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The map label for this gene is lnt [H]

Identifier: 16764043

GI number: 16764043

Start: 730172

End: 731710

Strand: Reverse

Name: lnt [H]

Synonym: STM0666

Alternate gene names: 16764043

Gene position: 731710-730172 (Counterclockwise)

Preceding gene: 16764044

Following gene: 16764042

Centisome position: 15.06

GC content: 54.91

Gene sequence:

>1539_bases
ATGGCATTTGCCTCGTTAATTGAACGCCAGCGTATTCGCCTGCTGCTGGCGTTATTATTCGGCGCCTGCGGAACACTGGC
TTTCTCTCCGTATGACGTCTGGCCCGCAGCGATAGTGTCGCTTATCGGGCTGCAGGCCTTAACGTTTAATCGCCGCCCGC
TCCAGTCTGCCGCCATCGGCTATTGCTGGGGACTCGGACTTTTCGGTAGCGGGATTAACTGGGTTTATGTCAGTATCGCG
CAGTTTGGCGGCATGCCGGGCCCGGTTAACGTTTTTCTGGTGGTGCTGCTTGCAGCTTATCTCTCGCTGTATACCGGACT
GTTTGCCGGGATTTTGTCGCGCCTGTGGCCAAAAACCAACTGGCTGCGCGTCGCTATCGCCGCGCCTGCAATATGGCAAA
TCACCGAATTTTTACGCGGCTGGGTGCTGACCGGCTTCCCCTGGCTGCAATTTGGCTATAGTCAGGTCGATGGCCCGCTA
AAAGGCCTGGCGCCGGTAATGGGCGTCGAAGCGATCAACTTCCTGCTGATGATGGTCAGCGGCCTGTTAGCGCTGGCACT
GGCGACGCGGAACTGGCGTCCGCTGGCTGTCGCCGTGATTCTGTTTGCTTTGCCCTTTCCGCTACGTTATATCCAGTGGT
TTACGCTGGAACCGGCCAAAGCGACCCAGGTATCGCTGGTGCAGGGCGATATCCCGCAGTCGCTGAAGTGGGACGAAAAC
CAGCTACTGAATACGCTAAAAATTTATCTCAACGAAACTCGCCCAGAGTTAGGCAAATCACAGATTATTATCTGGCCTGA
GTCGGCGATTCCGGATCTCGAAATCAATCAGCAGCCCTTCCTTCGTTCGCTGGACGAGATGTTACGCGAAAAAAATAGCA
CGCTGATCACCGGTATTGTCGATGCGCGTCTCAATAAACAGAATCGATACGACACCTACAATACGATTATTACGTTGGGC
AAGGATAATCCATACAGTTATGACTCGCCCAATCGCTACAATAAAAATCACCTTGTGCCCTTTGGCGAGTTCGTTCCGCT
GGAGTCTATCCTGCGTCCGCTGGCGCCGTTCTTCGATCTGCCCATGTCCTCCTTTAGCCGCGGCCCTTATATCCAGCCGC
AGTTACATGCGCACGACTATAAGCTGACGGCGGCAATCTGCTATGAAATTATTCTTGGCGAACAGGTGCGGGATAACTTC
CGCCCGGACACCGACTATCTGCTGACGATTTCTAACGACGCCTGGTTTGGTAAGTCCATTGGCCCGTGGCAACATTTCCA
GATGGCGCGGATGCGTTCGCTGGAGCTGGCGCGTCCGTTGCTGCGCAGTACTAATAACGGTATTACGGCGGTGATTGGCC
CTCAGGGCGAGATTCAGGCGATGATCCCGCAGTTCACACGCCAGGTACTGACCACCAATGTCACGCCAACCACGGGGTTA
ACTCCCTATGCCCGTACCGGCAACTGGCCGCTATGGGTACTGACCGCGCTGTTTGCTTTTGGCGCGGTAGTGATGAGTCT
GCGACAACGACGGAAATAA

