Click here to switch to the map view.

The map label for this gene is gltS [H]

Identifier: 167626105

GI number: 167626105

Start: 5103713

End: 5104936

Strand: Reverse

Name: gltS [H]

Synonym: Shal_4200

Alternate gene names: 167626105

Gene position: 5104936-5103713 (Counterclockwise)

Preceding gene: 167626106

Following gene: 167626104

Centisome position: 97.67

GC content: 45.83

Gene sequence:

>1224_bases
ATGAATACTGTATATTCAATCGGAGAACTAGAATCGTTTTTGGTCGCCATCTTGGTATTGTTTATCGGCCACTCAGTTAA
TCGTCACGTTCCTTTTTTCAAAAAATATAACATCCCAGAGCCCATTATCGGCGGCCTGGTTGTCGCAGCAGTGATTACTG
TTCTTCATTTTCAGAATATTACACTAGCGTTTTCCTTGCCAATGCAAAACACGCTGATGCTGATGTTCTTCAGCACTGTG
GGCCTTGCCGCCAGTTACAGGTTGCTTGCCCGTGGTGGTAAAAAAGTCTTTATTTTTCTTGGCATTGCCTCGATTTACAT
CATCTTGCAAAATGCGGTGGGTGTGAGTTTGGCGGCTGCATTAGGCTTAGAACCCTTGATGGGATTAGTTGCTGGTTCTA
TCACGCTATCTGGTGGCCATGGTACTGGAGCTGCTTGGTCGCAGACGTTTGCCGAGCAATACAACATGAATACGCTAGAG
TTCGCCATGGCTGCCGCAACATTTGGGTTGGTGATGGGCGGTATCATCGGCGGCCCAGTGGCACAGAGGCTTATTGATAA
GAATAAGCTGGAATCTTCTTATGGTATCGGTGGTAACCATCATAAAGACCACCCCGATCTAGTAACCTATGATCAGTTAG
AGATCGATAATGTCACCGCTAAGAGTGTGTTAGAAACGCTGTTTATCATCATGCTTTGTGTCGCTGGGGCTAAGTGGGTA
GGGCACTTAGTCGCTAGTTTCGATATTAGTTGGCTGAAGATGCCTGACTTCGTGTATGCGCTATTTATCGGGGTGATGAT
CACTAACTTCACCGAGATGACGCGCGGTTACAAGATGAATAATGAATGTGTCGATATCTTAGGCACAGTCGCCTTATCTC
TGTTCCTTGCTATGGCGTTAATGAGCTTAAAGCTATGGGAAATTTTTGACCTCGCGATTCCGCTATTGATCATCTTAATG
GTACAGACGGTCGTTTTGGCCTGTTTTGCTTATTTTGTTACGTTTAGAGTGATGGGCTCAAATTATGATGCTGCCGTGAT
GGCTGGAGGGCATTGTGGTTTTGGTATGGGGGCTACGCCAACAGCGGTTATGAATATGGGCGCACTGGTTTCCCGAAATG
GCCCTTCACCACAAGCCTTCATGGTGGTGCCGATTGTCGGTGCCTTCTTTATCGATATCGTTAACTTGGTAGTACTGCAA
GGCTATATCAAGTTCATTTTGTAG

Upstream 100 bases:

>100_bases
GACACGGCTAATATTATTTACCCTAATGAATATGCCAGAATAGCCGGCTAATTTTGGTTTTGTAGGTTGTTTACTACAAA
ACCTAACGGATAGGAGTTTC

Downstream 100 bases:

>100_bases
TAATTTAGTTTCACTTTAAATCAGGCACGCATAAGCGTGCCTTTTTATTGGACTAGAATTAATTTTGATCATGGTGCAAT
CAATAACGATTTTGATTCGT

Product: sodium/glutamate symporter

Products: Na (I) [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: Glutamate permease [H]

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MNTVYSIGELESFLVAILVLFIGHSVNRHVPFFKKYNIPEPIIGGLVVAAVITVLHFQNITLAFSLPMQNTLMLMFFSTV
GLAASYRLLARGGKKVFIFLGIASIYIILQNAVGVSLAAALGLEPLMGLVAGSITLSGGHGTGAAWSQTFAEQYNMNTLE
FAMAAATFGLVMGGIIGGPVAQRLIDKNKLESSYGIGGNHHKDHPDLVTYDQLEIDNVTAKSVLETLFIIMLCVAGAKWV
GHLVASFDISWLKMPDFVYALFIGVMITNFTEMTRGYKMNNECVDILGTVALSLFLAMALMSLKLWEIFDLAIPLLIILM
VQTVVLACFAYFVTFRVMGSNYDAAVMAGGHCGFGMGATPTAVMNMGALVSRNGPSPQAFMVVPIVGAFFIDIVNLVVLQ
GYIKFIL

Sequences:

>Translated_407_residues
MNTVYSIGELESFLVAILVLFIGHSVNRHVPFFKKYNIPEPIIGGLVVAAVITVLHFQNITLAFSLPMQNTLMLMFFSTV
GLAASYRLLARGGKKVFIFLGIASIYIILQNAVGVSLAAALGLEPLMGLVAGSITLSGGHGTGAAWSQTFAEQYNMNTLE
FAMAAATFGLVMGGIIGGPVAQRLIDKNKLESSYGIGGNHHKDHPDLVTYDQLEIDNVTAKSVLETLFIIMLCVAGAKWV
GHLVASFDISWLKMPDFVYALFIGVMITNFTEMTRGYKMNNECVDILGTVALSLFLAMALMSLKLWEIFDLAIPLLIILM
VQTVVLACFAYFVTFRVMGSNYDAAVMAGGHCGFGMGATPTAVMNMGALVSRNGPSPQAFMVVPIVGAFFIDIVNLVVLQ
GYIKFIL
>Mature_407_residues
MNTVYSIGELESFLVAILVLFIGHSVNRHVPFFKKYNIPEPIIGGLVVAAVITVLHFQNITLAFSLPMQNTLMLMFFSTV
GLAASYRLLARGGKKVFIFLGIASIYIILQNAVGVSLAAALGLEPLMGLVAGSITLSGGHGTGAAWSQTFAEQYNMNTLE
FAMAAATFGLVMGGIIGGPVAQRLIDKNKLESSYGIGGNHHKDHPDLVTYDQLEIDNVTAKSVLETLFIIMLCVAGAKWV
GHLVASFDISWLKMPDFVYALFIGVMITNFTEMTRGYKMNNECVDILGTVALSLFLAMALMSLKLWEIFDLAIPLLIILM
VQTVVLACFAYFVTFRVMGSNYDAAVMAGGHCGFGMGATPTAVMNMGALVSRNGPSPQAFMVVPIVGAFFIDIVNLVVLQ
GYIKFIL

Specific function: Catalyzes the sodium-dependent uptake of extracellular glutamate [H]

COG id: COG0786

COG function: function code E; Na+/glutamate symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gltS symporter family [H]

Homologues:

Organism=Escherichia coli, GI1790085, Length=385, Percent_Identity=48.5714285714286, Blast_Score=303, Evalue=1e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004445 [H]

Pfam domain/function: PF03616 Glt_symporter [H]

EC number: NA

Molecular weight: Translated: 43926; Mature: 43926

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTVYSIGELESFLVAILVLFIGHSVNRHVPFFKKYNIPEPIIGGLVVAAVITVLHFQNI
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHCCE
TLAFSLPMQNTLMLMFFSTVGLAASYRLLARGGKKVFIFLGIASIYIILQNAVGVSLAAA
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHH
LGLEPLMGLVAGSITLSGGHGTGAAWSQTFAEQYNMNTLEFAMAAATFGLVMGGIIGGPV
HHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCHHH
AQRLIDKNKLESSYGIGGNHHKDHPDLVTYDQLEIDNVTAKSVLETLFIIMLCVAGAKWV
HHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCEEECCCHHHHHHHHHHHHHHHHHHHHHH
GHLVASFDISWLKMPDFVYALFIGVMITNFTEMTRGYKMNNECVDILGTVALSLFLAMAL
HHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
MSLKLWEIFDLAIPLLIILMVQTVVLACFAYFVTFRVMGSNYDAAVMAGGHCGFGMGATP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCH
TAVMNMGALVSRNGPSPQAFMVVPIVGAFFIDIVNLVVLQGYIKFIL
HHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MNTVYSIGELESFLVAILVLFIGHSVNRHVPFFKKYNIPEPIIGGLVVAAVITVLHFQNI
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHCCE
TLAFSLPMQNTLMLMFFSTVGLAASYRLLARGGKKVFIFLGIASIYIILQNAVGVSLAAA
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHH
LGLEPLMGLVAGSITLSGGHGTGAAWSQTFAEQYNMNTLEFAMAAATFGLVMGGIIGGPV
HHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCHHH
AQRLIDKNKLESSYGIGGNHHKDHPDLVTYDQLEIDNVTAKSVLETLFIIMLCVAGAKWV
HHHHHHHHHCCCCCCCCCCCCCCCCCCEEECCEEECCCHHHHHHHHHHHHHHHHHHHHHH
GHLVASFDISWLKMPDFVYALFIGVMITNFTEMTRGYKMNNECVDILGTVALSLFLAMAL
HHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
MSLKLWEIFDLAIPLLIILMVQTVVLACFAYFVTFRVMGSNYDAAVMAGGHCGFGMGATP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCH
TAVMNMGALVSRNGPSPQAFMVVPIVGAFFIDIVNLVVLQGYIKFIL
HHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-glutamate [Periplasm] = Na (I) [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]