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The map label for this gene is foxA

Identifier: 16763744

GI number: 16763744

Start: 412663

End: 414771

Strand: Direct

Name: foxA

Synonym: STM0364

Alternate gene names: 16763744

Gene position: 412663-414771 (Clockwise)

Preceding gene: 16763743

Following gene: 16763746

Centisome position: 8.5

GC content: 52.73

Gene sequence:

>2109_bases
ATGCCTTTGGAGATGTTCATGTTTGCGACAACGCGTATGGCGCTATTGATAGGCGGAGCTATCGGCGGCGCGACTTTTCC
TCTTTTTGCCCAGGAAACCACAAAAAATGATACCGTCATTGTCACCTCGCCCGTTCAGAGTGGCGCGACCAAGCTGGCGA
CGCCAGATATTGAAACGCCGCAGTCGGTATCCATTATTACCCGCCAGCAGTTTGAAGAGCAGGGCGCAACCAGCGTGCGT
CAGGCGGTCAGCTACACCCCAGGCGTATACAGTAACCAGATAGGCGCCTCTAACCGCTTTGATTACATCGTATTGCGTGG
TTTTTCGGACGGTAGTCTGGATAACGTCTATCTCGACGGGTTAAAAATGATGGGCGACACCAATTCGCACAGTTCGTTGG
TGGTTGACCCCTGGTTTCTGGAAGATATCGAGGTGGTACGCGGCCCGGCGTCCGTTCTGTATGGACGTTCATCGCCAGGC
GGCATTGTCGCGCTGACGTCGCGAAAACCGGCGTTTGATGCCGGAGGAGAAGTGAAGCTGTTTGCCGGCAATAACAACCA
GCGCGGGGCGGCTTTTGATGTGACCGGCCCACTGGATGACAATGAACGTGTGGCGGCGCGTCTTAGCGGCATGACACGTT
ACGCCGATTCGCAGTTTACCCCCTTGAAAGAGGAACGTTATGCGCTGATGCCGAGCCTGACCTGGCGAATTACCGATCGG
ACGCGTCTTGATCTTATGGCCTATCCGCACCGTGATCCGGAAGGCGGTAGCCACTCCGGACTGCCTTATCAAGGCACGGT
TGTACCTTATAACGGCGGAAAAATTTCTAACACTTTCTTTGAAGGTGAAGATGACTACGACAAATACGATCGCCGTGAAA
ATATGGTGGGTTATAACATTGAGCATCTGTTCGATAACGGCTGGTCGGTACGGCAAAAATTGCGCTATTTGCATACCAAA
GTGACGTTGAATCAGGTCTATGCCGCAGGTTGGTTGAATGAAACGGCGCTGAATCGCGGCTATTCCGGCTCCGGGGAGAA
AATGTCGGCTATCGCGCTGGATAATCAGCTCGACGGCAGCGTGGATACCGGGGCGATTAATCATCGTCTGCTGGTGGGGA
TCGATTATCAGGATCGCAGTAACCATACTACTGGCTATTATGGCGCGTTTCCGCCGATTGACGCTTTCAACCCTGTTTAT
GGCGCTCAGCCGGATTACATTACGTTGTATAGCCGTGAAAAACATAAGCTGCGGCAGACCGGATACTATTTACAGGATCA
GATGTCATGGGATCGCTGGCGCTTTACGTTGGGCGGTCGTTACGATCGGGTCAGCGTGTCTAACATCGACAAACTTCATG
ATTCACGCAGCGATCTCGATAAAAACAACGTCAGTACCCGTGCTGCGTTGCTTTATCTGTTCGACAATGGCGTCGCCCCC
TATCTCAGTTATTCTACCGCGTTTACGCCGACCAGCTTCGCCGACGAAAACGGCAATGTGCTGGAACCGATGAAAGGCAA
GCAGTGGGAGGCGGGGGTAAAATACGAACCGCCGGGGGGGAATAGCCAGTTTAGCGCCGCCGTGTATCGTATTAATCAGA
CCAATATCGCGACCAAAGAAGAACCTACCGATCCGTACCGCTCGATTGGTGAAATTGAGTCTAAAGGGGTTGAACTGGAG
GCCATTAGCCATTTGTCGGATAGCGTCCGTTTGCAGGCGGCGTATACCTATACTGATATCCGTTATAAGAAAAGTAGCCC
GCAAGAACAGGGTAAGCGCGCGGTTTATGCTCCACGGAACCAGGCCAGCGCCTGGCTAAGCTACGATGTGAAAAGCGGTC
TGTTAGAGGGGCTGACTTTGGGCTCCGGCATCCGGTACGTCAACGGCGTGACCAGCGATCGCCTGAATACCCACACATTG
CCGTCCTATACACTGGTCGATATGGTGGTAGGGTATGATTTATCCAGCATTGGGTTAAATGGCTTGAGCGCCCAGCTCAA
CGTAAATAACCTGACGGACAAACGCTATGTCGCTGCCTGTAATTCGCTCTCTTATTGTTATTTTGGCGCCGAGCGTAGCA
TTGTAGGCAGCGTGTCATGGGCGTTTTGA