Upstream 100 bases:

>100_bases
GCGATGGCCGATAGTCGTCGTATTATTCAGGTGCATGTCAGGATCCCGGATGACTCGCCCCAGCCAAAACTGGACGAATA
ACAGCAATAGTGGACTAAAA

Downstream 100 bases:

>100_bases
TCTCTCCCCAGGCCGGATAGCGCTTCATTTATCCGGCCTGAAAATCCTCCTTTTTCCCCCATTCTGGCACGTCTATTGCT
TTGTTAAACATGGCAAACCT

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase; Copper homeostasis protein CutE [H]

Number of amino acids: Translated: 512; Mature: 511

Protein sequence:

>512_residues
MAFASLIERQRIRLLLALLFGACGTLAFSPYDVWPAAIVSLIGLQALTFNRRPLQSAAIGYCWGLGLFGSGINWVYVSIA
QFGGMPGPVNVFLVVLLAAYLSLYTGLFAGILSRLWPKTNWLRVAIAAPAIWQITEFLRGWVLTGFPWLQFGYSQVDGPL
KGLAPVMGVEAINFLLMMVSGLLALALATRNWRPLAVAVILFALPFPLRYIQWFTLEPAKATQVSLVQGDIPQSLKWDEN
QLLNTLKIYLNETRPELGKSQIIIWPESAIPDLEINQQPFLRSLDEMLREKNSTLITGIVDARLNKQNRYDTYNTIITLG
KDNPYSYDSPNRYNKNHLVPFGEFVPLESILRPLAPFFDLPMSSFSRGPYIQPQLHAHDYKLTAAICYEIILGEQVRDNF
RPDTDYLLTISNDAWFGKSIGPWQHFQMARMRSLELARPLLRSTNNGITAVIGPQGEIQAMIPQFTRQVLTTNVTPTTGL
TPYARTGNWPLWVLTALFAFGAVVMSLRQRRK

Sequences:

>Translated_512_residues
MAFASLIERQRIRLLLALLFGACGTLAFSPYDVWPAAIVSLIGLQALTFNRRPLQSAAIGYCWGLGLFGSGINWVYVSIA
QFGGMPGPVNVFLVVLLAAYLSLYTGLFAGILSRLWPKTNWLRVAIAAPAIWQITEFLRGWVLTGFPWLQFGYSQVDGPL
KGLAPVMGVEAINFLLMMVSGLLALALATRNWRPLAVAVILFALPFPLRYIQWFTLEPAKATQVSLVQGDIPQSLKWDEN
QLLNTLKIYLNETRPELGKSQIIIWPESAIPDLEINQQPFLRSLDEMLREKNSTLITGIVDARLNKQNRYDTYNTIITLG
KDNPYSYDSPNRYNKNHLVPFGEFVPLESILRPLAPFFDLPMSSFSRGPYIQPQLHAHDYKLTAAICYEIILGEQVRDNF
RPDTDYLLTISNDAWFGKSIGPWQHFQMARMRSLELARPLLRSTNNGITAVIGPQGEIQAMIPQFTRQVLTTNVTPTTGL
TPYARTGNWPLWVLTALFAFGAVVMSLRQRRK
>Mature_511_residues
AFASLIERQRIRLLLALLFGACGTLAFSPYDVWPAAIVSLIGLQALTFNRRPLQSAAIGYCWGLGLFGSGINWVYVSIAQ
FGGMPGPVNVFLVVLLAAYLSLYTGLFAGILSRLWPKTNWLRVAIAAPAIWQITEFLRGWVLTGFPWLQFGYSQVDGPLK
GLAPVMGVEAINFLLMMVSGLLALALATRNWRPLAVAVILFALPFPLRYIQWFTLEPAKATQVSLVQGDIPQSLKWDENQ
LLNTLKIYLNETRPELGKSQIIIWPESAIPDLEINQQPFLRSLDEMLREKNSTLITGIVDARLNKQNRYDTYNTIITLGK
DNPYSYDSPNRYNKNHLVPFGEFVPLESILRPLAPFFDLPMSSFSRGPYIQPQLHAHDYKLTAAICYEIILGEQVRDNFR
PDTDYLLTISNDAWFGKSIGPWQHFQMARMRSLELARPLLRSTNNGITAVIGPQGEIQAMIPQFTRQVLTTNVTPTTGLT
PYARTGNWPLWVLTALFAFGAVVMSLRQRRK

Specific function: Transfers the fatty acyl group on membrane lipoproteins [H]

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1786878, Length=512, Percent_Identity=89.2578125, Blast_Score=941, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004563
- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 2.3.1.- [C]

Molecular weight: Translated: 57599; Mature: 57468

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFASLIERQRIRLLLALLFGACGTLAFSPYDVWPAAIVSLIGLQALTFNRRPLQSAAIG
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
YCWGLGLFGSGINWVYVSIAQFGGMPGPVNVFLVVLLAAYLSLYTGLFAGILSRLWPKTN
HHHHHHHHCCCCHHEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
WLRVAIAAPAIWQITEFLRGWVLTGFPWLQFGYSQVDGPLKGLAPVMGVEAINFLLMMVS
EEEEEEECCHHHHHHHHHHHHHHCCCHHHHHCHHHCCCCHHHHHHHHHHHHHHHHHHHHH
GLLALALATRNWRPLAVAVILFALPFPLRYIQWFTLEPAKATQVSLVQGDIPQSLKWDEN
HHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHEEEECCCCCCCEEEEEECCCCCCCCCCHH
QLLNTLKIYLNETRPELGKSQIIIWPESAIPDLEINQQPFLRSLDEMLREKNSTLITGIV
HHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEH
DARLNKQNRYDTYNTIITLGKDNPYSYDSPNRYNKNHLVPFGEFVPLESILRPLAPFFDL
HHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
PMSSFSRGPYIQPQLHAHDYKLTAAICYEIILGEQVRDNFRPDTDYLLTISNDAWFGKSI
CHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCC
GPWQHFQMARMRSLELARPLLRSTNNGITAVIGPQGEIQAMIPQFTRQVLTTNVTPTTGL
CCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCC
TPYARTGNWPLWVLTALFAFGAVVMSLRQRRK
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AFASLIERQRIRLLLALLFGACGTLAFSPYDVWPAAIVSLIGLQALTFNRRPLQSAAIG
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
YCWGLGLFGSGINWVYVSIAQFGGMPGPVNVFLVVLLAAYLSLYTGLFAGILSRLWPKTN
HHHHHHHHCCCCHHEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
WLRVAIAAPAIWQITEFLRGWVLTGFPWLQFGYSQVDGPLKGLAPVMGVEAINFLLMMVS
EEEEEEECCHHHHHHHHHHHHHHCCCHHHHHCHHHCCCCHHHHHHHHHHHHHHHHHHHHH
GLLALALATRNWRPLAVAVILFALPFPLRYIQWFTLEPAKATQVSLVQGDIPQSLKWDEN
HHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHEEEECCCCCCCEEEEEECCCCCCCCCCHH
QLLNTLKIYLNETRPELGKSQIIIWPESAIPDLEINQQPFLRSLDEMLREKNSTLITGIV
HHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEH
DARLNKQNRYDTYNTIITLGKDNPYSYDSPNRYNKNHLVPFGEFVPLESILRPLAPFFDL
HHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
PMSSFSRGPYIQPQLHAHDYKLTAAICYEIILGEQVRDNFRPDTDYLLTISNDAWFGKSI
CHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCC
GPWQHFQMARMRSLELARPLLRSTNNGITAVIGPQGEIQAMIPQFTRQVLTTNVTPTTGL
CCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCC
TPYARTGNWPLWVLTALFAFGAVVMSLRQRRK
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]