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The map label for this gene is rtn [H]

Identifier: 16763723

GI number: 16763723

Start: 387109

End: 388683

Strand: Direct

Name: rtn [H]

Synonym: STM0343

Alternate gene names: 16763723

Gene position: 387109-388683 (Clockwise)

Preceding gene: 16763722

Following gene: 16763724

Centisome position: 7.97

GC content: 48.44

Gene sequence:

>1575_bases
TTGAAAGTAAGAAAGCTATTTCTGATGTTGTTTATTGCCGTTCCACTGATCGTAATGATATTGGTGGGGTTACTCGCGGG
TATCTTCCAGCTAAAACGAGATATCGCCGTCAGCGCCAATACGCTGCTGCGGTTTAGCGCGGATATATCCGCCGCCTCCT
GGCAAGTCGCCGGAAAAGCCGCCAGACTGGCTGAGAGTTCCTGCACTGACACGCTGAAAGAACTGTCCAGAACGCGGGCC
TTCACTCCTTATGTCCGTGACATTGGATTTCTGGAAAATGGTGATATCACTTGCTCCTTTGTCACAGGAACCGAACGCTA
TCATTTTTCCCGGCTGGCAGGGCTTTCTTTACCTGCTTCTTATCCGGAACGGTGGTTGCGATCTATCGGTAGTATGGCCG
AAGGACCCGATCGCCTTGTTGTGGTGTATGTGAAAAAAGTAGCAGCGGATAAAGCGGCTTTCGTCATTGTGGATTCGCAG
TATGTCCAGGAGCTCATGGAGATATTGGCTGCAGAAAGAGCATCAGCCTTTAGCCTGACATTCGGCGCAGGAGAGGCGAT
TACCAGCGCTGCGAAGTTGCGCGGTAAGGCGTTTTTAACGCAGCGGTTCACCTCAACCGATCACACTATCCAGCTGATGG
TGCGAACCCCTTTCTCAACGTTATCGGCATACTGGTTACAAAACCTTTTTATTTTTATTCCGCTGTCATTGTGTCTTTCT
GTAGGGATGATGTTGTTCTACAGGCGCTGGTATTTAAAACGCTTATCTCTGGCCCGGGAGATTGCCAGGGGAATAACGCA
CAATGAATTTACGGTACATTATCAACCTGTTTTTAATGTTAAACACGGTAGTTGCGGCGGCGTGGAGGCGCTAATGCGCT
GGCCGCAACCGGATGGCCGTTTTATAACTCCCGATATTTTTATTACCGCCGCAGAAAATGAAGGCATGATTATTCCACTC
TCTCGTCATCTGTTCGAACTGATTGCTCATGACGTGATAAACTGGACTGTACCGGATGATTTCTATATCAGCGTAAATAT
ATCGCCTGCGCATCTTATGGATGACGGTTTTATACAAGATATAGAGGCGCTCAGGACTCGTTTGGGAACGATAACGCTTA
TGTTGGAGCTCACCGAACGTAGCCTGATTGTAGAACCTTCACAGGTCGCAGAAAAACTTTCAACGCTCCGTGAAAAAGGC
GTGTTAATAGCGATTGATGATTTTGGGACCGGCTATTGCTCCCTCTCCTATCTCCAGCAATTACCTGTAGACTCTCTTAA
AATAGACAGAACGTTTATCGATACCATTGATACCAGCAGCGATGATGTTCCTGTCCTGGATACTATCATTACGCTGAGTC
AGCGACTGGGACTCAATGTGGTTGCCGAAGGGGTCAGTACCCAGCACCAATTGCGTTACATCTTAAGCCACGGGGTAGGA
TTCGTTCAGGGATTTCTTTATGCCAGGCCGATGGGGACTAATGACTTTATGAGTTGGCTTGGCAAGTCAGCCCAGCGGCA
AAATGGTTTGCTCAAGGGGGAAAGCGGATCCGCGAGCGATCTGGTGGCTGAATAA

Upstream 100 bases:

>100_bases
ATAACCTATCTCTCAATATTGCTTTTCTATATTAATGTTACTTTAGTTATCCTATCAAAGCGTACAGTGGCAAAAGGAAG
GCCGGTAAGAGGGCAATGAT

Downstream 100 bases:

>100_bases
TGCAGGAACTCGCTACGGAAAAAAATTCAATAGCACGATATATCCTGGTAATATGTTTATGCCGTGAAGAAACGTGATAG
CACTGGGGCGGATATTTTTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 524; Mature: 524

