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The map label for this gene is atpA2 [H]

Identifier: 167626201

GI number: 167626201

Start: 5208524

End: 5210065

Strand: Reverse

Name: atpA2 [H]

Synonym: Shal_4296

Alternate gene names: 167626201

Gene position: 5210065-5208524 (Counterclockwise)

Preceding gene: 167626202

Following gene: 167626200

Centisome position: 99.68

GC content: 46.17

Gene sequence:

>1542_bases
ATGCAACTGAATTCCACTGAAATCAGCGATCTGATTAAACAGCGGATCGAGCAGTTCAACGTCGTCAGTGAAGCTCGCAA
CGAAGGTACTATCGTTGCAGTAAGTGATGGCATCATCCGCATCCACGGTCTAGCCGATGTGATGCAGGGTGAGATGATTG
AACTGCCTGGTAACCGTTTCGCAATCGCGTTGAACTTAGAACGTGATTCTGTCGGTGCCGTAGTGATGGGGCCTTATGCT
AATTTAGCAGAAGGTGATAAAGTTAAAACAACTGGTCGTATTTTGGAAGTCCCAGTTGGCCGAGGTCTATTAGGCCGCGT
AGTCAACACATTGGGCGAGCCAATCGACGGGAAAGGACCACTCGAACACGATGGTTTCTCTCCTGTTGAAGTTATCGCAC
CAGGTGTTATTGAACGTAAGTCAGTAGATCAACCAGTGCAAACTGGTTATAAAGCCGTTGACTCTATGATCCCAATCGGT
CGTGGACAACGTGAATTGATCATTGGTGACCGTCAGATCGGTAAAACCGCTCTTGCGATCGATGCCATCATCAATCAAAA
AGATACTGGCATTAAGTGTGTATACGTAGCAGTAGGCCAAAAGGCTTCTACCATCGCTAACGTGGTACGCAAGCTAGATG
AACATGGCGCTTTGGCGAACACCATTGTTGTTGTTGCTACAGCTTCTGAAGCTGCTGCTCTACAATATTTGGCTCCATAC
TCTGGTTGTTCAATGGGTGAATATTTCCGCGACCGCGGTGAAGATTCACTGATTGTCTATGATGATCTTTCTAAGCAAGC
AGTTGCTTACCGTCAGATCTCATTGCTTCTTAAGCGTCCACCTGGACGTGAAGCATACCCAGGTGATGTATTCTATCTAC
ACTCTCGTCTGTTAGAACGTGCTTCACGTGTTAACGCTGAGTATGTTGAGAAGTTCACTAAAGGCGAAGTGAAAGGCCAA
ACTGGTTCTTTGACTGCATTGCCGATTATTGAAACTCAAGCGGGTGACGTTTCTGCATTCGTACCGACTAACGTAATTTC
GATTACTGATGGTCAGATCTTCCTTGAAACCGATCTATTTAACTCTGGACTACGTCCAGCTGTTAACCCTGGTATCTCAG
TTTCTCGTGTTGGTGGTGCGGCTCAGACTAAGATCATCAAGAAACTGTCAGGCGGTATTCGTAGCGCACTTGCACAGTAT
CGAGAGCTTGCAGCGTTCTCACAGTTTGCATCTGACTTAGATGATGCAACACGTGCTCAGCTTGAGCATGGTGAGCGTGT
TACTGAACTTATGAAGCAAAAGCAATACGCCCCTATGAGCGTAGCTAATCAGGCTGTGTCTATTTTCTCAGCTGAAAAAG
GTTACCTAAAGAGCGTAGAGCTTAATAAGATTGGTGATTTCGAAGCATCTCTGCTCTCTTTCATGAACAGCGAGCATGCT
GACCTAATGAAGACCATTAACGATACTGGCGATTATAACGCTGATATCGAAGGTGAGTTGAAGGCCGGCCTCGATAAGTT
CGTCGAAACCCAAACCTGGTAA

Upstream 100 bases:

>100_bases
GTGTAATTATCACGGCAGGAGACTTAGTCATTGATGGCTCGGTCCGCGGAAAAGTTTCGCGTCTGTCTGATACGCTGCAG
TCGTAATTGGGAGTTTGAGC

Downstream 100 bases:

>100_bases
TCGAAAGAGGTGTCGTAAGACACCTCAGGTCCAGATTGGAGAGTTAAGATGGCCAACGCTAAAGAGATTAAAACCAAGAT
CGCGAGTGTTAAAAACACTC

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha 2; F-ATPase subunit alpha 2 [H]

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MQLNSTEISDLIKQRIEQFNVVSEARNEGTIVAVSDGIIRIHGLADVMQGEMIELPGNRFAIALNLERDSVGAVVMGPYA
NLAEGDKVKTTGRILEVPVGRGLLGRVVNTLGEPIDGKGPLEHDGFSPVEVIAPGVIERKSVDQPVQTGYKAVDSMIPIG
RGQRELIIGDRQIGKTALAIDAIINQKDTGIKCVYVAVGQKASTIANVVRKLDEHGALANTIVVVATASEAAALQYLAPY
SGCSMGEYFRDRGEDSLIVYDDLSKQAVAYRQISLLLKRPPGREAYPGDVFYLHSRLLERASRVNAEYVEKFTKGEVKGQ
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLFNSGLRPAVNPGISVSRVGGAAQTKIIKKLSGGIRSALAQY
RELAAFSQFASDLDDATRAQLEHGERVTELMKQKQYAPMSVANQAVSIFSAEKGYLKSVELNKIGDFEASLLSFMNSEHA
DLMKTINDTGDYNADIEGELKAGLDKFVETQTW

Sequences:

>Translated_513_residues
MQLNSTEISDLIKQRIEQFNVVSEARNEGTIVAVSDGIIRIHGLADVMQGEMIELPGNRFAIALNLERDSVGAVVMGPYA
NLAEGDKVKTTGRILEVPVGRGLLGRVVNTLGEPIDGKGPLEHDGFSPVEVIAPGVIERKSVDQPVQTGYKAVDSMIPIG
RGQRELIIGDRQIGKTALAIDAIINQKDTGIKCVYVAVGQKASTIANVVRKLDEHGALANTIVVVATASEAAALQYLAPY
SGCSMGEYFRDRGEDSLIVYDDLSKQAVAYRQISLLLKRPPGREAYPGDVFYLHSRLLERASRVNAEYVEKFTKGEVKGQ
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLFNSGLRPAVNPGISVSRVGGAAQTKIIKKLSGGIRSALAQY
RELAAFSQFASDLDDATRAQLEHGERVTELMKQKQYAPMSVANQAVSIFSAEKGYLKSVELNKIGDFEASLLSFMNSEHA
DLMKTINDTGDYNADIEGELKAGLDKFVETQTW
>Mature_513_residues
MQLNSTEISDLIKQRIEQFNVVSEARNEGTIVAVSDGIIRIHGLADVMQGEMIELPGNRFAIALNLERDSVGAVVMGPYA
NLAEGDKVKTTGRILEVPVGRGLLGRVVNTLGEPIDGKGPLEHDGFSPVEVIAPGVIERKSVDQPVQTGYKAVDSMIPIG
RGQRELIIGDRQIGKTALAIDAIINQKDTGIKCVYVAVGQKASTIANVVRKLDEHGALANTIVVVATASEAAALQYLAPY
SGCSMGEYFRDRGEDSLIVYDDLSKQAVAYRQISLLLKRPPGREAYPGDVFYLHSRLLERASRVNAEYVEKFTKGEVKGQ
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLFNSGLRPAVNPGISVSRVGGAAQTKIIKKLSGGIRSALAQY
RELAAFSQFASDLDDATRAQLEHGERVTELMKQKQYAPMSVANQAVSIFSAEKGYLKSVELNKIGDFEASLLSFMNSEHA
DLMKTINDTGDYNADIEGELKAGLDKFVETQTW

