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The map label for this gene is malZ [H]

Identifier: 16763781

GI number: 16763781

Start: 456184

End: 458001

Strand: Direct

Name: malZ [H]

Synonym: STM0401

Alternate gene names: 16763781

Gene position: 456184-458001 (Clockwise)

Preceding gene: 16763780

Following gene: 16763784

Centisome position: 9.39

GC content: 57.59

Gene sequence:

>1818_bases
ATGTTGAATGCCTGGCACTTACCGGTTGCCCCATTTGTGAAGCAACATAACGATAAATTAACCATTACGCTGTGGCTGAG
CGGAGAAAATCCGCCGTCTCGCGTGACGTTGCGCTCAGAATTCGATAATGAAGAAATCTCACTGGCGATGCGCAAACAGC
GCCGCCAGCCGCAGCCGGGCGTGACGGCGTGGCGAGCGACGCTCAATATCGCGTTAGGGCAACCCCGTCGCCGTTACAGC
TTTAAATTGCTTTGGCATGACCGCCAGCTTTGGTTTACGCCACAGGGATTTAGCCGTTTTCCGCCTGCGCGTCTGGAACA
ATTTGCGGTTGATGTGCCGGATAGCGGCCCGCAGTGGGTCGCCGATCAAATTTTTTATCAGATCTTCCCGGATCGTTTTG
CCCGCAGCCAGTCTCGTGAAGCCGGGCAGGACCGGGTGTACTACCATCATGCCGCAGGTCAGGAGATTGTGCTGCGCGAC
TGGGACGATCCTTTAACCCCCCAGGCGGGCGGTTCCACCTTTTACGGCGGCTGTCTGAATGGCATTTGTGAGAAGCTGCC
GTATCTGAAAAAACTGGGCGTCACAGCGCTATATCTGAATCCGGTATTTACCGCGCCGAGCGTCCATAAGTACGATACGG
AAGATTATCGCCATGTCGATCCGCAATTTGGCGGCGATCGGGCGCTGCTACGCCTGCGGCGTAAAACCCAGGTGCAGGGC
ATGAGGCTGGTGCTGGATGGCGTGTTTAATCATAGCGGCGACTCGCATGTGTGGTTTGACAGGCATAACCGCAGCACTGG
CGGCGCGTGCCATCACCCGGACTCGCCGTGGCGCGACTGGTACTCCTTTTCACCACAAGGCGTGGCGCTGGACTGGCTGG
GTTATCCGAGCCTGCCGAAACTCGATTATCAATCAGAAACGCTGGTCGATGAGATCTATCGCGGTGAGGACAGTATCGTT
CGTCACTGGCTAAAGGCTCCGTGGAATATGGACGGCTGGCGGCTGGATGTCGTACATATGCTGGGCGAGGCGGGCGGGGC
GCGTCATAATTTGCAGCACGTCGCCGGTATTACCCGGGCGGCAAAAGAGGCGCAGCCCGAAGCCTATATTGTGGGGGAAC
ATTTCGGCGATGCGCGGCAGTGGCTACAGGCCGATGCGGAAGATGCCGCCATGAATTATCGCGGCTTCACCTTCCCGCTA
TGGGGATTTCTCGCCAATACTGATATCGCTTACGAACCACAGCATATTGATGCCCGGACCTGTATCGCGTGGATGGATAA
CTACCGCGCCGGGCTGTCACATCAGCAACAACTGCGCATGTTTAATCAACTCGACAGCCATGATACTGCGCGCTTTAAAA
CTCTGCTGGGTAAAGACGCGGCGCGCCTGCCGCTGGCGGTGGTCTGGCTGTTTACCTGGCCCGGCGTGCCATGTATTTAT
TACGGCGATGAAGTCGGCGTGGACGGCGCAAATGACCCCATGTGCCGCAAACCGTTCCCATGGGATGAACGCAAGCAGGA
CGGCAACTTGCTGGCGCTGTACCAGCGTATGGCGAAACTGCGCCAGAGCAGTCTGGCGCTGCGTCGTGGCGGATGCCAGG
CGCTGTATGCCGAAGGTGACGTAGTGGTATTCGTGCGAGTTTATCAGCAGCAGCGGGCGCTGGTGGCGATTAACCGGGGC
GAGGCCTGTGAAGTGGCGCTGGAAGCGTTGCCGTTGCTGAACGTGGCCGGATGGCAATGTAAAACGGGAAGCGGTGATAT
CCGCGAGGGAAGACTTAGTTTACCCGCGATTTCCGCGACGGTATGGATGAATCGTTGA

