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The map label for this gene is atpB

Identifier: 167626205

GI number: 167626205

Start: 5211418

End: 5212248

Strand: Reverse

Name: atpB

Synonym: Shal_4300

Alternate gene names: 167626205

Gene position: 5212248-5211418 (Counterclockwise)

Preceding gene: 167626206

Following gene: 167626204

Centisome position: 99.72

GC content: 40.91

Gene sequence:

>831_bases
ATGGCGACAACTGGGGATGATACGTTAACTATAACGGCTTCCGACTATATCCAGCATCACCTGACTAATGCGAAAATGTG
TTCCACTGATGGTGGGATTGCTTTTAACTATGCATGTCAAGATGCTGGATTTTGGACTTGGCACATTGACTCACTTTTAT
TTTCAGTAGGTCTAGGGGTTCTATTTTTGTGGTTATTCTACAAAGTAGGACAAAAGGCAACAATTGGCGTTCCAGGCAAG
CTTCAATGTTTCGTTGAAATGTGCGTGGAAGGTGTAGATAAAATCGTTAAAGACTCATTTCATGGGAAAAATGCGGTTAT
TGCACCATTAGGTCTAACTATTTTCGTCTGGGTTTTCCTGATGAACTTAATGGACTTGATCCCTGTTGACTTTGTACCTG
AGGCCGCCAAACGATTATTAGGCGTACCTTACCTAAAGATTGTACCTACAACTGACTTGAACGTAACTTTGGGCTTAGCT
TTGAGTGTGTTCGTGTTAATTGTTTTTTACAGTATCAAGGTTAAAGGGTTTAGTGGGTTCACTAAAGAACTGACTATGCA
GCCTTTCAATCACTGGGCTCTGATTCCAATTAACTTTGTTTTGGAAACAGTCACCTTGATTGCGAAGCCGATTTCATTAT
CGCTTCGTCTGTTTGGTAACCTGTATGCAGGTGAGTTGATCTTTATTCTGATAGCACTGATGCCTTGGTGGGCGCAGTTT
GCATTATCAGTGCCTTGGGCCATTTTCCATATTTTGGTAATTGTGCTGCAGGCGTTTATCTTCATGATGCTTACGATTGT
ATATCTAAGCATGGCACATGAAGACCATTAA

Upstream 100 bases:

>100_bases
GAAATCGTCATTTATGCCGTTATTCGTCTGCTATTTACTTGTGCTAATTGTGCCTTGGACAGTCCCTTTACACTTCAAAC
AAAATTAAGTGAGATTAATC

Downstream 100 bases:

>100_bases
TTTAATAAAATTAGTTACTTATCGGAGATAAAATGGAAACTGTAATTAGCTTTACAGCAATAGCTGTTGCAATTATGATC
GGCTTAGCAGCGCTAGGTAC

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MATTGDDTLTITASDYIQHHLTNAKMCSTDGGIAFNYACQDAGFWTWHIDSLLFSVGLGVLFLWLFYKVGQKATIGVPGK
LQCFVEMCVEGVDKIVKDSFHGKNAVIAPLGLTIFVWVFLMNLMDLIPVDFVPEAAKRLLGVPYLKIVPTTDLNVTLGLA
LSVFVLIVFYSIKVKGFSGFTKELTMQPFNHWALIPINFVLETVTLIAKPISLSLRLFGNLYAGELIFILIALMPWWAQF
ALSVPWAIFHILVIVLQAFIFMMLTIVYLSMAHEDH

Sequences:

>Translated_276_residues
MATTGDDTLTITASDYIQHHLTNAKMCSTDGGIAFNYACQDAGFWTWHIDSLLFSVGLGVLFLWLFYKVGQKATIGVPGK
LQCFVEMCVEGVDKIVKDSFHGKNAVIAPLGLTIFVWVFLMNLMDLIPVDFVPEAAKRLLGVPYLKIVPTTDLNVTLGLA
LSVFVLIVFYSIKVKGFSGFTKELTMQPFNHWALIPINFVLETVTLIAKPISLSLRLFGNLYAGELIFILIALMPWWAQF
ALSVPWAIFHILVIVLQAFIFMMLTIVYLSMAHEDH
>Mature_275_residues
ATTGDDTLTITASDYIQHHLTNAKMCSTDGGIAFNYACQDAGFWTWHIDSLLFSVGLGVLFLWLFYKVGQKATIGVPGKL
QCFVEMCVEGVDKIVKDSFHGKNAVIAPLGLTIFVWVFLMNLMDLIPVDFVPEAAKRLLGVPYLKIVPTTDLNVTLGLAL
SVFVLIVFYSIKVKGFSGFTKELTMQPFNHWALIPINFVLETVTLIAKPISLSLRLFGNLYAGELIFILIALMPWWAQFA
LSVPWAIFHILVIVLQAFIFMMLTIVYLSMAHEDH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family

Homologues:

Organism=Escherichia coli, GI1790176, Length=268, Percent_Identity=61.9402985074627, Blast_Score=319, Evalue=1e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATP6_SHEHH (B0TQG0)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001676499.1
- ProteinModelPortal:   B0TQG0
- SMR:   B0TQG0
- GeneID:   5905427
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_4300
- HOGENOM:   HBG734175
- OMA:   AGELVFM
- ProtClustDB:   PRK05815
- BioCyc:   SHAL458817:SHAL_4300-MONOMER
- HAMAP:   MF_01393
- InterPro:   IPR000568
- InterPro:   IPR023011
- Gene3D:   G3DSA:1.20.120.220
- PANTHER:   PTHR11410
- PRINTS:   PR00123
- TIGRFAMs:   TIGR01131

Pfam domain/function: PF00119 ATP-synt_A; SSF81336 ATPase_F0_A

EC number: 3.6.3.14

Molecular weight: Translated: 30829; Mature: 30698

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1220e2b0)-; HASH(0x12521cd8)-; HASH(0x12e89c28)-; HASH(0x12a7ac94)-; HASH(0x130f70b4)-; HASH(0x107fde78)-;

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTGDDTLTITASDYIQHHLTNAKMCSTDGGIAFNYACQDAGFWTWHIDSLLFSVGLGV
CCCCCCCEEEEEHHHHHHHHHCCCCEECCCCCEEEEEEECCCCEEEHHHHHHHHHHHHHH
LFLWLFYKVGQKATIGVPGKLQCFVEMCVEGVDKIVKDSFHGKNAVIAPLGLTIFVWVFL
HHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHH
MNLMDLIPVDFVPEAAKRLLGVPYLKIVPTTDLNVTLGLALSVFVLIVFYSIKVKGFSGF
HHHHHHCCCCCCHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
TKELTMQPFNHWALIPINFVLETVTLIAKPISLSLRLFGNLYAGELIFILIALMPWWAQF
HHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALSVPWAIFHILVIVLQAFIFMMLTIVYLSMAHEDH
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure 
ATTGDDTLTITASDYIQHHLTNAKMCSTDGGIAFNYACQDAGFWTWHIDSLLFSVGLGV
CCCCCCEEEEEHHHHHHHHHCCCCEECCCCCEEEEEEECCCCEEEHHHHHHHHHHHHHH
LFLWLFYKVGQKATIGVPGKLQCFVEMCVEGVDKIVKDSFHGKNAVIAPLGLTIFVWVFL
HHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHH
MNLMDLIPVDFVPEAAKRLLGVPYLKIVPTTDLNVTLGLALSVFVLIVFYSIKVKGFSGF
HHHHHHCCCCCCHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
TKELTMQPFNHWALIPINFVLETVTLIAKPISLSLRLFGNLYAGELIFILIALMPWWAQF
HHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALSVPWAIFHILVIVLQAFIFMMLTIVYLSMAHEDH
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA