Click here to switch to the map view.

The map label for this gene is ybhO [H]

Identifier: 16764175

GI number: 16764175

Start: 877112

End: 878353

Strand: Reverse

Name: ybhO [H]

Synonym: STM0812

Alternate gene names: 16764175

Gene position: 878353-877112 (Counterclockwise)

Preceding gene: 16764176

Following gene: 16764174

Centisome position: 18.08

GC content: 54.35

Gene sequence:

>1242_bases
ATGAAATGCGGCTGGCGTGAAGGTAATCAAATTCAGCTACTGGAAAACGGCGACCAGTTCTATCCTGCCGTGTTTGAGGC
TATCGCTCAGGCACAGCAAAAAATCATTCTGGAAACCTTTATCTTGTTTGAAGATGAGGTGGGTAAAAAACTCCATACCG
CTCTGCTAAAAGCCGCACAGCGCGGCGTAAAAGCCGAAGTATTACTCGACGGCTACGGCTCTCCCGATCTCAGCGACGCG
TTTGTCGGCGAATTGACCTCAGCGGGCGTGATTTTTCGCTATTACGACCCCCGCCCGCGTCTACTGGGGTTGCGAACCAA
TATCTTCCGCCGAATGCACCGCAAAATTGTGGTGATTGATGATCGTATTGCCTTTGTCGGCGGCATTAACTACTCCGCCG
AACATATGTCGGATTACGGCCCGCAGGCGAAACAAGACTACGCGGTACGGGTCGAAGGGCCTGTAGTGGCCGATATCCTG
CAATTCGAAGTCGAGAATCTGCCGGGGCAAAGCCCCGCGCGCCGCTGGTGGAAGCGCCATCATCAGGCTGAAGAAAATCG
CCACCCCGGCGAAGCGCAGGCGCTGTTTGTCTGGCGGGATAATGAAGAACACCGCGACGATATCGAACGTCATTATCTGA
AAATGCTGACCCAGGCAAAGCGTGAAGTGATTATCGCTAACGCCTATTTTTTCCCCGGCTATCGCTTGCTCCACGCAATG
CGTAAAGCCGCCCGCCGTGGCGTGAGCGTAAAACTGATTGTCCAGGGGGAACCAGACATGCCGATAGTCAAAGTCGGCGC
GCGGTTGCTCTATAACTATCTGGTGAAGGGCGGTGTGCAGGTTTATGAATACCGACGACGTCCGCTGCATGGCAAAGTGG
CGCTGATGGACGATCACTGGGCCACGGTAGGGTCGAGTAATCTCGATCCGCTCAGCCTGTCGCTTAACCTTGAAGCTAAC
CTGATCATTCACGATCGTACTTTTAACCAGACCCTGCGCGATAACTTACAAGGCATCATCGTGAACGATTGTAAGCAGGT
CGATGAGTCTATGCTGCCGAAACGCACCTGGTGGAACCTGACCAAAAGCGTGCTGGCGTTCCACTTTTTACGTCATTTCC
CGGCGCTGGTCGGCTGGCTACCGGCGCATACCCCGCATCTGGCGCAGGTTCCCCCGCCTGCCCAGCCAGAAATGGAAACC
CAGGATCGCGTTGATCCAGAAAATACAGGAGTGAAGCCCTAA

Upstream 100 bases:

>100_bases
TTTACGTCAAGAATGCGAACGCCAGTTCTCCTACGGCGCTGCCGCTGCGGAACTGGCGACATTTATCAGACCATGCCCCC
CTTAGCGCGGAGATCCATCT

Downstream 100 bases:

>100_bases
TGGCTAAATCGCATCCGCGCTGGCGGCTGGCTAAAAAAGTGCTGACCTGGCTGTTTTTTATTGCGGTCGTCGTTCTGCTG
GTGGTTTATGCTAAAAAGGT

Product: cardiolipin synthase 2

Products: NA

Alternate protein names: CL synthase [H]

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MKCGWREGNQIQLLENGDQFYPAVFEAIAQAQQKIILETFILFEDEVGKKLHTALLKAAQRGVKAEVLLDGYGSPDLSDA
FVGELTSAGVIFRYYDPRPRLLGLRTNIFRRMHRKIVVIDDRIAFVGGINYSAEHMSDYGPQAKQDYAVRVEGPVVADIL
QFEVENLPGQSPARRWWKRHHQAEENRHPGEAQALFVWRDNEEHRDDIERHYLKMLTQAKREVIIANAYFFPGYRLLHAM
RKAARRGVSVKLIVQGEPDMPIVKVGARLLYNYLVKGGVQVYEYRRRPLHGKVALMDDHWATVGSSNLDPLSLSLNLEAN
LIIHDRTFNQTLRDNLQGIIVNDCKQVDESMLPKRTWWNLTKSVLAFHFLRHFPALVGWLPAHTPHLAQVPPPAQPEMET
QDRVDPENTGVKP

Sequences:

