGLNASLLLEALDRREQGMLTACVDELVEAGRSSCLDVVAHVRQLQQSL
>Mature_140_residues
TTTQPLPHILLLTHGGWGQPLCNSLRMVTGEIKGVTEIALMPVDTLGEFYQRVEAVVKTLPEGSLILTDFVGGTTSNVAA
RLSADYPVAVIAGLNASLLLEALDRREQGMLTACVDELVEAGRSSCLDVVAHVRQLQQSL

Specific function: This Is A Component Of The Phosphoenolpyruvate-Dependent Sugar Phosphotransferase System (Pts), A Major Carbohydrate Active -Transport System. The IIcd Domains Contain The Sugar Binding Site And The Transmembrane Channel; The IIa Domain Contains The Prim

COG id: COG2893

COG function: function code G; Phosphotransferase system, mannose/fructose-specific component IIA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2880 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 260 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.1.69

Molecular weight: Translated: 15085; Mature: 14953

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS51096 PTS_EIIA_TYPE_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTQPLPHILLLTHGGWGQPLCNSLRMVTGEIKGVTEIALMPVDTLGEFYQRVEAVVKT
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHH
LPEGSLILTDFVGGTTSNVAARLSADYPVAVIAGLNASLLLEALDRREQGMLTACVDELV
CCCCCEEEEECCCCCCHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHH
EAGRSSCLDVVAHVRQLQQSL
HHCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTTQPLPHILLLTHGGWGQPLCNSLRMVTGEIKGVTEIALMPVDTLGEFYQRVEAVVKT
CCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHH
LPEGSLILTDFVGGTTSNVAARLSADYPVAVIAGLNASLLLEALDRREQGMLTACVDELV
CCCCCEEEEECCCCCCHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHH
EAGRSSCLDVVAHVRQLQQSL
HHCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: Transferring phosphorus-containing groups; Phosphotransferases with an alcohol group as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA