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The map label for this gene is ybgR [H]

Identifier: 16764123

GI number: 16764123

Start: 822017

End: 822955

Strand: Reverse

Name: ybgR [H]

Synonym: STM0758

Alternate gene names: 16764123

Gene position: 822955-822017 (Counterclockwise)

Preceding gene: 16764124

Following gene: 16764100

Centisome position: 16.94

GC content: 54.95

Gene sequence:

>939_bases
ATGGCGCACTCACACTCTCATGCCGATTCACACCTGCCGAAAGATAATAATGCTCGTCGCCTGCTTTTCGCCTTTATCGT
CACTGCCGGATTTATGCTCCTTGAGGTGGTGGGCGGGATACTCTCCGGCTCTCTGGCGTTGTTGGCGGATGCGGGACATA
TGCTCACCGACGCGGCGGCCCTTCTCTTTGCGCTGCTGGCGGTTCAATTTTCCCGTCGTCCCCCGACTGTTCGCCACACT
TTTGGCTGGCTAAGACTCACCACACTGGCGGCCTTTGTGAATGCCATTGCGTTGGTGGTCATTACCCTTCTCATTGTCTG
GGAAGCGATAGAGCGCTTTTACACGCCACGTCCGGTGGCGGGCAATCTGATGATGGTGATTGCGGTTGCGGGTCTGCTGG
CGAACCTGTTTGCGTTCTGGATTCTCCATCGGGGAAGCGATGAAAAAAACCTGAACGTGCGCGCTGCCGCGCTACATGTG
ATGGGCGATTTGCTGGGTTCCGTCGGCGCAATAGTCGCCGCGTTGATCATTATCTGGACAGGCTGGACGCCAGCGGACCC
GATTCTCTCTATTCTGGTTTCGGTACTGGTGCTACGCAGCGCCTGGCGTTTGTTAAAAGATAGCGTCAACGAATTGCTGG
AAGGCGCGCCGGTTTCACTGGATATTAATGCCTTACAGCGCCATTTAAGTCGGGAAATCCCCGAAGTCCGCAACGTACAC
CATGTGCATGTCTGGATGGTCGGCGAAAAACCGGTCATGACGTTGCACGCTCAGGTCATTCCGCCACACGACCATGATGC
GCTGCTGGAACGTATCCAGGATTTCCTGATGCACGAATACCATATTGCGCACGCTACGATTCAGATGGAGTATCAAGTGT
GTCACGGCCCGGACTGTCATCTGAATCAGACATCGTCCGGGCATGTTCATCACCATTAA

Upstream 100 bases:

>100_bases
AGTCTGATAACGGGAGAGCTTTCGCTCTCCTTTTTATTTTATCAGCGAAAAATCAGTATGATGTCTACAGTATTGATGAG
AATAACAAAGGAATGACGTT

Downstream 100 bases:

>100_bases
CGGGAAAGCGCGCGCGATCCTCGCTCCCGCGCGCTGTTTATCCACAGGCGGCTACCGTTCACGGCGATAAATGTCAGGAT
CAGATATTCCAGCGACATCG

Product: zinc transporter ZitB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MAHSHSHADSHLPKDNNARRLLFAFIVTAGFMLLEVVGGILSGSLALLADAGHMLTDAAALLFALLAVQFSRRPPTVRHT
FGWLRLTTLAAFVNAIALVVITLLIVWEAIERFYTPRPVAGNLMMVIAVAGLLANLFAFWILHRGSDEKNLNVRAAALHV
MGDLLGSVGAIVAALIIIWTGWTPADPILSILVSVLVLRSAWRLLKDSVNELLEGAPVSLDINALQRHLSREIPEVRNVH
HVHVWMVGEKPVMTLHAQVIPPHDHDALLERIQDFLMHEYHIAHATIQMEYQVCHGPDCHLNQTSSGHVHHH

Sequences:

>Translated_312_residues
MAHSHSHADSHLPKDNNARRLLFAFIVTAGFMLLEVVGGILSGSLALLADAGHMLTDAAALLFALLAVQFSRRPPTVRHT
FGWLRLTTLAAFVNAIALVVITLLIVWEAIERFYTPRPVAGNLMMVIAVAGLLANLFAFWILHRGSDEKNLNVRAAALHV
MGDLLGSVGAIVAALIIIWTGWTPADPILSILVSVLVLRSAWRLLKDSVNELLEGAPVSLDINALQRHLSREIPEVRNVH
HVHVWMVGEKPVMTLHAQVIPPHDHDALLERIQDFLMHEYHIAHATIQMEYQVCHGPDCHLNQTSSGHVHHH
>Mature_311_residues
AHSHSHADSHLPKDNNARRLLFAFIVTAGFMLLEVVGGILSGSLALLADAGHMLTDAAALLFALLAVQFSRRPPTVRHTF
GWLRLTTLAAFVNAIALVVITLLIVWEAIERFYTPRPVAGNLMMVIAVAGLLANLFAFWILHRGSDEKNLNVRAAALHVM
GDLLGSVGAIVAALIIIWTGWTPADPILSILVSVLVLRSAWRLLKDSVNELLEGAPVSLDINALQRHLSREIPEVRNVHH
VHVWMVGEKPVMTLHAQVIPPHDHDALLERIQDFLMHEYHIAHATIQMEYQVCHGPDCHLNQTSSGHVHHH

Specific function: Involved in zinc efflux across the cytoplasmic membrane, thus reducing zinc accumulation in the cytoplasm and rendering bacteria more resistant to zinc. It may contribute to zinc homeostasis at low concentrations of zinc [H]

COG id: COG1230

COG function: function code P; Co/Zn/Cd efflux system component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily [H]

Homologues:

Organism=Homo sapiens, GI52352805, Length=319, Percent_Identity=32.9153605015674, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI289803013, Length=316, Percent_Identity=32.2784810126582, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI289803009, Length=316, Percent_Identity=32.2784810126582, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI289803007, Length=316, Percent_Identity=32.2784810126582, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI289803003, Length=316, Percent_Identity=32.2784810126582, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI64762489, Length=316, Percent_Identity=32.2784810126582, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI21359890, Length=317, Percent_Identity=30.9148264984227, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI21361112, Length=308, Percent_Identity=31.4935064935065, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI20070323, Length=345, Percent_Identity=24.6376811594203, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI14210520, Length=230, Percent_Identity=29.1304347826087, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI52352803, Length=129, Percent_Identity=43.4108527131783, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI52351208, Length=162, Percent_Identity=30.2469135802469, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI222080086, Length=129, Percent_Identity=28.6821705426357, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI40255009, Length=129, Percent_Identity=28.6821705426357, Blast_Score=72, Evalue=6e-13,
Organism=Escherichia coli, GI1786966, Length=296, Percent_Identity=86.1486486486486, Blast_Score=466, Evalue=1e-133,
Organism=Escherichia coli, GI1790349, Length=191, Percent_Identity=27.2251308900524, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI193210990, Length=321, Percent_Identity=33.3333333333333, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17555794, Length=327, Percent_Identity=32.7217125382263, Blast_Score=155, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17555796, Length=325, Percent_Identity=31.6923076923077, Blast_Score=147, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI32564488, Length=317, Percent_Identity=30.2839116719243, Blast_Score=140, Evalue=9e-34,
Organism=Caenorhabditis elegans, GI17550440, Length=126, Percent_Identity=34.9206349206349, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17550442, Length=126, Percent_Identity=34.9206349206349, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6320411, Length=181, Percent_Identity=36.4640883977901, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6323899, Length=131, Percent_Identity=37.4045801526718, Blast_Score=89, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6324892, Length=121, Percent_Identity=38.0165289256198, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24656728, Length=346, Percent_Identity=30.0578034682081, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24656724, Length=346, Percent_Identity=30.0578034682081, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24656720, Length=346, Percent_Identity=30.0578034682081, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24656715, Length=346, Percent_Identity=30.0578034682081, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI21357035, Length=346, Percent_Identity=30.0578034682081, Blast_Score=132, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24583858, Length=317, Percent_Identity=29.3375394321767, Blast_Score=118, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24584409, Length=136, Percent_Identity=36.7647058823529, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI28574430, Length=136, Percent_Identity=36.7647058823529, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24585900, Length=147, Percent_Identity=32.6530612244898, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24585898, Length=147, Percent_Identity=32.6530612244898, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24585896, Length=147, Percent_Identity=32.6530612244898, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI19921672, Length=147, Percent_Identity=32.6530612244898, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24645863, Length=127, Percent_Identity=32.2834645669291, Blast_Score=75, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002524 [H]

Pfam domain/function: PF01545 Cation_efflux [H]

EC number: NA

Molecular weight: Translated: 34462; Mature: 34331

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: PS00511 CRF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHSHSHADSHLPKDNNARRLLFAFIVTAGFMLLEVVGGILSGSLALLADAGHMLTDAAA
CCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHH
LLFALLAVQFSRRPPTVRHTFGWLRLTTLAAFVNAIALVVITLLIVWEAIERFYTPRPVA
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GNLMMVIAVAGLLANLFAFWILHRGSDEKNLNVRAAALHVMGDLLGSVGAIVAALIIIWT
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GWTPADPILSILVSVLVLRSAWRLLKDSVNELLEGAPVSLDINALQRHLSREIPEVRNVH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCHHHHCCE
HVHVWMVGEKPVMTLHAQVIPPHDHDALLERIQDFLMHEYHIAHATIQMEYQVCHGPDCH
EEEEEEECCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCC
LNQTSSGHVHHH
CCCCCCCCCCCC
>Mature Secondary Structure 
AHSHSHADSHLPKDNNARRLLFAFIVTAGFMLLEVVGGILSGSLALLADAGHMLTDAAA
CCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHH
LLFALLAVQFSRRPPTVRHTFGWLRLTTLAAFVNAIALVVITLLIVWEAIERFYTPRPVA
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GNLMMVIAVAGLLANLFAFWILHRGSDEKNLNVRAAALHVMGDLLGSVGAIVAALIIIWT
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GWTPADPILSILVSVLVLRSAWRLLKDSVNELLEGAPVSLDINALQRHLSREIPEVRNVH
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCHHHHCCE
HVHVWMVGEKPVMTLHAQVIPPHDHDALLERIQDFLMHEYHIAHATIQMEYQVCHGPDCH
EEEEEEECCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCC
LNQTSSGHVHHH
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]