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=512, Percent_Identity=55.2734375, Blast_Score=554, Evalue=1e-158,
Organism=Homo sapiens, GI4757810, Length=512, Percent_Identity=55.2734375, Blast_Score=554, Evalue=1e-158,
Organism=Homo sapiens, GI32189394, Length=362, Percent_Identity=26.5193370165746, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI19913428, Length=316, Percent_Identity=27.5316455696203, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI19913426, Length=313, Percent_Identity=26.8370607028754, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI19913424, Length=267, Percent_Identity=27.7153558052434, Blast_Score=76, Evalue=9e-14,
Organism=Escherichia coli, GI1790172, Length=513, Percent_Identity=85.3801169590643, Blast_Score=914, Evalue=0.0,
Organism=Escherichia coli, GI1790170, Length=340, Percent_Identity=26.4705882352941, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788251, Length=387, Percent_Identity=24.8062015503876, Blast_Score=105, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI71988063, Length=515, Percent_Identity=55.3398058252427, Blast_Score=554, Evalue=1e-158,
Organism=Caenorhabditis elegans, GI71988080, Length=515, Percent_Identity=55.3398058252427, Blast_Score=553, Evalue=1e-158,
Organism=Caenorhabditis elegans, GI71988074, Length=515, Percent_Identity=51.4563106796116, Blast_Score=504, Evalue=1e-143,
Organism=Caenorhabditis elegans, GI17510931, Length=368, Percent_Identity=25.2717391304348, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI25144756, Length=459, Percent_Identity=23.3115468409586, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17570191, Length=311, Percent_Identity=26.3665594855305, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17565854, Length=262, Percent_Identity=26.7175572519084, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17509265, Length=47, Percent_Identity=65.9574468085106, Blast_Score=72, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6319370, Length=513, Percent_Identity=53.9961013645224, Blast_Score=562, Evalue=1e-161,
Organism=Saccharomyces cerevisiae, GI6322581, Length=474, Percent_Identity=25.1054852320675, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6319603, Length=376, Percent_Identity=27.1276595744681, Blast_Score=111, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24658560, Length=514, Percent_Identity=54.0856031128405, Blast_Score=545, Evalue=1e-155,
Organism=Drosophila melanogaster, GI281361666, Length=354, Percent_Identity=26.5536723163842, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24646341, Length=354, Percent_Identity=26.5536723163842, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI17136796, Length=354, Percent_Identity=26.5536723163842, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24638766, Length=424, Percent_Identity=24.7641509433962, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI28574560, Length=404, Percent_Identity=24.2574257425743, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24583992, Length=338, Percent_Identity=25.4437869822485, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24583988, Length=267, Percent_Identity=27.7153558052434, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24583986, Length=267, Percent_Identity=27.7153558052434, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24583984, Length=267, Percent_Identity=27.7153558052434, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI20129479, Length=375, Percent_Identity=24.5333333333333, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 55449; Mature: 55449

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLNSTEISDLIKQRIEQFNVVSEARNEGTIVAVSDGIIRIHGLADVMQGEMIELPGNRF
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEECHHHHHCCCEEECCCCEE
AIALNLERDSVGAVVMGPYANLAEGDKVKTTGRILEVPVGRGLLGRVVNTLGEPIDGKGP
EEEEEECCCCCCEEEECCCCCCCCCCCEECCCCEEEECCCCCHHHHHHHHHCCCCCCCCC
LEHDGFSPVEVIAPGVIERKSVDQPVQTGYKAVDSMIPIGRGQRELIIGDRQIGKTALAI
CCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCHHHCHHHHHH
DAIINQKDTGIKCVYVAVGQKASTIANVVRKLDEHGALANTIVVVATASEAAALQYLAPY
HHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEEECCHHHHHHHHCCC
SGCSMGEYFRDRGEDSLIVYDDLSKQAVAYRQISLLLKRPPGREAYPGDVFYLHSRLLER
CCCCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
ASRVNAEYVEKFTKGEVKGQTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLF
HHHCCHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEECHH
NSGLRPAVNPGISVSRVGGAAQTKIIKKLSGGIRSALAQYRELAAFSQFASDLDDATRAQ
CCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEHGERVTELMKQKQYAPMSVANQAVSIFSAEKGYLKSVELNKIGDFEASLLSFMNSEHA
HHCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHCCCHH
DLMKTINDTGDYNADIEGELKAGLDKFVETQTW
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQLNSTEISDLIKQRIEQFNVVSEARNEGTIVAVSDGIIRIHGLADVMQGEMIELPGNRF
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEECHHHHHCCCEEECCCCEE
AIALNLERDSVGAVVMGPYANLAEGDKVKTTGRILEVPVGRGLLGRVVNTLGEPIDGKGP
EEEEEECCCCCCEEEECCCCCCCCCCCEECCCCEEEECCCCCHHHHHHHHHCCCCCCCCC
LEHDGFSPVEVIAPGVIERKSVDQPVQTGYKAVDSMIPIGRGQRELIIGDRQIGKTALAI
CCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCHHHCHHHHHH
DAIINQKDTGIKCVYVAVGQKASTIANVVRKLDEHGALANTIVVVATASEAAALQYLAPY
HHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEEECCHHHHHHHHCCC
SGCSMGEYFRDRGEDSLIVYDDLSKQAVAYRQISLLLKRPPGREAYPGDVFYLHSRLLER
CCCCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
ASRVNAEYVEKFTKGEVKGQTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLF
HHHCCHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEECHH
NSGLRPAVNPGISVSRVGGAAQTKIIKKLSGGIRSALAQYRELAAFSQFASDLDDATRAQ
CCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEHGERVTELMKQKQYAPMSVANQAVSIFSAEKGYLKSVELNKIGDFEASLLSFMNSEHA
HHCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHCCCHH
DLMKTINDTGDYNADIEGELKAGLDKFVETQTW
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA