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The map label for this gene is speF [H]

Identifier: 16764071

GI number: 16764071

Start: 763379

End: 765577

Strand: Reverse

Name: speF [H]

Synonym: STM0701

Alternate gene names: 16764071

Gene position: 765577-763379 (Counterclockwise)

Preceding gene: 16764072

Following gene: 16764070

Centisome position: 15.76

GC content: 53.89

Gene sequence:

>2199_bases
ATGTCAGAATTAAAAATTGCCGTTAGCCGTCATTGCCCGGATTGTTTTTCTACACACCGTAATATTGTAAATGTTGATGA
GAGTCGTTTCATCGACGTGGCTGCCATCGTGTTATCCATTGACGACATTGAACACGGAAAACTCGATGAAATCGACGCAA
CGGGTTACGGTATTCCCGTGTTTGTCGCGACACATGACGAAGGGCGCGTACCGCCTGAGTATTTGCCGCGTATCTCTGGT
GTATTCGAATATAATGAATCCCGTACTGCCTTCTATGGTCGCCAGTTGGAAACCGCAGCAAGCCACTACGAAACGCAGTT
ACGTCCGCCGTTTTTCCGCGCGCTGGTGGATTATGTCAACCAGGGCAACAGCGCATTTGACTGCCCGGGGCATCAGGGCG
GCGAATTCTTCCGCCGTCATCCTGCCGGTAATCAGTTCGTGGAATACTTTGGCGAAACGCTCTTCCGCTCCGACCTATGC
AACGCGGACGTGGCGATGGGCGATCTGCTGATTCACGAAGGCGCGCCTTGCATTGCGCAGCAACATGCGGCGAAAGTCTT
TAACGCCGATAAGACCTACTTTGTGCTGAACGGGACCTCCTCCTCTAACAAAGTCGTACTCAACGCGCTGTTAACGCCGG
GCGATCTGGTACTGTTTGACCGTAACAACCACAAATCTAACCACCACGGCGCATTATTGCAGGCGGGCGCAACGCCAGTT
TATCTGGAAACCGCGCGTAACCCGTATGGTTTTATCGGCGGGATCGACGCTCACTGCTTCGAAGAAGATTACCTGCGCGA
GCTGATTAGCGAAGTCGCGCCGCAGCGTGCCCGCGAAGCACGTCCATTCCGTCTGGCCGTCATCCAGTTAGGCACCTACG
ACGGTACCATTTATAACGCCCGTCAGGTCGTCGATAAAATTGGTCATCTGTGCGACTACATCCTGTTTGACTCCGCCTGG
GTCGGCTATGAACAATTTATTCCGATGATGGCCGATTGTTCGCCGCTGCTGCTGGAACTGAACGAAAACGATCCGGGTAT
TCTGGTGACGCAGTCCGTTCACAAACAACAAGCCGGTTTCTCCCAGACCTCGCAGATCCATAAAAAAGATAGCCATATCA
AAGGGCAATCGCGCTACGTTCCGCATAAGCGCATGAACAACGCCTTTATGATGCACGCCTCCACCAGCCCGTTCTATCCG
CTGTTCGCCGCGCTGGACGTTAACGCCAAAATGCACGAAGGCGTCAGCGGTCGCAATATGTGGATGGATTGCGTGGTTAA
CGGCATCGATGCCCGTAAATTGATCCTCGAAAACTGTCATCACATCCGTCCGTTCGTACCGGAACTGATTGATGGTAAGC
CGTGGCAGTCATACCCGACGTCAGAGATCGCCAGCGATCTGCGCTTCTTCCACTTCGTTCCGGGAGAACACTGGCATGCG
TTTGAAGGCTATGCCGAACATCAGTACTTTGTCGACCCTTGCAAACTGCTGCTCACCACACCGGGCATTAATGCAGCGAG
CGGCGAATATGAAGACTTTGGCGTTCCTGCCACGATCCTCGCCAACTTCCTGCGCGAGAACGGCGTTGTGCCGGAAAAAT
GCGACCTCAACTCCATTCTGTTCCTGCTGACGCCGGCAGAAGACATGGCGAAGTTACAACAGCTTGTCGCCCTGCTGGCT
CGTTTCGAAAAACTGCTGGAAGCTGATGCGCCGTTAGCGGAAGTATTACCGTCCATCTACAAACAGCATGAAGCGCGTTA
TGCCGGCTATACCCTGCGTCAGCTTTGCCAGGAGATGCACGATCTCTATGCGCGGCACAACGTGAAACAGCTGCAAAAAG
AGATGTTCCGTAAATCGCATTTCCCGAAAGTCAGTATGAATCCGCAAGAGGCCAACTATGCCTATCTGCGCGGCGAGGTC
GAACTGGTTCGCCTGCCGGAAGCGGAAGGTCGTATCGCGGCTGAAGGCGCTCTGCCTTACCCGCCGGGAGTGCTGTGTGT
AGTTCCGGGTGAAATCTGGGGCGGTTCTGTCCTGCGTTACTTCAGCGCCCTGGAAGAAGGGATCAACCTGCTGCCGGGCT
TTGCGCCTGAACTGCAGGGCGTTTATATCGAAGAACACGACGGCCGTAAGCAGGTCTGGTGCTACGTCATTAAACCTCGT
GACGCACAGCGCTCCCTGCTGAAGGAGGAAAAATTATGA

