BacMap

Definition	Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome.
Accession	NC_003197
Length	4,857,432

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The map label for this gene is ybbO [H]

Identifier: 16763885

GI number: 16763885

Start: 564929

End: 565699

Strand: Reverse

Name: ybbO [H]

Synonym: STM0505

Alternate gene names: 16763885

Gene position: 565699-564929 (Counterclockwise)

Preceding gene: 16763886

Following gene: 16763884

Centisome position: 11.65

GC content: 54.99

Gene sequence:

>771_bases
ATGCAAAAATCGGTCTTAATAACAGGATGTTCCAGCGGAATCGGTCTGGACAGCGCGCTTGAGCTTAAACGCCAGGGCTT
TCAAATCCTGGCGGGCTGCCGCAAACCTGATGATGTCGCCCGGATGAACAGTATGGGATTTACCGGCGTGTTGATCGATC
TCGACTCCCCTGAAAGCGTGGATCGTGCCGCCGATGAAGTGATCGCCCTGACCGATAATCGTCTGTATGGGATCTTTAAC
AATGCCGGCTACGGCGTGTATGGCCCCCTTTCCACCATCAGCCGTGAGCAGATGGAGCAACAGTTTTCCAGTAATTTCTT
CGGCGCGCATCAGCTTACTATGCGCTTACTTCCCGCCATGTTGCCGCATGGCGAAGGACGCATTGTGATGACCTCATCGG
TGATGGGGCTGATTTCCACCCCAGGGCGCGGCGCTTACGCCGCCAGCAAATATGCGCTCGAAGCCTGGTCTGACGCGCTA
CGTATGGAGCTACGGCACACAGGCATTAAAGTGAGCCTGATAGAACCGGGGCCGATTCGTACCCGTTTTACCGATAACGT
TAACCAGACGCAGCGTGATAAACCGGTAGAAAATCCCGGCATCGCCGCACGTTTCACCCGCGATCCTGACGCGGTAGTAG
CGAAAGTACGTCATGCTTTTGCAAGCGATAAACCCAGGCTGCGCTATCCCGTTACGCTGGTCACCTGGGCGGTGATGGCG
CTGAAACGCATATTGCCGGGCCGGATGCTGGATAAAATTTTACAAAGCTGA

Upstream 100 bases:

>100_bases
CCTATGTGACTGGAGTAAACGAACGCACAGGCAACTTGAAGTATGACGGATATAGTTAACCACGACTCTTAAATCAACGG
AGATCCTGACAGGTAAAGTT

Downstream 100 bases:

>100_bases
GTTGAAGCGCGCCCGTCAGCCCCCATGTAAACGTGACACAGACAAAAGAGAGCGACGCCATGTCCGTACAGAACATTGTC
AATATTAATGAATCCAACCT

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MQKSVLITGCSSGIGLDSALELKRQGFQILAGCRKPDDVARMNSMGFTGVLIDLDSPESVDRAADEVIALTDNRLYGIFN
NAGYGVYGPLSTISREQMEQQFSSNFFGAHQLTMRLLPAMLPHGEGRIVMTSSVMGLISTPGRGAYAASKYALEAWSDAL
RMELRHTGIKVSLIEPGPIRTRFTDNVNQTQRDKPVENPGIAARFTRDPDAVVAKVRHAFASDKPRLRYPVTLVTWAVMA
LKRILPGRMLDKILQS

Sequences:

>Translated_256_residues
MQKSVLITGCSSGIGLDSALELKRQGFQILAGCRKPDDVARMNSMGFTGVLIDLDSPESVDRAADEVIALTDNRLYGIFN
NAGYGVYGPLSTISREQMEQQFSSNFFGAHQLTMRLLPAMLPHGEGRIVMTSSVMGLISTPGRGAYAASKYALEAWSDAL
RMELRHTGIKVSLIEPGPIRTRFTDNVNQTQRDKPVENPGIAARFTRDPDAVVAKVRHAFASDKPRLRYPVTLVTWAVMA
LKRILPGRMLDKILQS
>Mature_256_residues
MQKSVLITGCSSGIGLDSALELKRQGFQILAGCRKPDDVARMNSMGFTGVLIDLDSPESVDRAADEVIALTDNRLYGIFN
NAGYGVYGPLSTISREQMEQQFSSNFFGAHQLTMRLLPAMLPHGEGRIVMTSSVMGLISTPGRGAYAASKYALEAWSDAL
RMELRHTGIKVSLIEPGPIRTRFTDNVNQTQRDKPVENPGIAARFTRDPDAVVAKVRHAFASDKPRLRYPVTLVTWAVMA
LKRILPGRMLDKILQS

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7657478, Length=251, Percent_Identity=31.8725099601594, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI50726952, Length=278, Percent_Identity=32.3741007194245, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI40548397, Length=195, Percent_Identity=33.8461538461538, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI214010158, Length=195, Percent_Identity=33.8461538461538, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI214010156, Length=195, Percent_Identity=33.8461538461538, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI22758144, Length=195, Percent_Identity=33.8461538461538, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI150247226, Length=254, Percent_Identity=32.2834645669291, Blast_Score=111, Evalue=6e-25,
Organism=Homo sapiens, GI44680136, Length=287, Percent_Identity=28.9198606271777, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI44680133, Length=287, Percent_Identity=28.9198606271777, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI17738292, Length=287, Percent_Identity=28.9198606271777, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI22507405, Length=258, Percent_Identity=31.3953488372093, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI19743808, Length=199, Percent_Identity=34.1708542713568, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI223718074, Length=195, Percent_Identity=33.8461538461538, Blast_Score=98, Evalue=8e-21,
Organism=Homo sapiens, GI119392083, Length=210, Percent_Identity=35.7142857142857, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI20149619, Length=198, Percent_Identity=30.3030303030303, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI7706318, Length=206, Percent_Identity=28.6407766990291, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI4504503, Length=204, Percent_Identity=29.9019607843137, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI142976729, Length=261, Percent_Identity=27.5862068965517, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI157739938, Length=195, Percent_Identity=30.7692307692308, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI210032110, Length=191, Percent_Identity=30.8900523560209, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI4503817, Length=208, Percent_Identity=27.8846153846154, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI32483357, Length=189, Percent_Identity=24.8677248677249, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1786701, Length=255, Percent_Identity=90.9803921568627, Blast_Score=489, Evalue=1e-140,
Organism=Escherichia coli, GI87082100, Length=224, Percent_Identity=29.0178571428571, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1787335, Length=196, Percent_Identity=27.0408163265306, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789378, Length=203, Percent_Identity=29.064039408867, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786812, Length=179, Percent_Identity=26.8156424581006, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI115534660, Length=283, Percent_Identity=27.9151943462898, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17557780, Length=297, Percent_Identity=28.2828282828283, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI193210355, Length=258, Percent_Identity=29.4573643410853, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17507613, Length=265, Percent_Identity=27.1698113207547, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI32563809, Length=265, Percent_Identity=27.1698113207547, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17570069, Length=192, Percent_Identity=31.7708333333333, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI71997402, Length=185, Percent_Identity=31.3513513513514, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17559962, Length=203, Percent_Identity=31.0344827586207, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=221, Percent_Identity=27.1493212669683, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322067, Length=189, Percent_Identity=29.1005291005291, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6323882, Length=200, Percent_Identity=28.5, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21358495, Length=194, Percent_Identity=32.9896907216495, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24651139, Length=240, Percent_Identity=32.0833333333333, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21356301, Length=219, Percent_Identity=27.8538812785388, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28571526, Length=240, Percent_Identity=27.0833333333333, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI45554248, Length=200, Percent_Identity=32.5, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24640117, Length=200, Percent_Identity=32.5, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24644339, Length=192, Percent_Identity=28.6458333333333, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21357041, Length=188, Percent_Identity=28.7234042553192, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24643142, Length=198, Percent_Identity=26.2626262626263, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24580925, Length=192, Percent_Identity=28.125, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28140; Mature: 28140

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKSVLITGCSSGIGLDSALELKRQGFQILAGCRKPDDVARMNSMGFTGVLIDLDSPESV
CCCCEEEEECCCCCCCHHHHHHHHCCHHHHHCCCCCHHHHHHHCCCCEEEEEECCCCHHH
DRAADEVIALTDNRLYGIFNNAGYGVYGPLSTISREQMEQQFSSNFFGAHQLTMRLLPAM
HHHHHHEEEEECCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LPHGEGRIVMTSSVMGLISTPGRGAYAASKYALEAWSDALRMELRHTGIKVSLIEPGPIR
CCCCCCCEEEEECCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCC
TRFTDNVNQTQRDKPVENPGIAARFTRDPDAVVAKVRHAFASDKPRLRYPVTLVTWAVMA
EEECCCCCHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHH
LKRILPGRMLDKILQS
HHHHCCHHHHHHHHCC
>Mature Secondary Structure
MQKSVLITGCSSGIGLDSALELKRQGFQILAGCRKPDDVARMNSMGFTGVLIDLDSPESV
CCCCEEEEECCCCCCCHHHHHHHHCCHHHHHCCCCCHHHHHHHCCCCEEEEEECCCCHHH
DRAADEVIALTDNRLYGIFNNAGYGVYGPLSTISREQMEQQFSSNFFGAHQLTMRLLPAM
HHHHHHEEEEECCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LPHGEGRIVMTSSVMGLISTPGRGAYAASKYALEAWSDALRMELRHTGIKVSLIEPGPIR
CCCCCCCEEEEECCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCC
TRFTDNVNQTQRDKPVENPGIAARFTRDPDAVVAKVRHAFASDKPRLRYPVTLVTWAVMA
EEECCCCCHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHH
LKRILPGRMLDKILQS
HHHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]