| Definition | Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome. |
|---|---|
| Accession | NC_003197 |
| Length | 4,857,432 |
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The map label for this gene is entA [H]
Identifier: 16763975
GI number: 16763975
Start: 659921
End: 660676
Strand: Direct
Name: entA [H]
Synonym: STM0598
Alternate gene names: 16763975
Gene position: 659921-660676 (Clockwise)
Preceding gene: 16763974
Following gene: 16763976
Centisome position: 13.59
GC content: 58.6
Gene sequence:
>756_bases ATGACCGGCTTTGATTTTTCAGACAAAACGGTATGGGTGACCGGGGCGGGGAAAGGGATCGGTTACGCGACGGCGCTGGC GTTTGTCGACGCCGGGGCGCGGGTGATCGGCTTCGATCGCGAATTTACGCAAGAGAATTATCCCTTTGCTACCGAAGTCA TGGATGTGGCGGATGCCGCACAGGTTGCGCAGGTGTGCCAGCGTGTGTTGCAAAAAACGACGCGGCTGGATGTGCTGGTC AACGCCGCCGGTATTTTGCGTATGGGAGCGACCGATGCGCTTAGCGTCGACGACTGGCAGCAGACGTTTGCGGTCAATGT GGGCGGGGCATTTAACCTGTTTTCTCAGACGATGGCGCAGTTTCGCCGTCAGCAGGGAGGGGCGATTGTCACCGTAGCCT CAGATGCGGCGCATACGCCGCGCATCGGTATGAGCGCCTACGGCGCCTCTAAAGCGGCGCTGAAAAGCTTGGCGCTAACC GTAGGGCTGGAGCTGGCGGGCTGCGGGGTGCGCTGTAATGTGGTGTCGCCTGGTTCGACTGACACCGATATGCAGCGCAC GTTATGGGTGAGTGAAGATGCCGAACAGCAGCGTATTCGCGGTTTCGGCGAACAGTTTAAGCTCGGCATACCGCTCGGTA AAATCGCCCGTCCGCAGGAGATAGCCAATACCATTTTGTTTCTTGCCTCCGATCTGGCCAGCCACATTACCTTGCAGGAT ATCGTGGTGGACGGCGGTTCAACATTGGGAGCCTGA
Upstream 100 bases:
>100_bases CGCGCTGGCGTAAAGTACACGGCGATATCGACTTCGTGATGCTGGCGAAAAACCCGACCATTGACGCCTGGTGGGCGCTG CTTTCTCGCGGGGTAGAGTA
Downstream 100 bases:
>100_bases CGATGATCTGGAAACGGCATTTAACGCTGGATGAATTGAACGCTACCAGTCAGAACACTCTGGTGGCGCATCTGGGCATT GTTTACACCCGTCTGGGCGA
Product: 2,3-dihydroxybenzoate-2,3-dehydrogenase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 251; Mature: 250
Protein sequence:
>251_residues MTGFDFSDKTVWVTGAGKGIGYATALAFVDAGARVIGFDREFTQENYPFATEVMDVADAAQVAQVCQRVLQKTTRLDVLV NAAGILRMGATDALSVDDWQQTFAVNVGGAFNLFSQTMAQFRRQQGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALT VGLELAGCGVRCNVVSPGSTDTDMQRTLWVSEDAEQQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQD IVVDGGSTLGA
Sequences:
>Translated_251_residues MTGFDFSDKTVWVTGAGKGIGYATALAFVDAGARVIGFDREFTQENYPFATEVMDVADAAQVAQVCQRVLQKTTRLDVLV NAAGILRMGATDALSVDDWQQTFAVNVGGAFNLFSQTMAQFRRQQGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALT VGLELAGCGVRCNVVSPGSTDTDMQRTLWVSEDAEQQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQD IVVDGGSTLGA >Mature_250_residues TGFDFSDKTVWVTGAGKGIGYATALAFVDAGARVIGFDREFTQENYPFATEVMDVADAAQVAQVCQRVLQKTTRLDVLVN AAGILRMGATDALSVDDWQQTFAVNVGGAFNLFSQTMAQFRRQQGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALTV GLELAGCGVRCNVVSPGSTDTDMQRTLWVSEDAEQQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDI VVDGGSTLGA
Specific function: Siderophore biosynthesis; enterobactin biosynthesis. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=261, Percent_Identity=29.5019157088123, Blast_Score=102, Evalue=5e-22, Organism=Homo sapiens, GI66933014, Length=248, Percent_Identity=31.0483870967742, Blast_Score=98, Evalue=9e-21, Organism=Homo sapiens, GI5031737, Length=262, Percent_Identity=30.1526717557252, Blast_Score=95, Evalue=5e-20, Organism=Homo sapiens, GI40254992, Length=252, Percent_Identity=30.952380952381, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI15277342, Length=254, Percent_Identity=31.496062992126, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI7705925, Length=249, Percent_Identity=29.3172690763052, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI10190704, Length=257, Percent_Identity=25.2918287937743, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI19923817, Length=256, Percent_Identity=24.21875, Blast_Score=81, Evalue=7e-16, Organism=Homo sapiens, GI33667109, Length=204, Percent_Identity=30.8823529411765, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI126723750, Length=267, Percent_Identity=26.2172284644195, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI59889578, Length=231, Percent_Identity=27.2727272727273, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI4504505, Length=190, Percent_Identity=30, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI31542939, Length=258, Percent_Identity=27.1317829457364, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI4758504, Length=199, Percent_Identity=31.6582914572864, Blast_Score=67, Evalue=1e-11, Organism=Escherichia