Upstream 100 bases:

>100_bases
ATTTTTTTATCAGCGGGATAGCTTTGATTTTTTCCGGAAGAATCAGTTTCTCATGCGAGAAATTGAGGGCCTGCTATTAC
CTGAAATAAAGAGATGAAAA

Downstream 100 bases:

>100_bases
GTAAACCTAAATCCAATAAAATGGGTGTCGTGCAGCTCACAATTCTGACTATGGTCAACATGATGGGCTCCGGGATCATC
ATGCTACCGACCAAACTGTC

Product: ornithine decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 732; Mature: 731

Protein sequence:

>732_residues
MSELKIAVSRHCPDCFSTHRNIVNVDESRFIDVAAIVLSIDDIEHGKLDEIDATGYGIPVFVATHDEGRVPPEYLPRISG
VFEYNESRTAFYGRQLETAASHYETQLRPPFFRALVDYVNQGNSAFDCPGHQGGEFFRRHPAGNQFVEYFGETLFRSDLC
NADVAMGDLLIHEGAPCIAQQHAAKVFNADKTYFVLNGTSSSNKVVLNALLTPGDLVLFDRNNHKSNHHGALLQAGATPV
YLETARNPYGFIGGIDAHCFEEDYLRELISEVAPQRAREARPFRLAVIQLGTYDGTIYNARQVVDKIGHLCDYILFDSAW
VGYEQFIPMMADCSPLLLELNENDPGILVTQSVHKQQAGFSQTSQIHKKDSHIKGQSRYVPHKRMNNAFMMHASTSPFYP
LFAALDVNAKMHEGVSGRNMWMDCVVNGIDARKLILENCHHIRPFVPELIDGKPWQSYPTSEIASDLRFFHFVPGEHWHA
FEGYAEHQYFVDPCKLLLTTPGINAASGEYEDFGVPATILANFLRENGVVPEKCDLNSILFLLTPAEDMAKLQQLVALLA
RFEKLLEADAPLAEVLPSIYKQHEARYAGYTLRQLCQEMHDLYARHNVKQLQKEMFRKSHFPKVSMNPQEANYAYLRGEV
ELVRLPEAEGRIAAEGALPYPPGVLCVVPGEIWGGSVLRYFSALEEGINLLPGFAPELQGVYIEEHDGRKQVWCYVIKPR
DAQRSLLKEEKL

Sequences:

