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The map label for this gene is citC [H]

Identifier: 16764001

GI number: 16764001

Start: 686566

End: 687642

Strand: Reverse

Name: citC [H]

Synonym: STM0624

Alternate gene names: 16764001

Gene position: 687642-686566 (Counterclockwise)

Preceding gene: 16764004

Following gene: 16764000

Centisome position: 14.16

GC content: 51.62

Gene sequence:

>1077_bases
ATGTTTGGCAATAATGTATTCACTCGGGTAAAACGCTCTGAAAATAAAAAAATGGCGGAGATCGCTCACTTTCTCAAAGA
GAATGATTTAAGCGTCGATACCACTGTAGAAGTGTTTATTACCGTCAGCCGTGATGACCGTCTTATTGCCTGCGGCGGTA
TTGCCGGAAATATCATTAAATGCGTGGCCATTAGCGAATCAGTACGCGGCGAAGGCTTAGCGTTAACGCTGGCGACGGAA
TTGATTAATCTCGCCTGGGAGCGGCACTGCACCCATCTTTTTATTTATACCAAAACGGAATACGAAGCGCTGTTTAAACA
GTGCAGCTTTTCGACGATAGCCAGCGTCCCTGGCGTAATGGTCTTAATGGAAAATAGCGCGACCCGGTTGAAACGGTATG
CGGAATCGCTGGCGACATTGCGTCATGAGGGAAAGAAAATTGGCTGTATTGTGATGAACGCCAATCCTTTCACGAACGGC
CATCGCTATCTGATCCAACAGGCGGCGGCACAGTGCGACTGGCTGCATCTGTTCCTGGTCAAAGAAGATACATCACGCTT
TCCCTATGAAGACCGACTCGATCTGGTCCTTAAAGGGACCACCGATATCCCGCGCTTAACCGTTCACCGCGGCTCCGAAT
ACATTATTTCTCGTGCGACGTTCCCCTGCTATTTCATTAAAGAGCAGAGCGTTATTAATCACTGTTATACCGAAATCGAC
CTGAAGATTTTCCGCCAGTATCTGGCGCCCGCGCTTGGCATCACACACCGCTTTGTCGGTACGGAGCCGTTTTGCACCGT
TACCGCCCAGTACAACCTTGATATGCGTTTCTGGCTGGAGACGCCAACGCTTCCCGCCCCACCCATTACGCTGGTGGAAA
TAGAGCGGCTTTGCTTCCAGGAGACGCCGATATCCGCCTCCTGGGTACGCAAGCTGCTGGTTAAACACGATCTCACGGCT
ATCGCGCCGCTGGTTCCCGACGCCACCCTGCGCTATTTGCAGGGCATGGTCGAACGCCATCCGGGCAGCGCGGCAGCCCG
TCAAAAGTCCCCCGTATTAGCAACAGGTGAAAAATGA

Upstream 100 bases:

>100_bases
AACTCCTACTCTGACTGAAAAGAAAAAGTTATCAAGTTGCAACACAGCGCAACATATACAGAAAAGTGGCAACAAGCATA
TCACCAGGATATTTCTTACT

Downstream 100 bases:

>100_bases
AAATAAACCAGCTAGCCGTCGCAGGCACGCTTGAGTCCGGCGATGTGATGATACGCATTGCGCCGCTCGATACGCAGGAT
ATTGACCTGCAAATCAACAG

Product: citrate lyase synthetase

Products: NA

Alternate protein names: Acetate:SH-citrate lyase ligase; Citrate lyase synthetase [H]

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MFGNNVFTRVKRSENKKMAEIAHFLKENDLSVDTTVEVFITVSRDDRLIACGGIAGNIIKCVAISESVRGEGLALTLATE
LINLAWERHCTHLFIYTKTEYEALFKQCSFSTIASVPGVMVLMENSATRLKRYAESLATLRHEGKKIGCIVMNANPFTNG
HRYLIQQAAAQCDWLHLFLVKEDTSRFPYEDRLDLVLKGTTDIPRLTVHRGSEYIISRATFPCYFIKEQSVINHCYTEID
LKIFRQYLAPALGITHRFVGTEPFCTVTAQYNLDMRFWLETPTLPAPPITLVEIERLCFQETPISASWVRKLLVKHDLTA
IAPLVPDATLRYLQGMVERHPGSAAARQKSPVLATGEK

Sequences:

>Translated_358_residues
MFGNNVFTRVKRSENKKMAEIAHFLKENDLSVDTTVEVFITVSRDDRLIACGGIAGNIIKCVAISESVRGEGLALTLATE
LINLAWERHCTHLFIYTKTEYEALFKQCSFSTIASVPGVMVLMENSATRLKRYAESLATLRHEGKKIGCIVMNANPFTNG
HRYLIQQAAAQCDWLHLFLVKEDTSRFPYEDRLDLVLKGTTDIPRLTVHRGSEYIISRATFPCYFIKEQSVINHCYTEID
LKIFRQYLAPALGITHRFVGTEPFCTVTAQYNLDMRFWLETPTLPAPPITLVEIERLCFQETPISASWVRKLLVKHDLTA
IAPLVPDATLRYLQGMVERHPGSAAARQKSPVLATGEK
>Mature_358_residues
MFGNNVFTRVKRSENKKMAEIAHFLKENDLSVDTTVEVFITVSRDDRLIACGGIAGNIIKCVAISESVRGEGLALTLATE
LINLAWERHCTHLFIYTKTEYEALFKQCSFSTIASVPGVMVLMENSATRLKRYAESLATLRHEGKKIGCIVMNANPFTNG
HRYLIQQAAAQCDWLHLFLVKEDTSRFPYEDRLDLVLKGTTDIPRLTVHRGSEYIISRATFPCYFIKEQSVINHCYTEID
LKIFRQYLAPALGITHRFVGTEPFCTVTAQYNLDMRFWLETPTLPAPPITLVEIERLCFQETPISASWVRKLLVKHDLTA
IAPLVPDATLRYLQGMVERHPGSAAARQKSPVLATGEK

Specific function: Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase [H]

COG id: COG3053

COG function: function code C; Citrate lyase synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI87081765, Length=351, Percent_Identity=86.8945868945869, Blast_Score=641, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR005216
- InterPro:   IPR013166
- InterPro:   IPR004821
- InterPro:   IPR014729 [H]

Pfam domain/function: PF08218 Citrate_ly_lig [H]

EC number: =6.2.1.22 [H]

Molecular weight: Translated: 40444; Mature: 40444

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGNNVFTRVKRSENKKMAEIAHFLKENDLSVDTTVEVFITVSRDDRLIACGGIAGNIIK
CCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCEEEECCCCCCEEE
CVAISESVRGEGLALTLATELINLAWERHCTHLFIYTKTEYEALFKQCSFSTIASVPGVM
EEEECCCCCCCCEEEHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHCCCHHHHCCCCEE
VLMENSATRLKRYAESLATLRHEGKKIGCIVMNANPFTNGHRYLIQQAAAQCDWLHLFLV
EEECCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEEE
KEDTSRFPYEDRLDLVLKGTTDIPRLTVHRGSEYIISRATFPCYFIKEQSVINHCYTEID
ECCCCCCCCCCCEEEEEECCCCCCEEEEECCCCEEEECCCCCEEEEEHHHHHHHHHHHHH
LKIFRQYLAPALGITHRFVGTEPFCTVTAQYNLDMRFWLETPTLPAPPITLVEIERLCFQ
HHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCEEEEEEECCCCCCCCCHHHHHHHHHHC
ETPISASWVRKLLVKHDLTAIAPLVPDATLRYLQGMVERHPGSAAARQKSPVLATGEK
CCCCCHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHCCCCCEECCCC
>Mature Secondary Structure
MFGNNVFTRVKRSENKKMAEIAHFLKENDLSVDTTVEVFITVSRDDRLIACGGIAGNIIK
CCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCEEEECCCCCCEEE
CVAISESVRGEGLALTLATELINLAWERHCTHLFIYTKTEYEALFKQCSFSTIASVPGVM
EEEECCCCCCCCEEEHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHCCCHHHHCCCCEE
VLMENSATRLKRYAESLATLRHEGKKIGCIVMNANPFTNGHRYLIQQAAAQCDWLHLFLV
EEECCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEEE
KEDTSRFPYEDRLDLVLKGTTDIPRLTVHRGSEYIISRATFPCYFIKEQSVINHCYTEID
ECCCCCCCCCCCEEEEEECCCCCCEEEEECCCCEEEECCCCCEEEEEHHHHHHHHHHHHH
LKIFRQYLAPALGITHRFVGTEPFCTVTAQYNLDMRFWLETPTLPAPPITLVEIERLCFQ
HHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCEEEEEEECCCCCCCCCHHHHHHHHHHC
ETPISASWVRKLLVKHDLTAIAPLVPDATLRYLQGMVERHPGSAAARQKSPVLATGEK
CCCCCHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]