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The map label for this gene is bolA [H]

Identifier: 16763827

GI number: 16763827

Start: 501001

End: 501318

Strand: Direct

Name: bolA [H]

Synonym: STM0446

Alternate gene names: 16763827

Gene position: 501001-501318 (Clockwise)

Preceding gene: 16763819

Following gene: 16763828

Centisome position: 10.31

GC content: 49.06

Gene sequence:

>318_bases
ATGATGATACGTGAGCAAATAGAAGAAAAATTAAGGACAGCGTTCGACCCCGTGTTTCTCGAAGTTGTGGATGAAAGCTA
TCGTCACAATGTTCCAGCAGGATCGGAAAGCCATTTTAAGGTCGTGCTGGTGAGCGATCGCTTTACAGGCGAACGTTTTC
TTAATCGTCATCGGATGATTTACGGTACGTTAACGGCGGAACTTTCCACAACCGTACATGCGCTGGCACTGCATACTTAT
ACCCTCAAAGAGTGGGAAGGATTGCAGGATACTATCTTCGCGTCGCCTCCTTGTCGCGGCGCGGGAAGCATCGCGTAG

Upstream 100 bases:

>100_bases
CGAAAGCTAAATTTTTGTTGTCATGCTGTAATGGAAACGGTAAAAGCGGCTAGTATTTAAAGGGATGGGTGACATCACAG
CGTTGTCGGAGGAGATTTTC

Downstream 100 bases:

>100_bases
CAAAACGGATTTGCAACTACCTCCGCTTTTCCAGTATGTTGCTACAGAATTATGTGAAAACGGCCTGCGGGCCGTTTTGT
TTTGTCTGAATTTTGAGCGT

Product: transcriptional regulator BolA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 105; Mature: 105

Protein sequence:

>105_residues
MMIREQIEEKLRTAFDPVFLEVVDESYRHNVPAGSESHFKVVLVSDRFTGERFLNRHRMIYGTLTAELSTTVHALALHTY
TLKEWEGLQDTIFASPPCRGAGSIA

Sequences:

>Translated_105_residues
MMIREQIEEKLRTAFDPVFLEVVDESYRHNVPAGSESHFKVVLVSDRFTGERFLNRHRMIYGTLTAELSTTVHALALHTY
TLKEWEGLQDTIFASPPCRGAGSIA
>Mature_105_residues
MMIREQIEEKLRTAFDPVFLEVVDESYRHNVPAGSESHFKVVLVSDRFTGERFLNRHRMIYGTLTAELSTTVHALALHTY
TLKEWEGLQDTIFASPPCRGAGSIA

Specific function: Plays an important role in general stress response (heat shock, acidic stress, oxidative stress, carbon-starvation stress and osmotic shock). Involved in morphogenetic pathway. Has a role in the induction of the expression of dacA (PBP5), dacC (PBP6) and

COG id: COG0271

COG function: function code T; Stress-induced morphogen (activity unknown)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bolA/yrbA family [H]

Homologues:

Organism=Homo sapiens, GI7705638, Length=99, Percent_Identity=42.4242424242424, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI87081740, Length=105, Percent_Identity=92.3809523809524, Blast_Score=206, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI17541430, Length=95, Percent_Identity=47.3684210526316, Blast_Score=92, Evalue=5e-20,
Organism=Drosophila melanogaster, GI221459039, Length=103, Percent_Identity=39.8058252427184, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002634 [H]

Pfam domain/function: PF01722 BolA [H]

EC number: NA

Molecular weight: Translated: 11939; Mature: 11939

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMIREQIEEKLRTAFDPVFLEVVDESYRHNVPAGSESHFKVVLVSDRFTGERFLNRHRMI
CCCHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHCCEEE
YGTLTAELSTTVHALALHTYTLKEWEGLQDTIFASPPCRGAGSIA
EEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCC
>Mature Secondary Structure
MMIREQIEEKLRTAFDPVFLEVVDESYRHNVPAGSESHFKVVLVSDRFTGERFLNRHRMI
CCCHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHCCEEE
YGTLTAELSTTVHALALHTYTLKEWEGLQDTIFASPPCRGAGSIA
EEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]