Upstream 100 bases:

>100_bases
GCCGCTTTGGGTGATTTTTTATCATTGCGCATAGGCAATCTGGCGTTACGCATAGTGGTCCGTCATCTCTAAAAGGTAAT
AATTCTTATTTACAATAAAG

Downstream 100 bases:

>100_bases
TAACGCTTATCGTCCGGTAGCAAAGGCTACCGGACAAACATTAGCGGTGCGTCACGCCTTCATAGAGAAGTCTGAGCGCA
AACATCCCGATAATGGCGCC

Product: ferrioxamine receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 702; Mature: 701

Protein sequence:

>702_residues
MPLEMFMFATTRMALLIGGAIGGATFPLFAQETTKNDTVIVTSPVQSGATKLATPDIETPQSVSIITRQQFEEQGATSVR
QAVSYTPGVYSNQIGASNRFDYIVLRGFSDGSLDNVYLDGLKMMGDTNSHSSLVVDPWFLEDIEVVRGPASVLYGRSSPG
GIVALTSRKPAFDAGGEVKLFAGNNNQRGAAFDVTGPLDDNERVAARLSGMTRYADSQFTPLKEERYALMPSLTWRITDR
TRLDLMAYPHRDPEGGSHSGLPYQGTVVPYNGGKISNTFFEGEDDYDKYDRRENMVGYNIEHLFDNGWSVRQKLRYLHTK
VTLNQVYAAGWLNETALNRGYSGSGEKMSAIALDNQLDGSVDTGAINHRLLVGIDYQDRSNHTTGYYGAFPPIDAFNPVY
GAQPDYITLYSREKHKLRQTGYYLQDQMSWDRWRFTLGGRYDRVSVSNIDKLHDSRSDLDKNNVSTRAALLYLFDNGVAP
YLSYSTAFTPTSFADENGNVLEPMKGKQWEAGVKYEPPGGNSQFSAAVYRINQTNIATKEEPTDPYRSIGEIESKGVELE
AISHLSDSVRLQAAYTYTDIRYKKSSPQEQGKRAVYAPRNQASAWLSYDVKSGLLEGLTLGSGIRYVNGVTSDRLNTHTL
PSYTLVDMVVGYDLSSIGLNGLSAQLNVNNLTDKRYVAACNSLSYCYFGAERSIVGSVSWAF

Sequences:

>Translated_702_residues
MPLEMFMFATTRMALLIGGAIGGATFPLFAQETTKNDTVIVTSPVQSGATKLATPDIETPQSVSIITRQQFEEQGATSVR
QAVSYTPGVYSNQIGASNRFDYIVLRGFSDGSLDNVYLDGLKMMGDTNSHSSLVVDPWFLEDIEVVRGPASVLYGRSSPG
GIVALTSRKPAFDAGGEVKLFAGNNNQRGAAFDVTGPLDDNERVAARLSGMTRYADSQFTPLKEERYALMPSLTWRITDR
TRLDLMAYPHRDPEGGSHSGLPYQGTVVPYNGGKISNTFFEGEDDYDKYDRRENMVGYNIEHLFDNGWSVRQKLRYLHTK
VTLNQVYAAGWLNETALNRGYSGSGEKMSAIALDNQLDGSVDTGAINHRLLVGIDYQDRSNHTTGYYGAFPPIDAFNPVY
GAQPDYITLYSREKHKLRQTGYYLQDQMSWDRWRFTLGGRYDRVSVSNIDKLHDSRSDLDKNNVSTRAALLYLFDNGVAP
YLSYSTAFTPTSFADENGNVLEPMKGKQWEAGVKYEPPGGNSQFSAAVYRINQTNIATKEEPTDPYRSIGEIESKGVELE
AISHLSDSVRLQAAYTYTDIRYKKSSPQEQGKRAVYAPRNQASAWLSYDVKSGLLEGLTLGSGIRYVNGVTSDRLNTHTL
PSYTLVDMVVGYDLSSIGLNGLSAQLNVNNLTDKRYVAACNSLSYCYFGAERSIVGSVSWAF
>Mature_701_residues
PLEMFMFATTRMALLIGGAIGGATFPLFAQETTKNDTVIVTSPVQSGATKLATPDIETPQSVSIITRQQFEEQGATSVRQ
AVSYTPGVYSNQIGASNRFDYIVLRGFSDGSLDNVYLDGLKMMGDTNSHSSLVVDPWFLEDIEVVRGPASVLYGRSSPGG
IVALTSRKPAFDAGGEVKLFAGNNNQRGAAFDVTGPLDDNERVAARLSGMTRYADSQFTPLKEERYALMPSLTWRITDRT
RLDLMAYPHRDPEGGSHSGLPYQGTVVPYNGGKISNTFFEGEDDYDKYDRRENMVGYNIEHLFDNGWSVRQKLRYLHTKV
TLNQVYAAGWLNETALNRGYSGSGEKMSAIALDNQLDGSVDTGAINHRLLVGIDYQDRSNHTTGYYGAFPPIDAFNPVYG
AQPDYITLYSREKHKLRQTGYYLQDQMSWDRWRFTLGGRYDRVSVSNIDKLHDSRSDLDKNNVSTRAALLYLFDNGVAPY
LSYSTAFTPTSFADENGNVLEPMKGKQWEAGVKYEPPGGNSQFSAAVYRINQTNIATKEEPTDPYRSIGEIESKGVELEA
ISHLSDSVRLQAAYTYTDIRYKKSSPQEQGKRAVYAPRNQASAWLSYDVKSGLLEGLTLGSGIRYVNGVTSDRLNTHTLP
SYTLVDMVVGYDLSSIGLNGLSAQLNVNNLTDKRYVAACNSLSYCYFGAERSIVGSVSWAF

Specific function: Ferrioxamine binding and uptake, in association with the tonB protein. May play a role in intestinal colonization

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family

Homologues:

Organism=Escherichia coli, GI1786344, Length=738, Percent_Identity=36.449864498645, Blast_Score=447, Evalue=1e-127,
Organism=Escherichia coli, GI1787024, Length=775, Percent_Identity=24.258064516129, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1787344, Length=723, Percent_Identity=24.896265560166, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI1790743, Length=656, Percent_Identity=21.7987804878049, Blast_Score=80, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FOXA_SALTY (Q56145)

Other databases:

- EMBL:   AE006468
- EMBL:   AF060876
- EMBL:   U62282
- RefSeq:   NP_459359.1
- ProteinModelPortal:   Q56145
- GeneID:   1251883
- GenomeReviews:   AE006468_GR
- KEGG:   stm:STM0364
- NMPDR:   fig|99287.1.peg.350
- HOGENOM:   HBG564417
- OMA:   VGASNRY
- ProtClustDB:   CLSK893954
- BioCyc:   STYP99287:STM0364-MONOMER
- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010105
- Gene3D:   G3DSA:2.170.130.10
- Gene3D:   G3DSA:2.40.170.20
- TIGRFAMs:   TIGR01783

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec

EC number: NA

Molecular weight: Translated: 77686; Mature: 77555

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS00430 TONB_DEPENDENT_REC_1; PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLEMFMFATTRMALLIGGAIGGATFPLFAQETTKNDTVIVTSPVQSGATKLATPDIETP
CCCEEHHHHHHHEEHHEECCCCCCCCEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCC
QSVSIITRQQFEEQGATSVRQAVSYTPGVYSNQIGASNRFDYIVLRGFSDGSLDNVYLDG
CCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEECC
LKMMGDTNSHSSLVVDPWFLEDIEVVRGPASVLYGRSSPGGIVALTSRKPAFDAGGEVKL
EEEECCCCCCCEEEECCHHHHHHHHHCCCHHHEECCCCCCCEEEECCCCCCCCCCCCEEE
FAGNNNQRGAAFDVTGPLDDNERVAARLSGMTRYADSQFTPLKEERYALMPSLTWRITDR
EECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHEEECCCEEEEECCC
TRLDLMAYPHRDPEGGSHSGLPYQGTVVPYNGGKISNTFFEGEDDYDKYDRRENMVGYNI
CEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCEEECCEECCCCCHHHHHHHCCCCCCCH
EHLFDNGWSVRQKLRYLHTKVTLNQVYAAGWLNETALNRGYSGSGEKMSAIALDNQLDGS
HHHHCCCHHHHHHHHHHHHHEEHHHHHHHCCCCHHHHCCCCCCCCCEEEEEEECCCCCCC
VDTGAINHRLLVGIDYQDRSNHTTGYYGAFPPIDAFNPVYGAQPDYITLYSREKHKLRQT
CCCCCCCCEEEEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHC
GYYLQDQMSWDRWRFTLGGRYDRVSVSNIDKLHDSRSDLDKNNVSTRAALLYLFDNGVAP
CCEEHHCCCCCCEEEEECCCCCEEEHHHHHHHHCCHHHCCCCCCCCEEEEEEEECCCCCC
YLSYSTAFTPTSFADENGNVLEPMKGKQWEAGVKYEPPGGNSQFSAAVYRINQTNIATKE
CEECCCCCCCCCCCCCCCCEECCCCCCCCCCCCEECCCCCCCCEEEEEEEEECCCCCCCC
EPTDPYRSIGEIESKGVELEAISHLSDSVRLQAAYTYTDIRYKKSSPQEQGKRAVYAPRN
CCCCHHHHHHHHHHCCEEEEHHHHCCCCEEEEEEEEEEEEEECCCCCHHHCCEEEECCCC
QASAWLSYDVKSGLLEGLTLGSGIRYVNGVTSDRLNTHTLPSYTLVDMVVGYDLSSIGLN
CCCEEEEECHHHHHHHHEECCCCCCEECCCCCCCCCCCCCCCHHHHHHHHCCCHHHCCCC
GLSAQLNVNNLTDKRYVAACNSLSYCYFGAERSIVGSVSWAF
CEEEEEECCCCCCCHHHHHHCCCEEEEECCCCCEEEEEEECC
>Mature Secondary Structure 
PLEMFMFATTRMALLIGGAIGGATFPLFAQETTKNDTVIVTSPVQSGATKLATPDIETP
CCEEHHHHHHHEEHHEECCCCCCCCEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCCC
QSVSIITRQQFEEQGATSVRQAVSYTPGVYSNQIGASNRFDYIVLRGFSDGSLDNVYLDG
CCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEECC
LKMMGDTNSHSSLVVDPWFLEDIEVVRGPASVLYGRSSPGGIVALTSRKPAFDAGGEVKL
EEEECCCCCCCEEEECCHHHHHHHHHCCCHHHEECCCCCCCEEEECCCCCCCCCCCCEEE
FAGNNNQRGAAFDVTGPLDDNERVAARLSGMTRYADSQFTPLKEERYALMPSLTWRITDR
EECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHEEECCCEEEEECCC
TRLDLMAYPHRDPEGGSHSGLPYQGTVVPYNGGKISNTFFEGEDDYDKYDRRENMVGYNI
CEEEEEECCCCCCCCCCCCCCCCCCEEEEECCCEEECCEECCCCCHHHHHHHCCCCCCCH
EHLFDNGWSVRQKLRYLHTKVTLNQVYAAGWLNETALNRGYSGSGEKMSAIALDNQLDGS
HHHHCCCHHHHHHHHHHHHHEEHHHHHHHCCCCHHHHCCCCCCCCCEEEEEEECCCCCCC
VDTGAINHRLLVGIDYQDRSNHTTGYYGAFPPIDAFNPVYGAQPDYITLYSREKHKLRQT
CCCCCCCCEEEEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHC
GYYLQDQMSWDRWRFTLGGRYDRVSVSNIDKLHDSRSDLDKNNVSTRAALLYLFDNGVAP
CCEEHHCCCCCCEEEEECCCCCEEEHHHHHHHHCCHHHCCCCCCCCEEEEEEEECCCCCC
YLSYSTAFTPTSFADENGNVLEPMKGKQWEAGVKYEPPGGNSQFSAAVYRINQTNIATKE
CEECCCCCCCCCCCCCCCCEECCCCCCCCCCCCEECCCCCCCCEEEEEEEEECCCCCCCC
EPTDPYRSIGEIESKGVELEAISHLSDSVRLQAAYTYTDIRYKKSSPQEQGKRAVYAPRN
CCCCHHHHHHHHHHCCEEEEHHHHCCCCEEEEEEEEEEEEEECCCCCHHHCCEEEECCCC
QASAWLSYDVKSGLLEGLTLGSGIRYVNGVTSDRLNTHTLPSYTLVDMVVGYDLSSIGLN
CCCEEEEECHHHHHHHHEECCCCCCEECCCCCCCCCCCCCCCHHHHHHHHCCCHHHCCCC
GLSAQLNVNNLTDKRYVAACNSLSYCYFGAERSIVGSVSWAF
CEEEEEECCCCCCCHHHHHHCCCEEEEECCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677609; 10103258; 7642488