>Translated_732_residues
MSELKIAVSRHCPDCFSTHRNIVNVDESRFIDVAAIVLSIDDIEHGKLDEIDATGYGIPVFVATHDEGRVPPEYLPRISG
VFEYNESRTAFYGRQLETAASHYETQLRPPFFRALVDYVNQGNSAFDCPGHQGGEFFRRHPAGNQFVEYFGETLFRSDLC
NADVAMGDLLIHEGAPCIAQQHAAKVFNADKTYFVLNGTSSSNKVVLNALLTPGDLVLFDRNNHKSNHHGALLQAGATPV
YLETARNPYGFIGGIDAHCFEEDYLRELISEVAPQRAREARPFRLAVIQLGTYDGTIYNARQVVDKIGHLCDYILFDSAW
VGYEQFIPMMADCSPLLLELNENDPGILVTQSVHKQQAGFSQTSQIHKKDSHIKGQSRYVPHKRMNNAFMMHASTSPFYP
LFAALDVNAKMHEGVSGRNMWMDCVVNGIDARKLILENCHHIRPFVPELIDGKPWQSYPTSEIASDLRFFHFVPGEHWHA
FEGYAEHQYFVDPCKLLLTTPGINAASGEYEDFGVPATILANFLRENGVVPEKCDLNSILFLLTPAEDMAKLQQLVALLA
RFEKLLEADAPLAEVLPSIYKQHEARYAGYTLRQLCQEMHDLYARHNVKQLQKEMFRKSHFPKVSMNPQEANYAYLRGEV
ELVRLPEAEGRIAAEGALPYPPGVLCVVPGEIWGGSVLRYFSALEEGINLLPGFAPELQGVYIEEHDGRKQVWCYVIKPR
DAQRSLLKEEKL
>Mature_731_residues
SELKIAVSRHCPDCFSTHRNIVNVDESRFIDVAAIVLSIDDIEHGKLDEIDATGYGIPVFVATHDEGRVPPEYLPRISGV
FEYNESRTAFYGRQLETAASHYETQLRPPFFRALVDYVNQGNSAFDCPGHQGGEFFRRHPAGNQFVEYFGETLFRSDLCN
ADVAMGDLLIHEGAPCIAQQHAAKVFNADKTYFVLNGTSSSNKVVLNALLTPGDLVLFDRNNHKSNHHGALLQAGATPVY
LETARNPYGFIGGIDAHCFEEDYLRELISEVAPQRAREARPFRLAVIQLGTYDGTIYNARQVVDKIGHLCDYILFDSAWV
GYEQFIPMMADCSPLLLELNENDPGILVTQSVHKQQAGFSQTSQIHKKDSHIKGQSRYVPHKRMNNAFMMHASTSPFYPL
FAALDVNAKMHEGVSGRNMWMDCVVNGIDARKLILENCHHIRPFVPELIDGKPWQSYPTSEIASDLRFFHFVPGEHWHAF
EGYAEHQYFVDPCKLLLTTPGINAASGEYEDFGVPATILANFLRENGVVPEKCDLNSILFLLTPAEDMAKLQQLVALLAR
FEKLLEADAPLAEVLPSIYKQHEARYAGYTLRQLCQEMHDLYARHNVKQLQKEMFRKSHFPKVSMNPQEANYAYLRGEVE
LVRLPEAEGRIAAEGALPYPPGVLCVVPGEIWGGSVLRYFSALEEGINLLPGFAPELQGVYIEEHDGRKQVWCYVIKPRD
AQRSLLKEEKL

Specific function: Spermidine biosynthesis from ornithine. [C]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1786909, Length=732, Percent_Identity=91.6666666666667, Blast_Score=1414, Evalue=0.0,
Organism=Escherichia coli, GI87082193, Length=719, Percent_Identity=67.7329624478442, Blast_Score=1022, Evalue=0.0,
Organism=Escherichia coli, GI221142684, Length=647, Percent_Identity=32.7666151468315, Blast_Score=340, Evalue=2e-94,
Organism=Escherichia coli, GI1790573, Length=641, Percent_Identity=33.5413416536661, Blast_Score=310, Evalue=2e-85,
Organism=Escherichia coli, GI1786384, Length=700, Percent_Identity=30.7142857142857, Blast_Score=299, Evalue=5e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR005308
- InterPro:   IPR011193
- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C; PF03709 OKR_DC_1_N [H]

EC number: =4.1.1.17 [H]

