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The map label for this gene is cypD [H]

Identifier: 16763833

GI number: 16763833

Start: 508668

End: 510539

Strand: Direct

Name: cypD [H]

Synonym: STM0452

Alternate gene names: 16763833

Gene position: 508668-510539 (Clockwise)

Preceding gene: 16763832

Following gene: 16763834

Centisome position: 10.47

GC content: 52.4

Gene sequence:

>1872_bases
ATGATGGACAGCTTACGCACGGCTGCAAACAGTCTCGTGCTCAAGATTATTTTCGTTATCATTATCGTGTCGTTCATTTT
GACCGGCGTTAGTGGTTACCTGATTGGCGGAAGCAATAACTACGCCGCAAAAGTGAATGGCCAGGAAATCAGCCGGGCAC
AGTTTGAGAATGCGTTTAACAACGAACGTAACCGTATGCAGCAGCAGTTGGGCGACAGGTATTCTGAACTGGCGGCCAAC
GAAGGTTATATGAAAAGCCTGCGCCAGCAGGTGCTGAATCGTCTGATAGATGAAGCGCTGTTGGATCAATATTCCCGCGA
ACTGAAACTGGGCATCAGCGATGAGCAGGTAAAGCAGGCGATTTTCGCCACTCCCGCTTTTCAGGTGGACGGTAAGTTTG
ACAACAACCGCTATAACGCGATTGTGAATCAGATGGGAATGACCGCCGATCAGTACGCTCAGGCGCTGCGTAACCAGCTT
ACCACTCAGCAACTGATCAACGGCGTGGCCGGTACTGATTTTATGCTGAAAGGGGAAACCGACGAACTGGCGGCATTAGT
CTCTCAACAGCGCGTGGTGCGTGAAGCCGTTATTGATGTCAACGCGCTGGCGGCGAAGCAGCAGGTGACCGATCAGGAAG
TGTCCAGCTACTACGATCAGAATAAAGTCCGCTTTATGACGCCGGAACAGTTCCGCGTAAGCTATATCAAGCTGGATGCC
GCGACGATGCAGGCACCGGTCAGCGATGCGGATATTCAGGCCTATTATGACCAGCATGTAGATCAGTTTACTCAGCCGGA
GCGTATTCGTTACAGCATTATTCAGACCAAAACGGAAGATGATGCGAAAGCGGTACTGGATGCGCTGAACAAGGGCGAAG
ATTTCGCCACGCTGGCGAAAGAGAAATCTACCGATATCATCTCTGCGCGTAATGGCGGCGATATGGGCTGGCTGGAAGAG
TCTGCCACGGTGCCGGAACTGAAAAACGCCGGATTAAAAGAAAAAGGCCAGATATCTGGCGTGATTAAGTCGTCTGTCGG
TTTTCTGGTGGCGCGTCTGGATGATATTCAGCCTGCCAAAGTGAAACCGTTAAGCGAGGTTCGCGACGACATTGCCGCGA
AAGTGAAACAAGAAAAAGCGCTGGATGCTTACTATGCGTTGCAGCAGAAAGTGAGCGATGCGGCAAGCAACGACAATGAG
TCGTTAGCAGGCGCTGAACAGGTCGCTGGCGTAAAAGCCGTTGAAACCGGCTGGTTTAGCCGTGACACCTTACCGGAAGA
GCTGAACTTCAAACCGGTAGCCGATGCTATCTTTAATGGCGGTCTGGTGGGCGAAAACGGTACGCCGGGGCCGAATTCAG
ACATTATCACCGTGGATGGTGACCGGGCTTTTGTCGTACGCGTGAGCGAACATAAACCTGAAGCCGTGAAGCCGTTGGCA
GAAGTGAAAGAACAGGTCACTGCCCTGGTGAAGCATAATAAAGCGGAACAACAGGCGAAGCTGGATGCGGAGAAACTGCT
GGTCGAGCTGAAAGCGGGCAAAGGCGCGGAAGCGATGAAAGCGGCGGGGCTGAGTTTTGGCGAGCCTAAAACGTTAAGTC
GTACCAGTCAGGATCCGGTGAGTCAGGCGGCCTTTGCGTTAAGCCTTCCGACGAAAGATAAGCCAGTTTATGGCGTGGCG
AACGATATGCAGGGTAACGTCGTTCTGCTGGCGTTTGACGAGGTGAAAGCGGGCGCCATGCCGGAAGCGCAGAAAAAAGC
GATGGTGCAGGGCATCACGCAGAACAATGCGCAAATTGTCTTTGAGGCGCTGATGAGCAATCTGCGTAAAGAGGCGAAAA
TCAAAATCGGCGACGCTCTGGAACAGCAGTAA

Upstream 100 bases:

>100_bases
TTGCGTCGACGCGGCGACTGAGCGAATCACTCGGTAGCCAGCGGAGAAGCCGCCTGAAAGATAAAGTGTAAAGTCACCTA
CAGCGGAGTGTGGTTACACC

Downstream 100 bases:

>100_bases
TCGTCGAGGCGTTCGCAAAAAATTGCAAAACGTTGTATCCCACAAAGGCCGCTTTCGCGGCCTTTTCCATTTCTGAGAAT
TGCCGTTTGTTCGTTTTTCT

Product: peptidyl-prolyl cis-trans isomerase (rotamase D)

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 623; Mature: 623

Protein sequence:

>623_residues
MMDSLRTAANSLVLKIIFVIIIVSFILTGVSGYLIGGSNNYAAKVNGQEISRAQFENAFNNERNRMQQQLGDRYSELAAN
EGYMKSLRQQVLNRLIDEALLDQYSRELKLGISDEQVKQAIFATPAFQVDGKFDNNRYNAIVNQMGMTADQYAQALRNQL
TTQQLINGVAGTDFMLKGETDELAALVSQQRVVREAVIDVNALAAKQQVTDQEVSSYYDQNKVRFMTPEQFRVSYIKLDA
ATMQAPVSDADIQAYYDQHVDQFTQPERIRYSIIQTKTEDDAKAVLDALNKGEDFATLAKEKSTDIISARNGGDMGWLEE
SATVPELKNAGLKEKGQISGVIKSSVGFLVARLDDIQPAKVKPLSEVRDDIAAKVKQEKALDAYYALQQKVSDAASNDNE
SLAGAEQVAGVKAVETGWFSRDTLPEELNFKPVADAIFNGGLVGENGTPGPNSDIITVDGDRAFVVRVSEHKPEAVKPLA
EVKEQVTALVKHNKAEQQAKLDAEKLLVELKAGKGAEAMKAAGLSFGEPKTLSRTSQDPVSQAAFALSLPTKDKPVYGVA
NDMQGNVVLLAFDEVKAGAMPEAQKKAMVQGITQNNAQIVFEALMSNLRKEAKIKIGDALEQQ

Sequences:

>Translated_623_residues
MMDSLRTAANSLVLKIIFVIIIVSFILTGVSGYLIGGSNNYAAKVNGQEISRAQFENAFNNERNRMQQQLGDRYSELAAN
EGYMKSLRQQVLNRLIDEALLDQYSRELKLGISDEQVKQAIFATPAFQVDGKFDNNRYNAIVNQMGMTADQYAQALRNQL
TTQQLINGVAGTDFMLKGETDELAALVSQQRVVREAVIDVNALAAKQQVTDQEVSSYYDQNKVRFMTPEQFRVSYIKLDA
ATMQAPVSDADIQAYYDQHVDQFTQPERIRYSIIQTKTEDDAKAVLDALNKGEDFATLAKEKSTDIISARNGGDMGWLEE
SATVPELKNAGLKEKGQISGVIKSSVGFLVARLDDIQPAKVKPLSEVRDDIAAKVKQEKALDAYYALQQKVSDAASNDNE
SLAGAEQVAGVKAVETGWFSRDTLPEELNFKPVADAIFNGGLVGENGTPGPNSDIITVDGDRAFVVRVSEHKPEAVKPLA
EVKEQVTALVKHNKAEQQAKLDAEKLLVELKAGKGAEAMKAAGLSFGEPKTLSRTSQDPVSQAAFALSLPTKDKPVYGVA
NDMQGNVVLLAFDEVKAGAMPEAQKKAMVQGITQNNAQIVFEALMSNLRKEAKIKIGDALEQQ
>Mature_623_residues
MMDSLRTAANSLVLKIIFVIIIVSFILTGVSGYLIGGSNNYAAKVNGQEISRAQFENAFNNERNRMQQQLGDRYSELAAN
EGYMKSLRQQVLNRLIDEALLDQYSRELKLGISDEQVKQAIFATPAFQVDGKFDNNRYNAIVNQMGMTADQYAQALRNQL
TTQQLINGVAGTDFMLKGETDELAALVSQQRVVREAVIDVNALAAKQQVTDQEVSSYYDQNKVRFMTPEQFRVSYIKLDA
ATMQAPVSDADIQAYYDQHVDQFTQPERIRYSIIQTKTEDDAKAVLDALNKGEDFATLAKEKSTDIISARNGGDMGWLEE
SATVPELKNAGLKEKGQISGVIKSSVGFLVARLDDIQPAKVKPLSEVRDDIAAKVKQEKALDAYYALQQKVSDAASNDNE
SLAGAEQVAGVKAVETGWFSRDTLPEELNFKPVADAIFNGGLVGENGTPGPNSDIITVDGDRAFVVRVSEHKPEAVKPLA
EVKEQVTALVKHNKAEQQAKLDAEKLLVELKAGKGAEAMKAAGLSFGEPKTLSRTSQDPVSQAAFALSLPTKDKPVYGVA
NDMQGNVVLLAFDEVKAGAMPEAQKKAMVQGITQNNAQIVFEALMSNLRKEAKIKIGDALEQQ

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=624, Percent_Identity=88.6217948717949, Blast_Score=1123, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 68130; Mature: 68130

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDSLRTAANSLVLKIIFVIIIVSFILTGVSGYLIGGSNNYAAKVNGQEISRAQFENAFN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCHHHHHHHHHHHHH
NERNRMQQQLGDRYSELAANEGYMKSLRQQVLNRLIDEALLDQYSRELKLGISDEQVKQA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
IFATPAFQVDGKFDNNRYNAIVNQMGMTADQYAQALRNQLTTQQLINGVAGTDFMLKGET
HHCCCCEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCH
DELAALVSQQRVVREAVIDVNALAAKQQVTDQEVSSYYDQNKVRFMTPEQFRVSYIKLDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHEEEEEEEEH
ATMQAPVSDADIQAYYDQHVDQFTQPERIRYSIIQTKTEDDAKAVLDALNKGEDFATLAK
HHHHCCCCCCHHHHHHHHHHHHCCCCHHHEEHHHHCCCCHHHHHHHHHHHCCCHHHHHHH
EKSTDIISARNGGDMGWLEESATVPELKNAGLKEKGQISGVIKSSVGFLVARLDDIQPAK
HCCCCEEECCCCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
VKPLSEVRDDIAAKVKQEKALDAYYALQQKVSDAASNDNESLAGAEQVAGVKAVETGWFS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHCCCHHHHCCCCC
RDTLPEELNFKPVADAIFNGGLVGENGTPGPNSDIITVDGDRAFVVRVSEHKPEAVKPLA
CCCCCHHCCCCHHHHHHHCCCEECCCCCCCCCCCEEEECCCEEEEEEECCCCCHHHHHHH
EVKEQVTALVKHNKAEQQAKLDAEKLLVELKAGKGAEAMKAAGLSFGEPKTLSRTSQDPV
HHHHHHHHHHHHCHHHHHHHHCHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCHH
SQAAFALSLPTKDKPVYGVANDMQGNVVLLAFDEVKAGAMPEAQKKAMVQGITQNNAQIV
HHHHEEEECCCCCCCCEEECCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHH
FEALMSNLRKEAKIKIGDALEQQ
HHHHHHHHHHHHEEEECHHHCCC
>Mature Secondary Structure
MMDSLRTAANSLVLKIIFVIIIVSFILTGVSGYLIGGSNNYAAKVNGQEISRAQFENAFN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEECCHHHHHHHHHHHHH
NERNRMQQQLGDRYSELAANEGYMKSLRQQVLNRLIDEALLDQYSRELKLGISDEQVKQA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
IFATPAFQVDGKFDNNRYNAIVNQMGMTADQYAQALRNQLTTQQLINGVAGTDFMLKGET
HHCCCCEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCH
DELAALVSQQRVVREAVIDVNALAAKQQVTDQEVSSYYDQNKVRFMTPEQFRVSYIKLDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHEEEEEEEEH
ATMQAPVSDADIQAYYDQHVDQFTQPERIRYSIIQTKTEDDAKAVLDALNKGEDFATLAK
HHHHCCCCCCHHHHHHHHHHHHCCCCHHHEEHHHHCCCCHHHHHHHHHHHCCCHHHHHHH
EKSTDIISARNGGDMGWLEESATVPELKNAGLKEKGQISGVIKSSVGFLVARLDDIQPAK
HCCCCEEECCCCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
VKPLSEVRDDIAAKVKQEKALDAYYALQQKVSDAASNDNESLAGAEQVAGVKAVETGWFS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHCCCHHHHCCCCC
RDTLPEELNFKPVADAIFNGGLVGENGTPGPNSDIITVDGDRAFVVRVSEHKPEAVKPLA
CCCCCHHCCCCHHHHHHHCCCEECCCCCCCCCCCEEEECCCEEEEEEECCCCCHHHHHHH
EVKEQVTALVKHNKAEQQAKLDAEKLLVELKAGKGAEAMKAAGLSFGEPKTLSRTSQDPV
HHHHHHHHHHHHCHHHHHHHHCHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCHH
SQAAFALSLPTKDKPVYGVANDMQGNVVLLAFDEVKAGAMPEAQKKAMVQGITQNNAQIV
HHHHEEEECCCCCCCCEEECCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCHHHH
FEALMSNLRKEAKIKIGDALEQQ
HHHHHHHHHHHHEEEECHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]