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The map label for this gene is fepD [H]

Identifier: 16763969

GI number: 16763969

Start: 652565

End: 653572

Strand: Reverse

Name: fepD [H]

Synonym: STM0592

Alternate gene names: 16763969

Gene position: 653572-652565 (Counterclockwise)

Preceding gene: 16763971

Following gene: 16763968

Centisome position: 13.46

GC content: 61.21

Gene sequence:

>1008_bases
ATGTCATGCTCGTTTTCCGTGACGCGCGCGTTTGCCGTGCCCGGATTGTTGTTATTACTGAGTCTCGCCGCGGTTTTAAG
CCTGGTCATTGGCGCGAAACCGCTGCCCGCCGCCGTCGTGCTGGAGGCGTTCACCGGCGTGTGCCAAAGCGCCGATTGCA
CCATCGTCCTGGATGCGCGTTTGCCGCGTACGCTGGCCGGATTACTGGCAGGCGGCGCGTTGGGCCTCGCCGGGGCGCTC
ATGCAAACACTCACTCGCAACCCGCTCGCCGACCCGGGGATTCTGGGCGTTAACAACGGCGCCAGCTTCGCCATTGTACT
GGGCGCGGCGCTGTTTGGTTTCTCCACGCCGCTGGAACAGCTTTTCATGGCATTTAGCGGCGCGCTTATCGCATCACTGA
TTGTCGCCTTCACCGGTAGTCAGGGCGGCGGCCAGTTAAGCCCGGTCCGCCTGACACTGGCGGGCGTGGCGCTTGGCGCG
GTACTGGAAGGATTGACCAGCGGCATCGCGCTGTTAAATCCAGAGGTTTATGATCAGCTTCGCTTCTGGCAGGCGGGATC
GCTGGACATTCGTAGCCTGCAAACGTTGAAAGTCGCGCTTGCGCCCGTGGTTATCGCTGGGATCGTGGCGCTATTTCTGA
GCCGTGCGCTGAATAGCCTGAGCCTCGGCAGCGATACTGCGACGGCGCTGGGGAGTAAAGTGGCGCGCACCCAACTTATC
GGTTTACTGGCGATTACCGTCTTGTGCGGCAGCGCAACGGCGCTGGTCGGCCCTATCGCCTTTATTGGTCTGATGATGCC
GCATATGGCGCGTTGGCTGGTGGGCGCAGACCACCGTTGGTCGCTGCCGGTAACACTACTGGCAACCCCTGCTCTGCTGC
TTTTTGCCGATATTATTGGTCGTCTGTTAGTGCCGGGCGAACTCCGCGTATCGGTCGTCAGTGCGTTTATCGGCGCGCCG
GTACTTATCTTTCTGGTACGCCGTAAATCGAGCGGAGGCGGCCTGTGA

Upstream 100 bases:

>100_bases
TAATGCGAGTTTTTTTAAATATCCATTCAATGGCTGCACATGCTAACATAACCAAATAAGATAGATAACGATAATTACTA
TCATTATCAGGGAAGTTACT

Downstream 100 bases:

>100_bases
TGTTTCTTTCTCGTCGGCTTATCGTAAGCTGCCTGCTTCTGGCGGCTGGCTGCTTCGCCATTGGCTTATGGAGCCTGCAA
AGCGGTGCCGTGCCCCTTGA

Product: iron-enterobactin transporter membrane protein

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MSCSFSVTRAFAVPGLLLLLSLAAVLSLVIGAKPLPAAVVLEAFTGVCQSADCTIVLDARLPRTLAGLLAGGALGLAGAL
MQTLTRNPLADPGILGVNNGASFAIVLGAALFGFSTPLEQLFMAFSGALIASLIVAFTGSQGGGQLSPVRLTLAGVALGA
VLEGLTSGIALLNPEVYDQLRFWQAGSLDIRSLQTLKVALAPVVIAGIVALFLSRALNSLSLGSDTATALGSKVARTQLI
GLLAITVLCGSATALVGPIAFIGLMMPHMARWLVGADHRWSLPVTLLATPALLLFADIIGRLLVPGELRVSVVSAFIGAP
VLIFLVRRKSSGGGL

