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The map label for this gene is prgI

Identifier: 16766179

GI number: 16766179

Start: 3016075

End: 3016317

Strand: Reverse

Name: prgI

Synonym: STM2873

Alternate gene names: 16766179

Gene position: 3016317-3016075 (Counterclockwise)

Preceding gene: 16766180

Following gene: 16766178

Centisome position: 62.1

GC content: 46.09

Gene sequence:

>243_bases
ATGGCAACACCTTGGTCAGGCTATCTGGATGACGTCTCAGCAAAATTTGATACGGGCGTTGATAATCTACAAACGCAGGT
AACAGAGGCGCTGGATAAATTAGCAGCAAAACCCTCCGATCCGGCGCTACTGGCGGCGTATCAGAGTAAGCTCTCGGAAT
ATAACTTGTACCGTAACGCGCAATCGAACACGGTAAAAGTCTTTAAGGATATTGATGCTGCCATTATTCAGAACTTCCGT
TAA

Upstream 100 bases:

>100_bases
GCGCTCATTTCAGTACGGGGCGGAAGGTTATATCAAAATGAGCCCAGGCCATTGGTATTTCCCAAGCCCACTTTAATTTA
ACGTAAATAAGGAAGTCATT

Downstream 100 bases:

>100_bases
TCAGTTATAAGGTGGATTATGTCGATTGCAACTATTGTCCCTGAGAATGCCGTTATAGGGCAGGCGGTCAATATCAGGTC
TATGGAAACGGACATTGTCT

Product: needle complex major subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 80; Mature: 79

Protein sequence:

>80_residues
MATPWSGYLDDVSAKFDTGVDNLQTQVTEALDKLAAKPSDPALLAAYQSKLSEYNLYRNAQSNTVKVFKDIDAAIIQNFR

Sequences:

>Translated_80_residues
MATPWSGYLDDVSAKFDTGVDNLQTQVTEALDKLAAKPSDPALLAAYQSKLSEYNLYRNAQSNTVKVFKDIDAAIIQNFR
>Mature_79_residues
ATPWSGYLDDVSAKFDTGVDNLQTQVTEALDKLAAKPSDPALLAAYQSKLSEYNLYRNAQSNTVKVFKDIDAAIIQNFR

Specific function: Required for invasion of epithelial cells

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mxiH/prgI/yscF family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRGI_SALTY (P41784)

Other databases:

- EMBL:   U21676
- EMBL:   AE006468
- PIR:   S69784
- RefSeq:   NP_461794.1
- PDB:   2JOW
- PDB:   2KV7
- PDB:   2X9C
- PDBsum:   2JOW
- PDBsum:   2KV7
- PDBsum:   2X9C
- ProteinModelPortal:   P41784
- SMR:   P41784
- PRIDE:   P41784
- GeneID:   1254396
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM2873
- HOGENOM:   HBG637005
- OMA:   KDWTLSS
- ProtClustDB:   PRK15326
- BioCyc:   STYP99287:STM2873-MONOMER
- GO:   GO:0009405
- InterPro:   IPR021123
- InterPro:   IPR011841
- TIGRFAMs:   TIGR02105

Pfam domain/function: PF09392 MxiH

EC number: NA

Molecular weight: Translated: 8857; Mature: 8726

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATPWSGYLDDVSAKFDTGVDNLQTQVTEALDKLAAKPSDPALLAAYQSKLSEYNLYRNA
CCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCC
QSNTVKVFKDIDAAIIQNFR
CCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ATPWSGYLDDVSAKFDTGVDNLQTQVTEALDKLAAKPSDPALLAAYQSKLSEYNLYRNA
CCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCC
QSNTVKVFKDIDAAIIQNFR
CCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7476203; 11677609