Protein sequence:

>524_residues
MKVRKLFLMLFIAVPLIVMILVGLLAGIFQLKRDIAVSANTLLRFSADISAASWQVAGKAARLAESSCTDTLKELSRTRA
FTPYVRDIGFLENGDITCSFVTGTERYHFSRLAGLSLPASYPERWLRSIGSMAEGPDRLVVVYVKKVAADKAAFVIVDSQ
YVQELMEILAAERASAFSLTFGAGEAITSAAKLRGKAFLTQRFTSTDHTIQLMVRTPFSTLSAYWLQNLFIFIPLSLCLS
VGMMLFYRRWYLKRLSLAREIARGITHNEFTVHYQPVFNVKHGSCGGVEALMRWPQPDGRFITPDIFITAAENEGMIIPL
SRHLFELIAHDVINWTVPDDFYISVNISPAHLMDDGFIQDIEALRTRLGTITLMLELTERSLIVEPSQVAEKLSTLREKG
VLIAIDDFGTGYCSLSYLQQLPVDSLKIDRTFIDTIDTSSDDVPVLDTIITLSQRLGLNVVAEGVSTQHQLRYILSHGVG
FVQGFLYARPMGTNDFMSWLGKSAQRQNGLLKGESGSASDLVAE

Sequences:

>Translated_524_residues
MKVRKLFLMLFIAVPLIVMILVGLLAGIFQLKRDIAVSANTLLRFSADISAASWQVAGKAARLAESSCTDTLKELSRTRA
FTPYVRDIGFLENGDITCSFVTGTERYHFSRLAGLSLPASYPERWLRSIGSMAEGPDRLVVVYVKKVAADKAAFVIVDSQ
YVQELMEILAAERASAFSLTFGAGEAITSAAKLRGKAFLTQRFTSTDHTIQLMVRTPFSTLSAYWLQNLFIFIPLSLCLS
VGMMLFYRRWYLKRLSLAREIARGITHNEFTVHYQPVFNVKHGSCGGVEALMRWPQPDGRFITPDIFITAAENEGMIIPL
SRHLFELIAHDVINWTVPDDFYISVNISPAHLMDDGFIQDIEALRTRLGTITLMLELTERSLIVEPSQVAEKLSTLREKG
VLIAIDDFGTGYCSLSYLQQLPVDSLKIDRTFIDTIDTSSDDVPVLDTIITLSQRLGLNVVAEGVSTQHQLRYILSHGVG
FVQGFLYARPMGTNDFMSWLGKSAQRQNGLLKGESGSASDLVAE
>Mature_524_residues
MKVRKLFLMLFIAVPLIVMILVGLLAGIFQLKRDIAVSANTLLRFSADISAASWQVAGKAARLAESSCTDTLKELSRTRA
FTPYVRDIGFLENGDITCSFVTGTERYHFSRLAGLSLPASYPERWLRSIGSMAEGPDRLVVVYVKKVAADKAAFVIVDSQ
YVQELMEILAAERASAFSLTFGAGEAITSAAKLRGKAFLTQRFTSTDHTIQLMVRTPFSTLSAYWLQNLFIFIPLSLCLS
VGMMLFYRRWYLKRLSLAREIARGITHNEFTVHYQPVFNVKHGSCGGVEALMRWPQPDGRFITPDIFITAAENEGMIIPL
SRHLFELIAHDVINWTVPDDFYISVNISPAHLMDDGFIQDIEALRTRLGTITLMLELTERSLIVEPSQVAEKLSTLREKG
VLIAIDDFGTGYCSLSYLQQLPVDSLKIDRTFIDTIDTSSDDVPVLDTIITLSQRLGLNVVAEGVSTQHQLRYILSHGVG
FVQGFLYARPMGTNDFMSWLGKSAQRQNGLLKGESGSASDLVAE

Specific function: Involved in resistance to phages N4 and lambda [H]