coli, GI1786812, Length=248, Percent_Identity=90.3225806451613, Blast_Score=455, Evalue=1e-129, Organism=Escherichia coli, GI87082100, Length=256, Percent_Identity=31.640625, Blast_Score=117, Evalue=5e-28, Organism=Escherichia coli, GI1787335, Length=253, Percent_Identity=32.4110671936759, Blast_Score=116, Evalue=2e-27, Organism=Escherichia coli, GI1788459, Length=200, Percent_Identity=34, Blast_Score=98, Evalue=5e-22, Organism=Escherichia coli, GI1787905, Length=249, Percent_Identity=28.9156626506024, Blast_Score=89, Evalue=3e-19, Organism=Escherichia coli, GI1789378, Length=269, Percent_Identity=28.6245353159851, Blast_Score=84, Evalue=9e-18, Organism=Escherichia coli, GI2367175, Length=255, Percent_Identity=31.3725490196078, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI1789208, Length=255, Percent_Identity=25.0980392156863, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI1790717, Length=253, Percent_Identity=24.5059288537549, Blast_Score=82, Evalue=3e-17, Organism=Escherichia coli, GI2367365, Length=249, Percent_Identity=29.718875502008, Blast_Score=78, Evalue=6e-16, Organism=Escherichia coli, GI87082160, Length=262, Percent_Identity=27.4809160305344, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1787820, Length=178, Percent_Identity=29.2134831460674, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI1787526, Length=207, Percent_Identity=26.5700483091787, Blast_Score=64, Evalue=1e-11, Organism=Caenorhabditis elegans, GI115534694, Length=256, Percent_Identity=33.984375, Blast_Score=114, Evalue=6e-26, Organism=Caenorhabditis elegans, GI17561402, Length=257, Percent_Identity=32.6848249027237, Blast_Score=108, Evalue=3e-24, Organism=Caenorhabditis elegans, GI17563726, Length=261, Percent_Identity=32.183908045977, Blast_Score=107, Evalue=4e-24, Organism=Caenorhabditis elegans, GI17560150, Length=264, Percent_Identity=32.5757575757576, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17562990, Length=261, Percent_Identity=34.0996168582375, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=33.0827067669173, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17562908, Length=267, Percent_Identity=34.8314606741573, Blast_Score=100, Evalue=5e-22, Organism=Caenorhabditis elegans, GI17562904, Length=266, Percent_Identity=30.8270676691729, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI72000259, Length=261, Percent_Identity=33.3333333333333, Blast_Score=98, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17544670, Length=269, Percent_Identity=28.996282527881, Blast_Score=97, Evalue=6e-21, Organism=Caenorhabditis elegans, GI17560220, Length=263, Percent_Identity=31.9391634980989, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=31.4393939393939, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17531453, Length=267, Percent_Identity=32.9588014981273, Blast_Score=94, Evalue=6e-20, Organism=Caenorhabditis elegans, GI17555706, Length=251, Percent_Identity=31.0756972111554, Blast_Score=94, Evalue=9e-20, Organism=Caenorhabditis elegans, GI17560676, Length=254, Percent_Identity=29.5275590551181, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17562910, Length=266, Percent_Identity=31.203007518797, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17560332, Length=269, Percent_Identity=30.8550185873606, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI25147288, Length=252, Percent_Identity=29.3650793650794, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=29.0322580645161, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=29.718875502008, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI17538480, Length=270, Percent_Identity=28.8888888888889, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=30.6818181818182, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17559104, Length=264, Percent_Identity=28.4090909090909, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17551412, Length=268, Percent_Identity=28.3582089552239, Blast_Score=82, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17508651, Length=194, Percent_Identity=29.8969072164948, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI17536651, Length=260, Percent_Identity=28.4615384615385, Blast_Score=74, Evalue=9e-14, Organism=Caenorhabditis elegans, GI212645366, Length=245, Percent_Identity=30.2040816326531, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17568967, Length=203, Percent_Identity=30.0492610837438, Blast_Score=70, Evalue=8e-13, Organism=Caenorhabditis elegans, GI17538182, Length=228, Percent_Identity=28.5087719298246, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17508895, Length=195, Percent_Identity=29.2307692307692, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17538486, Length=266, Percent_Identity=26.6917293233083, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI193210355, Length=220, Percent_Identity=28.1818181818182, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17561272, Length=197, Percent_Identity=26.9035532994924, Blast_Score=65, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6322227, Length=198, Percent_Identity=27.7777777777778, Blast_Score=76, Evalue=4e-15, Organism=Saccharomyces cerevisiae, GI6322861, Length=191, Percent_Identity=28.7958115183246, Blast_Score=72, Evalue=1e-13, Organism=Saccharomyces cerevisiae, GI6324126, Length=257, Percent_Identity=24.124513618677, Blast_Score=70, Evalue=2e-13, Organism=Saccharomyces cerevisiae, GI6322226, Length=216, Percent_Identity=28.7037037037037, Blast_Score=67, Evalue=2e-12, Organism=Saccharomyces cerevisiae, GI6323882, Length=220, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=3e-12, Organism=Drosophila melanogaster, GI28571526, Length=253, Percent_Identity=33.201581027668, Blast_Score=110, Evalue=1e-24, Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=32.5396825396825, Blast_Score=106, Evalue=1e-23, Organism=Drosophila melanogaster, GI23397609, Length=250, Percent_Identity=33.6, Blast_Score=105, Evalue=3e-23, Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=32.5490196078431, Blast_Score=102, Evalue=2e-22, Organism=Drosophila melanogaster, GI24639444, Length=257, Percent_Identity=32.6848249027237, Blast_Score=99, Evalue=2e-21, Organism=Drosophila melanogaster, GI24643142, Length=249, Percent_Identity=30.9236947791165, Blast_Score=92, Evalue=3e-19, Organism=Drosophila melanogaster, GI24644337, Length=263, Percent_Identity=32.6996197718631, Blast_Score=92, Evalue=4e-19, Organism=Drosophila melanogaster, GI21355319, Length=251, Percent_Identity=28.2868525896414, Blast_Score=90, Evalue=2e-18, Organism=Drosophila melanogaster, GI18859837, Length=188, Percent_Identity=30.8510638297872, Blast_Score=74, Evalue=7e-14, Organism=Drosophila melanogaster, GI17737361, Length=235, Percent_Identity=29.7872340425532, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI21356301, Length=210, Percent_Identity=28.0952380952381, Blast_Score=66, Evalue=3e-11, Organism=Drosophila melanogaster, GI21358495, Length=191, Percent_Identity=27.7486910994764, Blast_Score=65, Evalue=6e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR003560 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.3.1.28 [H]
Molecular weight: Translated: 26571; Mature: 26440
Theoretical pI: Translated: 4.84; Mature: 4.84
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 3.6 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 3.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTGFDFSDKTVWVTGAGKGIGYATALAFVDAGARVIGFDREFTQENYPFATEVMDVADAA CCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEECCHHHCCCCCCHHHHHHHHHHHH QVAQVCQRVLQKTTRLDVLVNAAGILRMGATDALSVDDWQQTFAVNVGGAFNLFSQTMAQ HHHHHHHHHHHHHHHHHHHCCCHHHEEECCCCCCCCCCHHHEEEEECCCHHHHHHHHHHH FRRQQGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALTVGLELAGCGVRCNVVSPGST HHHHCCCEEEEEECCCCCCCCCCCHHCCCHHHHHHHHHHHHHHEEECCCEEEEEECCCCC DTDMQRTLWVSEDAEQQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQD CCCHHHEEEECCCHHHHHHHCCCCCEEECCCHHCCCCHHHHHHHHHHHHHHHHHHCEEEH IVVDGGSTLGA EEEECCCCCCC >Mature Secondary Structure TGFDFSDKTVWVTGAGKGIGYATALAFVDAGARVIGFDREFTQENYPFATEVMDVADAA CCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEECCHHHCCCCCCHHHHHHHHHHHH QVAQVCQRVLQKTTRLDVLVNAAGILRMGATDALSVDDWQQTFAVNVGGAFNLFSQTMAQ HHHHHHHHHHHHHHHHHHHCCCHHHEEECCCCCCCCCCHHHEEEEECCCHHHHHHHHHHH FRRQQGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALTVGLELAGCGVRCNVVSPGST HHHHCCCEEEEEECCCCCCCCCCCHHCCCHHHHHHHHHHHHHHEEECCCEEEEEECCCCC DTDMQRTLWVSEDAEQQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQD CCCHHHEEEECCCHHHHHHHCCCCCEEECCCHHCCCCHHHHHHHHHHHHHHHHHHCEEEH IVVDGGSTLGA EEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 2521622; 2521621; 9278503 [H]