>Translated_413_residues
MKCGWREGNQIQLLENGDQFYPAVFEAIAQAQQKIILETFILFEDEVGKKLHTALLKAAQRGVKAEVLLDGYGSPDLSDA
FVGELTSAGVIFRYYDPRPRLLGLRTNIFRRMHRKIVVIDDRIAFVGGINYSAEHMSDYGPQAKQDYAVRVEGPVVADIL
QFEVENLPGQSPARRWWKRHHQAEENRHPGEAQALFVWRDNEEHRDDIERHYLKMLTQAKREVIIANAYFFPGYRLLHAM
RKAARRGVSVKLIVQGEPDMPIVKVGARLLYNYLVKGGVQVYEYRRRPLHGKVALMDDHWATVGSSNLDPLSLSLNLEAN
LIIHDRTFNQTLRDNLQGIIVNDCKQVDESMLPKRTWWNLTKSVLAFHFLRHFPALVGWLPAHTPHLAQVPPPAQPEMET
QDRVDPENTGVKP
>Mature_413_residues
MKCGWREGNQIQLLENGDQFYPAVFEAIAQAQQKIILETFILFEDEVGKKLHTALLKAAQRGVKAEVLLDGYGSPDLSDA
FVGELTSAGVIFRYYDPRPRLLGLRTNIFRRMHRKIVVIDDRIAFVGGINYSAEHMSDYGPQAKQDYAVRVEGPVVADIL
QFEVENLPGQSPARRWWKRHHQAEENRHPGEAQALFVWRDNEEHRDDIERHYLKMLTQAKREVIIANAYFFPGYRLLHAM
RKAARRGVSVKLIVQGEPDMPIVKVGARLLYNYLVKGGVQVYEYRRRPLHGKVALMDDHWATVGSSNLDPLSLSLNLEAN
LIIHDRTFNQTLRDNLQGIIVNDCKQVDESMLPKRTWWNLTKSVLAFHFLRHFPALVGWLPAHTPHLAQVPPPAQPEMET
QDRVDPENTGVKP

Specific function: Catalyzes, in vitro, the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol [H]

COG id: COG1502

COG function: function code I; Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PLD phosphodiesterase domains [H]

Homologues:

Organism=Escherichia coli, GI1787007, Length=413, Percent_Identity=86.4406779661017, Blast_Score=754, Evalue=0.0,
Organism=Escherichia coli, GI1787502, Length=391, Percent_Identity=26.5984654731458, Blast_Score=117, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001736 [H]

Pfam domain/function: PF00614 PLDc [H]

EC number: 2.7.8.-

Molecular weight: Translated: 47303; Mature: 47303

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: PS50035 PLD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCGWREGNQIQLLENGDQFYPAVFEAIAQAQQKIILETFILFEDEVGKKLHTALLKAAQ
CCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGVKAEVLLDGYGSPDLSDAFVGELTSAGVIFRYYDPRPRLLGLRTNIFRRMHRKIVVID
CCCEEEEEEECCCCCCCCHHHHHHHHCCCEEEEEECCCCCEEHHHHHHHHHHCCEEEEEE
DRIAFVGGINYSAEHMSDYGPQAKQDYAVRVEGPVVADILQFEVENLPGQSPARRWWKRH
CCEEEEECCCCCHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHH
HQAEENRHPGEAQALFVWRDNEEHRDDIERHYLKMLTQAKREVIIANAYFFPGYRLLHAM
HHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCEEEEEEEECCHHHHHHHH
RKAARRGVSVKLIVQGEPDMPIVKVGARLLYNYLVKGGVQVYEYRRRPLHGKVALMDDHW
HHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEEEECCCC
ATVGSSNLDPLSLSLNLEANLIIHDRTFNQTLRDNLQGIIVNDCKQVDESMLPKRTWWNL
CCCCCCCCCCEEEEEEEEEEEEEECCHHHHHHHHCCCEEEEHHHHHHHHHHCCCHHHHHH
TKSVLAFHFLRHFPALVGWLPAHTPHLAQVPPPAQPEMETQDRVDPENTGVKP
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCC
>Mature Secondary Structure
MKCGWREGNQIQLLENGDQFYPAVFEAIAQAQQKIILETFILFEDEVGKKLHTALLKAAQ
CCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGVKAEVLLDGYGSPDLSDAFVGELTSAGVIFRYYDPRPRLLGLRTNIFRRMHRKIVVID
CCCEEEEEEECCCCCCCCHHHHHHHHCCCEEEEEECCCCCEEHHHHHHHHHHCCEEEEEE
DRIAFVGGINYSAEHMSDYGPQAKQDYAVRVEGPVVADILQFEVENLPGQSPARRWWKRH
CCEEEEECCCCCHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHH
HQAEENRHPGEAQALFVWRDNEEHRDDIERHYLKMLTQAKREVIIANAYFFPGYRLLHAM
HHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCEEEEEEEECCHHHHHHHH
RKAARRGVSVKLIVQGEPDMPIVKVGARLLYNYLVKGGVQVYEYRRRPLHGKVALMDDHW
HHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEEEECCCC
ATVGSSNLDPLSLSLNLEANLIIHDRTFNQTLRDNLQGIIVNDCKQVDESMLPKRTWWNL
CCCCCCCCCCEEEEEEEEEEEEEECCHHHHHHHHCCCEEEEHHHHHHHHHHCCCHHHHHH
TKSVLAFHFLRHFPALVGWLPAHTPHLAQVPPPAQPEMETQDRVDPENTGVKP
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]