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1788502, Length=518, Percent_Identity=30.1158301158301, Blast_Score=201, Evalue=7e-53,
Organism=Escherichia coli, GI87081845, Length=478, Percent_Identity=28.4518828451883, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI87081980, Length=456, Percent_Identity=30.2631578947368, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI87081743, Length=539, Percent_Identity=28.2003710575139, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI1786507, Length=250, Percent_Identity=36.8, Blast_Score=169, Evalue=5e-43,
Organism=Escherichia coli, GI1790496, Length=327, Percent_Identity=29.9694189602446, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI226510982, Length=250, Percent_Identity=34.8, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1787541, Length=255, Percent_Identity=30.1960784313725, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI87081921, Length=252, Percent_Identity=29.7619047619048, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI1787055, Length=249, Percent_Identity=30.5220883534137, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1788849, Length=254, Percent_Identity=27.9527559055118, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI87082096, Length=250, Percent_Identity=29.2, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1787410, Length=155, Percent_Identity=28.3870967741935, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 58279; Mature: 58279

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS00136 SUBTILASE_ASP ; PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVRKLFLMLFIAVPLIVMILVGLLAGIFQLKRDIAVSANTLLRFSADISAASWQVAGKA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHEEEECCCCCCHHHHHHHH
ARLAESSCTDTLKELSRTRAFTPYVRDIGFLENGDITCSFVTGTERYHFSRLAGLSLPAS
HHHHHHHHHHHHHHHHHHCCCCCHHHHCCCEECCCEEEEEEECCCHHHHHHHHCCCCCCC
YPERWLRSIGSMAEGPDRLVVVYVKKVAADKAAFVIVDSQYVQELMEILAAERASAFSLT
HHHHHHHHHCCCCCCCCCEEEEEEEHHCCCCEEEEEECHHHHHHHHHHHHHCCCCEEEEE
FGAGEAITSAAKLRGKAFLTQRFTSTDHTIQLMVRTPFSTLSAYWLQNLFIFIPLSLCLS
ECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
VGMMLFYRRWYLKRLSLAREIARGITHNEFTVHYQPVFNVKHGSCGGVEALMRWPQPDGR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCHHHHHHCCCCCCC
FITPDIFITAAENEGMIIPLSRHLFELIAHDVINWTVPDDFYISVNISPAHLMDDGFIQD
EECCEEEEEEECCCCEEEEHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHCCCHHHHH
IEALRTRLGTITLMLELTERSLIVEPSQVAEKLSTLREKGVLIAIDDFGTGYCSLSYLQQ
HHHHHHHHHHEEEEEEECCCCEEECHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHH
LPVDSLKIDRTFIDTIDTSSDDVPVLDTIITLSQRLGLNVVAEGVSTQHQLRYILSHGVG
CCCCCEEECHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHCHH
FVQGFLYARPMGTNDFMSWLGKSAQRQNGLLKGESGSASDLVAE
HHHHHHHCCCCCCHHHHHHHCCHHHHHCCCEECCCCCCCCCCCC
>Mature Secondary Structure
MKVRKLFLMLFIAVPLIVMILVGLLAGIFQLKRDIAVSANTLLRFSADISAASWQVAGKA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHEEEECCCCCCHHHHHHHH
ARLAESSCTDTLKELSRTRAFTPYVRDIGFLENGDITCSFVTGTERYHFSRLAGLSLPAS
HHHHHHHHHHHHHHHHHHCCCCCHHHHCCCEECCCEEEEEEECCCHHHHHHHHCCCCCCC
YPERWLRSIGSMAEGPDRLVVVYVKKVAADKAAFVIVDSQYVQELMEILAAERASAFSLT
HHHHHHHHHCCCCCCCCCEEEEEEEHHCCCCEEEEEECHHHHHHHHHHHHHCCCCEEEEE
FGAGEAITSAAKLRGKAFLTQRFTSTDHTIQLMVRTPFSTLSAYWLQNLFIFIPLSLCLS
ECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
VGMMLFYRRWYLKRLSLAREIARGITHNEFTVHYQPVFNVKHGSCGGVEALMRWPQPDGR
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCHHHHHHCCCCCCC
FITPDIFITAAENEGMIIPLSRHLFELIAHDVINWTVPDDFYISVNISPAHLMDDGFIQD
EECCEEEEEEECCCCEEEEHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHCCCHHHHH
IEALRTRLGTITLMLELTERSLIVEPSQVAEKLSTLREKGVLIAIDDFGTGYCSLSYLQQ
HHHHHHHHHHEEEEEEECCCCEEECHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHH
LPVDSLKIDRTFIDTIDTSSDDVPVLDTIITLSQRLGLNVVAEGVSTQHQLRYILSHGVG
CCCCCEEECHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHCHH
FVQGFLYARPMGTNDFMSWLGKSAQRQNGLLKGESGSASDLVAE
HHHHHHHCCCCCCHHHHHHHCCHHHHHCCCEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9079933 [H]