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The map label for this gene is hilC [H]

Identifier: 16766173

GI number: 16766173

Start: 3012107

End: 3012994

Strand: Reverse

Name: hilC [H]

Synonym: STM2867

Alternate gene names: 16766173

Gene position: 3012994-3012107 (Counterclockwise)

Preceding gene: 16766174

Following gene: 16766172

Centisome position: 62.03

GC content: 37.05

Gene sequence:

>888_bases
ATGGTATTGCCTTCAATGAATAAATCAGTTGAGGCCATTAGCAATAATCACCTTCAACAGCCGAACAAATTTCCATTAAT
AAATGGATTAGCTGACGTAAGAGACTATTATGTCGCAAACTGCTTATTGTTTAAACTTAATAAAGGCAGTTTGCGAATTG
AAAACGAATTTGGGGAGTTCATCGAACGATCTGCGCCGTGTTTATTTTTATTGGAAAAAGATCAAACAATCACGCTTAGT
ATGAGCGAAATAGAAGGGCATATTGATTTTTCTTCACTGGAAGTTTCCTATGACTTAATGCAAAAATTCTACAAAGTTTT
TTACAGTACAAGAAACTATAATGATCGAGAGCTATCATTAAAAACGAAACCAAAGTATTTTTTTCATGCGGACTTGTTGC
CAGGGATGAGTGATACTTTTGACTCTATTTTGCATGGTGTGGCATGTCCACGGGTTTGTAGTAATGTGAGTATTGATGAT
CATGATTATTCATATTTCTCATTGATGTATCTTATATCGGCATTTGTACGTAAGCCCGGTGGGTTTGATTTCCTTGAGCG
AGCAATAAAAATTACGACAAAAGAGAAAGTTTATAACATTATTATCAGCGATCTCACCCGCAAATGGTCACAGGCTGAGG
TGGCAGGAAAGCTGTTTATGAGCGTATCAAGTCTGAAGCGAAAACTGGCCGCTGAAGAGGTGAGTTTTAGTAAAATATAC
CTGGATGCTCGTATGAATCAGGCTATAAAATTATTACGTATGGGGGCTGGAAATATTTCACAAGTCGCGACGATGTGTGG
CTATGATACGCCTTCTTATTTTATCGCTATTTTTAAACGGCATTTTAAGATTACACCGCTTAGCTTTATGCGTACAATGA
ACCATTGA

Upstream 100 bases:

>100_bases
AATAATAAAAAAATCGGATTTAAATCATCTCTGTGAGTTTTAATTATTTGTTTATAAGAATATAACGATTTTGAGTTCCT
TATAGCACACAGGATAAAAT

Downstream 100 bases:

>100_bases
TTTGTGAAATTATTTTAAACGTTACTATCTGTTTGCGTTACAGATACCAAATATTTTTTTAATCGTAGTGTATATTTCAG
TATCGCTACACCAGTGATAT

Product: invasion regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MVLPSMNKSVEAISNNHLQQPNKFPLINGLADVRDYYVANCLLFKLNKGSLRIENEFGEFIERSAPCLFLLEKDQTITLS
MSEIEGHIDFSSLEVSYDLMQKFYKVFYSTRNYNDRELSLKTKPKYFFHADLLPGMSDTFDSILHGVACPRVCSNVSIDD
HDYSYFSLMYLISAFVRKPGGFDFLERAIKITTKEKVYNIIISDLTRKWSQAEVAGKLFMSVSSLKRKLAAEEVSFSKIY
LDARMNQAIKLLRMGAGNISQVATMCGYDTPSYFIAIFKRHFKITPLSFMRTMNH

Sequences:

>Translated_295_residues
MVLPSMNKSVEAISNNHLQQPNKFPLINGLADVRDYYVANCLLFKLNKGSLRIENEFGEFIERSAPCLFLLEKDQTITLS
MSEIEGHIDFSSLEVSYDLMQKFYKVFYSTRNYNDRELSLKTKPKYFFHADLLPGMSDTFDSILHGVACPRVCSNVSIDD
HDYSYFSLMYLISAFVRKPGGFDFLERAIKITTKEKVYNIIISDLTRKWSQAEVAGKLFMSVSSLKRKLAAEEVSFSKIY
LDARMNQAIKLLRMGAGNISQVATMCGYDTPSYFIAIFKRHFKITPLSFMRTMNH
>Mature_295_residues
MVLPSMNKSVEAISNNHLQQPNKFPLINGLADVRDYYVANCLLFKLNKGSLRIENEFGEFIERSAPCLFLLEKDQTITLS
MSEIEGHIDFSSLEVSYDLMQKFYKVFYSTRNYNDRELSLKTKPKYFFHADLLPGMSDTFDSILHGVACPRVCSNVSIDD
HDYSYFSLMYLISAFVRKPGGFDFLERAIKITTKEKVYNIIISDLTRKWSQAEVAGKLFMSVSSLKRKLAAEEVSFSKIY
LDARMNQAIKLLRMGAGNISQVATMCGYDTPSYFIAIFKRHFKITPLSFMRTMNH

Specific function: Positive regulator of the expression of the invasion- associated type III secretion system encoded within SPI-1 (pathogenicity island 1) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790557, Length=123, Percent_Identity=36.5853658536585, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787776, Length=128, Percent_Identity=34.375, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1789933, Length=119, Percent_Identity=31.9327731092437, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1786778, Length=123, Percent_Identity=36.5853658536585, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1786758, Length=91, Percent_Identity=40.6593406593407, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1789932, Length=178, Percent_Identity=30.8988764044944, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786776, Length=91, Percent_Identity=37.3626373626374, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 33884; Mature: 33884

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLPSMNKSVEAISNNHLQQPNKFPLINGLADVRDYYVANCLLFKLNKGSLRIENEFGEF
CCCCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEECCCCEEEEHHHHHH
IERSAPCLFLLEKDQTITLSMSEIEGHIDFSSLEVSYDLMQKFYKVFYSTRNYNDRELSL
HHCCCCEEEEEECCCEEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
KTKPKYFFHADLLPGMSDTFDSILHGVACPRVCSNVSIDDHDYSYFSLMYLISAFVRKPG
EECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCC
GFDFLERAIKITTKEKVYNIIISDLTRKWSQAEVAGKLFMSVSSLKRKLAAEEVSFSKIY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
LDARMNQAIKLLRMGAGNISQVATMCGYDTPSYFIAIFKRHFKITPLSFMRTMNH
EHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHCC
>Mature Secondary Structure
MVLPSMNKSVEAISNNHLQQPNKFPLINGLADVRDYYVANCLLFKLNKGSLRIENEFGEF
CCCCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEEECCCCEEEEHHHHHH
IERSAPCLFLLEKDQTITLSMSEIEGHIDFSSLEVSYDLMQKFYKVFYSTRNYNDRELSL
HHCCCCEEEEEECCCEEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
KTKPKYFFHADLLPGMSDTFDSILHGVACPRVCSNVSIDDHDYSYFSLMYLISAFVRKPG
EECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCC
GFDFLERAIKITTKEKVYNIIISDLTRKWSQAEVAGKLFMSVSSLKRKLAAEEVSFSKIY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
LDARMNQAIKLLRMGAGNISQVATMCGYDTPSYFIAIFKRHFKITPLSFMRTMNH
EHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]