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The map label for this gene is fdrA [H]

Identifier: 16763909

GI number: 16763909

Start: 591360

End: 593024

Strand: Direct

Name: fdrA [H]

Synonym: STM0529

Alternate gene names: 16763909

Gene position: 591360-593024 (Clockwise)

Preceding gene: 16763905

Following gene: 16763910

Centisome position: 12.17

GC content: 57.3

Gene sequence:

>1665_bases
ATGATCCACGCCTTTATTAAAAAAGGGTGTTTTCAGGACTCTGTCAGCTTAATGATTATTTCTCGAAAGCTGAGTGAGTC
CGAAAATGTTGATGATGTATCGGTAATGATGGGAACGCCTGCGAATAAGTCGCTGCTGGAAACTACCGGTTTCTGGCATG
ACGATTTTCATGGCGCTACGCCCAATGACATTTGCGTGGCGATTCGTACCGAAGCGGTAGATGACGGCATTACGCAAGTG
ATTGTGCAACAGCTCGAAGAAGCATTGCAGCAGTTGGCGCAGGGAAGCAGCGGCAGCCAGTCGTTAATCCAGGTCAGACG
CTGGGAAAGCGCCTGTCAGAAACTGCCAGAGGCGAGTCTGGCGCTGGTATCGGTGGCCGGCGAATATGCGGCGGAACTGG
CAGAGCAGGCGCTGGATCGTTCGTTGAACGTGATGATCTTCTCCGATAATGTCACGCTGGACGATGAAATCAGACTAAAA
CGCCGGGCGCGTGATAAAGGACTGCTGGTCATGGGGCCGGATTGCGGCACCGCTATGATCGCCAATACGCCGCTGGCTTT
CGCTAACGTCATGCCAGAGGGCAACATCGGGGTGATTGGCGCTTCCGGCACCGGTATTCAGGAGCTCTGTTCACAGATTG
CGCTGGCGGGGGAAGGGATTACCCATGCCATCGGGCTTGGCGGACGCGATTTGAGCGCCGAAGTCGGCGGGATCAGCGCG
CTAACGGCACTGGAGATACTCAGCGCGGATGAAAAGAGCCAGGTGCTGGCCTTTGTCTCCAAACCGCCTGCCGATGCGGT
TCGTCAGCATATTATCGCGGCGATGAAAGCCGCCGGGAAACCCGTTGTAGCGCTGTTCTTAGGGTTTTCCTCCCCCGTTG
CGCGTGAGGAAAACGTCTGGTTTGCCTCGACGCTGGATGAAGCCGCCCGACTGGCATGTTTATTGTCTCGCGTGACGTCG
CAGCGTAAAGAAATGGTTTCAACAGGCGGCGTGATTCGTGGTCTCTATACCGGCGGAACGCTGGCGGCGGAAGCGGCGGG
GCTGCTGGCCGGCTATCTGGGCGTCGCGGCGGATACGGAACATCACCATGGCATGATGCTTGACGCTGACGGCCACCAGA
TTATCGATCTGGGCGATGACTTTTATACCGTTGGGCGACCACATCCGATGATTGACCCGGCGTTACGTAATCAGCTTATC
GCCGGGCTTGGCGCACAGCCGCAGGTACGCGTGTTATTAGTGGACGTCGTTATTGGTTTTGGCGCGACCGCCGATCCCGC
CGCATCGCTGATTCAGGCCTGGCAGAAGGCATGCGACGCACGCGCCAGAGACCAGCCGCTGTTCGCCATCGCAACCGTCA
CCGGAACGGAACGCGATCCTCAGTGCCGCTCGCAACAAATCGCCGCGCTCGAAGATGCCGGCATCACGGTAGTGGATTCC
CTTCCCGAAGCCACTCTGTTGGCCGCGGAACTGATTCGACCCACTCTCTCTTCTACTCATCCATCAGCCCCCCGGTTACT
GGAAGCGGTGGCGGTGATTAATGCCGGGTTACGTAGCTTCGCGCTGGATTTACAGGCTGCCGGTATGCCCGTGGTGCACT
ACCAGTGGGCGCCTGTCGCTGGCGGTAATAAAAAACTGGCTCGTCTGTTAGAACGTTTGCAATAA

Upstream 100 bases:

>100_bases
TATTTACCCTCCCGGATATATACCGTGAAGCGCACATTAACACTGCTCGTGCAATTGCAATGGGTGCAATTGCAATGGGT
GCAATTATTAAGGAGTTGTT

Downstream 100 bases:

>100_bases
GGGGTTCCCATGTTTACATCAGTGGCGCAAGCCAACGCTGCAGTCATCGAACAAATTCGTCGCGCACGTCCGCACTGGCT
GGATGTGAAGCCAGCTTCTT

Product: membrane protein FdrA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 554; Mature: 554

Protein sequence:

>554_residues
MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKSLLETTGFWHDDFHGATPNDICVAIRTEAVDDGITQV
IVQQLEEALQQLAQGSSGSQSLIQVRRWESACQKLPEASLALVSVAGEYAAELAEQALDRSLNVMIFSDNVTLDDEIRLK
RRARDKGLLVMGPDCGTAMIANTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSAEVGGISA
LTALEILSADEKSQVLAFVSKPPADAVRQHIIAAMKAAGKPVVALFLGFSSPVAREENVWFASTLDEAARLACLLSRVTS
QRKEMVSTGGVIRGLYTGGTLAAEAAGLLAGYLGVAADTEHHHGMMLDADGHQIIDLGDDFYTVGRPHPMIDPALRNQLI
AGLGAQPQVRVLLVDVVIGFGATADPAASLIQAWQKACDARARDQPLFAIATVTGTERDPQCRSQQIAALEDAGITVVDS
LPEATLLAAELIRPTLSSTHPSAPRLLEAVAVINAGLRSFALDLQAAGMPVVHYQWAPVAGGNKKLARLLERLQ

Sequences:

>Translated_554_residues
MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKSLLETTGFWHDDFHGATPNDICVAIRTEAVDDGITQV
IVQQLEEALQQLAQGSSGSQSLIQVRRWESACQKLPEASLALVSVAGEYAAELAEQALDRSLNVMIFSDNVTLDDEIRLK
RRARDKGLLVMGPDCGTAMIANTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSAEVGGISA
LTALEILSADEKSQVLAFVSKPPADAVRQHIIAAMKAAGKPVVALFLGFSSPVAREENVWFASTLDEAARLACLLSRVTS
QRKEMVSTGGVIRGLYTGGTLAAEAAGLLAGYLGVAADTEHHHGMMLDADGHQIIDLGDDFYTVGRPHPMIDPALRNQLI
AGLGAQPQVRVLLVDVVIGFGATADPAASLIQAWQKACDARARDQPLFAIATVTGTERDPQCRSQQIAALEDAGITVVDS
LPEATLLAAELIRPTLSSTHPSAPRLLEAVAVINAGLRSFALDLQAAGMPVVHYQWAPVAGGNKKLARLLERLQ
>Mature_554_residues
MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKSLLETTGFWHDDFHGATPNDICVAIRTEAVDDGITQV
IVQQLEEALQQLAQGSSGSQSLIQVRRWESACQKLPEASLALVSVAGEYAAELAEQALDRSLNVMIFSDNVTLDDEIRLK
RRARDKGLLVMGPDCGTAMIANTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSAEVGGISA
LTALEILSADEKSQVLAFVSKPPADAVRQHIIAAMKAAGKPVVALFLGFSSPVAREENVWFASTLDEAARLACLLSRVTS
QRKEMVSTGGVIRGLYTGGTLAAEAAGLLAGYLGVAADTEHHHGMMLDADGHQIIDLGDDFYTVGRPHPMIDPALRNQLI
AGLGAQPQVRVLLVDVVIGFGATADPAASLIQAWQKACDARARDQPLFAIATVTGTERDPQCRSQQIAALEDAGITVVDS
LPEATLLAAELIRPTLSSTHPSAPRLLEAVAVINAGLRSFALDLQAAGMPVVHYQWAPVAGGNKKLARLLERLQ

