Click here to switch to the map view.

The map label for this gene is recD [H]

Identifier: 16766295

GI number: 16766295

Start: 3144276

End: 3146111

Strand: Reverse

Name: recD [H]

Synonym: STM2993

Alternate gene names: 16766295

Gene position: 3146111-3144276 (Counterclockwise)

Preceding gene: 16766296

Following gene: 16766293

Centisome position: 64.77

GC content: 58.22

Gene sequence:

>1836_bases
ATGACAATCCAGGAGCGGTTGCTGGAGGCCGTTGAACAAAAACTCTTACGGCCCATTGATGCCCAGTTTGCTTTAACCGT
CGCCGGTAACGACGATCCCGCCGTGACGCTGGCGGCAGCGCTGCTTAGTCATGACGCAGGTGAAGGTCACGTGTGTCTGC
CGTTGTCGCGTTTAACGTTAACGGAGGAGGCGCATCCCTTACTGGTCGCCTGTATAAGCGAAACGGCTACGCCAATCGAC
TGGAAAAAGCGGTTACTGGCGTCTGCGGCGGTTAGCTGCGGCGATAGCCCCGCGCCGTTAATTCTGTGCGGCGAGCGTCT
CTACCTGAATCGCATGTGGTGCAACGAACGTACGGTTGCGCGCTTTTTTAACGAGGTTAACCAGGCCATCGCCGTAGATG
AAGATCAGTTATCCCGTATTCTGGACGCGCTATTCCCTCCGACAGACGAGGTGAACTGGCAAAAGGTGGCCGCCGCCGTA
GCGCTAACTCGCCGTATCTCCGTGATTTCAGGCGGTCCCGGCACCGGTAAAACCACCACCGTCGCGAAGCTGCTGGCGGC
ATTAATTCAAATGGCGGATGGCGAACGTTGCCGTATCCGGCTGGCAGCGCCGACCGGGAAAGCGGCCGCACGCCTGACGG
AGTCGCTCGGCGCGGCGTTGCGTCAGCTTCCTCTTACCGATGCGCAGAAAAAGCGTATACCGGAGGACGCCAGTACGCTG
CACCGACTGCTAGGCGCACAGCCCGGCAGCCAACGATTACGCCATCATGCGGGCAACCCGCTACATCTGGACGTGCTGGT
GGTCGATGAAGCATCAATGATTGATTTGCCGATGATGTCACGTTTGATTGACTCTCTGCCGCCGCACGGGCGGGTCATTT
TTCTTGGCGATCGCGATCAGTTGGCATCCGTTGAGGCGGGCGCTGTGTTGGGCGATATTTGCGCCTATGTCAACGCAGGG
TTTACGGCGGAACGCGCCCGACAGCTAAGTCGACTCACTGGTAGCGCCATTCCGGCGGGGGCCGGAACGCAAGCCGCATC
TTTACGCGATAGCCTCTGTTTGTTGCAAAAGAGCTATCGTTTCGGCAGCGATTCTGGCATCGGCAAGCTGGCGGCGGCAA
TTAACTGCGGCGACAGGTCGGCAATCCAGGCTGTTTTTCAGCAGGGGTTTAGCGATATAGAGAAGCGTACATTGCAAAGC
AGCGACGATTATGCCGGGATGCTGGATGAAGCGCTGGCGGGCTATGGTCGCTACCTGCGGTTGCTGCATGAAAAAGCGAC
GCCGGAGGCAATCCTTCAGGCTTTCAATGAGTATCAACTGCTTTGTGCGCTGCGCGAAGGCCCATTTGGCGTGAGGGGAT
TGAATGACCGCATTGAGCAGGCGATGGTGCAGCAACGAAAAATTCAGCGGCACCCGCATTCTCGCTGGTACGAAGGGCGT
CCGGTAATGATTGCGCGCAACGATAGCGCGTTGGGGCTATTTAACGGCGATATTGGTATTGCGCTCGATCGCGGGCAGGG
GTTACGCGTCTGGTTTGTGATGCCGGACGGCACGATCAAGTCCGTTCAGCCCAGCCGTCTGCCGGAACATGATACAACCT
GGGCGATGACGGTACATAAATCACAGGGGTCTGAATTTGATCACGCCGCGCTGATTTTACCCAGCCAGCGTTCGCCGGTC
GTGACGCGGGAGCTGGTGTATACCGCTGTTACGCGAGCGCGGCGGCGGTTATCGCTGTATGCCGATGAACGGATCCTGGC
AGGCGCGATTGTGACGCGTACGGAGCGGCGCAGCGGGCTAGCCACCTTATTTGATGAAGTCAGTCGTACCGGATAA