Molecular weight: Translated: 82451; Mature: 82319

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELKIAVSRHCPDCFSTHRNIVNVDESRFIDVAAIVLSIDDIEHGKLDEIDATGYGIPV
CCCCEEHHHHCCCHHHHHCCCEEECCHHHHHHHEEEEEEECCCCCCCCCCCCCCCCCCEE
FVATHDEGRVPPEYLPRISGVFEYNESRTAFYGRQLETAASHYETQLRPPFFRALVDYVN
EEEECCCCCCCHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
QGNSAFDCPGHQGGEFFRRHPAGNQFVEYFGETLFRSDLCNADVAMGDLLIHEGAPCIAQ
CCCCEECCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHEECCCCHHHH
QHAAKVFNADKTYFVLNGTSSSNKVVLNALLTPGDLVLFDRNNHKSNHHGALLQAGATPV
HHHHHHHCCCCEEEEEECCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCEEECCCCEE
YLETARNPYGFIGGIDAHCFEEDYLRELISEVAPQRAREARPFRLAVIQLGTYDGTIYNA
EEECCCCCCCEECCCCHHHCCHHHHHHHHHHHCHHHHHCCCCEEEEEEEEECCCCCCHHH
RQVVDKIGHLCDYILFDSAWVGYEQFIPMMADCSPLLLELNENDPGILVTQSVHKQQAGF
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEECCCCCCEEEEHHHHHHHCCC
SQTSQIHKKDSHIKGQSRYVPHKRMNNAFMMHASTSPFYPLFAALDVNAKMHEGVSGRNM
HHHHHHHHHHCCCCCCCCCCCHHHCCCEEEEEECCCCCCCEEEEEECCCHHHCCCCCCCH
WMDCVVNGIDARKLILENCHHIRPFVPELIDGKPWQSYPTSEIASDLRFFHFVPGEHWHA
HHHHHHCCCCHHHHHHHHHHHCCCCHHHHHCCCCCCCCCHHHHHHHHHEEEECCCCCCCC
FEGYAEHQYFVDPCKLLLTTPGINAASGEYEDFGVPATILANFLRENGVVPEKCDLNSIL
CCCCCCCCEECCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEE
FLLTPAEDMAKLQQLVALLARFEKLLEADAPLAEVLPSIYKQHEARYAGYTLRQLCQEMH
EEEECHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
DLYARHNVKQLQKEMFRKSHFPKVSMNPQEANYAYLRGEVELVRLPEAEGRIAAEGALPY
HHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCEEEEECCCCCCCEEECCCCCC
PPGVLCVVPGEIWGGSVLRYFSALEEGINLLPGFAPELQGVYIEEHDGRKQVWCYVIKPR
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCEEEEEEEECCC
DAQRSLLKEEKL
HHHHHHHHHCCC
>Mature Secondary Structure 
SELKIAVSRHCPDCFSTHRNIVNVDESRFIDVAAIVLSIDDIEHGKLDEIDATGYGIPV
CCCEEHHHHCCCHHHHHCCCEEECCHHHHHHHEEEEEEECCCCCCCCCCCCCCCCCCEE
FVATHDEGRVPPEYLPRISGVFEYNESRTAFYGRQLETAASHYETQLRPPFFRALVDYVN
EEEECCCCCCCHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
QGNSAFDCPGHQGGEFFRRHPAGNQFVEYFGETLFRSDLCNADVAMGDLLIHEGAPCIAQ
CCCCEECCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHEECCCCHHHH
QHAAKVFNADKTYFVLNGTSSSNKVVLNALLTPGDLVLFDRNNHKSNHHGALLQAGATPV
HHHHHHHCCCCEEEEEECCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCEEECCCCEE
YLETARNPYGFIGGIDAHCFEEDYLRELISEVAPQRAREARPFRLAVIQLGTYDGTIYNA
EEECCCCCCCEECCCCHHHCCHHHHHHHHHHHCHHHHHCCCCEEEEEEEEECCCCCCHHH
RQVVDKIGHLCDYILFDSAWVGYEQFIPMMADCSPLLLELNENDPGILVTQSVHKQQAGF
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEECCCCCCEEEEHHHHHHHCCC
SQTSQIHKKDSHIKGQSRYVPHKRMNNAFMMHASTSPFYPLFAALDVNAKMHEGVSGRNM
HHHHHHHHHHCCCCCCCCCCCHHHCCCEEEEEECCCCCCCEEEEEECCCHHHCCCCCCCH
WMDCVVNGIDARKLILENCHHIRPFVPELIDGKPWQSYPTSEIASDLRFFHFVPGEHWHA
HHHHHHCCCCHHHHHHHHHHHCCCCHHHHHCCCCCCCCCHHHHHHHHHEEEECCCCCCCC
FEGYAEHQYFVDPCKLLLTTPGINAASGEYEDFGVPATILANFLRENGVVPEKCDLNSIL
CCCCCCCCEECCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEE
FLLTPAEDMAKLQQLVALLARFEKLLEADAPLAEVLPSIYKQHEARYAGYTLRQLCQEMH
EEEECHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
DLYARHNVKQLQKEMFRKSHFPKVSMNPQEANYAYLRGEVELVRLPEAEGRIAAEGALPY
HHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCEEEEECCCCCCCEEECCCCCC
PPGVLCVVPGEIWGGSVLRYFSALEEGINLLPGFAPELQGVYIEEHDGRKQVWCYVIKPR
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCEEEEEEEECCC
DAQRSLLKEEKL
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1939141; 8905232; 9278503 [H]