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The map label for this gene is ttdR [H]

Identifier: 16763713

GI number: 16763713

Start: 376663

End: 377628

Strand: Direct

Name: ttdR [H]

Synonym: STM0333

Alternate gene names: 16763713

Gene position: 376663-377628 (Clockwise)

Preceding gene: 16763712

Following gene: 16763715

Centisome position: 7.75

GC content: 49.07

Gene sequence:

>966_bases
ATGAAAACGACACCTGTAGGAAAAAAACATCGCCAGCCCCTTGAGGGCTGGCCTTCTGTTGAAGATCTTTTCGTTTTTGT
CACCGTTGCTCGCAACGGTGGATTTGCCCGGGCAGCGCTGGAGCTGGGGTTATCTCCCTCCTATATCAGCAAACGTATCG
CTATCCTTGAAAAATGTCTCAACGCCCGGCTTTTTTTTCGAAATAACAGAGTGATGCGTCTCACACCGGAAGGCGAAAAT
GCGCTGGGTGGGGCTATGCAGGTCGTCAGTGAAATGGATGGCTTTGTCAGTCGTTTGGATAATCAACGTGGTGTGTTGGC
TGGTAATATCACCATCAACTGCTCATTTGGTTTTGGGCATAAATATGTCGCAGAGGCGCTGTCGTCATTTATGATCGCCT
ATCCTGATATTACGGTAAAACTCACGCTAACGGATCGTGAAGTGGATCTGGTGGAAGAGGGGATCGATATTGAAATTCGC
GTTGGGGATGATATCAACGAATTGTATATCGCACGGCAGTTAGCCACTAATCGACGGATCCTGTGTGCTTCCCCTGAATA
CCTCGAACGCCACGGCAAGCCAGAGTCTGTTAGTGCGCTTGTGCAGCACGATTGCCTAATGATTCAGGAAAAAAACTCGG
CATTTGGCAATTGGATATTAACGGACGGTAAGCAGCAGACACATTGCCGACTAAACGGTTTTCATTCTTCCAACAGCGGC
AGTGTGGTGCTTATTTGGGCCCTGAAAGGCCATGGCATTACATTGCGGTCGGAATGGGATGTTGCGCAGTATATTGAACG
AGGTGAGCTGGTTCGCGTGTTGCCTCAGTGGTATCAGGAAGCGAATATCTGGGCTGTATATACCCGGCGTTCATCAAGTT
CTGATCGTATCAAAATCTGCATCGATTTCCTCACGGAGCATCTTGCACAATGCTTGCCAGGCGGTAAAGCACCGGGCGTA
CTGTGA

Upstream 100 bases:

>100_bases
CCCGCAGGAAGAGTGTCCTGAGTACTTTATCCAGAAACTTCAGTCCTTTTTACATTCAGTGTTATAACTCGGTCATCCTT
TGCAACTTCGCACTGATGCT

Downstream 100 bases:

>100_bases
TCAGTCGGCGCCAACTGTCGTGGCGCCAGATGCTCTGACTTACGTTTACTGTTAGGTGTTCTTTTTGCCAGCACCCAGTA
GCTTTTAGGGCGTTGCGTTG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MKTTPVGKKHRQPLEGWPSVEDLFVFVTVARNGGFARAALELGLSPSYISKRIAILEKCLNARLFFRNNRVMRLTPEGEN
ALGGAMQVVSEMDGFVSRLDNQRGVLAGNITINCSFGFGHKYVAEALSSFMIAYPDITVKLTLTDREVDLVEEGIDIEIR
VGDDINELYIARQLATNRRILCASPEYLERHGKPESVSALVQHDCLMIQEKNSAFGNWILTDGKQQTHCRLNGFHSSNSG
SVVLIWALKGHGITLRSEWDVAQYIERGELVRVLPQWYQEANIWAVYTRRSSSSDRIKICIDFLTEHLAQCLPGGKAPGV
L

Sequences:

>Translated_321_residues
MKTTPVGKKHRQPLEGWPSVEDLFVFVTVARNGGFARAALELGLSPSYISKRIAILEKCLNARLFFRNNRVMRLTPEGEN
ALGGAMQVVSEMDGFVSRLDNQRGVLAGNITINCSFGFGHKYVAEALSSFMIAYPDITVKLTLTDREVDLVEEGIDIEIR
VGDDINELYIARQLATNRRILCASPEYLERHGKPESVSALVQHDCLMIQEKNSAFGNWILTDGKQQTHCRLNGFHSSNSG
SVVLIWALKGHGITLRSEWDVAQYIERGELVRVLPQWYQEANIWAVYTRRSSSSDRIKICIDFLTEHLAQCLPGGKAPGV
L
>Mature_321_residues
MKTTPVGKKHRQPLEGWPSVEDLFVFVTVARNGGFARAALELGLSPSYISKRIAILEKCLNARLFFRNNRVMRLTPEGEN
ALGGAMQVVSEMDGFVSRLDNQRGVLAGNITINCSFGFGHKYVAEALSSFMIAYPDITVKLTLTDREVDLVEEGIDIEIR
VGDDINELYIARQLATNRRILCASPEYLERHGKPESVSALVQHDCLMIQEKNSAFGNWILTDGKQQTHCRLNGFHSSNSG
SVVLIWALKGHGITLRSEWDVAQYIERGELVRVLPQWYQEANIWAVYTRRSSSSDRIKICIDFLTEHLAQCLPGGKAPGV
L

Specific function: Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB- ygjE operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=291, Percent_Identity=41.9243986254296, Blast_Score=264, Evalue=6e-72,
Organism=Escherichia coli, GI87081978, Length=297, Percent_Identity=44.4444444444444, Blast_Score=258, Evalue=4e-70,
Organism=Escherichia coli, GI1786401, Length=300, Percent_Identity=33.6666666666667, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1787128, Length=270, Percent_Identity=28.5185185185185, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1787589, Length=289, Percent_Identity=26.643598615917, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI145693193, Length=287, Percent_Identity=29.2682926829268, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1789639, Length=288, Percent_Identity=26.3888888888889, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788706, Length=274, Percent_Identity=28.4671532846715, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1789173, Length=262, Percent_Identity=26.7175572519084, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1786448, Length=253, Percent_Identity=28.8537549407115, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1790208, Length=126, Percent_Identity=31.7460317460317, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35894; Mature: 35894

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTTPVGKKHRQPLEGWPSVEDLFVFVTVARNGGFARAALELGLSPSYISKRIAILEKCL
CCCCCCCHHCCCCCCCCCCHHHEEEEEEEECCCCEEEEHHHHCCCHHHHHHHHHHHHHHH
NARLFFRNNRVMRLTPEGENALGGAMQVVSEMDGFVSRLDNQRGVLAGNITINCSFGFGH
CCEEEEECCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEECCCH
KYVAEALSSFMIAYPDITVKLTLTDREVDLVEEGIDIEIRVGDDINELYIARQLATNRRI
HHHHHHHHHHEEECCCEEEEEEEECCCHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCEE
LCASPEYLERHGKPESVSALVQHDCLMIQEKNSAFGNWILTDGKQQTHCRLNGFHSSNSG
EECCHHHHHHCCCCHHHHHHHHHCEEEEEECCCCCCCEEEECCCCCCEEEEECEECCCCC
SVVLIWALKGHGITLRSEWDVAQYIERGELVRVLPQWYQEANIWAVYTRRSSSSDRIKIC
CEEEEEEECCCCEEEECCCCHHHHHHCCHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEH
IDFLTEHLAQCLPGGKAPGVL
HHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKTTPVGKKHRQPLEGWPSVEDLFVFVTVARNGGFARAALELGLSPSYISKRIAILEKCL
CCCCCCCHHCCCCCCCCCCHHHEEEEEEEECCCCEEEEHHHHCCCHHHHHHHHHHHHHHH
NARLFFRNNRVMRLTPEGENALGGAMQVVSEMDGFVSRLDNQRGVLAGNITINCSFGFGH
CCEEEEECCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEECCCH
KYVAEALSSFMIAYPDITVKLTLTDREVDLVEEGIDIEIRVGDDINELYIARQLATNRRI
HHHHHHHHHHEEECCCEEEEEEEECCCHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCEE
LCASPEYLERHGKPESVSALVQHDCLMIQEKNSAFGNWILTDGKQQTHCRLNGFHSSNSG
EECCHHHHHHCCCCHHHHHHHHHCEEEEEECCCCCCCEEEECCCCCCEEEEECEECCCCC
SVVLIWALKGHGITLRSEWDVAQYIERGELVRVLPQWYQEANIWAVYTRRSSSSDRIKIC
CEEEEEEECCCCEEEECCCCHHHHHHCCHHHHHHHHHHHCCCEEEEEEECCCCCCEEEEH
IDFLTEHLAQCLPGGKAPGVL
HHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]