Sequences:

>Translated_335_residues
MSCSFSVTRAFAVPGLLLLLSLAAVLSLVIGAKPLPAAVVLEAFTGVCQSADCTIVLDARLPRTLAGLLAGGALGLAGAL
MQTLTRNPLADPGILGVNNGASFAIVLGAALFGFSTPLEQLFMAFSGALIASLIVAFTGSQGGGQLSPVRLTLAGVALGA
VLEGLTSGIALLNPEVYDQLRFWQAGSLDIRSLQTLKVALAPVVIAGIVALFLSRALNSLSLGSDTATALGSKVARTQLI
GLLAITVLCGSATALVGPIAFIGLMMPHMARWLVGADHRWSLPVTLLATPALLLFADIIGRLLVPGELRVSVVSAFIGAP
VLIFLVRRKSSGGGL
>Mature_334_residues
SCSFSVTRAFAVPGLLLLLSLAAVLSLVIGAKPLPAAVVLEAFTGVCQSADCTIVLDARLPRTLAGLLAGGALGLAGALM
QTLTRNPLADPGILGVNNGASFAIVLGAALFGFSTPLEQLFMAFSGALIASLIVAFTGSQGGGQLSPVRLTLAGVALGAV
LEGLTSGIALLNPEVYDQLRFWQAGSLDIRSLQTLKVALAPVVIAGIVALFLSRALNSLSLGSDTATALGSKVARTQLIG
LLAITVLCGSATALVGPIAFIGLMMPHMARWLVGADHRWSLPVTLLATPALLLFADIIGRLLVPGELRVSVVSAFIGAPV
LIFLVRRKSSGGGL

Specific function: Part of the binding-protein-dependent transport system for ferric enterobactin. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786805, Length=333, Percent_Identity=88.5885885885886, Blast_Score=499, Evalue=1e-142,
Organism=Escherichia coli, GI1790740, Length=307, Percent_Identity=37.1335504885993, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1790741, Length=279, Percent_Identity=39.0681003584229, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1786347, Length=281, Percent_Identity=35.9430604982206, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1788004, Length=280, Percent_Identity=39.6428571428571, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1786804, Length=331, Percent_Identity=34.7432024169184, Blast_Score=112, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 34094; Mature: 33963

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSCSFSVTRAFAVPGLLLLLSLAAVLSLVIGAKPLPAAVVLEAFTGVCQSADCTIVLDAR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEECCC
LPRTLAGLLAGGALGLAGALMQTLTRNPLADPGILGVNNGASFAIVLGAALFGFSTPLEQ
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCHHHH
LFMAFSGALIASLIVAFTGSQGGGQLSPVRLTLAGVALGAVLEGLTSGIALLNPEVYDQL
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHH
RFWQAGSLDIRSLQTLKVALAPVVIAGIVALFLSRALNSLSLGSDTATALGSKVARTQLI
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
GLLAITVLCGSATALVGPIAFIGLMMPHMARWLVGADHRWSLPVTLLATPALLLFADIIG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
RLLVPGELRVSVVSAFIGAPVLIFLVRRKSSGGGL
HHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SCSFSVTRAFAVPGLLLLLSLAAVLSLVIGAKPLPAAVVLEAFTGVCQSADCTIVLDAR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEECCC
LPRTLAGLLAGGALGLAGALMQTLTRNPLADPGILGVNNGASFAIVLGAALFGFSTPLEQ
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCHHHH
LFMAFSGALIASLIVAFTGSQGGGQLSPVRLTLAGVALGAVLEGLTSGIALLNPEVYDQL
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHH
RFWQAGSLDIRSLQTLKVALAPVVIAGIVALFLSRALNSLSLGSDTATALGSKVARTQLI
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
GLLAITVLCGSATALVGPIAFIGLMMPHMARWLVGADHRWSLPVTLLATPALLLFADIIG
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
RLLVPGELRVSVVSAFIGAPVLIFLVRRKSSGGGL
HHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1838574; 1787794; 9278503 [H]