Upstream 100 bases:

>100_bases
GCGAACGTCCGCAGCAGGGTATTTTTACCACTCGTCCTGCGGCGGCGTTAATTAACCAACTGGATGATATGTTTGCAGGT
GAAATGAGTGAGGAGGCGCA

Downstream 100 bases:

>100_bases
GACGAGTTCTCGCCGGATGGCGACGCGTAGCGTCTTATCCGGCCTCCAAATGATGCTTTCGAGCGTAGGCCTGATAAGCG
CAGCGCCATCAGGCCCCCCT

Product: exonuclease V subunit alpha

Products: NA

Alternate protein names: Exodeoxyribonuclease V 67 kDa polypeptide [H]

Number of amino acids: Translated: 611; Mature: 610

Protein sequence:

>611_residues
MTIQERLLEAVEQKLLRPIDAQFALTVAGNDDPAVTLAAALLSHDAGEGHVCLPLSRLTLTEEAHPLLVACISETATPID
WKKRLLASAAVSCGDSPAPLILCGERLYLNRMWCNERTVARFFNEVNQAIAVDEDQLSRILDALFPPTDEVNWQKVAAAV
ALTRRISVISGGPGTGKTTTVAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGAALRQLPLTDAQKKRIPEDASTL
HRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDSLPPHGRVIFLGDRDQLASVEAGAVLGDICAYVNAG
FTAERARQLSRLTGSAIPAGAGTQAASLRDSLCLLQKSYRFGSDSGIGKLAAAINCGDRSAIQAVFQQGFSDIEKRTLQS
SDDYAGMLDEALAGYGRYLRLLHEKATPEAILQAFNEYQLLCALREGPFGVRGLNDRIEQAMVQQRKIQRHPHSRWYEGR
PVMIARNDSALGLFNGDIGIALDRGQGLRVWFVMPDGTIKSVQPSRLPEHDTTWAMTVHKSQGSEFDHAALILPSQRSPV
VTRELVYTAVTRARRRLSLYADERILAGAIVTRTERRSGLATLFDEVSRTG

Sequences:

>Translated_611_residues
MTIQERLLEAVEQKLLRPIDAQFALTVAGNDDPAVTLAAALLSHDAGEGHVCLPLSRLTLTEEAHPLLVACISETATPID
WKKRLLASAAVSCGDSPAPLILCGERLYLNRMWCNERTVARFFNEVNQAIAVDEDQLSRILDALFPPTDEVNWQKVAAAV
ALTRRISVISGGPGTGKTTTVAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGAALRQLPLTDAQKKRIPEDASTL
HRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDSLPPHGRVIFLGDRDQLASVEAGAVLGDICAYVNAG
FTAERARQLSRLTGSAIPAGAGTQAASLRDSLCLLQKSYRFGSDSGIGKLAAAINCGDRSAIQAVFQQGFSDIEKRTLQS
SDDYAGMLDEALAGYGRYLRLLHEKATPEAILQAFNEYQLLCALREGPFGVRGLNDRIEQAMVQQRKIQRHPHSRWYEGR
PVMIARNDSALGLFNGDIGIALDRGQGLRVWFVMPDGTIKSVQPSRLPEHDTTWAMTVHKSQGSEFDHAALILPSQRSPV
VTRELVYTAVTRARRRLSLYADERILAGAIVTRTERRSGLATLFDEVSRTG
>Mature_610_residues
TIQERLLEAVEQKLLRPIDAQFALTVAGNDDPAVTLAAALLSHDAGEGHVCLPLSRLTLTEEAHPLLVACISETATPIDW
KKRLLASAAVSCGDSPAPLILCGERLYLNRMWCNERTVARFFNEVNQAIAVDEDQLSRILDALFPPTDEVNWQKVAAAVA
LTRRISVISGGPGTGKTTTVAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGAALRQLPLTDAQKKRIPEDASTLH
RLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDSLPPHGRVIFLGDRDQLASVEAGAVLGDICAYVNAGF
TAERARQLSRLTGSAIPAGAGTQAASLRDSLCLLQKSYRFGSDSGIGKLAAAINCGDRSAIQAVFQQGFSDIEKRTLQSS
DDYAGMLDEALAGYGRYLRLLHEKATPEAILQAFNEYQLLCALREGPFGVRGLNDRIEQAMVQQRKIQRHPHSRWYEGRP
VMIARNDSALGLFNGDIGIALDRGQGLRVWFVMPDGTIKSVQPSRLPEHDTTWAMTVHKSQGSEFDHAALILPSQRSPVV
TRELVYTAVTRARRRLSLYADERILAGAIVTRTERRSGLATLFDEVSRTG

Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recD family [H]

Homologues:

Organism=Escherichia coli, GI1789182, Length=604, Percent_Identity=84.4370860927152, Blast_Score=1024, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007807
- InterPro:   IPR006344
- InterPro:   IPR000606 [H]

Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]

EC number: =3.1.11.5 [H]

Molecular weight: Translated: 66526; Mature: 66395

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIQERLLEAVEQKLLRPIDAQFALTVAGNDDPAVTLAAALLSHDAGEGHVCLPLSRLTL
CCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEEHHHEE
TEEAHPLLVACISETATPIDWKKRLLASAAVSCGDSPAPLILCGERLYLNRMWCNERTVA
CCCCCCHHHEEHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHCCHHHHH
RFFNEVNQAIAVDEDQLSRILDALFPPTDEVNWQKVAAAVALTRRISVISGGPGTGKTTT
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHEEEECCCCCCCHHH
VAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGAALRQLPLTDAQKKRIPEDASTL
HHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHH
HRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDSLPPHGRVIFLGDRDQ
HHHHCCCCCHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCCCCEEEEEECCHH
LASVEAGAVLGDICAYVNAGFTAERARQLSRLTGSAIPAGAGTQAASLRDSLCLLQKSYR
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHC
FGSDSGIGKLAAAINCGDRSAIQAVFQQGFSDIEKRTLQSSDDYAGMLDEALAGYGRYLR
CCCCCCHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LLHEKATPEAILQAFNEYQLLCALREGPFGVRGLNDRIEQAMVQQRKIQRHPHSRWYEGR
HHHHCCCHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
PVMIARNDSALGLFNGDIGIALDRGQGLRVWFVMPDGTIKSVQPSRLPEHDTTWAMTVHK
EEEEEECCCEEEEEECCEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEC
SQGSEFDHAALILPSQRSPVVTRELVYTAVTRARRRLSLYADERILAGAIVTRTERRSGL
CCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHH
ATLFDEVSRTG
HHHHHHHHCCC
>Mature Secondary Structure 
TIQERLLEAVEQKLLRPIDAQFALTVAGNDDPAVTLAAALLSHDAGEGHVCLPLSRLTL
CHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEEHHHEE
TEEAHPLLVACISETATPIDWKKRLLASAAVSCGDSPAPLILCGERLYLNRMWCNERTVA
CCCCCCHHHEEHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHCCHHHHH
RFFNEVNQAIAVDEDQLSRILDALFPPTDEVNWQKVAAAVALTRRISVISGGPGTGKTTT
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHEEEECCCCCCCHHH
VAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGAALRQLPLTDAQKKRIPEDASTL
HHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHH
HRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDSLPPHGRVIFLGDRDQ
HHHHCCCCCHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHCCCCCCEEEEEECCHH
LASVEAGAVLGDICAYVNAGFTAERARQLSRLTGSAIPAGAGTQAASLRDSLCLLQKSYR
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHC
FGSDSGIGKLAAAINCGDRSAIQAVFQQGFSDIEKRTLQSSDDYAGMLDEALAGYGRYLR
CCCCCCHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LLHEKATPEAILQAFNEYQLLCALREGPFGVRGLNDRIEQAMVQQRKIQRHPHSRWYEGR
HHHHCCCHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
PVMIARNDSALGLFNGDIGIALDRGQGLRVWFVMPDGTIKSVQPSRLPEHDTTWAMTVHK
EEEEEECCCEEEEEECCEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEC
SQGSEFDHAALILPSQRSPVVTRELVYTAVTRARRRLSLYADERILAGAIVTRTERRSGL
CCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHH
ATLFDEVSRTG
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3537961; 9278503; 3537960 [H]