Specific function: Not known; multicopy suppressor of dominant negative ftsH mutations [H]

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli yahF and some, to bacterial sucD [H]

Homologues:

Organism=Escherichia coli, GI1786729, Length=555, Percent_Identity=82.8828828828829, Blast_Score=914, Evalue=0.0,
Organism=Escherichia coli, GI1786513, Length=512, Percent_Identity=37.3046875, Blast_Score=293, Evalue=3e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003781
- InterPro:   IPR005811
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: NA

Molecular weight: Translated: 58537; Mature: 58537

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKSLLETTGFWHDDFHGAT
CCHHHHHCCCCCCCCCEEEEEHHHCCCCCCCCEEEEECCCCCCHHHHHCCCCCCCCCCCC
PNDICVAIRTEAVDDGITQVIVQQLEEALQQLAQGSSGSQSLIQVRRWESACQKLPEASL
CCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHH
ALVSVAGEYAAELAEQALDRSLNVMIFSDNVTLDDEIRLKRRARDKGLLVMGPDCGTAMI
HHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEECCCCCCEEE
ANTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSAEVGGISA
ECCCHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCHHH
LTALEILSADEKSQVLAFVSKPPADAVRQHIIAAMKAAGKPVVALFLGFSSPVAREENVW
HHHHHHHCCCCHHHEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEE
FASTLDEAARLACLLSRVTSQRKEMVSTGGVIRGLYTGGTLAAEAAGLLAGYLGVAADTE
EHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCC
HHHGMMLDADGHQIIDLGDDFYTVGRPHPMIDPALRNQLIAGLGAQPQVRVLLVDVVIGF
CCCCEEEECCCCEEEECCCCEEECCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEHHHHC
GATADPAASLIQAWQKACDARARDQPLFAIATVTGTERDPQCRSQQIAALEDAGITVVDS
CCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCEEEECC
LPEATLLAAELIRPTLSSTHPSAPRLLEAVAVINAGLRSFALDLQAAGMPVVHYQWAPVA
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
GGNKKLARLLERLQ
CCCHHHHHHHHHCC
>Mature Secondary Structure
MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKSLLETTGFWHDDFHGAT
CCHHHHHCCCCCCCCCEEEEEHHHCCCCCCCCEEEEECCCCCCHHHHHCCCCCCCCCCCC
PNDICVAIRTEAVDDGITQVIVQQLEEALQQLAQGSSGSQSLIQVRRWESACQKLPEASL
CCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHH
ALVSVAGEYAAELAEQALDRSLNVMIFSDNVTLDDEIRLKRRARDKGLLVMGPDCGTAMI
HHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEEECCCCCCEEE
ANTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSAEVGGISA
ECCCHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCHHH
LTALEILSADEKSQVLAFVSKPPADAVRQHIIAAMKAAGKPVVALFLGFSSPVAREENVW
HHHHHHHCCCCHHHEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEE
FASTLDEAARLACLLSRVTSQRKEMVSTGGVIRGLYTGGTLAAEAAGLLAGYLGVAADTE
EHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCC
HHHGMMLDADGHQIIDLGDDFYTVGRPHPMIDPALRNQLIAGLGAQPQVRVLLVDVVIGF
CCCCEEEECCCCEEEECCCCEEECCCCCCCCCHHHHHHHHHCCCCCCCCEEEEEEHHHHC
GATADPAASLIQAWQKACDARARDQPLFAIATVTGTERDPQCRSQQIAALEDAGITVVDS
CCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCEEEECC
LPEATLLAAELIRPTLSSTHPSAPRLLEAVAVINAGLRSFALDLQAAGMPVVHYQWAPVA
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
GGNKKLARLLERLQ
CCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7500942; 9278503; 3309887 [H]