Upstream 100 bases:

>100_bases
CTCCTCCTGGAGCCTCCTCCCCTAATAAACCCCTGGATGATGAGTTATCCTTTAAATCTCTGTGGCAAGGTGGCCCCATT
TTCAGTAGAGGGGATACGAG

Downstream 100 bases:

>100_bases
GGCGAGGTGGTTCGTAACACCTTACGCATAAAAAAGGCTCGCATTCGCGAGCCTTTTATCAATGCACTGACTTACAGGCT
GGAAATGTTCTCAGCCAGGT

Product: maltodextrin glucosidase

Products: NA

Alternate protein names: Alpha-glucosidase [H]

Number of amino acids: Translated: 605; Mature: 605

Protein sequence:

>605_residues
MLNAWHLPVAPFVKQHNDKLTITLWLSGENPPSRVTLRSEFDNEEISLAMRKQRRQPQPGVTAWRATLNIALGQPRRRYS
FKLLWHDRQLWFTPQGFSRFPPARLEQFAVDVPDSGPQWVADQIFYQIFPDRFARSQSREAGQDRVYYHHAAGQEIVLRD
WDDPLTPQAGGSTFYGGCLNGICEKLPYLKKLGVTALYLNPVFTAPSVHKYDTEDYRHVDPQFGGDRALLRLRRKTQVQG
MRLVLDGVFNHSGDSHVWFDRHNRSTGGACHHPDSPWRDWYSFSPQGVALDWLGYPSLPKLDYQSETLVDEIYRGEDSIV
RHWLKAPWNMDGWRLDVVHMLGEAGGARHNLQHVAGITRAAKEAQPEAYIVGEHFGDARQWLQADAEDAAMNYRGFTFPL
WGFLANTDIAYEPQHIDARTCIAWMDNYRAGLSHQQQLRMFNQLDSHDTARFKTLLGKDAARLPLAVVWLFTWPGVPCIY
YGDEVGVDGANDPMCRKPFPWDERKQDGNLLALYQRMAKLRQSSLALRRGGCQALYAEGDVVVFVRVYQQQRALVAINRG
EACEVALEALPLLNVAGWQCKTGSGDIREGRLSLPAISATVWMNR

Sequences:

>Translated_605_residues
MLNAWHLPVAPFVKQHNDKLTITLWLSGENPPSRVTLRSEFDNEEISLAMRKQRRQPQPGVTAWRATLNIALGQPRRRYS
FKLLWHDRQLWFTPQGFSRFPPARLEQFAVDVPDSGPQWVADQIFYQIFPDRFARSQSREAGQDRVYYHHAAGQEIVLRD
WDDPLTPQAGGSTFYGGCLNGICEKLPYLKKLGVTALYLNPVFTAPSVHKYDTEDYRHVDPQFGGDRALLRLRRKTQVQG
MRLVLDGVFNHSGDSHVWFDRHNRSTGGACHHPDSPWRDWYSFSPQGVALDWLGYPSLPKLDYQSETLVDEIYRGEDSIV
RHWLKAPWNMDGWRLDVVHMLGEAGGARHNLQHVAGITRAAKEAQPEAYIVGEHFGDARQWLQADAEDAAMNYRGFTFPL
WGFLANTDIAYEPQHIDARTCIAWMDNYRAGLSHQQQLRMFNQLDSHDTARFKTLLGKDAARLPLAVVWLFTWPGVPCIY
YGDEVGVDGANDPMCRKPFPWDERKQDGNLLALYQRMAKLRQSSLALRRGGCQALYAEGDVVVFVRVYQQQRALVAINRG
EACEVALEALPLLNVAGWQCKTGSGDIREGRLSLPAISATVWMNR
>Mature_605_residues
MLNAWHLPVAPFVKQHNDKLTITLWLSGENPPSRVTLRSEFDNEEISLAMRKQRRQPQPGVTAWRATLNIALGQPRRRYS
FKLLWHDRQLWFTPQGFSRFPPARLEQFAVDVPDSGPQWVADQIFYQIFPDRFARSQSREAGQDRVYYHHAAGQEIVLRD
WDDPLTPQAGGSTFYGGCLNGICEKLPYLKKLGVTALYLNPVFTAPSVHKYDTEDYRHVDPQFGGDRALLRLRRKTQVQG
MRLVLDGVFNHSGDSHVWFDRHNRSTGGACHHPDSPWRDWYSFSPQGVALDWLGYPSLPKLDYQSETLVDEIYRGEDSIV
RHWLKAPWNMDGWRLDVVHMLGEAGGARHNLQHVAGITRAAKEAQPEAYIVGEHFGDARQWLQADAEDAAMNYRGFTFPL
WGFLANTDIAYEPQHIDARTCIAWMDNYRAGLSHQQQLRMFNQLDSHDTARFKTLLGKDAARLPLAVVWLFTWPGVPCIY
YGDEVGVDGANDPMCRKPFPWDERKQDGNLLALYQRMAKLRQSSLALRRGGCQALYAEGDVVVFVRVYQQQRALVAINRG
EACEVALEALPLLNVAGWQCKTGSGDIREGRLSLPAISATVWMNR

Specific function: May play a role in regulating the intracellular level of maltotriose. Cleaves glucose from the reducing end of maltotriose and longer maltodextrins with a chain length of up to 7 glucose units [H]

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=489, Percent_Identity=22.9038854805726, Blast_Score=85, Evalue=2e-16,
Organism=Escherichia coli, GI1786604, Length=604, Percent_Identity=83.112582781457, Blast_Score=1055, Evalue=0.0,
Organism=Escherichia coli, GI1790687, Length=186, Percent_Identity=29.0322580645161, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6321726, Length=265, Percent_Identity=25.2830188679245, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322241, Length=265, Percent_Identity=24.5283018867925, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6322021, Length=265, Percent_Identity=24.5283018867925, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6324416, Length=265, Percent_Identity=24.5283018867925, Blast_Score=74, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6322245, Length=202, Percent_Identity=27.2277227722772, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321731, Length=176, Percent_Identity=27.8409090909091, Blast_Score=71, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6319776, Length=176, Percent_Identity=27.8409090909091, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24586593, Length=521, Percent_Identity=23.8003838771593, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24586599, Length=511, Percent_Identity=23.8747553816047, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24586597, Length=501, Percent_Identity=23.9520958083832, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45549022, Length=200, Percent_Identity=28.5, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24586587, Length=93, Percent_Identity=40.8602150537634, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24586589, Length=370, Percent_Identity=25.1351351351351, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24586591, Length=378, Percent_Identity=23.8095238095238, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI221330053, Length=112, Percent_Identity=33.0357142857143, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24583747, Length=86, Percent_Identity=39.5348837209302, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24583749, Length=86, Percent_Identity=39.5348837209302, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR004185
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR013783
- InterPro:   IPR014756
- InterPro:   IPR017069 [H]

Pfam domain/function: PF00128 Alpha-amylase; PF02903 Alpha-amylase_N [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 69057; Mature: 69057

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNAWHLPVAPFVKQHNDKLTITLWLSGENPPSRVTLRSEFDNEEISLAMRKQRRQPQPG
CCCCCCCCCHHHHHCCCCEEEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCC
VTAWRATLNIALGQPRRRYSFKLLWHDRQLWFTPQGFSRFPPARLEQFAVDVPDSGPQWV
CEEEEEEEEEEECCCCCCEEEEEEEECCEEEECCCCCCCCCHHHHHHHEECCCCCCCHHH
ADQIFYQIFPDRFARSQSREAGQDRVYYHHAAGQEIVLRDWDDPLTPQAGGSTFYGGCLN
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCCEEHHHHH
GICEKLPYLKKLGVTALYLNPVFTAPSVHKYDTEDYRHVDPQFGGDRALLRLRRKTQVQG
HHHHHCHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
MRLVLDGVFNHSGDSHVWFDRHNRSTGGACHHPDSPWRDWYSFSPQGVALDWLGYPSLPK
HHHEEHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEECCCCCCCC
LDYQSETLVDEIYRGEDSIVRHWLKAPWNMDGWRLDVVHMLGEAGGARHNLQHVAGITRA
CCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEHHHHHHHCCCCCHHHHHHHHHHHHH
AKEAQPEAYIVGEHFGDARQWLQADAEDAAMNYRGFTFPLWGFLANTDIAYEPQHIDART
HHHCCCCEEEEECCCCHHHHHHHCCCHHHHCCCCCCCCHHHHHHCCCCCEECCCCCCHHH
CIAWMDNYRAGLSHQQQLRMFNQLDSHDTARFKTLLGKDAARLPLAVVWLFTWPGVPCIY
HHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCHHCCEEEEEEECCCCCCEEE
YGDEVGVDGANDPMCRKPFPWDERKQDGNLLALYQRMAKLRQSSLALRRGGCQALYAEGD
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
VVVFVRVYQQQRALVAINRGEACEVALEALPLLNVAGWQCKTGSGDIREGRLSLPAISAT
EEEEEEEHHCCCEEEEECCCCHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCEEEEE
VWMNR
EEECC
>Mature Secondary Structure
MLNAWHLPVAPFVKQHNDKLTITLWLSGENPPSRVTLRSEFDNEEISLAMRKQRRQPQPG
CCCCCCCCCHHHHHCCCCEEEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCC
VTAWRATLNIALGQPRRRYSFKLLWHDRQLWFTPQGFSRFPPARLEQFAVDVPDSGPQWV
CEEEEEEEEEEECCCCCCEEEEEEEECCEEEECCCCCCCCCHHHHHHHEECCCCCCCHHH
ADQIFYQIFPDRFARSQSREAGQDRVYYHHAAGQEIVLRDWDDPLTPQAGGSTFYGGCLN
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCCEEHHHHH
GICEKLPYLKKLGVTALYLNPVFTAPSVHKYDTEDYRHVDPQFGGDRALLRLRRKTQVQG
HHHHHCHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
MRLVLDGVFNHSGDSHVWFDRHNRSTGGACHHPDSPWRDWYSFSPQGVALDWLGYPSLPK
HHHEEHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEECCCCCCCC
LDYQSETLVDEIYRGEDSIVRHWLKAPWNMDGWRLDVVHMLGEAGGARHNLQHVAGITRA
CCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEHHHHHHHCCCCCHHHHHHHHHHHHH
AKEAQPEAYIVGEHFGDARQWLQADAEDAAMNYRGFTFPLWGFLANTDIAYEPQHIDART
HHHCCCCEEEEECCCCHHHHHHHCCCHHHHCCCCCCCCHHHHHHCCCCCEECCCCCCHHH
CIAWMDNYRAGLSHQQQLRMFNQLDSHDTARFKTLLGKDAARLPLAVVWLFTWPGVPCIY
HHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCHHCCEEEEEEECCCCCCEEE
YGDEVGVDGANDPMCRKPFPWDERKQDGNLLALYQRMAKLRQSSLALRRGGCQALYAEGD
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
VVVFVRVYQQQRALVAINRGEACEVALEALPLLNVAGWQCKTGSGDIREGRLSLPAISAT
EEEEEEEHHCCCEEEEECCCCHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCEEEEE
VWMNR
EEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1918057; 9278503; 1706703 [H]